URINARY COTININE AND 1-HYDROXYPYRENE-GLUCURONIDE AS BIOMARKERS OF ENVIRONMENTAL TOBACCO SMOKE

  • Lee, Kyoung-Ho (Department of Preventive Medicine, Seoul National University College of Medicine) ;
  • Cho, Soo-Hun (Department of Preventive Medicine, Seoul National University College of Medicine) ;
  • Kwon, Ho-Jang (Department of of Preventive Medicine, Dankook University College of Medicine) ;
  • Hwang, Seung-Sik (Department of Preventive Medicine, Seoul National University College of Medicine) ;
  • Deahee Kang (Department of Preventive Medicine, Seoul National University College of Medicine)
  • Published : 2002.11.01

Abstract

This study was conducted to compare two biomarkers of environmental tobacco smoke (ETS); urinary cotinine and 1-hydroxypyrene-glucuronide (1-OHPG). Urine samples were collected from 102 junior high school students. Urinary cotinine was determined by GC and urinary 1-OHPG was assayed by synchronous fluorescence spectroscopy (SFS) after immuno-affinity purification using monoclonal antibody 8E11.(omitted)

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