Proceedings of the KOSOMBE Conference (대한의용생체공학회:학술대회논문집)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
권호 표지

Regional variation in vertebral bone density and structure due to osteoporosis

골다공증에 따른 부위별 골 밀도와 구조의 변화

  • Park, J.H. (Department of Biomedical Engineering, Inje University) ;
  • Lee, S.J. (Department of Biomedical Engineering, Inje University) ;
  • Chang, H. (Department of Orthopedic Surgery, Uijongbu St Mary's Hospital) ;
  • Choi, W.S. (Department of Orthopedic Surgery, Uijongbu St Mary's Hospital) ;
  • Kang, C. (Department of Radiology, Kangnam St. Mary's Hospital, The Catholic University of Korea) ;
  • Tack, G.R. (Department of Biomedical Engineering, Konkuk University)
  • 박정홍 (인제대학교 의용공학과) ;
  • 이성재 (인제대학교 의용공학과) ;
  • 장한 (가톨릭대학교 의과대학 의정부 성모병원 정형외과) ;
  • 최우성 (가톨릭대학교 의과대학 의정부 성모병원 정형외과) ;
  • 강철 (가톨릭대학교 의과대학 강남 성모병원 진단방사선과) ;
  • 탁계례 (건국대학교 의과대학 의공학과)
  • Published : 1998.11.20
Download PDF
⟨ Previous Next ⟩

Abstract

In this study, regional variation in vertebral bone density due to osteoporosis were investigated using a method that employs images from QCT. QCT images(1mm thick slices) of the first lumbar vertebra from a normal person (23/M, BMD=139.8mg/ml) and from an osteoporotic patient (54/F, BMD=82.0mg/ml) were obtained. Uniform settings (140kVp, 204mA) were used and images of 300 Hounsfield Unit or greater were selectied to filler out soft tissue interference. To assess the regional variation of the area fraction the vertebral body was divided into 3 layers and each layer contained 9 regions. Area faction was calculated based on image analysis data. Our results showed that the area fraction at the middle of the vertebra was quite lower than the endplate and peripheral regions, but the area fraction values from the osteoporotic patient were uniform throughout the entire height of the vertebral body, which indicates the significant drop of BMD had occurred near both end-plates due to the osteoporosis, especially at the peripheral regions. Our results suggest the susceptability of the vertebrae to compression fracture types in osteoporotic spine.

Keywords