DIRECT MODULATI6ON OF MAXI-K CHANNEL IN SMOOTH MUSCLE CELL

  • Lee, Moo-Yeol (Department of Physiology, College of Medicine, Chung-Ang University) ;
  • Chung, Sung-Kwon (Department of Physiology, College of Medicine, Chung-Ang University) ;
  • Bang, Hyo-Weon (Department of Physiology, College of Medicine, Chung-Ang University) ;
  • Uhm, Dae-Yong (Department of Physiology, College of Medicine, Chung-Ang University)
  • Published : 1996.07.01

Abstract

The activities of Maxi-K channels were recorded using inside-out patches. The application of 30 nM of non-specific G protein activator, GTP $\gamma$S, to the intracellular side of the channels increases the channel activities about 3-fold, indicating that there exist some G proteins within the patch membranes to regulate the channel activities. (omitted)

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