Purinergic-mediated Calcium Homeostasis and Dopamine R~lease in PC 12 Cells: Effect of Ethanol

  • Kim, Won-Ki (Dept. of Pharmacology, Ewha Woman′s University Medical School)
  • Published : 1997.07.01

Abstract

Extracelluar ATP evokes many biological processes, including neuronal excitation and neurotransmitter secretion, through activation of purinergic P2 receptors. Although excitatory and inhibitory receptor-operated channels (ROC) and voltage-dependent calcium channels (VDCC) have been reported to be altered by acute and chronic exposure to ethanol, little is known of the ethanol effects on purinergic receptor-operated channels in neuronal cells.(omitted)

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