Molecular Cloning and Characterization of Mouse Cardiac Triadin Isoforms

  • Hong, Chang-Soo (Department of Life Science, Kwangju Institute of Science and Technology) ;
  • Ji, Jung-Hoon (Department of Life Science, Kwangju Institute of Science and Technolog) ;
  • Jung, Dai-Hyun (Department of Life Science, Kwangju Institute of Science and Technolog) ;
  • Kim, Do-Han (Department of Life Science, Kwangju Institute of Science and Technology)
  • 발행 : 2001.06.01

초록

Triadin is a ryanodine receptor and calsequestrin binding protein located in junctional sarcoplasmic reticulum of striated muscles. In the present study, mouse cardiac triadin cDNAs have been identified by cDNA library screening and RT-PCR. The deduced aa sequences show that the three isoforms consist of 277, 293 and 305 aa giving rise to the molecular weights of approximately 31,414,33,066, and 34,328 respectively.(omtted)

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