• Biomedical Science Letters
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• v.24 no.3
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• pp.239-244
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• 2018

Recently, many researches regarding the natural products which alternate with chemical products have been done. Among them, boswellia is well known for effect on anti-oxidative effect and inflammation. The aim was the effect boswellia of formalin- induced orofacial and temporomandibular joint (TMJ) pain on experimental animals was investigated. Experiments were carried out using subcutaneous (SC) pain model and TMJ pain model that were induced by the injection of 5% formalin into the right vibrissa pad (SC, $50{\mu}L$) or TMJ ($30{\mu}L$) of rats, respectively. In both models, formalin (5%), formalin after distilled water (vehicle), formalin after boswellia extract (p.o., concentrations of 15, 30 mg/kg) (n=6). The number of scratching on the injected region was scored during the 9 successive periods of 5 min intervals following injection of formalin. Oral administration of boswellia (15, 30 mg / kg) reduced formalin-induced SC orofacial pain behavioral responses. SC orofacial pain behavioral responses was significantly reduced at 20~35 min. In the experimental group injected into temporomandibular joints, the pain response was significantly reduced by $276.2{\pm}8.20$ and $78.3{\pm}4.7$ after oral administration of boswellia (15, 30 mg / kg) at $398.3{\pm}24.8$ times. As a result of the passage of time, the oral administration of boswellia showed a significant effect of reducing the temporomandibular joint pain 30 minutes after the injection of formalin. This study confirmed that oral administration of boswellia modulated the pain behavior in both models. In conclusion, boswellia extract may be a potential therapeutic treatment for orofacial pain.

• Biomedical Science Letters
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• v.26 no.2
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• pp.93-100
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• 2020

Xerostomia is a relatively common oral disease that causes various problems such as pain, discomforted, tissue damage, and infection. When the activity of AQPs, which plays an important role in the microbial channel transmembrane activity in tissues, decreases saliva secretion and the oral cavity dryness occurs. In this study, we observed whether there was a change in tissue through the expression level of AQP-5 in the submandibular gland in the 4-DAMP-induced xerostomia model. First, in order to construct a xerostomia model, 4-DAMP (1 mg/kg) and 20% urethane (0.5 mL/kg) were administered intraperitoneal (i.p.) to experimental animals. To observe the changes in the submandibular gland was excised, H&E staining was performed and protein quantitation analysis was performed using the submandibular tissue to observe the changes in AQP5 protein expression involved in changes in saliva secretion. Also, cinnamaldehyde (5, 12.5, 25 and 50 mg/kg) dissolved in 20% DMSO, in distilled water for each concentration, and then orally administered at a dose of 1 mL for biopsy and protein quantitative analysis. As a result, it was observed that the submandibular tissue, a model of xerostomia was wider than the naïve group. And then western blot analysis, the expression level of AQP5 decreased in the 4-DAMP group compared to the naïve group, and the expression increased in the group administered orally with cinnamaldehyde. Therefore, administration of 4-DAMP resulted in histological changes for xerostomia, and cinnamaldehyde would be a material that can be developed by reducing xerostomia.

• Membrane and Water Treatment
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• v.9 no.4
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• pp.255-262
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• 2018

This study attempted to evaluate the process of self-forming dynamic membrane formation on mesh filter in membrane bioreactor with a two-stage method of batch (agitation) and continues (aeration) stage at different sludge concentrations. Four concentrations of activated sludge including $6{\pm}0.4$, $8{\pm}0.5$, $10{\pm}0.3$, $14{\pm}0.3g/L$ were used to demonstrate the optimal concentration of sludge for treating municipal wastewater and reducing fouling in dynamic membrane bioreactor. The formation time and effluent turbidity were decreased in the batch stage when increasing the activated sludge concentration. The minimum values of formation time and effluent turbidity were 14 min and 43 NTU for the optimum mixed liqueur suspended solids of $8{\pm}0.5g/L$, respectively. To improve operational condition and fouling reduction in the aeration stage, critical fluxes were measured for all concentrations by flux-step method. With increasing the sludge concentration, the relevant critical fluxes reduced. The optimum subcritical flux of $30L/m^2/h$ was applied as operating flux in the second stage. The maximum COD removal efficiency of 98% was achieved by the concentration of $8{\pm}0.5g/L$. Compressibility index of self-forming dynamic membrane and transmembrane pressure trend remained somewhat constant until the optimal concentration of $8{\pm}0.5g/L$ and thereafter they increased steeply.

• Journal of Ginseng Research
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• v.39 no.4
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• pp.331-337
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• 2015

Background: The biological actions of various ginseng extracts have been studied for treating obesity and diabetes mellitus. However, few studies have evaluated the effects of fermented Korean Red Ginseng (Panax ginseng Meyer) on metabolic syndrome. The present study evaluated the antiobesity and antidiabetic effects of fermented red ginseng (FRG) on old-aged, obese, leptin-deficient (B6.V-Lepob, "ob/ob") mice. Methods: The animals were divided into three groups and given water containing 0%, 0.5%, and 1.0% FRG for 16 wk. The effect of FRG on ob/ob mice was determined by measuring changes in body weight, levels of blood glucose, serum contents of triglycerides, total cholesterol and free fatty acids, messenger RNA (mRNA) expressions of key factors associated with insulin action, such as insulin receptor (IR), lipoprotein lipase (LPL), glucose transporter 1 and 4 (GLUT1 and GLUT4), peroxisome proliferators-activated receptor gamma ($PPAR-{\gamma}$), and phosphoenolpyruvate carboxykinase (PEPCK) in the liver and in muscle, and histology of the liver and pancreas. Results: FRG-treated mice had decreased body weight and blood glucose levels compared with control ob/ob mice. However, anti-obesity effect of FRG was not evident rather than hypoglycemic effect in old aged ob/ob mice. The hyperlipidemia in control group was attenuated in FRG-treated ob/ob mice. The mRNA expressions of IR, LPL, GLUT1, GLUT4, $PPAR-{\gamma}$, and PEPCK in the liver and in muscle were increased in the FRG-treated groups compared with the control group. Conclusion: These results suggest that FRG may play a vital role in improving insulin sensitivity relative to reducing body weight in old-aged ob/ob mice.

• Journal of the Korea Safety Management & Science
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• v.12 no.3
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• pp.121-128
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• 2010

This is to show some basic data for introducing both circulated aggregate and recycled powder producing waste concrete. Standard-mixing design for 24MPa has been basically used and added and replaced normal aggregate with recycled powder made of waste concrete. In addition, polycarboxylate high-range water reducing agent has been used because recycled powder is missing adhesive strength and it is not compare with cement's adhesive strength. Compressive strength with powder mixture of 2%, 4%, 6%, 8%, and 10% has been decreased down to 80% of normal concrete material strength without recycled powder mixture. $200^{\circ}C$, $400^{\circ}C$ and $600^{\circ}C$ heated concrete were compressively tested in order to find out concrete strength resistant to high temperature. heat capacity was also tested, based on the expectancy of its low conductivity. In addition, thermal conduction test was tested in order to find out concrete insulation. According to this test, when concrete was tested by fire resistance, it using the circulation aggregate was same resulted by concrete using the natural aggregate. also, recycle powder was not effecting insulation performance. but it is fit to standard on concrete insulation of building law.

• Elastomers and Composites
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• v.55 no.1
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• pp.26-39
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• 2020

The physical properties of silica-filled SBR compounds (WSBR) prepared using silica-SBR wet masterbatches (WMB) were systematically investigated to understand the effect of the surface treatment of silica on the reinforcement performance of SBR. Treatment of silica with bis(triethoxysilylpropyl)tetrasulfide (TESPT) in the liquid phase, followed by mixing with an SBR solution and recovery by water stripping, easily produced silica-SBR WMB. However, insufficient surface treatment in terms of the amount and stability of the incorporated TESPT led to considerable silica loss and inevitable TESPT elution. Pretreatment of silica in the gas phase with TESPT and another organic material that enabled the formation of organic networks among the silica particles on the surface provided hydrophobated silica, which could be used to produce silica-SBR WMB, in high yields of above 99%. The amount and type of organic material incorporated into silica greatly influenced the cure characteristics, processability, and tensile and dynamic properties of the WSBR compounds. The TESPT and organic material stably incorporated into silica increased their viscosity, while the organic networks dispersed on the silica surface were highly beneficial for reducing their rolling resistance. Excessive dosing of TESTP induced low viscosity and a high modulus. The presence of connection bonds formed by the reaction of glycidyloxy groups with amine groups on the silica surface resulted in physical entanglement of the rubber chains with the bonds in the WSBR compounds, leading to low rolling resistance without sacrificing the mechanical properties. Mixing of the hydrophobated silica with a rubber solution in the liquid phase improved the silica dispersion of WSBR compounds, as confirmed by their low Payne effect, and preservation of the low modulus enhanced the degree of entanglement.

• Journal of Acupuncture Research
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• v.30 no.3
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• pp.165-171
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• 2013

Objectives : The purpose of this study is to investigate the effect of acupuncture treatment on a patient suffering from CRPS Type 1. Methods : A 30-year-old female patient suffering from CRPS Type 1 with symptoms of intense burning pain, joint stiffness, restricted mobility, rapid hair and nail growth, allodynia, hyperalgesia and coldness of the right leg was treated with acupuncture on six acupuncture points on the leg from 13 July to 18 July of 2011. Improvement of the patient's symptoms was evaluated by Numerical Rating Scale(NRS), Digital Infrared Thermographic Image(DITI). Results : After 6 days of treatment, NRS score decreased significantly and the DITI results showed moderate improvement in temperature. Conclusions : The results suggest that acupuncture may be an effective in reducing the symptoms of CRPS. Further study is needed to evaluate the significancy of this report.

• Journal of the Korean Dietetic Association
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• v.24 no.1
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• pp.1-18
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• 2018

Sustainable practices of school foodservices are gaining more attentions. The study aimed to investigate dietitians' performance levels of sustainable practices in school foodservice settings in Gyeonggi Provinces. Using a survey method was used, and data were collected from 358 participants (response rate 59.7%) to be analyzed using the SPSS program. The evaluation tool for sustainable practices of school foodservices consisted of four sections and 34 criteria with 100 points. Employment status of the respondents was as follows: nutrition teachers 40.9%, dietitians (permanent) 45.1%, and temporary position dietitians 13.2%. Dietitians' performance for sustainable practices marked 65.67 points out of 100 (performance rate 66%) and were in the following order by section: sustainable foodservice management criteria (69%), support activities (69%), planning and evaluation (68%), and outcome management (52%). Regarding sub-sections, criteria that acquired higher performance rates were labelling of food origin (99%), use of seasonal vegetables and fruits (98%), food waste management by contract dealer (98%), and planning for reducing of food waste and solid waste (91%). Meanwhile, criteria that showed the lowest scores were installing water conservation devices on equipment (19%), operating food donation programs for communities (21%), use of sensor lights for electricity conservation (24%), planning for annual energy conservation (40%), and implementation of education programs for foodservice workers on sustainable activities (42%). Performance scores differed according to school levels and working experience of dietitians, indicating that dietitians at elementary school foodservices or with work experience of 15 to 20 years showed higher performance than those at high schools or with less than 5 years of work experience (P<0.001, P<0.05). Based on the results, action plans for improvement were suggested.

• Korean Journal of Soil Science and Fertilizer
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• v.46 no.3
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• pp.143-152
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• 2013

No-till farming system has been extensively studied all over the world as the effective method for maintaining the soil fertility. The general advantages of this system have been well known for reducing the labor, fuel, machinery, and irrigation cost as well as for increasing the soil quality through soil aggregation, water infiltration, microbial population and etc. Recently, it becomes more popular with the increase of interest on sustainable agriculture, especially because of its higher carbon sequestration potential compared to conventional tillage. Crop residue management should be essentially included to look forward to achieving the positive effect on reduction of greenhouse gas. Nonetheless, there are also negative opinions on effect of no-till farming system. For example, some researchers reported that soil physical properties were not improved by no-till under certain soil and climatic conditions. This means no-till farming systems were strongly affected by the soil characters and climatic conditions. Therefore, the researches to meet the specific-regional characters are greatly needed in order for no-till farming system to successfully settle in Korea. The objective of the review article is to present the future direction and perspective on no-till farming system in Korea. For this purpose, we summarized the results of domestic and foreign researches about no-till farming system until now. Specifically, the chapter on foreign research consisted of four parts: positive and negative effects, the effect in paddy soil, and latest research direction (2012-2013) of no-till farming systems. Whereas, review for domestic researches was divided into two main parts: paddy and upland soils. In the final chapter, the priorities for the optimum conservation tillage in Korea were discussed and proposed through the previous researches.

• Smart Structures and Systems
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• v.17 no.1
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• pp.149-165
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• 2016

Floods have been known to be one of the main causes of bridge collapse. Contrary to earthquakes, flood events tend to occur repeatedly and more frequently in rainfall areas; flood-induced damage and collapse account for a significant portion of disasters in many countries. Nevertheless, in contrast to extensive research on the seismic fragility analysis for civil infrastructure, relatively little attention has been devoted to the flood-related fragility. The present study proposes a novel methodology for deriving flood fragility curves for bridges. Fragility curves are generally derived by means of structural reliability analysis, and structural failure modes are defined as excessive demands of the displacement ductility of a bridge under increased water pressure resulting from debris accumulation and structural deterioration, which are known to be the primary causes of bridge failures during flood events. Since these bridge failure modes need to be analyzed through sophisticated structural analysis, flood fragility curve derivation that would require repeated finite element analyses may take a long time. To calculate the probability of flood-induced failure of bridges efficiently, in the proposed framework, the first order reliability method (FORM) is employed for reducing the required number of finite element analyses. In addition, two software packages specialized for reliability analysis and finite element analysis, FERUM (Finite Element Reliability Using MATLAB) and ABAQUS, are coupled so that they can exchange their inputs and outputs during structural reliability analysis, and a Python-based interface for FERUM and ABAQUS is newly developed to effectively coordinate the fragility analysis. The proposed framework of flood fragility analysis is applied to an actual reinforced concrete bridge in South Korea to demonstrate the detailed procedure of the approach.