• Title/Summary/Keyword: zenorhabdins

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Unsual Cytotoxic Phenethylamides form Xenerhabdus nemetophilus

  • Baek, Seon Guk;Park, Yeong Hwan;Seo, Seung Il;Kim, Hyeon Su;Lee, In Seon;Park, Myeong Gwang;Lee, Cheon Su;Park, Seon Ho
    • Bulletin of the Korean Chemical Society
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    • v.22 no.4
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    • pp.372-374
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    • 2001
  • Three simple carboxamides incorporating the phenethylamine moiety have been isolated from strain XR-NC of a symbiotic bacterium Xenorhabdus nematophilus. Their structures were identified by spectroscopic data and synthesis. The compounds exhibited significant cytotoxicities against human cancer-cell line, viz. the gastric adenocarcinoma, colon adenocarcinoma and lung adenocarcinoma.