• Asian Pacific Journal of Cancer Prevention
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• 제15권5호
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• pp.2159-2163
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• 2014

Background: Prostate cancer is the most frequently occurring cancer among males in economically developed countries. Among the several risk factors that have been suggested, only age, ethnicity, diabetes, and family history of prostate cancer are well-established and primary prevention of this disease is limited. Prior studies had shown that dietary intake could be modified to reduce cancer risk. We conducted a hospital-based, casecontrol study to examine the association between dietary patterns and prostate cancer risk in Iran. Materials and Methods: A total of fifty patients with prostate cancer and a hundred controls underwent face-to-face interviews. Factor analysis was used to determine the dietary patterns. Multivariate logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs). Results: We defined two major dietary patterns in this population: 'western diet'(high in sweets and desserts, organ meat, snacks, tea and coffee, French fries, salt, carbonated drinks, red or processed meat) and 'healthy diet' (high in legumes, fish, dairy products, fruits and fruit juice, vegetables, boiled potatoes, whole cereal and egg). Both Healthy and western pattern scores were divided into two categories (based on medians). Higher scores on Healthy pattern was marginally significantly related to decreased risk of prostate cancer (above median vs below median, OR =0.4, 95%CI=0.2-1.0). An increased risk of prostate cancer was observed with the higher scores on the Western pattern (above median vs below median, OR=4.0, 95%CI=1.5-11.0). Conclusions: The results of this study suggested that diet might be associated with prostate cancer among Iranian males.

• 대기
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• 제33권1호
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• pp.49-59
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• 2023

Blocking refers to a class of weather phenomena appearing in the mid and high latitudes, whose characteristics are blocked airflow of persistence. Frequently found over the Pacific and Atlantic regions of the Northern Hemisphere, blocking affects severe weather in the surrounding areas with different mechanisms depending on the type of blocking patterns. Along with lots of studies about persistent weather extremes focusing on the specific types of blocking, a new categorization using Rossby wave breaking has emerged. This study aims to apply this concept to the classification of blockings over the Pacific and examine how different wave breakings specify the associated cold weather in the Korean peninsula. At the same time, we investigate a strongly developing ridge around the Pacific by designing a new detection algorithm, where a reversal method is modified to distinguish ridge-type blocking patterns. As result, Kamchatka blocking (KB) and strong ridge over the Central Pacific are observed the most frequently during 20 years (2001~2020) of the studied period, and anomalous low pressures with cold air over the Korean Peninsula are accompanied by blocking events. When it considers the Rossby wave breaking, cyclonic wave-breaking is dominant in KB, which generates low-pressure anomalies over the Korean Peninsula. However, KB with anticyclone wave breaking appears with the high-pressure anomalies over the Korean Peninsula and it generates the warm temperature anomaly. Lastly, the low-pressure anomalies are also generated by the strong ridge over the Central Pacific, which persists for approximately three days and give a significant impact on cold surge on the Korean Peninsula.

• 한국발생생물학회지:발생과생식
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• 제25권1호
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• pp.67-72
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• 2021

This study investigated the IGF-1 signal in specific tissues using Pacific oysters artificially matured via water temperature elevation. Pacific oysters were subjected to water temperature elevation from March to June, and 20 were randomly sampled each month. The condition index (CI) and tissue weight rate (TWR) were examined by measuring shell length, shell height, shell width, and soft tissue weight. The IGF-1 signal in tissues (adductor muscle, digestive glands, gills, labial palps, mantle edges, and gonads) was analyzed by sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and Western blotting. From April to June, the TWR of females and males increased from 19.1±2.9 to 21.0±3.6 and 18.2±2.0 to 19.2±2.5, respectively, while the CI remained the same. The IGF-1 signal in each tissue differed. IGF-1 was expressed in the adductor muscle, while tyrosine was expressed in all tissues. The phosphor (p)-ERK and p-AKT activities were high in the adductor muscle, mantle edge, and gonads. IGF-1 signaling affected the growth and maturity of the Pacific oysters examined.

• 대기
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• 제31권1호
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• pp.61-71
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• 2021

The relationship between the Arctic Oscillation (AO) and surface air temperature (SAT) over Korea is re-examined using the long-term observation and reanalysis datasets for the period of December 1958 to February 2020. Over the entire period, Korean SAT is positively correlated with the AO index with a statistically significant correlation coefficient, greater than 0.4, only in the boreal winter. It is found that this correlation is not static but changes on the decadal time scale. While the 15-year moving correlations are as high as 0.6 in 1980s and 1990s, they are smaller than 0.3 in the other decades. It is revealed that this decadal variation is partly due to the AO structure change over the North Pacific. In the period of 1980s-1990s, the AO-related sea level pressure fluctuation is strong and well defined over the western North Pacific and the related temperature advection effectively changes the winter SAT over Korea. In the other periods, the AO-related circulation anomaly is either weak or mostly confined within the central North Pacific. This result suggests that Korean SAT-AO index relationship, which becomes insignificant in recent decades is highly dependent on mean flow change in the North Pacific.

• Ocean and Polar Research
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• 제40권3호
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• pp.127-143
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• 2018

This study analyzed the influence of climate change on the spawning ground area of the common squid, Todarodes pacificus. To estimate long term changes in the area of the spawning ground of the common squid, water temperature at 50 m deep that can be inferred from sea surface temperature (SST) based on both NOAA/AVHRR (1981.07-2002.12) and MODIS/AQUA (2003.01-2009.12) ocean color data was analyzed. In addition, five climate indices, Arctic Oscillation Index (AO), Siberian High Index (SH), Aleutian Low Pressure Index (ALP), East Asia Winter Monsoon Index (EAWM) and Pacific Decadal Oscillation (PDO) which are the main indicators of climate changes in the northwestern Pacific were used to study the relationship between the magnitude of the estimated spawning ground and climate indices. The area of the estimated spawning ground was highly correlated with the total catch of common squid throughout four decades. The area of the estimated spawning ground was negatively correlated with SH and EAWM. Especially, PDO was negatively correlated with the area of the spawning ground in the northwestern Pacific (r = -0.39) and in the southern part of the East Sea (r = -0.38). There was a positive relationship between the AO and the area of the spawning ground in the northwestern Pacific (r = 0.46) as well as in the southern part of the East Sea (r = 0.32). Temporally, the area of the winter spawning ground in the southern part of the East Sea in the 1980s was smaller than those areas in the 1990s and 2000s, because the area was disconnected with the western coastal spawning ground of Japan in the 1980s, while the area had been made wider and more continuous from the Korea strait to the western coastal water of Honshu in the 1990s and 2000s.

• Asian Pacific Journal of Cancer Prevention
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• 제14권1호
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• pp.507-510
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• 2013

Background: More and more research indicate that the immediately early response gene 3 (IER3) is involved inmany biological provesses, such as apoptosis and immunoreaction, as well as viral infection, tumorigenesis and tumour progression. Methods: Here we describe the construction of an eukaryotic expression vector containing IER3 gene and its expression in A549 cells as assessed through fluorescence microscopyand Western-blotting. Results: Fluorescence detection displayed that GFP in cytoplasm was high during 48 and 72 hours post-transfection. In addition, Western blotting showed significant increase in IER3 gene expression in the transfected cells compared with controls. Conclusion: The recombinate plasmid expression vector was constructed successfully, which may provide a basis for further exploration of function of IER3 in lung cancer.

• 수산해양기술연구
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• 제52권2호
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• pp.149-161
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• 2016

Fishing characteristics of Korean tuna purse seine fishery in the Pacific Ocean were investigated using logbook data compiled from captain onboard and the statistical data from 1980 to 2014. Changes in fishing ground and correlation between marine environmental factors and fishing patterns were investigated using Oceanographic index. The proportion of unassociated set was higher than that of associated set. The catch proportion of yellowfin was higher in the unassociated set, while that of skipjack and bigeye was higher in the associated set. Due to vessels, fishing gears and Korean captains' high-level of skills in fishing technology optimized for the unassociated set and preference of large fishes, especially large yellowfin tuna, it showed unique fishing characteristics focusing on the unassociated set. As for fishing distributions of Korean tuna purse seine fishery and impacts of oceanographic conditions on the fishery, the main fishing ground was concentrated on the area of $5^{\circ}N{\sim}10^{\circ}S$, $140^{\circ}E{\sim}180^{\circ}$ through the decades. When stronger El-nino occurred, the range of fishing ground tended to expand and main fishing ground moved to the eastern part of western and central Pacific Ocean. During this season, yellowfin tuna had high CPUE and catch proportion of yellowfin tuna in the eastern part also increased. As for the proportion of fishing effort by set type, proportion of log associated set was high during El-nino season while that of FAD associated set was high during La-nina season.

• Asian Pacific Journal of Cancer Prevention
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• 제14권11호
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• pp.6315-6319
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• 2013

To study the differentiated expression of the proto-oncogene Pokemon in nasopharyngeal carcinoma (NPC) cell lines and tissues, mRNA and protein expression levels of CNE1, CNE2, CNE3 and C666-1 were detected separately by reverse transcription polymerase chain reaction (RT-PCR), real-time PCR and Western-blotting. The immortalized nasopharyngeal epithelial cell line NP69 was used as a control. The Pokemon protein expression level in biopsy specimens from chronic rhinitis patients and undifferentiated non keratinizing NPC patients was determined by Western-blotting and arranged from high to low: C666-1>CNE1>CNE2> CNE3>NP69. The Pokemon mRNA expression level was also arranged from high to low: CNE1>CNE2>NP69>C666-1>CNE3. Pokemon expression of NP69 and C666-1 obviously varied from mRNA to protein. The Pokemon protein level of NPC biopsy specimens was obviously higher than in chronic rhinitis. The data suggest that high Pokemon protein expression is closely associated with undifferentiated non-keratinizing NPC and may provide useful information for NPC molecular target therapy.

• 수산해양기술연구
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• 제52권3호
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• pp.197-208
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• 2016

The WCPFC CMMs related to tropical tunas have been strongly restricting fishing capacity and operating activities of main fisheries, especially purse seine fishery. In terms of changes in fishing trend by implementing relevant measures of FAD set, the number of FAD set by Korean purse seine fleet showed a decreasing pattern with the lowest level of FAD set proportion among major distant water fishing nations. With regards to the FAD closure, there was no significant change in fishing effort but a drop in catch, especially bigeye tuna during the period of FAD closure. Moreover, it showed closely similar trends between the number of FAD set and bigeye tuna catch. In terms of measures related to the high sea area including a ban on fishing on the HSP and limitation of fishing days on the high sea by flag state, proportions of catch and effort on the high sea had sharply declined after implementing those measures. As relevant measures are expected to be strengthened, it should pay attention to change of coastal nations policies and focus on improving fishing efficiency of unassociated school set with multi-pronged efforts.

• 대한지리학회지
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• 제38권5호
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• pp.659-666
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• 2003

본 연구는 한국에 있어서 춘계 강수 분포의 변동성과 소우년과 다우년의 500hPa면의 대기 순환 특성을 비교 분석한 연구이다. 한국의 춘계 강수량 변동률의 분포는 월별로 상이하다. 3월은 한국의 서안 지역은 높고 남동안은 낮아서 서고 동저, 4월은 북고 남저, 5월은 동고 서저 경향을 나타낸다. 500hPa면의 고도편차 분포에서 3월의 소우년은 한반도 주변과 북태평양 서안에 음의 편차역을 형성하고 시베리아를 중심한 동아시아 내륙이 양의 편차를 나타내어 서고 동저형을 이루고 있다. 따라서 한반도와 그 주변은 대상풍의 동서성분 풍속은 양의 편차역에 속하여 동서류가 강할 때 소우현상이 나타난다. 다우년은 소우년과는 대조적으로 한반도는 알류샨열도 주변 및 북태평양 서안에 중심을 둔 양의 편차역에 속하고, 티베트고원 및 시베리아를 중심한 동아시아 내륙지역은 음의 편차역에 속하여 동고 서저형을 나타내며, 이 때 동서류는 약하다. 4ㆍ5월의 소우년은 북태평양의 중앙부에서 동아시아 동안에 연결된 대상의 음의 편차역에 속하며 양의 편차역은 알류샨열도에서 티베트고원에 이르는 동아시아 중부에 분포하여 북고 남저 유형을 나타내고 다우년은 소우년과 반대로 남고북저 유형을 나타내고 있다. 한반도에서의 춘계 소우년과 다우년의 출현시 대기 순환이 대조적일 뿐만 아니라 조춘과 만춘의 대기순환이 상이함을 확인하였다.