• Tuberculosis and Respiratory Diseases
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• 제46권3호
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• pp.350-362
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• 1999

연구배경: 침습적 기계 호흡 이탈에 성공하여 기관내 관을 제거하였으나 48시간 이내에 급성 호흡 부전이 경우 또는 환자 스스로 기관내 관을 제거한 후 발생된 급성 호흡 부전은 이탈 실패의 중요한 원인이며, 발생시 기관내 관의 재삽관을 통한 호흡 보조가 표준적 치료이다. 비침습적 양압 환기법(noninvasive positive pressure ventilation이하 NIPPV)은 비 혹은 안면마스크를 통해 양압 환기를 시행하므로 기관내 삽관을 회피할 수 있다. 본 연구는 기계 호흡 이탈 후 기관내 관을 제거한 환자들에게 발생된 급성 호흡 부전 시 NIPPV 적용이 기관내 삽관을 통한 양압 환기 치료를 대체할 수 있는지를 알아보고자 하였다. 방 법: 대상은 아산 재단 서울 중앙병원 내과계 중환자실에 입원하여 기계적 환기 치료를 받고 이탈 과정에서 기관내 관 제거 후 48시간 이내에 급성 호흡 부전이 발생한 환자 21명 및 스스로 기관내 관을 제거한 후 급성 호흡 부전이 발생한 환자 7명과 기관내 관이 기도내 분비물로 막혀 기관내 관을 제거한 환자 2명등 총 31명에게 NIPPV를 적용하였다. NIPPV는 환자 상태에 따라 기계 환기 양식, 압력 보조 수준 및 흡입 산소의 양이 조절 되어졌으며, 압력 보조 8cm $H_2O$미만에서 임상적으로 안정된 상태를 유지하는 경우 완전히 NIPPV에서 이탈하였다. 성공군은 NIPPV 이탈후 48 시간 이상 자발 호흡을 유지한 경우로 정의하였고, 실패군은 NIPPV 시행 후 호흡 부전 소견이나 동맥혈 가스검사의 호전이 없어 다시 기관내 삽관을 시행하여 기계호흡을 시행한 환자로 정의하였다. 각 군에서 NIPPV적용 직전, 적용 후 30분, 6시간, 24시간, NIPPV 이탈 작전 또는 실패하여 기관내 재삽관으로 전환 직전의 심박동수, 분당 호흡수, 동맥혈 가스검사, 압력 보조 수준 및 호기말 양압등을 비교하였다. 결 과: 총 31명에서 NIPPV를 적용하였고, 이 중 성공군은 14명(45%)이었다. 성공군과 실패군을 비교 시 나이, 중환자실 입원 당시의 APACHE III 점수, 기관 내 삽관 기간, 기관내 관 제거 후 NIPPV적용시까지의 시간 및 NIPPV 시행 직전의 분당 호흡수, 심박동수, 동맥혈 가스검사, $PaO_2/FiO_2$ 등은 양군간에 유의한 차이가 없었다. 모든 환자에서 NIPPV적용 30분후부터 분당 호흡수 및 심박동수는 감소하였고 동맥혈 산소 포화도는 증가하였다.(p<0.05) 그러나, 실패군에서는 NIPPV 시행중에 상태가 악화되어 기관내 재삽관을 시행하였고, 재삽관 작전의 분당 호흡수 및 심박동수는 다시 증가하였으며 동맥혈 산소포화도는 감소하였다(p<0.05). 기저 질환이 COPD 이면서 기관내 관 제거 후 급성 호흡부전이 발생한 환자 8명에게 NIPPV 적용 시 COPD가 아닌 다른 환자들에 비해 NIPPV의 성공률이 의미 있게 높았다(62% 대 39%)(p=0.007). NIPPV를 이용한 이탈 시 실패의 원인으로는 기저 질환의 악화 없이 동맥혈 가스 소견이 악화되었던 예가 9예, 그 외 기저 질환 악화 5예, 마스크 부적응이 2예, 기도내 분비물 축적이 1예였다. 결 론: NIPPV는 침습적 기계 호흡이탈과정에서 특히 기저질환이 COPD인 환자들의 경우 기관내 관 제거 후 발생한 급성 호흡 부전 시 기관내 관의 재삽관을 피할 수 있는 유용한 치료적인 방법으로 사료된다.

• 한국임상수의학회지
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• 제25권2호
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• pp.67-72
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• 2008

The aim of this study was to investigate the efficacy of Lactobacillus spp. W44 and J124 strain isolated from Kimchi on the growth rate, average daily gain (ADG), feed conversion and change of intestine microflora in the weaning piglets. In the experiment 1, growth rate was significantly increased to $28.5\;{\pm}\;4.3\;kg$ and $27.6\;{\pm}\;3.3\;kg$ after oral administration of W44 and J124 strain as feed additives, respectively (p<0.05). ADG and feed conversion were also significantly improved after administration during 44 experiment days (p<0.05). In the analysis of intestinal microflora, the number of Lactobacillus spp. in the experiment groups was significantly increased 100 to 1,000 times compared to those of control group. In the experiment 2, the efficacy of W44 and J124 strains on the growth rate, ADG, feed conversion and change of intestine microflora were reconfirmed significantly (p<0.05). However, there were no significant differences on feed conversion in the W44 bead and J124 bead groups. In summary, our results suggest that W-44 and J-124 stains from Kimchi have a significant effect on the weight gain and feed conversion, and it may be useful probiotic strains for the weaning piglets as feed additives.

• Journal of Animal Science and Technology
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• 제47권2호
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• pp.293-304
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• 2005

This experiment was carried out to investigate effects of honeybee venom treatment on the body weight gain, feed conversion and growth rate' in pigs. One hundred twenty nine piglets(LY) from 12 sows were allocated into two groups; honeybee venom-treated group (66 piglets from 6 sows) and non-treated control group (63 piglets from 6 sows). Natural honeybee venom was administrated at 0, 3, 14, 30, and 74 days after birth. The acupoints were Hai-men(ST-25), Du-kou(CV-8) and liao-chao(GV-I) points at 0 day, the regions of castration and tail ampution at 3 days, liao-chao(GV-1) and Bai-hui(GV-20) points at 14(weaning), 30(move into piglet stall) and 74(move into grower stall) days after birth. Control group was injected 1 ml of saline to the same site. Average body weight at 150 days after birth was 98.44 kg in bee venom treated group and 86.24 kg in control group, respectively. Average body weight of treated group was significantly increased by 14.15%(P < 0.0001). Average daily gain of bee venom treated group and control group were 649 g and 569 g, respectively, increased by 14.06%(P< 0.0001). Feed conversion of the treated group was 2.21 and control group was 2.49, increased by 11.25% in control group(P < 0.001). Survival rate at weaning was 95.5 % in treated group and 92.0% in control group, at growing(74 days after birth) was 92.4% in treated group and 85.7% in control group and survival rate at finishing(l50 days after birth) was 89.5 % and 79.4 %, respectively. Collecting together, the results in this study showed that growth performance and feed conversion were increased by treatment of natural honeybee venom to pigs. These results suggested that the treatment of bee venom could be used effectively for the increase productivity of livestock industry.

• Journal of Chest Surgery
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• 제57권3호
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• pp.272-280
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• 2024

Background: The phenomenon known as the "weekend effect" impacts various medical disciplines. We compared outcomes between regular hours and off hours to investigate the presence of the weekend effect in extracorporeal cardiopulmonary resuscitation (ECPR). Methods: Between January 2018 and December 2020, 159 patients at our center were treated with veno-arterial extracorporeal membrane oxygenation (ECMO) for cardiac arrest. We assessed the time required for ECMO preparation, the rate of successful weaning, and the rate of in-hospital mortality. These factors were compared among regular hours ("daytime": weekdays from 7:00 AM-7:00 PM), off hours on weekdays ("nighttime": weekdays from 7:00 PM-7:00 AM), and off hours on weekends and holidays ("weekend": Fridays at 7:00 PM to Mondays at 7:00 AM). Results: The time from the recognition of cardiac arrest to the arrival of the ECMO team was shortest for the daytime group and longest for those treated over the weekend (daytime, 10.0 minutes; nighttime, 12.5 minutes; weekend, 15.0 minutes; p=0.064). The time from the ECMO team's arrival to ECMO initiation was shortest for the daytime and longest for the nighttime group (daytime, 13.0 minutes; nighttime, 18.5 minutes; weekend, 14.0 minutes; p=0.028). No significant difference was observed in the rate of successful ECMO weaning (daytime, 48.3%; nighttime, 39.5%; weekend, 36.1%; p=0.375). Conclusion: In situations involving CPR, the time to arrival of the ECMO team was longer during off hours. Furthermore, ECMO insertion required more time at night than during the other periods. These findings warrant specific training in decision-making and emergent ECMO insertion.

• Journal of Animal Science and Technology
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• 제59권12호
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• pp.25.1-25.7
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• 2017

Background: Rabbit breeding with high performance imported ones would be of benefit for genetic diversity and improvement of performance in domestic rabbit breeds. The rearing of more productive rabbit breeds could be pathway to improve the productivity and reduce the production cost. Maternal nutritional status exert a great influence on reproductive functions of does, which may expand from conception, through gestation and parturition and development of kits to puberty. Methods: Four breeds of rabbit were evaluated for their parturition, weaning and pubertal differences among the rabbit population in Ibadan, Nigeria. The breed consist of Fauve De Bourgogne (FDB), Chinchilla (CHA), British Spot (BS) and New Zealand White (NZW) rabbits. A total of 60 bucks and 360 does consisting of 15 bucks and 90 does per breed were mated in 6 mating cycles, three each of natural mating and artificial insemination. All does were synchronized for estrus with 20 IU pregnant mare serum gonadotropin 48 h prior to mating. The does after parturition were assessed for milk yield (g) and kit survival rate (%) till weaning, weight changes of kits from birth to puberty. At puberty, the pubertal age (days) and weight (g) of the offspring were assessed. Result: Results obtained reveals that British Spot doe had highest milk yield among the breeds which significantly increased growth of kit and weight at weaning in British Spot rabbits. Survival rates of Chinchilla kits were significantly (p < 0.05) higher than Fauve de Bourgogne, British Spot and New Zealand White kits. Puberty attainment of the rabbits indicates that British spot does and Fauve de Bourgogne bucks are early maturing. Conclusion: Chinchilla shows high kit survivability and British spot has highest milk yield among the four breeds of rabbit.

• Asian-Australasian Journal of Animal Sciences
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• 제4권2호
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• pp.143-150
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• 1991

The data on reproductive performance of 1065 purebred Landrace, 1254 purebred Yorkshire. 553 purebred Duroc and 327 purebred Pietrain sows bred to farrow purebred litters and data from 3413 Landrace $\times$ Yorkshire, 487 Duroc $\times$ Pietrain and 3191 commericial litters were udsed in this study. The data were collected form litters farrowed form January 1986 to December 1988 in Holiday Hills Stock and Breeding Farms, San Prero, Laguna. The crossbred sows and litters were better in most traits associated with sow productivity than their contemporary purebred sows and litters. The Duroc $\times$ Pietrain crossbred litters showed 16.67% improvement in litter size at weaning, 10.11% improvement in survival rate form birth to weaning and 16.21% more pigs per sow pre year than the averages of their parental breeds. The litters from the Landrace $\times$ Yorkshire crossbred sows sired by either Duroc or Duroc $\times$ Pietrain boars had 11.01% bigger litter size at birth, 20.74% increase in litter size at weaning and 22.86% more pigs weaned per sow per year than the averages of the four parental breeds. Very little improvement in most traits evaluated were observed form the Landrace $\times$ Yorkshire crossbred litters compared with their parental breeds. Year of birth of litter had litter influence on sow productivity. However, the reproductivity performance declined when sows farrowed in June up to September. The best Months of farrowing were found to be from January to April. The breed $\times$ year, breed $\times$ month and year $\times$ month had no significant effects on all traits evaluated.

• Asian-Australasian Journal of Animal Sciences
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• 제15권8호
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• pp.1110-1114
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• 2002

The animal production sector in Jordan is characterized by shortages of locally produced feedstuffs derived from rangeland, forage plants or from human food crops as by products. This is exacerbated by insufficient rainfall, overgrazing, early grazing and high stocking rate. Thus, subject to these constraints, other technological improvements are highly desirable to meet the needs of crop growth and animal production. Alternative adapted technologies are also desirable in order to meet the increased demand for red meat in relation to population growth along with the changes in the price subsidy for feedstuff. The technologies are those, which have been introduced to the animal production sector, obtained in agricultural research stations besides on-farm demonstrations. They include technologies suited for increasing birth and twining rates, synchronizing the mating period, introducing the early weaning method, and animal feed and sheep production. Economic assessments conducted in this study demonstrate promising results of hormonal and nutritional practices in improving production efficiency of Awassi sheep in Jordan. Jordanian published data between 1991 and 1998 were used. The examined practices were: 1) use of PMSG in estrus synchronization in ewes, 2) introduction of early lamb weaning program, 3) supplementation with $AD_3E$ for ewes and 4) the use of agro-industrial feed block as a feed supplement for grazing lambs. Production data were then subjected to partial budgeting for economical evaluation. The use of PMSG outperformed the control groups in fertility and net returns per ewe by US$ 8.36/ewe. The early weaning of lambs increased the net returns by US$ 3.90/lamb. The injection with vitamin $AD_3E$ showed an average additional net return of US$ 5.66/ewe. Feeding agriculture by-product blocks improved weight gain in the feed block groups and resulted in additional net returns of US$ 3.5/lamb. The economic viability and reproductive performance indicators demonstrate that efforts should be undertaken to disseminate these new practices in the development program.

• Asian-Australasian Journal of Animal Sciences
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• 제13권9호
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• pp.1239-1244
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• 2000

In order to investigate the effect of incorporation of thermally processed cereal (maize) grain and differently degradable protein sources in the calf starter, twenty four newly born crossbred $(Bos\;taurus{\times}Bos\;indicus)$ calves were assigned at random to six diets in a $3{\times}2$ factorial design involving three protein sources viz. groundnut meal (GN), cottonseed meal (CS) and meat and bone meal (MB), each along with two differently processed grain, namely ground raw (R) and pressure cooked (P) maize. The corresponding calf starters with green oats (Avena sativa) were given free-choice from 14 d onwards till the end of the 90 d experimental feeding. A restricted milk diet was fed till the age of weaning at 60 d. Total DM intake was not affected by cereal or protein sources. However, daily intake of DM (59.23 vs 66.45 g) and CP (12.38 vs 14.10 g) per kg $W^{0.75}$ was reduced (p<0.05) due to cereal processing. Better (p<0.05) feed and protein efficiencies after weaning and during entire period in calves fed processed maize resulted in a trend of higher $(p{\leq}092)$ growth rate especially when GN was the source of protein. In comparison among protein sources, calves fed MB diets tended to grow faster $(p{\leq}098)$ concurrent with a higher CP intake before weaning. It is thus evident that thermal processing of maize in the calf starter seems to improve calf performance. Moreover, results indicated that feeding of protein and starch sources of matching ruminal degradability may prove beneficial for early growth of crossbred calves.

• Asian-Australasian Journal of Animal Sciences
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• 제19권8호
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• pp.1111-1119
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• 2006

The aim of this study was to analyze post-weaning reproductive performance of Large White sows in relation to season, parity and their lactation performance under tropical conditions in Guadeloupe (French West Indies, $16^{\circ}$ Lat. N, $61^{\circ}$ Long. W.). This work was based on data recorded in the experimental unit of INRA from January 1993 to December 2003. Two seasons were determined a posteriori from climatic parameters recorded continuously in a station close to the experimental unit. Mean ambient temperature was higher during the hot season than the warm season ($26^{\circ}C$ vs. $24^{\circ}C$) but relative humidity was comparable for both seasons (i.e. 87% on average). Season had a significant effect on all reproductive parameters analyzed. Primiparous sows weaned in the hot season had a higher probability of a prolonged weaning to estrus interval, WEI (odds ratio was 4.1; p<0.01) but multiparous sows were not affected. A higher probability of a prolonged weaning to conception interval, WCI (odds ratio >2.5, p<0.01) and a lower subsequent farrowing rate (-10%, p<0.01) were found for sows weaned in the hot season. A higher daily feed intake during lactation reduced the probability of a prolonged WEI (p<0.05). Body weight and average back-fat thickness at farrowing affected WEI and WCI (p<0.05), whereas body weight and average backfat thickness change in lactation did not. This study confirms the negative effects of the hot season on primiparous reproductive performance. It also indicates that lactation performance influences sow non-productive period.

• Journal of Chest Surgery
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• 제30권1호
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• pp.34-39
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• 1997

1994년 5월부터 1995년 12월까지 성인에서 심장수술을 시행한 122례중 18례(14.8%)에서 IABP를 순환보조장치로 사용하였다. 그중 술전에 IABP(intra-aortic balloon pump)를 시행한 경우는 9례이고, 술 중에는 7례, 그리고 술후에는 2례에서 시행하였다. 그 이유는 술전에는 저심박출, PTCA(percutaneous transluminal coronary angioplasty)의 실패였고, 술중에는 체외순환기 이탈을 위해서이며, 술후에는 술후 발생한 부정 맥 때문이었다. 환자들의 평균 나이는 61.8$\pm$6.9세(39세에서 75세)였다. 술전 및 술중에 IABP를 시행한 환자의 수술사망율은 각각 33.3, 42.9%였으며 술후 IABP를 시행한 환자는 모두 생존하였다. IABP이탈율은 술전의 경우 66.77%. 술중의 경우 85.7%였으며 술후에 시행한 IABP는 모두 이탈 가능하였다. 결론적으로 IABP는 심근 손상이 가역적인 시기에 적용할 경우, 수술전후 어느시기에나 안전하게 사용가능하며 수술전후의 혈류역학적 불안정, 체외순환기 이탈 및 저심박출증의 치료에 도움을 줄 수 있다고 판단된다.