• 제목/요약/키워드: weakly large

검색결과 102건 처리시간 0.03초

랫드 척수신경절내 zinc의 분포양상: Zinc Selenium Autometallography (Histochemically-reactive Zinc in the Rat Dorsal Root Ganglion (DRG) Neurons: Zinc Selenium Autometallography)

  • 김이석;조승묵
    • Applied Microscopy
    • /
    • 제40권1호
    • /
    • pp.15-19
    • /
    • 2010
  • 이번 연구에서는 성체 랫드(Sprague-Dawley)의 척수신경절내 분포하는 zinc의 분포 관찰하기 위하여 zinc selenium autometallograpy(AMG)로 염색하였다. H-E염색표본에서 척수신경절 속에는 신경절세포들이 무리지어 분포하고 있었고, 세포체는 둥글거나 타원형이었으며, 작은 신경절세포, 큰 신경절세포로 대별되었다. 모든 신경절세포의 세포체는 한 층의 납작한 위성세포(satellite cell)에 의하여 둘러싸여 있었다. AMG 염색표본에서는 작은 신경절세포의 경우 강한 양성반응이 핵 주변부에서 관찰되었으나, 큰 신경절세포의 경우 전반적으로 미약한 AMG 양성반응을 보였고, 염색양상도 서로 달랐다. 그러나 큰 신경절세포를 둘러싸는 위성세포에서는 뚜렷한 AMG 양성반응이 관찰되었다. 이러한 조직화학적 본 연구의 결과는 zinc가 감각신경절인 랫드 척수신경절에서 통증을 포함한 감각의 전달과정에 의미있는 기능을 영위할 수 있음을 시사한다.

Rhizoctonia균의 배양특성 및 잔디에 대한 병원성과 살균제의 효과 (Studies on Cultural Characteristics and Pathogenicity of Rhizoctonia spp. and Effect of Fungicides)

  • 이두형;유왕근;한경숙
    • 아시안잔디학회지
    • /
    • 제6권2호
    • /
    • pp.89-98
    • /
    • 1992
  • Rhizoctonia oryzae, R. oryzae-sativae 및 R. solani의 균사융합군의 각 균주에 대한 배양특성과 creeping bentgrass 및 들잔디에 대한 병원성과 살균제의 효과에 대하여 조사하였던 바 다음과 같다. 1. 균사생육에 미치는 온도의 영향을 보면 네가지 형으로 나눌 수 있는데, R. oryzae와 R. oryzae-sativae는 생육적온이 $30~35^{\circ}C$인 호고온형이었고, R. solani의 균사융합군의 각 균주도 세가지 형으로 나뉘었는데, 즉 생육적온이 $25~30^{\circ}C$인 고온형, 20~25$^{\circ}C$인 중간형 및 $20^{\circ}C$인 저온형이었다. 2. 접종실험에서 creeping bentgrass에 대해서는 R. oryzae와 R. solani의 AG-1( I A), AG-1( I B), bentgrass분리균 및 벼 분리균이 강한 병원성을 나타냈고, 그 다음으로 AG-2-1, AG-4, AG-5 및 AG-2-2가 중 또는 약한 병원성을 나타냈다. 들잔디에 대해서는 R. oryzae와 R. solani의 들잔디 분리균이 강한 병원성을 나타냈고 AG-1( I B)와 AG-5가 중정도의 병원성을 나타냈다. 3. 살균제의 효과는 creeping bentgrass의 brown patch병과 들잔디의 large patch병에 대해서 capro와 mytan등이 가장 좋았고 brown patch병에 대해서는 thiopan과 pencycuron이, large patch병에 대해서는 tolos와 thiopan이 각각 그 다음으로 좋았다.

  • PDF

간척지대에 매설된 대구경 금속관의 외면 부식손상 평가 (Assessment of external corrosion deterioration of large diameter metallic water pipes buried in reclaimed land)

  • 이호민;최태호;김정현;배철호
    • 상하수도학회지
    • /
    • 제34권5호
    • /
    • pp.373-383
    • /
    • 2020
  • The purpose of this study was to evaluate the corrosion damage of large diameter metallic pipes buried in reclaimed land due to the corrosion effect by soil, and to propose a method of installing metal pipes in the reclaimed land. The results are as follow. First, the soil of the reclaimed land was gray clay, the soil specific resistance indicating soil corrosiveness was at least 120 Ω-cm, the pH was weakly acidic(5.04 to 5.60), the redox potential was at least 62 mV, the moisture content was at most 48.8%, and chlorine ions and sulfate ions were up to 4,706.1 mg/kg and 420 mg/kg. Therefore, the overall soil corrosivity score was up to 19, and the external corrosion effect seems to be very large. Second, the condition of straight part of pipes was in good condition, but most of KP joints were affected by corrosion at a severe level. The reason for this seems to be that KP joints accelerated corrosion due to stress and crevice corrosion in addition to galvanic corrosion in the same environment. Third, as a result of evaluating correlations of each item that affects the corrosion on the external part, the lower the soil resistivity and redox potential, the greater the effect on the KP joints corrosion, and the moisture content, chloride ion, and sulfate ion, the higher the value, the greater the effect on the corrosion of KP joints. In addition, among soil corrosion items, the coefficient of determination of soil resistivity with corrosion of KP joints was the highest with 0.6439~0.7672. Fourth, when installing metal pipes or other accessories because the soil of the reclaimed land is highly corrosive, it is necessary to apply a corrosion preventive method to extend the life of pipes and prevent leakage accidents caused by corrosion damage to the joint.

개의 구토물에서 분리한 오디흑연가시(철선충)의 전자현미경을 이용한 해부학적 소견 (Anatomical Study of Chordodes koreensis in the Parasitic Phase Using Electron Microscopy)

  • 손화영;채준석;김남수;김현철;조정곤;박배근
    • 한국임상수의학회지
    • /
    • 제26권6호
    • /
    • pp.586-590
    • /
    • 2009
  • 철선충은 주로 사마귀와 같은 곤충에 기생하는 선충류로 사람이나 동물은 우연히 감염될 수 있는 것으로 알려져 왔다. 철선충의 생활사는 크게 곤충에 기생하는 기생생활기, 그리고 발육이 완료된 후에 숙주를 죽이고 외계로 나와 자유생활을 하는 자유생활기로 구분할 수 있다. 본 연구는 개의 구토물에서 오디흑연가시 수컷을 발견하여 이의 횡단면을 주사 및 투과 전자현미경으로 관찰한 것이다. 전자현미경하에서 표피는 4층(epicuticle, cuticle, epidermis, muscle)으로 이루어졌고, 내강에는 장, 배신경절이 발견되었다. 그러나 고환은 발견되지 않았다. 표피의 최상층에서 여러 형태의 areoles이 관찰되었으며, cuticle은 17열의 섬유로 이루어져 있었다. Epidermis는 1열로 구성되어 있었으며, muscle층은 여러 개의 근세포가 종으로 일정하게 배열되어 있었다. 그리고 내강에 배신경절이 충체의 정중앙 배측에서만 존재하는 것으로 확인되었다. 이러한 결과로 본 철선충은 기생생활기를 끝내지 못한 미성숙충으로 판단된다.

Properties of Single $K^{+}$ Channels of Skeletal Muscle Incorporated into Planar Lipid Bilayer

  • Park, Jin-Bong;Kim, Hee-Jeong;Cho, Myung-Haing;Lee, Hang;Park, Hong-Ki;Lee, Mun-Han;Ryu, Pan-Dong
    • The Korean Journal of Physiology
    • /
    • 제29권1호
    • /
    • pp.13-27
    • /
    • 1995
  • single $K^{+}$ channels of skeletal muscle from the rat and frog were into planar lipid bilayers and their properties were studied. Fusion was induced by an osmotic gradient. Of the four types of $K^{+}$ channels recorded, the two most frequently observed were a voltage and $Ca^{2+}-activated$ $K^{+}$ channel and a $K^{+}$ channel with a prominent conductance substate. The first $K^{+}$ channel was identified as the large $Ca^{2+}-activated$ $K^{+}$ (BK) channel because the open-state probability was increased with depolarization (e-fold change per $10.6{\pm}3.5$ mV, n=8) and internal $Ca^{2+}$ (half-activation at $16.7{\pm}3.8$ mV, n=8, pCa 4) and its conductance was large ($247{\pm}4.9$ pS, n=24 in 0.1 M KCI). Lifetime distributions of open- and closed-states could be fitted with single exponentials of several milliseconds. The mean open- and closed-lifetimes were linearly dependent on the intracellular $[Ca^{2+}]$ and $1/[Ca^{2+}]$, respectively. The second $K^{+}$ channel showed a conductance substate at $30{\sim}60%$ of the open state. Its current-voltage relation was linear in the range of $-80\;{\sim}\;+80\;mV$. The slope conductance of the substate and open-state were 40 and 144 pS in 0.2 M KCl, respectively. The channel was highly selective for $K^{+}$ over Cl. The open-state probability was weakly voltage-dependent (e-fold change per 35 mV. The lifetime distributions of open- and closed-states were fitted with two exponentials and the major gating occurred slowly at several hundred milliseconds. Based on the above results, we think the second type of $K^{+}$ channel is the sarcoplasmic reticulum $K^{+}$ (SRK) channel. In addition, both types of channel were also incorporated into the lipids extracted from the skeletal muscle. The channel properties recorded in the bilayers termed from synthetic and extracted lipids were qualitatively similar. Our data indicate that BK and SRK channels are rich in the skeletal muscle and their properties and regulation could be effectively studied in planar lipid bilayer.

  • PDF

ACCELERATION OF COSMIC RAYS AT COSMIC SHOCKS

  • KANG HYESUNG
    • 천문학회지
    • /
    • 제36권1호
    • /
    • pp.1-12
    • /
    • 2003
  • Nonthermal particles can be produced due to incomplete thermalization at collisionless shocks and further accelerated to very high energies via diffusive shock acceleration. In a previous study we explored the cosmic ray (CR) acceleration at cosmic shocks through numerical simulations of CR modified, quasi-parallel shocks in 1D plane-parallel geometry with the physical parameters relevant for the shocks emerging in the large scale structure formation of the universe (Kang & Jones 2002). Specifically we considered pancake shocks driven by accretion flows with $U_o = 1500 km\;s^{-l}$ and the preshock gas temperature of $T_o = 10^4 - 10^8K$. In order to consider the CR acceleration at shocks with a broader range of physical properties, in this contribution we present additional simulations with accretion flows with $U_o = 75 - 1500 km\;s^{-l}$ and $T_o = 10^4K$. We also compare the new simulation results with those reported in the previous study. For a given Mach number, shocks with higher speeds accelerate CRs faster with a greater number of particles, since the acceleration time scale is $t_{acc}\;{\propto}\;U_o^{-2}$. However, two shocks with a same Mach number but with different shock speeds evolve qualitatively similarly when the results are presented in terms of diffusion length and time scales. Therefore, the time asymptotic value for the fraction of shock kinetic energy transferred to CRs is mainly controlled by shock Mach number rather than shock speed. Although the CR acceleration efficiency depends weakly on a well-constrained injection parameter, $\epsilon$, and on shock speed for low shock Mach numbers, the dependence disappears for high shock Mach numbers. We present the 'CR energy ratio', ${\phi}(M_s)$, for a wide range of shock parameters and for $\epsilon$ = 0.2 - 0.3 at terminal time of our simulations. We suggest that these values can be considered as time-asymptotic values for the CR acceleration efficiency, since the time-dependent evolution of CR modified shocks has become approximately self-similar before the terminal time.

Simulated Optimum Substrate Thicknesses for the BC-BJ Si and GaAs Solar Cells

  • Choe, Kwang-Su
    • 한국재료학회지
    • /
    • 제22권9호
    • /
    • pp.450-453
    • /
    • 2012
  • In crystalline solar cells, the substrate itself constitutes a large portion of the fabrication cost as it is derived from semiconductor ingots grown in costly high temperature processes. Thinner wafer substrates allow some cost saving as more wafers can be sliced from a given ingot, although technological limitations in slicing or sawing of wafers off an ingot, as well as the physical strength of the sliced wafers, put a lower limit on the substrate thickness. Complementary to these economical and techno-physical points of view, a device operation point of view of the substrate thickness would be useful. With this in mind, BC-BJ Si and GaAs solar cells are compared one to one by means of the Medici device simulation, with a particular emphasis on the substrate thickness. Under ideal conditions of 0.6 ${\mu}m$ photons entering the 10 ${\mu}m$-wide BC-BJ solar cells at the normal incident angle (${\theta}=90^{\circ}$), GaAs is about 2.3 times more efficient than Si in terms of peak cell power output: 42.3 $mW{\cdot}cm^{-2}$ vs. 18.2 $mW{\cdot}cm^{-2}$. This strong performance of GaAs, though only under ideal conditions, gives a strong indication that this material could stand competitively against Si, despite its known high material and process costs. Within the limitation of the minority carrier recombination lifetime value of $5{\times}10^{-5}$ sec used in the device simulation, the solar cell power is known to be only weakly dependent on the substrate thickness, particularly under about 100 ${\mu}m$, for both Si and GaAs. Though the optimum substrate thickness is about 100 ${\mu}m$ or less, the reduction in the power output is less than 10% from the peak values even when the substrate thickness is increased to 190 ${\mu}m$. Thus, for crystalline Si and GaAs with a relatively long recombination lifetime, extra efforts to be spent on thinning the substrate should be weighed against the expected actual gain in the solar cell output power.

CMIP5 기후 모형에서 나타나는 북서태평양 아열대 고기압의 변동성 (Variability of the Western North Pacific Subtropical High in the CMIP5 Coupled Climate Models)

  • 김은진;권민호;이강진
    • 대기
    • /
    • 제26권4호
    • /
    • pp.687-696
    • /
    • 2016
  • The western North Pacific subtropical high (WNPSH) in boreal summer has interannual and interdecadal variability, which affects East Asian summer monsoon variability. In particular, it is well known that the intensity of WNPSH is reversely related to that of summer monsoon in North East Asia in association with Pacific Japan (PJ)-like pattern. Many coupled climate models weakly simulate this large-scale teleconnection pattern and also exhibit the diverse variability of WNPSH. This study discusses the inter-model differences of WNPSH simulated by different climate models, which participate in the Coupled Model Intercomparison Project phase 5 (CMIP5). In comparing with reanalysis observation, the 29 CMIP5 models could be assorted into two difference groups in terms of interannual variability of WNPSH. This study also discusses the dynamical or thermodynamics factors for the differences of two groups of the CMIP5 climate models. As results, the regressed precipitation in well-simulating group onto the Nino3.4 index ($5^{\circ}N-5^{\circ}S$, $170^{\circ}W-120^{\circ}W$) is stronger than that in poorly-simulating group. We suggest that this difference of two groups of the CMIP5 climate models would have an effect on simulating the interannual variability of WNPSH.

Mutagenicity and Antimutagenicity of Hydrophilic and Lipophilic Extracts of Thai Northern Purple Rice

  • Punvittayagul, Charatda;Sringarm, Korawan;Chaiyasut, Chaiyawat;Wongpoomchai, Rawiwan
    • Asian Pacific Journal of Cancer Prevention
    • /
    • 제15권21호
    • /
    • pp.9517-9522
    • /
    • 2014
  • Purple rice (Oryza sativa L. var. indica) cv. Kum Doisaket is cultivated in northern Thailand. This study evaluated the mutagenic and antimutagenic properties of hydrophilic and lipophilic components of purple rice using the Ames test. The seed and hull of purple rice were extracted with hexane, methanol, ethanol, and water. The methanol extracts had the highest amounts of phenolic acids and flavonoids, while the hexane extracts contained large amount of tocols and ${\gamma}$-oryzanol. None of the extracts were mutagenic in Salmonella typhimurium strains TA98 and TA100. The hexane extract of rice hull and the methanol extract of rice seed were strongly effective against aflatoxin B1- and 2-amino-3, 4 dimethylimidazo (4, 5-f) quinoline-induced mutagenesis, while aqueous extracts showed weakly antimutagenic properties. All extracts with the exception of aqueous extracts enhanced the number of revertant colonies from benzo (a) pyrene induced-mutagenesis. None of the extracts inhibited mutagenesis induced by the direct mutagens 2-(2-furyl)-3-(5-nitro-2-furyl)-acrylamide and sodium azide. The hull extracts showed more potent antimutagenicity than the seed extracts. Based on a chemical analysis, ${\gamma}$-oryzanol and ${\gamma}$-tocotrienol in the hull and cyanidin-3-glucoside and peonidin-3-glucoside in the seed are candidate antimutagens in purple rice. The antimutagenic mechanisms of purple rice might be related to either modulation of mutagen metabolizing enzymes or direct attack on electrophiles. These findings supported the use of Thai purple rice as a cancer chemopreventive agent.

POLARIZATION OF LYMAN α EMERGENT FROM A THICK SLAB OF NEUTRAL HYDROGEN

  • AHN, SANG-HTEON;LEE, HEE-WON
    • 천문학회지
    • /
    • 제48권3호
    • /
    • pp.195-202
    • /
    • 2015
  • Star forming galaxies found in the early universe exhibit asymmetric Lyα emission line that results from multiple scattering in a neutral thick medium surrounding the Lyα emission source. It is expected that emergent Lyα will be significantly polarized through a large number of resonance scattering events followed by a number of successive wing scatterings. In this study we adopt a Monte Carlo method to calculate the polarization of Lyα transferred in a very thick static slab of HI. Resonantly scattered radiation associated with transitions between is only weakly polarized and therefore linear polarization of the emergent Lyα is mainly dependent on the number of off-resonant wing scattering events. The number of wing scattering events just before escape from the slab is determined by the product of the Doppler parameter a and the line center optical depth τ0, which, in turn, determines the behavior of the linear polarization of Lyα. This result is analogous to the study of polarized radiative transfer of Thomson scattered photons in an electron slab, where the emergent photons are polarized in the direction perpendicular to the slab when the scattering optical depth is small and polarized in the parallel direction when the slab is optically thick. Our simulated spectropolarimetry of Lyα shows that the line center is negligibly polarized, the near wing parts polarized in the direction parallel to the slab and the far wing parts are polarized in the direction perpendicular to the slab. We emphasize that the flip of polarization direction in the wing parts of Lyα naturally reflects the diffusive nature of the Lyα transfer process in thick neutral media.