Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
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Tributyltin Induces Orphan Nuclear Receptor Nur77 Gene Expression and Cell Death in Testicular cell line (TM3)

  • Lee, Kyung-Hee (Department of Biology, Chonnam National University) ;
  • Lee, Kyung-Jin (Department of Biology, Chonnam National University) ;
  • Bin, Im-Wook (Department of Biology, Chonnam National University) ;
  • Park, Hueng-Sik (Hormone Research Center, Chonnam National University) ;
  • Lee, Jong-Bin (Department of Biology, Chonnam National University)
  • Published : 2002.11.01
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Abstract

A clear association between occupational tributyltin (TBT) exposure and testicular cell line, TM3 has been observed in mouse. In the present study, we have investigated cytotoxic effects of TBT on Significant cytolethality was observed in TM3 cells in a time- and concentration-dependent manner when measured by MTT assays. (omitted)

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