• Asian-Australasian Journal of Animal Sciences
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• 제18권10호
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• pp.1445-1450
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• 2005

This experiment was conducted to evaluate the effect of feed withdrawal (F) and heat acclimatization (A) on malebroiler and -layer chickens responses to acute heat stress (AHS) at four weeks of age. Totals of ninety male chicks of broiler or layer type were randomly allocated into 30 pens of grower batteries with raised wire floors. Chicks were subjected to F and A three times a week through the first three weeks of age. At each time, feed withdrawal and heat acclimatization (T = $35^{\circ}C$) lasted for six and four hours, respectively. Feed consumption (FC), body weight (BW), and feed conversion ratio (FCR) were recorded weekly for broiler type chickens only. At four weeks of age, all groups of chickens were exposed to AHS (T = $39{\pm}1^{\circ}C$) for three hours. Before and after AHS challenge, body temperature (Tb), heterophil (H), and lymphocyte (L) counts were recorded, and H/L ratio was calculated. Antibody (Ab) response to sheep red blood cells (SRBC) was assessed from all treatments without being exposed to AHS. Group F of broiler-type chickens weighed less (p<0.05) compared to control group. Also, both A and F groups of broiler-type chickens consumed less (p<0.05) feed when compared to control group. Acute heat stress elevated Tb of all treatment groups, however the increase was more profound (p<0.001) in broiler chicks. Broiler chicks of both A and F groups showed a tendency to have higher (p = 0.08) Tb when compared to control group. Acute heat stress elevated (p<0.001) H/L ratio in both types of chickens. Broiler chicks maintained higher (p<0.001) H/L ratio. Both F and A groups reduced (p<0.01) the level of elevation in H/L ratio compared to control groups of both types of chickens. Neither A nor F group affected the Ab production in response to SRBC. However, there was a tendency towards higher Ab responses in F group when compared to other groups in both types of chickens. Results of the present study demonstrate that previous history of feed withdrawal or episodes of heat exposures improved chicks'physiological withstanding of AHS and a tendency to improved humoral immune response.

• Journal of the Korean Wood Science and Technology
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• 제7권1호
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• pp.8-11
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• 1979

못의 보지력(保持力)인 정적인발저항(靜的引拔抵抗)에 관(關)하여 Pinus Koraiensis Sieb. et. Zucc. 재(材)와 Larix leptolepis Gord.재(材)의 두 수종(樹種)에 대하여 못 박은 후(後) 시간별(時間別) 차이(差異), 재(材)의 함수율별(含水率別) 및 Radial, Tangential, Longitudinal, 등(等)의 재(材)의 방향별(方向別)에 대해 실험(實驗)한 결과(結果)를 요약(要約)하면 다음과 같다. 1) 못을 박은 후(后) 인발저항(引拔抵抗)은 Larix leptolepis Gord. 재(材)에서는 Tangential이 최대(最大)였다.(Fig 3.) Pinus koraiensis Sieb. et. Zucc. 재(材)는 Tangential이나 Radial의 인발저항(引拔抵抗)은 차이(差異)가 없다.(Fig 2) 2) Longitudinal의 인발저항(引拔抵抗)은 두 수종(樹種) 모두 최소(最小)이다. (Fig 2, 3.) 3) 일정(一定)한 시간후(時間后)에는 Radial 및 Tangential는 두 수종(樹種)이 모두 감소(減少)한다. 4) 재(材)의 함수율(含水率)이 증가함에 따라 두 수종(樹種)이 인발저항(引拔抵抗)은 직선적(直線的)으로 감소(減少)한다. (Fig 4, 5) 5. Larix leptoleis Gord. 재(材)의 인발저항(引拔抵抗)의 감소상태(減少狀態)은 섬유포화점(纖維飽和点) 부근(附近)에서 변곡점으로 나타났다. (Fig 5)

• Asian-Australasian Journal of Animal Sciences
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• 제12권4호
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• pp.515-519
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• 1999

With the purpose of determining the influence of sexual partners on the oestrous behaviour and to evaluate the accuracy of predicting the time from implant withdrawal to sexual receptivity following a treatment with Synchromate B (SMB), 15 adult Brahman cows were used in each of three phases. During phase I and n, random pairs of animals were induced to display oestrus one pair after the other at daily intervals, while in phase III, cows were induced alternately, every other day, one cow on the 1st day, two on the 3rd, one on the 5th, two on the 7th until all cows were treated. Sixty six percent of the cows in phases I and II, and 80% in phase III came into oestrous after treatment. The interval between implant withdrawal and, expected and observed oestrous was statistically different in all phases. Clustering of oestrous was evident. Cows displayed sexual receptivity within a. range of -24 to +96; -24 to +72 and -216 to +192 hours after implant withdrawal for the three phases, respectively, with a tendency for cows treated first (within treatments), to delay their oestrus signs and vice versa. In phase III, four cows showed oestrous behaviour with the implant in place. These in spite of not observing pre-ovulatory follicles. Correlation values of 0.99, 0.93 and 0.90 (P<0.05) were found respectively among treatments, between the number of cows coming into oestrus and the number of mounts observed. These findings suggest that there are social and behavioural factors in a herd that may override exogenous synchronisation treatments.

• 대한한의학회지
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• 제28권3호통권71호
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• pp.261-272
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• 2007

Objectives : This study was conducted to determine the analgesic effect of Acanthopanax sessiliflorus using the model of neuropathic pain and formalin-induced pain. Methods : A model of neuropathic pain was made by injuring the tibial nerve and sural nerve while the common peroneal nerve was maintained. After 2 weeks, the Acanthopanax sessiliflorus was orally administered to rats. The author performed behavioral teststo try out mechanical allodynia using von frey filament and cold allodynia using acetone, which are calculated by counting withdrawal response on foot. Thirty minutes after the Acanthopanax sessiliflorus injection in the abdominal cavity, the formalin test was performed. 2% formalin in a volume of $20{\mu}l$was injected subcutaneously into the plantar surface of the hindpaw with 26-G needle. To access formalin-induced pain behavior, paw licking time was measured every 5 min. Results : The Acanthopanax sessiliflorus 400mg/10ml/kg group showed significant decrease the withdrawal response of mechanical allodynia using von frey filament in the 10min, 30min, 60min and 120min increments compared with the control group. There were no significant differences in each group in the withdrawal response of cold allodynia using acetone. The Acanthopanax sessiliflorus group showed significant decrease in the formalin-induced pain behavior in the 15min, 20min and 25min increments compared with the control group. Conclusions : The Acanthopanax sessiliflorus may have a significant analgesic effect on the general pain as well as nerve injury pain.

• The Korean Journal of Pain
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• 제23권3호
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• pp.179-185
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• 2010

Background: Vincristine-induced peripheral neuropathy is a major dose limiting side effect and thus effective therapeutic strategy is required. In this study, we investigated the antinociceptive effect of memantine and morphine on a vincristine-induced peripheral neuropathy model in rats. Methods: Male Sprague-Dawley rats weighing 220-240 g were used in all experiments. Rats subsequently received daily intraperitoneal injections of either vincristine sulfate (0.1 ml/kg/day) or saline (0.1 ml/kg/day) over 12 days, immediately following behavioral testing. For assessment of mechanical allodynia, mechanical stimuli using von Frey filament was applied to the paw to measure withdrawal threshold. The effects of N-methyl-D-aspartate receptors antagonist (memantine; 2.5, 5, 10 mg/kg intraperitoneal), opioid agonist (morphine; 2.5, 5, 10 mg/kg intraperitoneal) and vehicle (saline) on vicristine-induced neuropathy were evaluated. Results: Mechanical allodynia developed over the course of ten daily injections of vincristine relative to groups receiving saline at the same time. Morphine abolished the reduction in paw withdrawal threshold compared to vehicle and produced dose-responsiveness. Only the highest dose of memantine (10 mg/kg) was able to increase paw withdrawal threshold compared to vehicle. Conclusions: Systemic morphine and memantine have an antinociceptive effect on the vincristine-induced peripheral neuropathy model in rats. These results suggest morphine and memantine may be an alternative approach for the treatment of vincristine-induced peripheral neuropathic pain.

• The Korean Journal of Physiology and Pharmacology
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• 제20권1호
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• pp.129-136
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• 2016

This study was performed to investigate whether an intra-articular injection of transient receptor potential vanilloid 1 (TRPV1) receptor agonist, resiniferatoxin (RTX) would alleviate behavioral signs of arthritic pain in a rat model of osteoarthritis (OA). We also sought to determine the effect of RTX treatment on calcitonin gene-related peptide (CGRP) expression in the spinal cord. Knee joint inflammation was induced by intra-articular injection of monosodium iodoacetate (MIA, $8mg/50{\mu}l$) and weight bearing percentage on right and left hindpaws during walking, paw withdrawal threshold to mechanical stimulation, and paw withdrawal latency to heat were measured to evaluate pain behavior. Intra-articular administration of RTX (0.03, 0.003 and 0.0003%) at 2 weeks after the induction of knee joint inflammation significantly improved reduction of weight bearing on the ipsilateral hindlimb and increased paw withdrawal sensitivity to mechanical and heat stimuli. The reduction of pain behavior persisted for 3~10 days according to each behavioral test. The MIA-induced increase in CGRP immunoreactivity in the spinal cord was decreased by RTX treatment in a dose-dependent manner. The present study demonstrated that a single intra-articular administration of RTX reduced pain behaviors for a relatively long time in an experimental model of OA and could normalize OA-associated changes in peptide expression in the spinal cord.

• 대기
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• 제21권1호
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• pp.109-121
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• 2011

This study revisits the definition of Changma, which is the major rainy season in Korea and corresponds to a regional component of the East Asian summer monsoon system. In spite of several decades of researches on Changma, questions still remain on many aspects of Changma that include its proper definition, determination of its onset and retreat, and relevant large-scale dynamical and thermodynamical features. Therefore, this study clarifies the definition of Changma (which is a starting point for the study of interannual and interdecadal variability) using a basic concept of air mass and front by calculating equivalent potential temperature (${\theta}_e$) that considers air temperature and humidity simultaneously. A negative peak in the meridional gradient of this quantity signifies the approximate location of Changma front. This front has previously been recognized as the boundary between the tropical North Pacific air mass and cold Okhotsk sea air mass. However, this study identifies three more important air masses affecting Changma: the tropical monsoon air mass related to the intertropical convergence zone over Southeast Asia and South China Sea, the tropical continental air mass over North China, and intermittently polar continental air mass. The variations of these five air masses lead to complicated evolution of Changma and modulate intensity, onset and withdrawal dates, and duration of Changma on the interannual time scale. Importantly, use of ${\theta}_e$, 500-hPa geopotential height and 200 hPa zonal wind fields for determining Changma onset and withdrawal dates results in a significant increase (up to~57%) in the hindcast skill compared to a previous study.

• Korean Journal of Anesthesiology
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• 제71권6호
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• pp.453-458
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• 2018

Background: Pain on injection is a limitation with propofol use. The effect of the Valsalva maneuver on pain during propofol injection has not been studied. This maneuver reduces pain through the sinoaortic baroreceptor reflex arc and by distraction. We aimed to assess the efficacy of the Valsalva maneuver in reducing pain during propofol injection. Methods: Eighty American Society of Anesthesiologists class I adult patients undergoing general anesthesia were enrolled and divided into two groups of 40 each. Group I (Valsalva) patients blew into a sphygmomanometer tube raising the mercury column up to 30 mmHg for 20 seconds, while Group II (Control) patients did not. Anesthesia was induced with 1% propofol immediately afterwards. Pain was assessed on a 10-point visual analog scale (VAS), where 0 represented no pain, and 10, the worst imaginable pain, and a 4-point withdrawal response score, where 0 represented no pain, and 3, the worst imaginable pain. Scores were presented as median (interquartile range). Results: We analyzed the data of 70 patients. The incidence of pain was significantly lower in the Valsalva than in the control group (53% vs. 78%, P = 0.029). The withdrawal response score was significantly lower in the Valsalva group (1.00 [0.00-1.00] vs. 2.00 [2.00-3.00], P < 0.001). The VAS score was significantly lower in the Valsalva group (1.00 [0.00-4.00] vs. 7.00 [6.25-8.00], P < 0.001). Conclusions: A prior Valsalva maneuver is effective in attenuating injection pain due to propofol; it is advantageous in being a non-pharmacological, safe, easy, and time-effective technique.

• 한국컴퓨터정보학회논문지
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• 제15권6호
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• pp.129-138
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• 2010

본 연구는 운동중독이 신체적, 정서적 삶의 질적 가치에 영향을 줄 수 있다는 전제하에 운동참여자의 사회인구학적특성에 따른 운동중독과 정서의 성향을 분석하고 운동중독과 정서는 어떠한 관련성이 있는지를 규명하여 운동참여자의 운동중독을 예방함과 동시에 합리적인 대처방안을 제시하고자 고찰하였다. 그 결과, 운동 참여자들은 테니스를 통하여 본인의 건강 유지 증진에 대한 심리적, 정서적 안녕감이 크게 작용하고 신체적인 기술성취의 중요성으로 인하여 운동중독현상과 더불어 긍정적, 부정적인 정서에도 유의한 영향을 미친다는 결과가 나타났다. 이러한 사실을 상기하여 각 개인에게 긍정적 참여행동을 주지시키는 것은 물론 지도자들은 테니스 운동 참여자들이 보다 긍정적인 운동수행이 되도록 운동 참여행동을 제시하고 이러한 행동을 지속적으로 수행해 나갈 수 있도록 하는 것이 건강을 위한 여가의 한 형태로서 테니스 운동참여가 이루어질 수 있는 올바른 방향이라 사료된다.

• 디지털산업정보학회논문지
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• 제13권4호
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• pp.231-245
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• 2017

The purpose of this study is to analyze the trend line through scatter diagram analysis on correlation between SNS addiction tendencies and learning attitudes, figure out the knee point influencing learning attitudes negatively in detail, and examine influence among subareas. To address the goal, study questions are formulated as follows. First, this author did screening on the data of variables measured and analyzed descriptive statistics. Second, this researcher produced the trend line by drawing a scatter diagram in order to analyze correlation between SNS addiction tendencies, withdrawal symptoms, excessive communication, and excessive time wasting, and learning attitudes exploratorily. Third, to explore correlation between self-evaluation, learning participation, and developmental attitudes, the subfactors of learning attitudes related to SNS addiction tendencies, this author drew a scatter diagram and analyzed the threshold of positive and negative correlation. To verify the study questions, the SNS addiction tendency scale and learning attitude scale were applied to 301 university students in Chungcheong area. According to the study results, first, their learning attitudes are influenced by SNS addiction tendencies, excessive communication and excessive time wasting, and they are not influenced by withdrawal symptoms that much. Second, excessive communication, a factor of SNS addiction tendencies, and self-evaluation and developmental attitudes, factors of learning attitudes, show positive correlation to some extent and indicate negative correlation after the threshold. However, excessive communication and learning participation are found to show no correlation. Third, according to the results of examining correlation with learning attitudes by dividing them into excessive communication and excessive time wasting groups with the knee point of 1.40, as the symptom of excessive communication is found more, it influences self-evaluation, learning participation, developmental attitudes, and learning attitudes more negatively in general. The result of this study is expected to provide foundational material necessary to develop educational programs to prevent undergraduates' excessive SNS use and SNS addiction which can be used in the scenes of counseling or education.