대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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- Pages.233.1-233.1
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- 2002
Total synthesis of deoxy-azasugars
- Pyun, Sung-Jae (College of Pharmacy, Sungkyunkwan University) ;
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Oh, Chang-Young
(College of Pharmacy, Sungkyunkwan University) ;
- Lee, Kee-Young (College of Pharmacy, Sungkyunkwan University) ;
- Kim, Yong-Hyun (College of Pharmacy, Sungkyunkwan University) ;
- Lee, Yiu-Suk (College of Pharmacy, Sungkyunkwan University) ;
- Pharm, Van-Thoai (College of Pharmacy, Sungkyunkwan University) ;
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Ham, Won-Hun
(College of Pharmacy, Sungkyunkwan University)
- 발행 : 2002.10.01
초록
Azasugars, which have been called the "sugar-shaped" alkaloids from plants. are reversible. competitive inhibitors of glycosidases. The purpose of these natural products is possibly to inhibit the carbohydrate metabolism and consequently the growth of plant consuming pests. Since selective glycosidase inhibitors have a large number of interesting potential applications including treatment of AIDS, diabetes. and tumor metastasis. they have received a considerable attentions. (omitted)
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