• Journal of Nutrition and Health
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• v.34 no.3
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• pp.271-284
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• 2001

This study was performed to investigate the effects of dried powders and water extracts of Paecilomyces tenuipes(P. tenuipes) and Cordyceps militaris(C. militaris) on lipid metabolism, lipid peroxidation and antioxidative capacity and immune status in rats. Thirty-five male Sprague-Dawley rats weighting 195$\pm$21g were grouped into five according to body weight. Ratw were raised for four weeks with diet containing either 4%, 2%(w/w) of dried P. tenuipes powders(TP-4, TP-2) or water extracts from equal amounts of each 4% P. tenuipes and C. militaris powder(TE-4, ME-4). Food intake, weight gain of all groups were not significantly different from those of control group. Lipid metabolism in general was not significantly different among all the groups. However both dried P. tenuipes powder lowered plasma cholesterol level slightly, water extract groups showed tendency of higher plasma HDL-cholesterol and lower liver cholesterol levels than control. Plasma and liver thiobarbituric acid reactive substance(TBARS) concentrations of all the experimental groups were lower than control group. Red blood cell(RBC) and liver superoxide dismutase(SOD) activities were not generally different among all groups. Liver xanthine oxidase(XOD) activities of all groups were tended to be lower than control group. Proliferation of aplenocytes induced by mitogens, concanavalin A and lipopolysaccharide, were increased in TP-2 group. The TP-4 group showed increased CD8 T cells and MHC class II expression without changes in CD4 T cells, B cells and G/M ratio, suggesting activated cytotoxic T cell activity in vivo. Increase of G/M ratio but not of MHC class II in TP-2 group indicated the possible acute inflammatory reaction by the ingested substances in gastrointestinal tract. ME-4 group showed enhanced cellular immunity without vigorous changes of immune parameters in brief periods. In conclusion, both P. tenuipes and C. militaris stimulated antioxidant capacity and immune status in rats. Among groups, water extract of C. militaris was most effective in both capacities, though dried powder of P. tenuipes at 2% dietary level was more effective in antioxidant activity, as various results by different strains were observed.(Korean J Nutrition 34(3) : 271~284, 2001)

• Journal of Korea Water Resources Association
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• v.40 no.8
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• pp.601-615
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• 2007

A selective withdrawal method has been widely used to control the quality of water released from a stratified reservoir and to improve downstream ecosystem habitats. Recently, several existing reservoir withdrawal facilities have been modified to accommodate multi-level water intake capabilities in order to adapt the impact of long-term discharge of high turbidity flow. The purpose of this study was to assess the effect of selective withdrawal method on the control of downstream turbidity and its impact on water quality in Daecheong Reservoir. A laterally integrated two-dimensional hydrodynamic and eutrophication model, which was calibrated and validated in the previous studies, was applied to simulate the temporal variations of outflow turbidity with various hypothetical selective withdrawal scenarios. In addition, their impacts on the algal growth as well as water quality constituents were analyzed in three different spatial domains of the reservoir The results showed that the costly selective withdrawal method would provide very limited benefits for downstream turbidity control during two years of consecutive simulations for 2004-2005. In particular, an excessive withdrawal from the epilimnion zone for supplying upper layer clean water resulted in movement of turbidity plume that contained high phosphorus concentrations upward photic zone, and in turn increased algal growth in the lacustrine zone.

• Water for future
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• v.24 no.1
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• pp.119-128
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• 1991

This study was focused on establishing the concepts of the instream flow to prevent the problems for the conceptual ambiguity and the difference in the instream flow estimation methods. The average drought flow is defined as the flow required to guarantee the minimum function of the river such as prevention of drying. The environmental control flow is defined as the flow required to control optimal river environment, the flow required for navigation, prevention of sea water-intrusion, protection of river management facilities, conservation of water Quality, fishing, prevention of river mouth closure, control of groundwater level, protection of animals and plants, and landscape. The average drought flow was obtained by flow duration analysis for the natural flows in the Han River at Indo-Bridge gaging station. When considering the 9 factors related to environment conservation, the conservation of water quality was proved to be most important. The pollutants for the river flows were estimated and the water qualities were forecasted. After comparing the water qualities in the future and water quality standards, there quired optimal dilution flow was estimated. The average drought flow and environmental control flow are all non-consumptive flows. Therefore larger flow between them, i.e., Max. (average drought flow, environmental control flow) can be the instream flow. The river management flow can be added to the flows for water utilization in the downstream. The results from this study are expected to be very helpful in the systematic river management on the other main rivers in Korea.

• Journal of Korean Society on Water Environment
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• v.23 no.4
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• pp.504-511
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• 2007

Built-out issue of copper processing appearing recently in the Paldang watershed is a critical problem to deteriorate the basic framework of national water management policy as well as to be simply a copper-related problem. Up to now, Korea government has invested hard and relevant upstream areas have been victimized readily in a variety of field to comply its goal of 'Safe Water Supply'. Because of the reason, the desirable water quality level of the Paldang watershed has been maintained regardless of its dense population. Paldang drinking water management policy is based on residents' understanding which is considered as a 'social capital'. The issue raised in the aspect of water quality management policy should be reviewed on the basis of the 'social capital' concept. One regarding semiconductor industry as a potential industry to export many products in 10 years insists that the industry not be a simple private business but be a prominent part for national competitiveness. There is no doubt about this opinion. However, a nation should support environmental right-to-life of its people prior to any other tasks. In other words, it is really risky to give up people's right due to economic benefits. Therefore, it should not happen to trade 'life', the dignity of man, with national competitiveness which is likely to be preferred in these days. In addition, coherent policy not to destroy 'social capital' promoting Paldang drinking water resource management policy should be maintained.

• Journal of Institute of Control, Robotics and Systems
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• v.6 no.2
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• pp.127-137
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• 2000

This paper presents a novel neural based controller which controls the water level of the nuclear power plant steam generator. The controller consists of a model reference feedback linearization controller and a PI controller for stabilizing the feedback linearization controller. The feedback linearization controller consists of a neural network model and an inversing module which uses the neural network model for computing the control input to the steam generator. We chose Piecewise Linearly Trained Network(PLTN) and Recurrent Neural Netwrok(RNN) for an approximator of the plant and used these approximators in calculating the input from the feedback linearization controller. Combining the above two controllers gives a result of better performance than the case which uses only a PI controller Each control result of PLTN and RNN is given.

• Journal of Nutrition and Health
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• v.39 no.8
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• pp.721-727
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• 2006

This study was conducted to investigate the effects of Aralia elata, Acanthopanacis cortex and Ulmus davidiana water extracts on blood hemoglobin, $HbA_{1c}$, levels and biomarkers in the streptozotocin (STZ)-induced diabetic rats. Male Wistar rats divided into normal and diabetic groups. The diabetic groups subdivided into the control group (DM) and Araliaceae water extracts supplemented groups: Aralia elata (AE), Acanthopanacis cortex (AC) and Ulmus davidiana (UD). The extracts were supplemented in diet base on 11.42 g of raw Araliaceae/kg diet for 7 weeks. The diabetes was induced by injecting 572 (55 mg/kg B.W., i.p.) once 2 weeks before sacrifying. Relative weights of liver were significantly lowered in the DM group compared to the normal group, whereas those of kidney and heart were significantly increased in the DM group. Supplementation of the Araliaceae water extracts improved reduced liver weights in STZ-induced diabetic rats. Blood glucose level was significantly higher in the DM group than in the normal group, whereas insulin contents were significantly lowered in the DM groups. However, these parameters were normalized in the An, AC and UD supplemented groups, respectively. Blood hemoglobin and $HbA_{1c}$ levels were significantly higher in the DM group than in the normal group. When all of Araliaceae water extracts were supplemented to the diabetic rats lowered hemoglobin and $HbA_{1c}$ levels. Red blood cell, white blood cell and Lymphocyte were significantly higher in the DM group than in the normal group. The supplementation of Araliaceae family water extracts significantly lowered these parameters compared to the DM group. MCV, MCH contents were declined in the DM group, while the supplementation of Aralia elata, Acanthopanacis cortex and Ulmus davidiana water extracts elevated of these contents in STZ-induced diabetic rats. Accordingly, these results indicate that Aralia elata, Aeanthopanacis corex and Ulmus davidiana water extracts would seem to improve the blood biomarkers in STZ-induced diabetic rats.

• The Korea Journal of Herbology
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• v.37 no.4
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• pp.1-8
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• 2022

Objectives : Dioscorea batas Decaisne (DB) has been known to be good for the digestive system on Eastern Asia. However, the protective effect of DB on acute pancreatitis (AP) has not been studied. In this study, we tried to investigate the protective effect of DB water extract on caerulein-induced AP. Methods : To measure the protective effect of DB on AP, Mice were injected with cholecystokinin analogue caerulein (50 ㎍/kg) hourly for 6 times. DB water extract (200 or 400 mg/kg) or saline (control group) was administered orally 1 h before the first injection of caerulein. The mice were sacrificed at 6 h after the last injection of caerulein. The pancreas tissues and serum samples were immediately taken for further analysis. Results : Administration of DB water extract showed the inhibitory effect on the increase of pancreas weight/body weight ratio, pancreatic histological damage. And the rise of serum lipase level was significantly reduced in DB water extract treatment group during AP in mice. However administration of DB water extract did not show significant reduction in serum amylase level. Also, mRNA levels of pro-inflammatory cytokines Interleukin (IL)-6 and Tumor necrosis factor (TNF)-𝛼 but not IL-1𝛽 were inhibited by administration of DB water extract. Conclusions : Taken together, we found that administration of DB water extract ameliorates the severity of caerulein-induced AP, which suggests the potential to be an effective treatment on AP.

• The Plant Pathology Journal
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• v.22 no.3
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• pp.295-302
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• 2006

The present study addressed the efficacy of nanosized silica-silver for controlling plant pathogenic microorganisms. The nanosized silica-silver consisted of nano-silver combined with silica molecules and water soluble polymer, prepared by exposing a solution including silver salt, silicate and water soluble polymer to radioactive rays. The nanosized silica-silver showed antifungal activity against the tested phytopathogenic fungi at 3.0 ppm with varied degrees. In contrast, a number of beneficial bacteria or plant pathogenic bacteria were not significantly affected at 10 ppm level but completely inhibited by 100 ppm of nanosized silicasilver. Among the tested plant pathogenic fungi, the new product effectively controlled powdery mildews of pumpkin at 0.3 ppm in both field and greenhouse tests. The pathogens disappeared from the infected leaves 3 days after spray and the plants remained healthy thereafter. Our results suggested that the product developed in this study was effective in controlling various plant fungal diseases.

• Korean Journal of Pharmacognosy
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• v.33 no.2 s.129
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• pp.120-123
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• 2002

The possibility of Galla Rhois(GR) water extract as an antithrombotic agent was investigated. The effect of GR on platelet aggregation in human platelet-rich plasma(PRP) induced by collagen and ADP in vitro and coagulation parameters in a pathological model induced by endotoxin and hydrocortisone acetate(HA) in vivo were examined. In platelet aggregation assay, GR extract significantly inhibited platelet aggregation induced by collagen and ADP in a dose-dependent manner. GR extract significantly increased the number of platelet and shortened prothrombin time(PT) and activated thromboplastin time(APTT) as compared with the control in pathological model induced by endotoxin and HA. Also, GR extract significantly increased fibrinogen level as compared with the control in a pathological model induced HA. These results suggest that GR may be a promising antithrombotic agent.

• Computers and Concrete
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• v.12 no.1
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• pp.65-77
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• 2013

This paper examines the dynamic response of an arch dam subjected to blast loading. A damage model is developed for three dimensional analysis of arch dams. The modified Drucker-Prager criterion is adopted as the failure criteria of the damage evolution in concrete. Then, Xiluodu arch dam serves as an example to simulate the failure behaviors of structures with the proposed model. The results obtained using the proposed model can reveal the reliability degree of the safe operation level of the high arch dam system as well as the degree of potential failure, providing a reliable basis for risk assessment and risk control.