Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
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STUDIES ON THE SUBACUTE TOXICITY AND TOXICOKINETICS OF DW-224a, AFTER SINGLE AND 4-WEEK REPEATED ORAL ADMINISTRATION IN DOGS

  • Junghee Han (Department of Toxicology and Toxicokinetics, Korea Institute of Toxicology) ;
  • Cha, Shin-Woo (Department of Toxicology and Toxicokinetics, Korea Institute of Toxicology) ;
  • Chung, Moon-Koo (Department of Toxicology and Toxicokinetics, Korea Institute of Toxicology) ;
  • Han, Sang-Seop (Department of Toxicology and Toxicokinetics, Korea Institute of Toxicology)
  • Published : 2002.11.01
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Abstract

The subacute toxicities and toxicokinetics of a new fluoroquinolone antibiotics, DW-224a, were evaluated after single (at the 1st day) and 4-week (at the 28th day) oral administration of the drug, in doses of 0 (to serve as a control), 10, 30 and 90 mg/kg/day, to male and female dogs (n = 3 for male and female dogs for each dose).(omitted)

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