Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
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Estimating Benchmark Dose and Permissible Intake Level Using Subchronic Toxicity Data of Aristolochia Contorta

  • Lee, Hyomin (Division of Risk Assessment, Department of General Toxicology, National Institute of Toxicology Research) ;
  • Eunkyung Yoon (Division of Risk Assessment, Department of General Toxicology, National Institute of Toxicology Research) ;
  • Myungsil Hwang (Division of Risk Assessment, Department of General Toxicology, National Institute of Toxicology Research) ;
  • Lee, Geunyung (Division of Risk Assessment, Department of General Toxicology, National Institute of Toxicology Research) ;
  • Jisun Yang (Division of Risk Assessment, Department of General Toxicology, National Institute of Toxicology Research) ;
  • Kihwa Yang (Risk Assessment, Department of General Toxicology, National Institute of Toxicology Research) ;
  • Kwangsup Kil (Assessment, Department of General Toxicology, National Institute of Toxicology Research)
  • Published : 2002.11.01
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Abstract

Occurrence of Chinese Herbs Nephropathy (CHN) has been reported in young women who had taken a slimming pills containing some chinese herbs. Aristolochic acid (AA) known as a carcinogen, was suspected as the major causal factor of CHN. AA is major component of fruit of A. contorta was used in Korean Traditional Medicine.(omitted)

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