Proceedings of the Korean Biophysical Society Conference (한국생물물리학회:학술대회논문집)

The Korean Biophysical Society (한국생물물리학회)
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INTERACTION OF TENECIN FRAGMENTS WITH LIPOSOMES

  • Park, Myeong-Jun (Drug Delivery Research Lab. Protein Chemistry Lab., Mogam Biotechnology Research Institute) ;
  • Cho, Hyun-Sook (Drug Delivery Research Lab. Protein Chemistry Lab., Mogam Biotechnology Research Institut) ;
  • Hong, Sung-Yu (Drug Delivery Research Lab. Protein Chemistry Lab., Mogam Biotechnology Research Institut) ;
  • Yoon, Jeong-Hyeok (Drug Delivery Research Lab. Protein Chemistry Lab., Mogam Biotechnology Research Institut) ;
  • Lee, Keun-Hyeong (Drug Delivery Research Lab. Protein Chemistry Lab., Mogam Biotechnology Research Institut) ;
  • Moon, Hong-Mo (Drug Delivery Research Lab. Protein Chemistry Lab., Mogam Biotechnology Research Institut) ;
  • Cheong, Hong-Seok (Drug Delivery Research Lab. Protein Chemistry Lab., Mogam Biotechnology Research Institute)
  • Published : 1996.07.01
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Abstract

Tenecin fragments are antimicrobial and antifungal peptide from Tenebrio molitor with highly positive charged amino acid residues. To elucidate their membrane selectivity and molecular mechanism, various forms of tenecin fragments were synthesized, and their interaction with acidic phospholipid, Gram (+), fungal and human erythrocyte membrane were investigated by ANTS/DPX leakage, membrane binding and fusion assay. (omitted)

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