한국생물물리학회:학술대회논문집 (Proceedings of the Korean Biophysical Society Conference)

한국생물물리학회 (The Korean Biophysical Society)
권호 표지

Effect of Carboplatin in Combination with Hyperthermia on Cell Death in Human Retinoblastoma Cell Lines

  • Park, H.J. (Department of Microbiology, College of Medicine, Inha University) ;
  • Park, S.R. (Department of Physiology, College of Medicine, Inha Universit) ;
  • Park, E.K. (Department of Therapeutic Radiology, College of Medicine, Ulsan Universit) ;
  • Chung, H.S. (Department of Microbiology, College of Medicine, Inha Universit) ;
  • H.E.Ahn (Department of Physiology, College of Medicine, Inha Universit) ;
  • Y.H.Rhee (Department of Therapeutic Radiology, College of Medicine, Ulsan Universit) ;
  • Ha, S.W. (Department of Therapeutic Radiology, College of Medicine, Seoul National Universit) ;
  • Lim, B.U. (Department of Microbiology, College of Medicine, Inha University)
  • 발행 : 2001.06.01
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초록

We have investigated the effect of environmental acidity on the induction of apoptosis caused by heat and carboplatin alone or combined. The degree of apoptosis after heating at 42.5$^{\circ}C$ for 1h in pH 6.6 medium was greater than that in pH 7.5 medium in WERI human retinobalstoma cells. When heated in the same pH medium, more apoptosis occurred in the WERI cells than in the Y79 human retinoblastoma cells.(omitted)

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