한국독성학회:학술대회논문집 (Proceedings of the Korean Society of Toxicology Conference)
- 한국독성학회 2001년도 International Symposium on Signal transduction in Toxicology
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- Pages.96-106
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- 2001
THE ESSENTIAL ROLE OF PI3-KINASE IN THE INDUCTION OF GLUTATHIONE S-TRANSFERASE BY TERT-BUTYLHYDROQUINONE AND OLTIPRAZ: DIFFERENTIAL EFFECTS ON Nrf2/ARE ACTIVATION
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Kim, Sang-Geon
(College of Pharmacy, Seoul National University)
;
- Kang, Keon-Wook (College of Pharmacy, Seoul National University)
- 발행 : 2001.05.01
초록
The phase II detoxifying enzymes are inducible by a variety of compounds and play an essential role for the protection of cells. Many of chemoprotective agents trigger cellular signals for the phase II enzyme induction, which subsequently activate gene transcription through ARE activation.(omitted)
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