항-N-methyl-D-aspartate 수용체 뇌염(Anti-NMDAR encephalitis)은 NMDA 수용체에 대한 자가항체로 매개되는 신경 염증성 질환으로 초기에 뚜렷한 신경학 증상 없이 망상, 지각이상, 와해된 행동, 심한 불안, 인지기능저하 등의 정신증상이 두드러질 수 있다. 면역치료 혹은 종양제거와 같은 조기치료가 좋은 예후 인자이므로 질병초기에 정신질환과 구분하여 항-NMDAR 뇌염을 진단하는 것이 중요하다. 본 증례에서는 간질과 정신병적 증상을 보이는 26세 여성 A씨를 조기에 항-NMDAR 뇌염으로 확진한 뒤 양성 및 음성증상 척도(Positive and Negative Syndrome Scale, PANSS)를 사용하여 평가하였다. A씨의 항-NMDAR 뇌염 초기의 정신증상으로 PANSS에서 양성하위척도 보다 음성하위척도 점수가 더 높았다. 정신장애와 비교하여 항-NMDAR 뇌염 초기에 음성증상과 인지장애가 더욱 두드러질 가능성이 있다. A씨의 치료로는 rituximab과 난소 기형종의 제거가 효과적이었고 항정신병제로는 quetiapine을 사용하였다. 특히 젊은 여성에서 망상, 행동장애와 함께 음성증상, 인지장애, 긴장증, 의식수준의 변화, 운동이상증상 등이 관찰될 때 항-NMDAR 뇌염에 대한 평가를 고려해야 한다.
Objectives : Epidemiological studies in other countries show that a low intake of omega-3 fatty acids (FAs) increases the risk of depression or suicidality. However, no studies have investigated the associations of suicidality with omega-3 FAs in Korea. Hence, this cross-sectional study aimed to investigate the effects of omega FAs on suicidality in the general South Korean population. Methods : The data in this study were sourced from adults (n=215,860) who completed the Sixth Korea National Health and Nutrition Examination Survey (KNHANES VI), and the associations between omega FAs and suicidality were analyzed using multivariate logistic regressions. Results : Our results demonstrated that high omega-3 FA intake was associated with a decreased risk of suicide (OR=0.83, 95% CI : 0.71-0.98) and the high omega-6 to omega-3 FA ratio was associated with an increased risk of suicide (OR=1.25, 95% CI : 1.02-1.54). Additionally, a high intake of omega-3 FAs was associated with a decreased risk of suicide in men, but not in women (OR=0.72, 95% CI : 0.59-0.88). Conclusions : Overall, our findings suggest that a lower intake of omega-3 FA is associated with the increased risk of suicidality in the general Korean population, especially in men.
Objectives: The purpose of this study was to examined the association between unemployment and suicidal ideation in Korea. Methods: We analyzed data from the Korean National Health and Nutrition Examination Surveys (KNHANES) IV, conducted in 2009. Statistical analysis methods used in this study were $x^2$-test, Hierarchial logistic regression analysis and other basic statistics using SPSS version 19.0. Results: The suicidal ideation of unemployment workers was 24.7% in male and 35.9% in female. After adjusting for sociodemographic characteristics and health-related characteristics, the risk for suicidal ideation of unemployment workers was significantly higher than employment workers. In men, the OR for suicidal ideation of the employed workers compared with the employed was 2.13, and in women, the OR was 1.31. Conclusions: The findings suggest the impact of unemployment status on suicidal ideation and the need for further prospective investigation that lead to interventions should be required to introduce of suicide prevention program for unemployment worker.
This study was performed to investigate the nutritional status of neurosurgical tube-fed patients. The objective of this study was to improve the nutrition management of tube-fed patients. The current practices of tube feeding and enteral nutrition formula as for 95 patients in the hospital were examined by reviewing patients charts, and interviewing patients, nurses and their family members. The results are summarized as follows ; 57.9% of patients that received the formula showed a decrease in mental status. Among the subjects, 55.7% had nervous system diseases due to old age. Most of the tube-fed patients were hospitalized in the emergency room and while hospitalized, the status of their respiratory organ was abnormal. The method of tube-feeding was by Bolus injection and the type of the tube was a 16Fr size silicone tube. The amount of the injection per day while tube-feeding was on average 1424kcal for men and 1322kcal for women and the calories per day ranged from 1000-1500kcal(50.5%). The injection volume averaged 332.7ml and 45% of patients received more than 300ml per injection. The tube feeding intake rate was 127.9ml/min with 50% of subjects in the range of 50-100ml/min and 10% at 20ml/min. The longer the hospitalization, the older age, coma status, and the higher tube feeding rate, the more decreased were the biochemical parameters.
Background: The purpose of this study was to find out the effects of the hand movement exercise program on the cognitive function of the older with dementia. Methods: A total of twenty-four subjects were divided into two research groups and one control group, respectively. Each exercise was conducted in twelve weeks: three times a week, twice a day for fifteen minutes. Enhancement of cognitive function in each exercise program was evaluated four times using MMSE-KC, the Korean version of the Mini-Mental State. Results: As for enhancement of cognitive function, the hand movement exercise program represented an increase of $1.63{\pm}.92$ over those before study, showing significant differences (p<.05); the large muscle exercise program, $.75{\pm}.89$; and the activities of daily living program, $.00{\pm}2.14$, showing no significant differences. Conclusion: Hand Movement Exercise Program can be inferred from the results that consistent exercise program is more effective than any other ways for enhancement of cognitive function of the older with dementia.
Background: The elderly are likely to fall due to physical and mental atrophies, and experiencing falls may result in fear of falls and lack of self-confidence, which also leads to hesitation to physical activities and changes in walk and balance, the major variables in independent daily life. Methods: In three senior citizen centers located in D city, 22 elderly women aged 65 or older were chosen, and they filled in the questionnaire which included their agreement to voluntarily participate in the survey and medical histories. As to whether they had falls experience, the medical history items in the questionnaire asked them if they had falling down or falls once a year, twice for the three years. The objects were divided to NFE (non-falls experience) and FE (falls experience). Results: 1. As to walking abilities, significant difference was found between NFE and FE regarding walk width, stepping with two feet, and stride length while there was no significant different in terms of cadence. 2. As to balancing abilities, was significant difference between NFE and FE in terms of the physical body center area. As to the sit-to-stand, tandom gait test, no significant difference was found, and neither in the timed up and go test. Conclusions: The elderly with falls experience has inferior walking and balancing abilities to those without falls experience, and thus they are more exposed to the risks of falls.
This study attempted to identify important problems of the factors related to the indwelling catheter with closed drainage and to enhance recognization of Urinary Tract Infection management to protect patients with indwelling catheter from UTI. We selected the 58 patients with indwelling catheter with closed drainage from md-surg. intensive care units, and general neurological and neurosurgical ward, in one hospital in Pusan, Korea from May 30 to October 15, 1993. Patients were examined by urinary analysis before inserting catheter and then by urine cultures three times. The obtained data was analized using an SPSS /PC$^{+}$ The statistical analyses employed here was the frequency, percentage and x$^2$-tests. 1. Analyses for Indwelling Catheter induced UTI and infection rates were found to be presented in patients related to the factors of being on antibiotic drugs (x$^2$=14.105, p=.000) and the duration of the indwelling catheter(x$^2$=58.0, p=.000), both of which were found to affect the UTI. 2. UTI rates according to the duration of the in-dwelling catheter were high 8.6% for the 2nd day, 27.6 for the 4th day, and 36.2% for the 7th day, and as the duration for the indwelling catheter was longer, UTI rates were higher. 3. The UTI rates according to the duration of the indwelling catheter related re factors, on the 7th day, were high-52.0% for women, 37.0% for more than 50 years in ages, 30.0% for patients under sur-gery, 33.3% for altered mental states outsides the alert, 76.7% for patients not given antibiotic drugs, 36.4% for less than 3500cc of fluids intakes, it was found that these affected to increase the UTI. 4. Causative organisms of UTI were found ; E.Coli appears the most than all other isolated organisms in women and Klebsiella and Pseudomonas in men. For antibiotic susceptibility of causative organisms, all causative organisms were found to be susceptible to Sul -cefoperazone, Trim-prim, and unasyn and Pseudomonas mostly net susceptible.e.
The purpose of this study is to examine a married nurse's experience of child rearing through being applied to phenomenological research method. By exchanging their experiences, helping and understanding one another, married nurses can work with delight considering their own present job as their lifelong job. In addition this study can help single nurses overcome the female crises such as marriage, childbirth, and child rearing they will experience in the future. The subjects of this research was 26 married nurses who work for a university hospital in affiliation in Seoul and have children. The period of materials collection was from Feb. 1st to Mar. 3, 1995. The method of materials collection was primarily to write down a questionary with openhearted contents. In collecting it, the respondents were allowed to say at their pleasure through further interview. The materials were analyzed by Giorgi's phenomenological analysis method. The findings of this study are as follows ; 1) The responses of married nurses' experience of child rearing-[pleasure] [family solidarity] [maternal-infant attachment] [understanding] [toilsome]-were induced. That is, at once affirmative experience and hard experience coexisted. 2) The method of married nurses' child rearing-[rearing politely] [raising understanding] [having the sense of family community] [rearing with praying the heart] [careless]-were induced. 3) The support system of married nurses' child rearing-[having help family] [having help from others]-were induced. According to the above findings, the married nursed showed affirmative responses about their experience of child rearing, but at the same time they expressed painful when stayed apart from their children on account of their job or when their children were sick. In the method of child rearing, they tried to grow their children polite because there was much time for them to stay apart from their children. And they tried to give a better explanation in order that their children can have an independence spirit. They tended to compensate through frequent physical touch with their children. As the support system of married nurses' child rearing, they asked their parents or their parents-in-law to take care of their children, hired a nursery governess in their houses, or used a children's home, if they can't afford to. That is, the only one who has a firm sense of her profession, tries to inspire her accomplishment, and is receiving her husband' love and understanding is considered to perform two things simultaneously with harmony, having an recognition of lifelong job. Suggestions 1. The method to solve mental troubles on child rearing should be groped. 2. Their economical burden should be reduced by establishing children's home in their working places, and the increase of maternal-infant interaction should be contrived. 3. The chance of education should be offered in order that married nurses themselves might inspire self-conceit and professionalism on clinical nursing. 4. The familiar mood should be created through planning the programs to be accompanied with children as an annual event in hospital. 5. The part-time nurse system should be suggested to utilize. 6. The system of circulation working should be converted into the system of fixing working according to the characteristic of each department. 7. Programs for special activities such as learning foreign languages and computer should be supported positively.
Obesity is chronic disease which influenced on health severly. The causes of obesity have been known as life change, lack of excercise, genetic factor, mental and social economic factors. Especially the obesity of women increased the risk of the diseases such as DM, osteoarthritis, cardiovascular disease, breast cancer and infertility. The limitations of the widely used negative definition of health as the absence of disease and WHO's 1946 definition of health as total social, psychological and physical well-being have long been recognized (WHO 1958). The Quality of Life (QoL) includes functional ability, the degree and quality of social and community interaction, psychological well-being as somatic sensation and life satisfaction. I investigated to compare the differences between obese women (n=63), non-obese women (n=37) in clinic and general women (n=43, control) on baseline characteristics and WHO QoL-BREF. The purpose of this study is to assist the diagnosis and treatment of obesity. WHO QoL-BREF is self administered type which consisted of 26 questions. The prospective question is calculated with 5 scores by Likert's method. The results are as follows : The means of physical, psychological, social, overall and total scores of QoL were significant among BMI group (P<0.05). The score of control group (BMI < 25) was higher than other groups significantly (P<0.05). In multiple regression analysis, the variable of high school/below middle school was significant in environmental and overall domain of QoL scores (P<0.05). The variable of college/below middle school was significant in environmental, overall domain and total score of QoL scores (P<0.05). The variable of above university/below middle school was significant in physical health, environmental, overall domain and total score in QoL scores (P<0.05). The variable of Health perception (moderate/bad) was positively significant in physical health, environmental, overall domain and total score of QoL scores (P<0.05). The variable of Health perception (good/bed) was positively significant in physical health, environmental, social, overall domain and total score of QoL scores (P<0.05). The variable as BMI non-=obese women/control was negatively significant in social domain of QoL scores (P<0.05). Above the results, It suggests that the variable as BMI did't affect on the QoL in patients and control, but the variables as education and health perception affected on the QoL scores. Further study is required to conduct QoL differences between before and after treatment of obese patients.
This study aimed at examining participation rate in taking health examinations. abnormal findings. and recognition and responses for re-examination recommendation among junior students at a university. Data were collected by interviews and self-reports between March and April. 2000. five months after receiving findings of health examinations. Question items in the questionnaire were made by the researchers. Participation rate for the health examination was $22.5\%$ of all registered junior students: $25.4\%$ for men and $16.6\%$ for women. College of medicine ranked the first in the participation rate. Of the examinees. $22.8\%$ showed abnormal findings. Of those students with abnormal findings. 149 students who were registered at the time of data collection became the subjects of the present study. The average age of the subjects was 23.7 years. The proportion of those with very good or. good self-evaluated physical health was $24.1\%$. while the proportion for mental health was $55.1\%$. The most prevalent problem for men was liver problem and for women anemia. More than $92\%$ of the subjects were aware of their abnormal findings. Those who sought advice were $71.8\%$ and their parents were most frequently asked for advice. As for the contents. $33.7\%$ were advised to visit a hospital. Of the 65 students recommended for re-examination. $60.9\%$ with liver problems took re-examination. while $37.2\%$ with urine problems. The multiple responses of the reasons for not following the recommendation for re-examination were 'not a serious problem $(63.9\%)$,' 'having no time $(22.2\%)$,' Students' recognition of the importance of health examination should be raised to increase their participation rate. When abnormal findings were detected. parents need to be informed for achieving adequate follow-up. All the students with abnormal findings need to be consulted by university health personnel to facilitate proper actions.
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