Free Radicals during the Oxidation and Reduction of Methylglyoxal-Modified Protein

  • Lee, Cheolju (Department of Microbiology, College of Natural Sciences and the Research Center for Molecular Microbiology, Seoul National University) ;
  • Kang, Sa-Ouk (Department of Microbiology, College of Natural Sciences and the Research Center for Molecular Microbiology, Seoul National University)
  • Published : 1997.07.01

Abstract

Protein glycation was studied with bovine serum albumin (BSA) as a model protein and methylglyoxal, a 3-carbon ${\alpha}$-ketoaldehyde. Methylglyoxal reacted with BSA, forming a radical as observed in the reaction of methylglyoxal wtih L-alanine or N-acetyl-L-lysine.(omitted)

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