Proceedings of the Korean Biophysical Society Conference (한국생물물리학회:학술대회논문집)

The Korean Biophysical Society (한국생물물리학회)
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Structural Mechanism for the Cellular Redox Regulation by the Thiol Specific Antioxidant Proteins

  • Park, Hee-Jeong (Division of Protein Engineering, Korea Research Institute of Biosci. ＆ Biotech.) ;
  • Kang, Sang-Won (Laboratory of Biochemistry, NHLB) ;
  • Rhee, Sue-Goo (Laboratory of Biochemistry, NHLB) ;
  • Ryu, Seong-Eon (Division of Protein Engineering, Korea Research Institute of Biosci. ＆ Biotech.)
  • Published : 1997.07.01
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Abstract

Recent studies indicate that hydrogen peroxide (H$_2$O$_2$), which is one of the reactive oxygen species involved in the oxidative stress, is an intracellular secondary messenger in the signal transduction. A novel family of thiol specific antioxidant (TSA) enzymes with a peroxidase activity shows no sequence homology to previously known antioxidant enzymes.(omitted)

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