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Immunoglobulin G4-Related Disease in the Diaphragm: A Case Report (횡격막에 발생한 면역글로불린 G4 연관 질환: 증례 보고)

  • Jin Woo Kim;Taehwa Kim;Kun-Il Kim;Yeon Joo Jeong;Dohyung Kim;Dong Hoon Shin;Yun Seong Kim
    • Journal of the Korean Society of Radiology
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    • v.85 no.5
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    • pp.954-959
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    • 2024
  • Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated condition characterized by mass-forming inflammation with a sclerosing pattern that can affect nearly any organ. However, involvement of the diaphragm in IgG4-RD is exceptionally rare. We present the case of a 62-year-old male patient with chest radiographic abnormalities. Further investigation with CT revealed an infiltrative mass in the right hemidiaphragm. This mass, composed of engorged feeding vessels, an atypical manifestation of IgG4-RD, was also associated with lymphadenopathy. Surgical excision confirmed the presence of IgG4-positive cell infiltration, solidifying the diagnosis of IgG4-RD. Notably, the patient remained asymptomatic and did not require any treatment postoperatively. This case highlights the uncommon presentation of IgG4-RD as an infiltrative diaphragmatic mass.

Development of Prediction Model for XRD Mineral Composition Using Machine Learning (기계학습을 활용한 XRD 광물 조성 예측 모델 개발)

  • Park Sun Young;Lee Kyungbook;Choi Jiyoung;Park Ju Young
    • Korean Journal of Mineralogy and Petrology
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    • v.37 no.2
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    • pp.23-34
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    • 2024
  • It is essential to know the mineral composition of core samples to assess the possibility of gas hydrate (GH) in sediments. During the exploration of gas hydrates (GH), mineral composition values were obtained from each core sample collected in the Ulleung Basin using X-ray diffraction (XRD). Based on this data, machine learning was performed with 3100 input values representing XRD peak intensities and 12 output values representing mineral compositions. The 488 data points were divided into 307 training samples, 132 validation samples, and 49 test samples. The random forest (RF) algorithm was utilized to obtain results. The machine learning results, compared with expert-predicted mineral compositions, revealed a Mean Absolute Error (MAE) of 1.35%. To enhance the performance of the developed model, principal component analysis (PCA) was employed to extract the key features of XRD peaks, reducing the dimensionality of input data. Subsequent machine learning with the refined data resulted in a decreased MAE, reaching a maximum of 1.23%. Additionally, the efficiency of the learning process improved over time, as confirmed from a temporal perspective.

Physico-Chemical Properties of Aggregate By-Products as Artificial Soil Materials (골재 부산물의 용토재 활용을 위한 특성 분석)

  • Yang, Su-Chan;Jung, Yeong-Sang;Kim, Dong-Wook;Shim, Gyu-Seop
    • Korean Journal of Soil Science and Fertilizer
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    • v.40 no.5
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    • pp.418-428
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    • 2007
  • Physical and chemical properties of the aggregate by-products including sludge and crushed dust samples collected from the 21 private companies throughout the country were analyzed to evaluate possible usage of the by-products as artificial soil materials for plantation. The pH of the materials ranged from 8.0 to 11.0. The organic matter content was $2.85g\;kg^{-1}$, and the total nitrogen content and available phosphate content were low as 0.7 percents and $12.98mg\;kg^{-1}$, respectively. Exchangeable $Ca^{2+}$, $Mg^{2+}$, $K^+$, and $Na^+$ were 2.29, 0.47, 0.02 and $0.05cmol\;kg^{-1}$, respectively. Heavy metal contents were lower than the limits regulated by environmental law of Korea. Textural analysis showed that most of the materials were silt loam with low water holding capacity ranged from 0.67 to 7.41 percents, and with low hydraulic conductivity ranged from 0.4 to $2.8m\;s^{-1}$. Mineralogical analysis showed that the aggregate by product materials were mostly composed of silicate, alumina and ferric oxides except calcium oxide dominant materials derived from limestones. The primary minerals were quartz, feldspars and dolomites derived from granite and granitic gneiss materials. Some samples derived from limestone material showed calcite and graphite together with the above minerals. According to the result, it can be concluded that the materials could be used as the artificial soil material for plantation after proper improvement of the physico-chemical properties and fertility.

The Relationship of Age, Body Mass Index, and Individual Habit to Bone Mineral Density in Adults (성인의 연령, 체질량지수 및 생활습관과 골밀도의 관계)

  • Park, Soung-Ock;Lee, In-Ja;Shin, Gwi-Soon
    • Journal of radiological science and technology
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    • v.31 no.4
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    • pp.367-377
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    • 2008
  • We studied the change of bone mineral density (BMD) by age, body mass index (BMI), coffee, carbonated drink, alcohol, smoking, and exercise in adults who checked in health center. The number of study subjects was total 268 persons (women of 136 persons and men of 132 persons). The BMD was determined in lumbar spine and femoral neck by dual energy x-ray absorptiometry. And we got some results as below : 1. In women, mean body height was $155.8{\pm}6.0cm$, mean body weight was $56.8{\pm}7.9kg$, and mean BMI was $23.4{\pm}3.1kg/m^2$. In men, mean body height was $169.1{\pm}6.0cm$, mean body weight was $69.0{\pm}9.5kg$, and mean BMI was $24.1{\pm}2.7kg/m^2$. 2. BMD decreased as age increased, and the age was the most determinant factor for BMD (p<0.01). Women's BMD decreased rapidly in the groups aged $\geq$50s, while men's BMD decreased gradually with age. In addition, for both sex, lower BMD was measured in lumbar spine than in femoral neck. 3. BMD increased in high BMI, and BMD with BMI increased distinctly in the group aged 50s. But their relationship was not significant. 4. In view of the distribution by three BMD categories, women's BMD was mostly normal in the groups aged $\geq$40s, but the rate of osteopenia and osteoporosis was similar in the group aged 50s, and the rate of osteoporosis was the highest in the groups aged 60s and 70s. Men's BMD was mostly normal through all groups except the group aged 70s. 5. Coffee and carbonated drink were not influenced in BMD. But alcohol-drinking group showed higher BMD than non-drinking group, and alcohol was statistically significant determinant for BMD (p<0.05). Smoking and exercise were not statistically significant determinant of BMD.

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Evaluation of usability of the shielding effect for thyroid shield for peripheral dose during whole brain radiation therapy (전뇌 방사선 치료 시 갑상선 차폐체의 주변선량 차폐효과에 대한 유용성 평가)

  • Yang, Myung Sic;Cha, Seok Yong;Park, Ju Kyeong;Lee, Seung Hun;Kim, Yang Su;Lee, Sun Young
    • The Journal of Korean Society for Radiation Therapy
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    • v.26 no.2
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    • pp.265-272
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    • 2014
  • Purpose : To reduce the radiation dose to the thyroid that is affected to scattered radiation, the shield was used. And we evaluated the shielding effect for the thyroid during whole brain radiation therapy. Materials and Methods : To measure the dose of the thyroid, 300cGy were delivered to the phantom using a linear accelerator(Clinac iX VARIAN, USA.)in the way of the 6MV X-ray in bilateral. To measure the entrance surface dose of the thyroid, five glass dosimeters were placed in the 10th slice's surface of the phantom with a 1.5 cm interval. The average values were calculated by measured values in five times each, using bismuth shield, 0.5 mmPb shield, self-made 1.0 mmPb shield and unshield. In the same location, to measure the depth dose of the thyroid, five glass dosimeters were placed in the 10th slice by 2.5 cm depth of the phantom with a 1.5 cm interval. The average values were calculated by measured values in five times each, using bismuth shield, 0.5 mmPb shield, self-made 1.0 mmPb shield and unshield. Results : Entrance surface dose of the thyroid were respectively 44.89 mGy at the unshield, 36.03 mGy at the bismuth shield, 31.03 mGy at the 0.5 mmPb shield and 23.21 mGy at a self-made 1.0 mmPb shield. In addition, the depth dose of the thyroid were respectively 36.10 mGy at the unshield, 34.52 mGy at the bismuth shield, 32.28 mGy at the 0.5 mmPb shield and 25.50 mGy at a self-made 1.0 mmPb shield. Conclusion : The thyroid was affected by the secondary scattering dose and leakage dose outside of the radiation field during whole brain radiation therapy. When using a shield in the thyroid, the depth dose of thyroid showed 11~30% reduction effect and the surface dose of thyroid showed 20~48% reduction effect. Therefore, by using the thyroid shield, it is considered to effectively protect the thyroid and can perform the treatment.

An Experimental Method for the Scatter Correction of MV Images Using Scatter to Primary Ratios (SPRs) (산란선 대 일차선비(SPR)를 이용한 MV 영상의 산란 보정을 위한 실험적 방법)

  • Jeon, Hosang;Park, Dahl;Lee, Jayeong;Nam, Jiho;Kim, Wontaek;Ki, Yongkan;Kim, Donghyun;Lee, Ju Hye;Kim, Dongwon
    • Progress in Medical Physics
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    • v.25 no.3
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    • pp.143-150
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    • 2014
  • In general radiotherapy, mega-voltage (MV) x-ray images are widely used as the unique method to verify radio-therapeutic fields. But, the image quality of MV images is much lower than that of kilo-voltage x-ray images due to scatter interactions. Since 1990s, studies for the scatter correction have performed with digital-based MV imaging systems. In this study, a novel method for the scatter correction is suggested using scatter to primary ratio (SPR), instead of conventional methods such as digital image processing or scatter kernel calculations. We measured two MV images with and without a solid water phantom describing a patient body with given imaging conditions, and calculated un-attenuated ratios. Then, we obtained SPR distributions for the scatter correction. For experimental validation, a line-pair (LP) phantom using several Al bars and a clinical pelvis MV image was used. As the result, scatter signals of the LP phantom image were successfully reduced so that original density distribution of the phantom was restored. Moreover, image contrast values increased after SPR correction at all ROIs of the clinical image. The mean value of increases was 48%. The SPR correction method suggested in this study has high reliability because it is based on actually measured data. Also, this method can be easily adopted in clinics without additional cost. We expected that the SPR correction can be an effective method to improve the quality of MV image guided radiotherapy.

Effect of Hydration on Swelling Properties and Shear Strength Behavior of MgO-sand Mixture (수화 반응에 따른 MgO-모래 혼합물의 팽창 특성 및 전단 거동 변화)

  • Lee, Jihwan;Yoon, Boyoung;Choo, Hyunwook;Lee, Woojin;Lee, Changho
    • Journal of the Korean Geotechnical Society
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    • v.36 no.11
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    • pp.97-106
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    • 2020
  • Swelling properties and shear strength behavior of MgO-Sand mixtures with hydration procese of MgO are compared according to different MgO contents (WMgO/WTotal=0, 30, 50, 70, 100%) in this study. The specimens are prepared by mixing with crushed MgO refractory bricks and silica sand. After hydration, the particle size and the specific gravity of MgO were decreases. Through microstructure observation and X-ray diffraction analysis, it is confirmed that MgO changes from the cubic structure of Periclase to the hexagonal cubic structure of Brucite after hydration. As the MgO content increases, both swelling rate and swelling pressure of the mixtures increase. WMgO/WTotal=30% specimen shows relatively low swelling pressure and swelling rate because produced Mg(OH)2 mainly fills the pores between sand particles. However, in the case of MgO more than 50%, swelling pressure and swelling rate increase significantly because Mg(OH)2 fills the pores of sand particles at first and then either pushes out sand particles or Mg(OH)2 particles after filling the pores. As a result of the direct shear test, before hydration, the mixtures show a dilative behavior on high MgO contents and a contractive behavior on low MgO contents. However, after hydration, the behavior of all mixtures changes to contractive behavior. The threshold fraction of fine (i.e., Mg(OH)2) contents of the hydrated MgO-Sand mixtures reveals approximately 60% compared with normalized shear strength.

Surface Analysis Study on ZIRLO Cladding Hulls Oxidized at Low Temperatures (저온 산화된 ZIRLO 피복관의 표면분석 연구)

  • Jeon, Min Ku;Choi, Yong Taek;Lee, Chang Hwa;Kang, Kweon Ho;Park, Geun Il
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.12 no.3
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    • pp.235-243
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    • 2014
  • Surface oxidation behavior of ZIRLO (ZIRconium Low Oxidation) hulls was investigated using an X-ray photoelectron spectroscopy (XPS) technique. The effects of oxidation time (10-336 h at $500^{\circ}C$) and temperature ($400-700^{\circ}C$ for 10 h) were studied. Deconvolution results of the hulls oxidized at $500^{\circ}C$ revealed that a $ZrO_2$ phase appeared after 24 h (11.86%), and an increase in the $ZrO_2$ ratio was observed when the hulls were oxidized for 336 h (17.93%). On the other hand, the ZrO phase which employed 5.68% in the 10 h oxidized sample disappeared when the oxidation time increased to 24 h. The XPS results also showed that an increase in the oxidation temperature resulted in an increase in the ratio of ZrO, which increased from 0 to 5.68, 8.31, and 9.16% when the oxidation temperature increased from 400 to 500, 600, and $700^{\circ}C$, respectively. $ZrO_2$ phase was observed only in the sample that was oxidized at $700^{\circ}C$. The mechanism of ZrO formation was not conclusive, but it was suggested that a formation of hydroxide might have been accelerated at elevated temperatures leading to a formation of a $Zr(OH)_4$ phase. The relationship between the surface oxidation status of the hulls oxidized at $500^{\circ}C$ and their chlorination reaction feasibility was discussed, and it was suggested that the thickness of the oxide layer is an important parameter that determines the chlorination reaction feasibility.

Effects of Magnesium and Sulfate Ions on the Sulfate Attack Resistance of Alkali-activated Materials (알칼리 활성화 결합재 모르타르의 황산염 침식 저항성에 미치는 마그네슘 및 황산 이온의 영향)

  • Park, Kwang-Min;Cho, Young-Keun;Shin, Dong-Cheol
    • Journal of the Korea Concrete Institute
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    • v.29 no.4
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    • pp.415-424
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    • 2017
  • The purpose of this study is to investigate the effect of sulfate (${SO_4}^{2-}$) and magnesium ($Mg^{2+}$) ions on sulfate resistance of Alkali-activated materials using Fly ash and Ground granulated blast furnace slag (GGBFS). In this research, 30%, 50% and 100% of GGBFS was replaced by sodium silicate modules ($Ms(SiO_2/Na_2O)$, molar ratio, 1.0, 1.5 and 2.0). In order to investigate the effects of $Mg^{2+}$ and ${SO_4}^{2-}$, compression strength, weight change, lengh expansion of the samples were measured in 10% sodium sulfate ($Na_2SO_4$), 10%, 5% and 2.5% magnesium sulfate ($MgSO_4$), 10% magnesium nitrate ($Mg(NO_3)_2$), 10% [magnesium chloride ($MgCl_2$) + sodium sulfate ($Na_2SO_4$)] and 10% [magnesium nitrate $(Mg(NO_3)_2$ + sodium sulfate ($Na_2SO_4$)] solution, respectively and X-ray diffraction analysis was conducted after each experiment. As a result, when $Mg^{2+}$ and ${SO_4}^{2-}$ coexist, degradation of compressive strength and expansion of the sample were caused by sulfate erosion. It was found that the reaction of $Mg^{2+}$ with Calcium Silicate Hydrate (C-S-H) occurred and $Ca^{2+}$ was produced. Then the Gypsum ($CaSO_4{\cdot}2H_2O$) was formed due to reaction between $Ca^{2+}$ and ${SO_4}^{2-}$, and also Magnesium hydroxide ($Mg(OH)_2$, Brucite) was produced by the reaction between $Mg^{2+}$ and $OH^-$.

Changes of Radiation Dose and Image Quality Due to Additional Filtration Material in Computed Radiography (Computed Radiography에서 Additional Filtration Material에 따른 Radiation Dose와 Image Quality의 변화)

  • Kwon, Soon-Mu;Cho, Hyung-Wook;Kang, Yeong-Han;Kim, Boo-Soon;Kim, Jung-Su
    • Journal of radiological science and technology
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    • v.37 no.4
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    • pp.239-246
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    • 2014
  • Filter absorbs low-energy X-ray to increase the average energy and reduces patient exposure dose. This study investigates if the materials of Mo and W could be used for the digital imaging device CR by conducting image assessment and dose measurement of SNR, FOM and histogram. In addition, measurement of beam quality was conducted depending on the material of the filter, and at the same time, a proper combination of filters was examined depending on the change in tube voltage (kVp). In regard to entrance skin dose, Mo filter showed the dose reduction by 42~56%, compared to Cu filter. Moreover, Mo filter showed higher transmission dose by around 1.5 times than that of Cu filter. In image assessment, it was found that W was unsuitable to be used as a filter, whereas Mo could be used as a filter to reduce dose without decline in image quality at the tube voltage of 80 kVp or higher. As tube voltage increased, 2.0 mm Al+0.1 mm Mo almost had a similar histogram width to that of 2.0 mm Al+0.2 mm Cu. Therefore, Mo filter can be used at relatively high tube voltage of 80 kVp, 100 kVp and 120 kVp. The SNR of 2.0 mm Al+0.1 mm Mo did not show any significant difference from those of 2.0 mm Al+0.2 mm Cu and 2.0 mm Al+0.1 mm Cu. As a result, if Mo filter is used to replace Cu filter in general radiography, where 80 kVp or higher is used for digital radiation image, patient exposure dose can be reduced significantly without decline in image quality, compared to Cu filter. Therefore, it is believed that Mo filter can be applied to chest X-ray and high tube voltage X-ray in actual clinical practice.