• Title/Summary/Keyword: water-soluble polymer

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Modification of Nonwoven Poly(vinyl alcohol) Fabrics (I) - Reaction of Water Soluble Poly(vinyl alcohol) Nonwoven Fabrics with Phosphoryl Chloride - (폴리비닐알콜 부직포의 개질에 관한 연구 (I) - 수용성 폴리비닐알콜 부직포와 POCl3의 반응 특성 -)

  • Lee, Won-Chul;Kim, Chang-Sup;Jang, Sang-Hee;Song, Du-Hyun;Lyoo, Won-Seok;Gal, Yeong-Soon
    • Textile Coloration and Finishing
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    • v.20 no.6
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    • pp.75-81
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    • 2008
  • This paper dealt with the synthesis and characterization of the polymeric product by the reaction of the water-soluble poly(vinyl alcohol)[PVA] nonwoven fabrics and the phosphoryl chloride ($POCl_3$), which has been applied to prepare water-proofing materials or intermediates for increasing water-proofing or fire-proofing ability of commercially available water-soluble PVA support layer. $POCl_3$ was reacted with PVA nonwoven fabrics under non-aqueous condition, and their reactivity, and chemical structure were checked and discussed. PVA was reacted with $POCl_3$ under the reaction condition of 1:1, or 1:2 mole ratios at 70, 80 and $90^{\circ}C$, and the reaction products were further hydrolyzed. The structure of the resulting products from water soluble PVA nonwoven fabrics reacted with $POCl_3$ were identified by FT-IR or X-ray fluorescence spectrophotometer, and they indicated the PVA polymer chains to have phosphorous and chlorine moieties.

Change of Physical/Mechanical Property of Human Hair by Treatment using Water Soluble Chitosan (수용성 키토산 처리에 의한 모발의 물리적/역학적 특성 변화)

  • Kim, Kyung-Sun;Jeon, Dong-Won;Kim, Jong-Jun
    • Journal of the Korean Society of Clothing and Textiles
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    • v.33 no.10
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    • pp.1655-1664
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    • 2009
  • Chitosan is an environment-friendly and natural cationic polymer that can be used as a hair cosmetic additive. Healthy hair and damaged hair samples were experimented on according to treatment conditions using a water-soluble chitosan. Chitosan treated hair samples were studied on the physical and mechanical property changes. It is most effective when the water-soluble chitosan treatment was adjusted to the Neutral (pH6.8) or Acid (pH4.5). When the water soluble chitosan was treated at pH4.5, the tensile strength, tensile elongation, and elasticity of decolorized hair all increased. The virgin and damaged hair both changed into elastic and soft hair. The effect of chitosan treatment is more noticeable in the healthy hair than in the damaged hair.

Studies on Dosage Form Design of Anticancer Drug: Release of 5-Fluorouracil from Silicone Devices Containing Water Soluble Additives (항암제(然癌劑) 제형(劑形) 개발(開發)에 관(關)한 연구(硏究) : Silicone Rubber-수용성(水溶性) 첨가제(添加劑)의 Device에서 5-Fluorouracil의 용출(溶出))

  • Kim, Sung-Ho;Choi, Jun-Shik;Back, Chae-Sun;Yu, Young-Jong;Lee, Chi-Young
    • Journal of Pharmaceutical Investigation
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    • v.16 no.1
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    • pp.1-7
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    • 1986
  • The influences of sodium chloride, polyethylene glycol 4000 and 20000 on 5-fluorouracil release from disk type silicone polymer devices were examined in isotonic phosphate buffer. These water soluble cosolvent and sodium chloride caused devices to swell in aqueous media. Sodium chloride exerted the greatest influence on drug release. The addition of water soluble cosolvent or sodium chloride to silicone polymeric devices permitted controlled release of 5-fluorouracil, presumably due to the change of the physical microstructure of silicone network, and the solubility and diffusivity of 5-fluorouracil. It seemed that the water soluble drug was released through the hydrophilic pores or pathways formed in the device by the incorporation of a water soluble cosolvent or sodium chloride.

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A Fundamental study of Fine Dust Reduction of Dust Inhibitor using Water Soluble Polymer (수용성 폴리머를 사용한 비산먼지 방지제의 미세먼지 저감에 관한 기초적 연구)

  • Lim, Sung-Gyu;Cho, In-Seong;Lee, Han-Seung
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2020.11a
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    • pp.38-39
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    • 2020
  • Since a lot of fugitive dust is generated at construction and civil engineering construction sites in Korea, the fine dust regulation at construction sites has been strengthened in accordance with the implementation of the Special Act on Fine Dust Reduction. In a construction site, water is generally sprayed to temporarily reduce the generation rate of scattered dust, but there is a problem that when water evaporates, it scatters again. In this study, the performance of a scattering dust inhibitor incorporating a polymer that stabilizes the ground and reduces the rate of scattering dust by forming a polymer film even when water evaporates using a polymer and a surfactant was evaluated.

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Solubilization of poorly water-soluble drugs using solid dispersions

  • Kim, Tae-Wan;Choi, Choon-Young;Cao, Qing-Ri;Lee, Beom-Jin
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.412.2-413
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    • 2002
  • Purpose. To prepare polymer based physical mixtures or solid dispersions containing solubilizing compositions using a spray-dryer. Methods. Lovastatin.simvastatin.aceclofenac and cisapride were selected as poorly water-soluble drugs. Dextrin. poly(vinylalcohol). poly(vinylpyrrolidone)and polyethylene glycol were chosen as solubilizing carriers for solid dispersions. The solid dispersions containing solubilizing compositions without drug were prepared without using organic solvents or tedious changes of formulation compositions. (omitted)

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Effect of Polyethylene Glycol on Release of Heparin from Silicone Segment Devices (실리콘 segment device로부터의 헤파린 방출에 미치는 폴리에틸렌글리콜의 영향)

  • 김성호
    • YAKHAK HOEJI
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    • v.29 no.2
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    • pp.70-75
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    • 1985
  • The influence of polyethylene glycol derivatives on heparin release from cylindrical monolithic type silicone segment devices was examined in physical saline solution. This water-soluble carrier caused the devices to absorb the water in aqueous media. The release rate of heparin from the devices was increased as molecular weight of polyethylene glycol was increased. Water soluble carrier incorporated into silitone segment devices permits controlled release of heparin that otherwise would be released extremly slowly from the polymer. Heparin released from the silicone segment containing polyethylene glycol showed the first-order kinetics. Without changing the release-pattern, the release rate of heparin could be controlled by varing molecular weight of polyethylene glycol, the water-soluble carrier and depleting polyethylene glycol on the outlayer of devices. The mechanism of release probably showed the creation of pore or microdomine through the devices secondary to the swelling.

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The Synthesis of Artery Wall Targeted Gene Carrier Using Low Molecular Water-Soluble Chitosan (저분자량 수용성 키토산을 이용한 동맥 벽 표적성 유전자 전달체의 합성)

  • Choi Chang-Yong;Jang Mi-Kyeong;Nah Jae-Woon
    • Polymer(Korea)
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    • v.30 no.4
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    • pp.279-285
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    • 2006
  • Non-viral gene carriers continue to attract a great deal of interest due to advantageous safety profile. Among the non-viral gene carriers, cationic liposomes or synthetic gene carriers are efficient DNA carriers in vitro. but their in vivo applications are greatly hampered because of low biocompatibility. On the other hand, chitosan, a natural cationic polysaccharide, is a candidate non-viral vector for gene delivery because of its low cytotoxicity and high positive charges. In this work, targeted gene carrier was synthesized to target artery wall cells using low molecular water-soluble chitosan (LMWSC). The molecular weight $(M_W)$ and degree of de acetylation (DDA) of LMWSC were measured by relative viscometer and Kina titration. respectively. The structure of LMWSC was analyzed by measuring FTIR, $^1H-NMR,\;and\;^{13}C-NMR$. AWBP-PEG-g-LMWSC was synthesized by conjugation of the artery wall binding peptide (AWBP), a specific targeting peptide, to the end of pegylated LMWSC as a gene carrier to target artery wall cells. The synthesized AWBP-PEG-g-LMWSC were analyzed by measuring FTIR, $^1H-NMR$, zeta -potentiometer, and atomic force microscopy (AFM).