Characterization of Mouse Peroxiredoxin III Genomic DNA and Its Expression

  • Lee, Tae-Hoon (Laboratory of Animal Developmental Biotechnology Korea Research Institute of Bioscience and Biotechnology) ;
  • Kim, Sun-Uk (Laboratory of Animal Developmental Biotechnology Korea Research Institute of Bioscience and Biotechnolog) ;
  • Lee, Kyung-Kwang (Laboratory of Animal Developmental Biotechnology Korea Research Institute of Bioscience and Biotechnolog) ;
  • Yu, Dae-Yeul (Laboratory of Animal Developmental Biotechnology Korea Research Institute of Bioscience and Biotechnology)
  • Published : 2002.06.01

Abstract

Peroxiredoxins (Prxs) possess protective activity against oxygen radicals generated by thiol-catalyzed oxidative systems. We already reported the genomic structure and its expression of mouse Prx Ⅰ, Ⅱ, and 1-Cys Prx. However, the Prx Ⅲ has not been determined. That was initially defined transiently expressed gene, mouse MER5, of murine erythroleukaemia cell differentiation. In addition, this protein was recently redefined a member of the thiol-specific antioxidant gene family. (omitted)

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