Park Byeong Deog;Youm Jong Kyung;Ahn Sung Ku;Lee Seung Hun
Journal of the Society of Cosmetic Scientists of Korea
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v.30
no.3
s.47
/
pp.345-352
/
2004
There are two paradigms to explain the atopic dermatitis. The first is outside-inside paradigm and the second is inside-outside paradigm. According to the outside-inside paradigm the best way to treat the atopic dermatitis is recovery of skin barrier function. The barrier function is maintained by the specific structure of stratum corneum, which is constructed from corneocytes and intercellular lipids. In terms of lipid structures of SC in atopic dermatitis and lamellar ichthyosis, they contain more fluid hexagonal gel structures in SC and show deficiencies in free fatty acids, especially long chains and certain ceramides. With this reason, moisturizer which has the lamellar structure and restoring function of intrinsic intercellualr long periodicity phase can maintain and restore the lamellar structure of intercellular lipids in SC. The moisturizers containing ceramide or pseudoceramide also seem to be reasonable therapy for atopic dermatitis and several skin diseases, which interrelated with impaired skin harrier. By the way, according to the inside-outside paradigm, immune response including helper T cells, IgE, eosinophils is related. It is effective treatment of atopic dermititis to restore imbalance between Th1 and Th2 cells. Even though several kinds of immune-suppressor were introduced, these can affect the intrinsic immune function. SPC and S1P, metabolites of ceramide, would be interesting because they have the function of wound healing and immune modulating properties.
Kim, Won-Kyung;Kim, Kyoung-Hwa;Kim, Jong-Jin;Lee, Young-Kyu;Ku, Young
Journal of Periodontal and Implant Science
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v.35
no.2
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pp.345-357
/
2005
Prostaglandin plays a significant role in the local control of bone metabolism associated with periodontal disease. ${\Delta}^{12}-PGJ_2$ is a natural $PGD_2$ metabolite that is formed in vivo in the presence of plasma. It is known for ${\Delta}^{12}-PGJ_2$ to stimulate calcification in osteoblastic cells. Bone morphogenetic protein(BMP) stimulated osteoblastic differentiation in various types of cells and greatly enhanced healing of bony defects. The purpose of this study was to evaluate the effect of rhEMP-2 on ${\Delta}^{12}-PGJ_2$ induced osteoblastic differentiation and mineralization in vitro. A human osteosarcoma cells line Saos-2 were cultured. In the test groups, 10-7M of ${\Delta}^{12}-PGJ_2$ or mixture of 10-8M of ${\Delta}^{12}-PGJ_2$ and 100ng/ml of rhBMP-2 or 100ng/ml of rhEMP-2 were added to culture media. After 1 day, 2 days and 4 days of culture period, the cell number was measured. Alkaline phosphatase activity was measure at 3 days. Reverse transcription polymerase chain reaction(RT-PCR) was performed to determine the expression of mRNA of bone matrix protein at 8 hours, 1 day and 7 days. The ability to produce mineralized nodules in rat osteoblasts(MC3T3-E1) was evaluated at 21 days. The results were as follows : 1. rhEMP-2 or mixture of rhBMP-2 and ${\Delta}^{12}-PGJ_2$ inhibited cell proliferation of human osteosarcoma cells. 2. rhEMP-2 or mixture of rhBMP-2 and ${\Delta}^{12}-PGJ_2$ stimulated alkaline phosphatase activity significantly higher than ${\Delta}^{12}-PGJ_2$ alone. 3. rhBMP-2 or mixture of rhEMP-2 and ${\Delta}^{12}-PGJ_2$ stimulated mineralization compared to ${\Delta}^{12}-PGJ_2$ alone. 4. mRNA of alkaline phosphatase, BMP-2, cbfa 1, Type I collagen were detected in the group treated with ${\Delta}^{12}-PGJ_2$/rhBMP-2, rhBMP-2 alone, ${\Delta}^{12}-PGJ_2$ alone. These results show that mixture of ${\Delta}^{12}-PGJ_2$ and rhBMP-2 causes more bone formation than ${\Delta}^{12}-PGJ_2$ alone while the bone formation effects of mixture of ${\Delta}^{12}-PGJ_2$ and rhBMP-2 are less than those of rhBMP-2 alone. Further researches would be necessary to clarify the interactions of these agents.
The Gubong gold-silver deposits if gold-silver-bearing hydrothermal massive quartz veins which were filled the fractures along fault shear (NE, NW) zones within Precambrian banded or granitic gneiss of Gyeonggi massif. Ore mineralization of this deposits is contained within a single stage of quartz vein which was formed by multiple episodes of fracturing and healing. Ore minerals are comported mainly of arsenopyrite, pyrite, sphalerite, chalcopyrite, galena with minor amounts of pyrrhotite, marcasite and electrum. The frequency and volume percentages of electrum associated with ore minerals from this deposits are recognized as follows; 44.5% and 54.3% with arsenopyrite, 24.3% and 33.8% with quartz, 12.6% and 0.1% with pyrite, 11.0% and 4.8% with galena, 5.0% and 7.0% with sphalerite and 2.5% and 0.02% with chalcopyrite, respectively. They show irregular (41.6%), subround (34.7%), elongate (17.0%) and granular (6.6%) shapes, respectively. Their grain size ranges from 2 to 150 um, but 90.9 percent of the grains are below 30 um. The chemical composition of electrums ranges from 26.39 to 72.51 Au atomic %. These composition (Au atomic %) on the basis of associated minerals are from 44.97 to 71.75 with arsenopyrite, pyrite, sphalerite and quartz, from 44.37 to 72.51 with quartz, from 35.40 to 41.01 with sphalerite and chalcopyrite, from 26.39 to 54.84 with pyrite, chalcopyrite, quartz and galena, from 28.49 to 53.28 with galena, respectively. We suggest that optimum recovery of gold would be obtained with reference to these results.
Purpose : This study aims to suggest social support composed of organizational support and managerial support would be systematically managed to enhance Disaster Operations Management at Seoul Emergency Operations Center. Method : Emotional labor was used as an independent variable, and organizational commitment was used as a dependent variable to analyze the mediating effects of social support. Results : First, in the aspect of organizational support, the objective evaluation of disaster situation management, disaster situation management emotional labor reduction education and training program development, monitoring of disaster situation management, quality improvement and work imbalance mitigation of firefighters, and emergency coordination managers are needed for systematic work management for emotional labor settlement. Secondly, it is necessary to select competent firefighters in the level of managerial support, to prepare healing measures for structured phased emotional labor for firefighters, and to have counseling competency for managers for emotional labor firefighting officers. Conclusion : In order to improve disaster management ability, education and training programs should be developed to improve organizational commitment based on social support.
The Journal of the Korean Institute of Forest Recreation
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v.22
no.4
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pp.23-33
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2018
The purpose of this research is to develop basic materials useful for the visiting management policies' establishment of national parks by analyzing the characteristics of and satisfaction with the visit to Hallyeohaesang National Park according to travel routes. For this, a total of 671 visitors to Hallyeohaesang National Park were recruited and field surveys were conducted three times in spring, summer, and fall from March to November 2017. The Hallyeohaesang national park's visitors were surveyed using a self-administered questionnaire about visitor characteristics (ex: motivation of visiting, travel routes, travel time, and participating activities, etc.) and satisfaction (ex: satisfaction with the visit, intention to revisit, and intention to recommend). SPSS 21.0 program was used for the statistical analysis: frequency analysis and independent-samples t-test analysis. As a result of analysis the motivation of visiting, those who visited only Hallyeohaesang National Park (a single destination) showed a mean value statistically significantly higher level in health improvement and vacation, relaxation, and healing compared to those who had visited or would visit other places along with Hallyeohaesang National Park (multi-destinations). Single destination visitors spent less time traveling from home to national park than multi-destinations visitors. Those who visited only Hallyeohaesang National Park (as a single destination) showed a mean value statistically higher satisfaction and intention to revisit and recommend. The results of this research have significance in providing basic materials to develop efficient park management policies by studying the characteristics of Hallyeohaesang National Park visitors.
In Daesoon Jinrihoe, the Supreme God descended into the mortal world by incarnating as Kang Jeungsan to save the world from imminent disaster. Daesoon Jinrihoe is regarded by some Chinese scholars as a new Korean Daoism, and Jo Jeong-san, the Lord of the Dao in Daesoon Jinrihoe, revealed the Supreme God's name to "Gucheon Eungwon Noeseong Bohwa Cheonjon Kangseong Sangje." Comparative studies are often conducted to highlight the similarities between this god and the nearly identically named god in Chinese Daoism. However, this Chinese god is only a god of natural phenomena and has no previous connections to descension into the world via human incarnation. My research has determined that the closest basis for comparison would be Emperor Huizong within the context of Northern Song Dynasty Daoism. In the Daoism of that time period, he was understood to be the Supreme God who incarnated as a human to save the world. Borrowing Eliade's Phenomenology of Religion, this paper has discovered that core archetypes of these two godheads are different due to their different soteriological missions. In order to solve the grievances among humans, divine beings, heaven, and the afterworld, Kang Jeungsan actualized the Earthly Paradise of Later World. Drawing on the archetypal notion of an Original Time, he reshaped the world into the beginning of chaos to completely eliminate the past, and to create a fundamentally and qualitatively new era. On the other hand, Emperor Huizong tried to absorb what he viewed as heretical Buddhism into something sacred that could be used to save people from its harm. He established a hierarchy radiating from the archetypal notion of the Center of the Universe, and he cosmosized Buddhism, which he viewed as barbaric, into that order. Their core godheads mainly show differences in terms of time and space. Additionally, their extended sub-godhead symbols are quite different. Emperor Huizong, like the common supreme gods of other religions, established law of order, and then retreated as the symbol of heaven, the abdicated god. His divine power was specialized as Lin Lingsu's symbol of natural phenomena. Kang Jeungsan was completely different. He always proved his power over the three realms through different symbols. The main symbols he used were the moon for healing and resurrection, water for establishing order from chaos, and light for enabling secular individuals to experience sacred profundity.
Jeong, Na Ra;Kim, Kwang Jin;Yoon, Ji Hye;Han, Seung Won;You, Soojin
Journal of People, Plants, and Environment
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v.23
no.6
/
pp.603-614
/
2020
Background and objective: This study was conducted to understand urban residents' perception of indoor plants in order to assist in the preparation of guidelines for growing plants indoors. Methods: Questionnaires were distributed to urban residents currently growing plants or with experience of growing plants. The data of 247 respondents were subjected to analysis to assess their level of interest and ability with regard to growing plants, and their recognition of the selection and function of plants. Results: Respondents showed high interest in growing plants at a level of 6.77, but their ability was moderate. This suggests that information regarding plant maintenance should be provided to urban residents. They recognized the function of plants for improving the environment as important, and expected that indoor plants would improve their mood and visual experience. Satisfaction with growing plants was high from an emotional perspective. They recognized that the function of air purification function was important even if the actual performance or effect was not great. This indicates that the function of air purification should be emphasized more. As the result of the IPA, plants should be selected in consideration of morphological characteristics such as leaf, flower and fruit, and continuously managed to maintain their characteristics. Since the performance of pots was less satisfactory compared to their importance, they should be selected so that they harmonize better with plants and are of the appropriate size to fit the space. The type of plants is an important factor in plant selection in order to perform an environmental function, and the flower color and pot size are important in terms of aesthetics and healing. Conclusion: When horticulture information on indoor plants is provided to urban residents, first, it should be provided to satisfy the functions of the plants required by urban residents and in order to promote and maintain the proper growth of plants. Second, various contents that utilize components should be developed to achieve plant function so that resident can determine the function of plants and select the type, quantity, and shape of plants to achieve the desired function.
The number of Frida Kahlo's works is 143, 55 of which are her own portraits. She spent a great deal of time on the production of her works, a large portion of which is taken up by her portraits. Art and creation by artist are the expressive process of artist's unconsciousness. Certain works express personal unconsciousness and collective, archetypal unconsciousness. These works evoke certain impressive image or unknown emotion in their mind impulsively. Artist could talk with their own work in this process. The producted symbolic images want to seek harmony with the artist's consciousness. This study has examined, from the viewpoint of analytical psychology, the psychological changes of Frida Kahlo by way of interpreting 4 of her own realistic portraits. These particular 4 works were finished in the most critical life time of Frida Kalho. We tried to find out what the purpose of her work would be. From the examination the following characteristics were gound. 1) Her portraits are not only concerned with her personal life and personal unconscious, but they also contain elements of the collective unconscious. 2) She experienced a psychological healing for herself in the process of transforming shocking events into painful portraits. 3) Her self portraits are the expression of the creative transformation she underwent.
The purpose of this study is to provide a reference for the development of forest therapy programs for subfertile women. This exploratory study identifies the emotional characteristics of subfertile women and the demands for forest therapy according to the emotional characteristics and provides basic data for the development and operation of forest therapy programs. This study surveyed 200 subfertile women who visited a subfertility hospital in Seoul on 33 items of subfertile women's emotional characteristics and requirements of forest therapy programs. We conducted the frequency analysis, cross-analysis, and one-way ANOVA to determine the correlation and importance between the emotional characteristics of subfertile women and the demands for forest therapy programs using the SPSS 21.0 program. Emotional traits of subfertile women included pressure on pregnancy, anxiety/fear, depression, hopelessness, helplessness, loneliness, sadness, shame/guilt, impatience/frustration, and anger/hypersensitivity. Of these traits, pressure on pregnancy, depression, hopelessness, helplessness, loneliness, sadness, anger/hypersensitivity, and anxiety/fear were particularly high among subfertile women. The demands for forest therapy programs also differed according to the emotional characteristics of subfertile women. There was a significant difference in the operation mode of the subfertile couple's forest therapy program according to the pressure, shame, and guilt of pregnancy. There was a significant difference in the experience of participating in a program according to anxiety and fear and in the reason for not being able to participate in the forest therapy program according to depression, hopelessness, helplessness, loneliness, and sadness. There was a significant difference in couples participating the in the forest therapy program according to impatience and frustration. There was a significant difference in the experience of participating in the forest therapy program and the effect of self-help groups through the forest therapy program for subfertile women according to anger and hypersensitivity. We expect that the results of this study would be useful as the reference data for developing forest therapy programs for the improvement of the mental health of subfertile women.
The purpose of this study was to make and ascertain a decision making process on the base of patient-oriented utilitarianism in the treatment of patients of chronic adult periodontitis. Fifty subjects were chosen in Yonsei Dental hospital and the other fifty were chosen in Severance dental hospital according to the selection criteria. Fifty four patients agreed in this study. NS group(N=32) was treated with scaling and root planing without any surgical intervention, the other S group(N=22) done with flap operation. During the active treatment and healing time, all patients of both groups were educated about the importance of oral hygiene and controlled every visit to the hospital. When periodontal treatment needed according to the diagnostic results, some patients were subjected to professional tooth cleaning and scaling once every 3 months according to an individually designed oral hygienic protocol. Probing depth was recorded on baseline and 18 months after treatments. A questionnaire composed of 6 kinds(hygienic easiness, hypersensitivity, post treatment comfort, complication, functional comfort, compliance) of questions was delivered to each patient to obtain the subjective evaluation regarding the results of therapy. The decision tree for the treatment of adult periodontal disease was made on the result of 2 kinds of periodontal treatment and patient's ubjective evaluation. The optimal path was calculated by using the success rate of the results as the probability and utility according to relative value and the economic value in the insurance system. The success rate to achieve the diagnostic goal of periodontal treatment as the remaining pocket depth less than 3mm and without BOP was $0.83{\pm}0.12$ by non surgical treatment and $0.82{\pm}0.14$ by surgical treatment without any statistically significant difference. The moderate success rate of more than 4mm probing pocket depth were 0.17 together. The utilities of non-surgical treatment results were 100 for a result with less than 3mm probing pocket depth, 80 for the other results with more than 4mm probing pocket depth, 0 for the extraction. Those of surgical treatment results were the same except 75 for the results with more than 4mm. The pooling results of subjective evaluation by using a questionnaire were 60% for satisfaction level and 40% for no satisfaction level in the patient group receiving nonsurgical treatment and 33% and 67% in the other group receiving surgical treatment. The utilities for 4 satisfaction levels were 100, 75, 60, 50 on the base of that the patient would express the satisfaction level with normal distribution. The optimal path of periodontal treatment was rolled back by timing the utility on terminal node and the success rate, the distributed ratio of patient's satisfaction level. Both results of the calculation was non surgical treatment. Therefore, it can be said that non-surgical treatment may be the optimal path for this decision tree of treatment protocol if the goal of the periodontal treatment is to achieve the remaining probing pocket depth of less than 3mm for adult chronic periodontitis and if the utilitarian philosophy to maximise the expected utility for the patients is advocated.
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