• Nuclear Engineering and Technology
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• v.52 no.2
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• pp.397-416
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• 2020

Investigations of the commercial aircraft impact effect on nuclear island infrastructures have been drawing extensive attention, and this paper aims to perform the safety assessment of Generation III nuclear power plant (NPP) buildings subjected to typical commercial aircrafts crash. At present Part II, based on the verified finite element (FE) models of aircrafts Airbus A320 and A380, as well as the NPP containment and auxiliary buildings in Part I of this paper, the whole collision process is reproduced numerically by adopting the coupled missile-target interaction approach with the finite element code LS-DYNA. The impact induced damage of NPP plant under four impact locations of containment (cylinder, air intake, conical roof and PCS water tank) and two impact locations of auxiliary buildings (exterior wall and roof of spent fuel pool room) are evaluated. Furthermore, by considering the inner structures in the containment and raft foundation of NPP, the structural vibration analyses are conducted under two impact locations (middle height of cylinder, main control room in the auxiliary buildings). It indicates that, within the discussed scenarios, NPP structures can withstand the impact of both two aircrafts, while the functionality of internal equipment on higher floors will be affected to some extent under impact induced vibrations, and A380 aircraft will cause more serious structural damage and vibrations than A320 aircraft. The present work can provide helpful references to assess the safety of the structures and inner equipment of NPP plant under commercial aircraft impact.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.40 no.4
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• pp.481-486
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• 1995

The salt stress at seedling stage of winter barley was examined in different concentrations of NaCl containing 1/2 Hoagland solution. Fresh weight of seedling at 30 days after seeding was highest at 25mM of NaCl concentration containing 1/2 Hoagland solution but if the NaCl concentration was more than 50mM it began to decrease seriously. Water content in plant was decreased according to increase of NaCl concentration in 1/2 Hoagland solution, so physiological mechanism of NaCl in barley was different from saline plant. Stoma number per cm$^2$ of first leaf was higher than that of control in case of stressed by NaCl but in that case the leaf length was decreased so the number of stoma per first leaf was slightly decreased. Chloroplast shape was not changed by 75mM of high NaCl contained 1/2 Hoagland solution but cell division at root growing point was inhibited by 75mM of NaCl. As the result of salt stress mitochondria was ruined in structure and irregular solid was found to be transfered from the cytoplasm to the cell wall in root growing point.

• Development and Reproduction
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• v.20 no.2
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• pp.81-90
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• 2016

The effect of sudden changes of water temperature (WT) on the survival rate and physiological responses of the red spotted grouper (Epinephelus akaara) were examined by manipulating WT control system for 9 days. Experimental condition was divided in two different regimes at low (from $10^{\circ}C$ to $4^{\circ}C$, decreased $1^{\circ}C/d$) and high (from $28^{\circ}C$ to $34^{\circ}C$, increased $1^{\circ}C/d$) WT. Survival rate of experimental fishes were observed, and determined the changes of hematological characteristics by analyzing plasma levels of cortisol, glucose, total protein, and electrolytes ($Na^+$, $Cl^-$, $K^+$). No mortality was observed until low WT $6^{\circ}C$ (144 h) and high WT $32^{\circ}C$ (96 h), and 100% mortality was observed at low WT $4^{\circ}C$ (216 h) and high WT $35^{\circ}C$ (171 h). Plasma levels of cortisol and glucose increased rapidly as decreasing WT, and the loss of swimming ability and respiration response was observed at low WT $7^{\circ}C$ and high WT $34^{\circ}C$ conditions.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.292-292
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• 2017

This study was conducted to evaluate the effect of anti-obesity and antioxidant enzyme activities in vitro by different solvent fractions from the roots of Codonopsis lanceolata. The cytotoxicity of different solvent fractions of C. lanceolata on 3T3-L1 preadipocytes were evaluated using the MTT assay, the rate of cell survival progressively decreased in a dose-dependent manner. Butyl alcohol fraction at $200{\mu}g/mL$ exhibited a pronounced cytotoxic effect (75.73%) on 3T3-L1 cell comparable to that of the hexane fraction (79.82%), methylene chloride fraction (84.02%), ethyl acetate fraction (87.62%) and DW fraction (86.30%) at the same concentration. The Oil Red O solution was used to determine whether different solvent fractions of C. lanceolata induce adipocyte differentiation in 3T3-L1 preadipocytes. Confluent 3T3-L1 cells were treated with $50{\mu}g/mL$ concentration of solvent fraction extracts from C. lanceolata. Inhibitory degree of lipid accumulation against solvent fraction extracts showed a significant level compared with the control. Both lipid accumulation and adipocyte differentiation showed relatively high effect on methyl chloride fraction. The root extract of C. lanceolata had the highest SOD enzyme activity of 84.5% in ethyl acetate partition layer and while water partition layer of diploid showed the lowest SOD enzyme activity of 57.9%. The activity of CAT, APX and POD showed a significantly higher activity in ethyl acetate partition layer compared with the other fraction. These results suggested that the roots of C. lanceolata may assist in the potential biological activity on anti-obesity and antioxidant capacity.

• Journal of Dairy Science and Biotechnology
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• v.35 no.2
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• pp.93-97
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• 2017

Linum usitatissimum L. (flaxseed) is emerging as an important functional food ingredient because of its rich contents, namely, ${\alpha}$-linolenic acid (ALA, omega-3 fatty acid), lignans, and fiber, which are potentially beneficial for human health. Furthermore, flax or flaxseed oil has also been incorporated as a functional food ingredient into various foods such as milk, dairy products, and meat products. Flaxseed is known to possess antimicrobial activity in vitro and in vivo, but its growth-stimulating effect on lactic acid bacteria is not clear. Hence, the objective of this study was to determine whether crude flaxseed extract stimulated the growth kefir-isolated lactic acid bacteria in vitro. The result of this study showed that Lactobacillus kefiranofaciens DN1, Lactobacillus brevis KCTC3102, Lactobacillus bulgaricus KCTC3635, and Lactobacillus plantarum KCTC3105 treated with $100{\mu}L$ of crude flaxseed extract showed significantly higher growth than the control treated with $100{\mu}L$ of water (p<0.05). Based on the results of this study, crude flaxseed extract could be used as a growth stimulator for lactic acid bacteria in various food applications, including production of milk and dairy products.

• Horticultural Science & Technology
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• v.32 no.4
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• pp.463-472
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• 2014

Ion imbalance in recycled nutrient solutions is caused by selective ion uptake of plants, which occurs at different rates in different growth stages. The objectives of this study were to investigate the ion balances in both recycled nutrient solutions and rockwool media using different renewal patterns for the nutrient solutions, and to analyze the subsequent effects on uptake of water and nutrients. Over 12 weeks of paprika cultivation, two different renewal patterns (week units) of 6-4-2 and 8-2-2 weeks were compared with a constant renewal pattern of 4-4-4 weeks (control). The nutrient solution in the reservoir tank was constantly maintained at EC $2.5dS{\cdot}m^{-1}$ and pH 5.5-6.5. The changes in the ion balance with the 4-4-4 week pattern were smaller than those with the other treatments. In the early growth stage, however, the ion balances similarly changed among all treatments. Greater changes were subsequently observed for the 6-4-2 week pattern. Although fruit yield and shoot fresh weight of paprika were the lowest with 6-4-2 renewal pattern, no significant differences were observed. Our results indicate that renewal intervals can be extended in consideration of growth stage for more efficient and practical operations in closed soilless cultures.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.4 no.1
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• pp.16-23
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• 2001

This study was conducted to analyse the relation between physical characteristics of soil surface and wild plants occurrence. Lots of natural occurrence on loamy soil and a little of natural occurrence on perlite. Those were used to observe the wild plants occurrence through the duration. Natural occurrence of wild plants were observed on uniform sand, perlite, loamy soil and 2cms loamy soil layer above the perlite. Uniform sand was compared with different height of drain ditch. The results of analysis were as followed. 1. Wild plants germinated on the uniform perlite layer, they did not grow larger. Because water in large pores of perlite surface drained rapidly and evaporated easily, therefore surface remained low moisture contents. 2. A lot of weed grew on 2cms loamy layer on perlite which stratified above the perlite layer. Because perlite had plenty of soil moisture and soil moisture moved easily from perlite to loamy soil layer. 3. Uniform loamy soil had similar occurrence on the uniform perlite. It was nearly same at surface moisture distribution but lower than layered loamy soil on perlite, and the vertical distributions at soil moisture was totally lower than 2cms loamy soil layer on perlite. 4. Wild plants were grew on uniform sand on different height of drain ditch. In this case, much more wild plants were grew on which had more higher drainage ditch. The number of wild plants occurred when it was affected by soil surface moisture, drain ditch and natural occurrence of wild plants. This could be controlled by layered soil at surface moisture. Therefore weed occurrence can control in planting ground, where soil layer would not be disturbed.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.16 no.4
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• pp.99-114
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• 2013

In this study, constructability of ecologocal stream restoration process was evaluated and improved approaches for habitat were suggested. The study site is Gucheon River in Geoje city where conducted ecologocal restoration work within maintaining its flood control function. Application of ecological design factors and constructability in the process from planning to construction was analyzed and its results are as follows: In the process of planning and designing, it was focused more on the naturality of Gucheon River rather than the human convinience and ecological design factors were applied within the ecological capacity of the site. First, the indexes for constructability evaluation is selected. It was classified into three major categories as construction quality, design quality and construction administration system. Each index has details, so there are twenty sub indexes for contractibility evaluation. Second, the evaluation results shows that the index most in need of improvement was plumbing construction, followed by Stone construction and pavement construction. design concept was evaluated as appropriate in entire categories. Finally it is suggested that it can be improved in both process of design to enhance the technology and process of construction to enhance the quality management. The constructability of ecological stream needs adaptive management and it must be discussed with its designing which is at the stage before construction. Also it needs discussion with its designer constantly and feed-back process.

• Korean Journal of Pharmacognosy
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• v.44 no.1
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• pp.60-69
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• 2013

The worldwide prevalence and severity of allergic diseases including atopic and contact dermatitis has increased dramatically over the past decade, especially in developed countries. Mast cells are important effector cells in allergic reactions. The purpose of this study was undertaken to investigate the anti-allergic and anti-pruritic effects of Diospyros lotus leaf extract (DLE). DLE was prepared by extracting with distilled water. In the present study, we investigated the effect of DLE on the production of tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$), interleukin-$1{\beta}$ (IL-$1{\alpha}$) and histamine in rat peritoneal mast cells (RPMCs), and on the skin lesion, leukocyte infiltration and scratching behavior in mice. Phorbol 12-myristate 13-acetate (PMA) plus calcium ionophore A23187 significantly increased TNF-${\alpha}$ and IL-$1{\beta}$ production compared with media control. However, TNF-${\alpha}$ and IL-6 production increased by PMA plus A23187 treatment were significantly inhibited by DLE in a dose-dependent manner. DLE also inhibited the histamine release from RPMCs stimulated by compound 48/80, which promotes histamine release. Moreover, DLE administration had an inhibitory effects on the scratching behavior induced by pruritogen (compound 48/80, histamine) in ICR mice. Furthermore, DLE inhibited the skin lesions, inflammatory and mast cells in hairless mice sensitized by 2,4-dinitrofluorobenzene (DNFB). DLE administration reduced the IL-4 and IgE production induced by DNFB sensitization in hairless mice. These results suggest that DLE has a potential use as a herb medicine for treatment against allergy and pruritus-related disease.

• Toxicological Research
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• v.23 no.4
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• pp.383-389
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• 2007

Recombinant human granulocyte-macrophage colony stimulating factor (hGM-CSF) regulates proliferation and differentiation of hematopoietic progenitor cells and modulates function of the mature hematopoietic cells. In the previous study, we reported that hGM-CSF could be produced in transgenic rice cell suspension culture, termed rhGM-CSF. In the present study we examined the single and repeated dose toxicity of rice cells-derived hGM-CSF in SD rats. During single dose toxicity study for 7 days, there were no any toxic effects at any dose of from 10 to $1000{\mu}g/kg$. The lethal dose ($LD_{50}$) was not found in this range. Moreover, repeated dose toxicity study of 14-days period and at the doses of 50 and $200{\mu}g/kg$ (i. v.) of rhGM-CSF did not show any changes in food and water intake. There were also no significant changes in both body and organ weights between the control and the test groups. The hematological and blood biochemical parameters were statistically not different in all the groups. These results suggest that rhGM-CSF has no toxicity in SD rats.