Cellular Factors Involved in Methylmercury Toxicity in Yeast

  • Naganuma, Akira (Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University)
  • Published : 2002.10.01

Abstract

Methylmercury causes severe central nervous system disorders. Despite the efforts of many researchers, the mechanisms involved in methylmercury toxicity and the defense against this toxicity remain unknown. We focused on the fact that drug resistance is sometimes involved in elevation of the concentration of the intracellular target of the drug. (omitted)

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