• Gut and Liver
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• v.12 no.6
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• pp.623-632
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• 2018

Intestinal Behçet's disease is a rare, immune-mediated chronic intestinal inflammatory disease; therefore, clinical trials to optimize the management and treatment of patients are scarce. Moreover, intestinal Behçet's disease is difficult to treat and often requires surgery because of the failure of conventional medical treatment. Administration of anti-tumor necrosis factor-${\alpha}$, a potential therapeutic strategy, is currently under active clinical investigation, and evidence of its effectiveness for both intestinal Behçet's disease and inflammatory bowel diseases has been accumulating. Here, we review updated data on current experiences and outcomes after the administration of anti-tumor necrosis factor-${\alpha}$ for the treatment of intestinal Behçet's disease. In addition to infliximab and adalimumab, which are the most commonly used agents, we describe agents such as golimumab, etanercept, and certolizumab pegol, which have recently been shown to be effective in refractory intestinal Behçet's disease. This review also discusses safety issues associated with anti-tumor necrosis factor-${\alpha}$, including vulnerability to infections and malignancy.

• Proceedings of the KIEE Conference
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• 2008.07a
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• pp.157-158
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• 2008

전 세계적으로 광역정전에 대한 많은 연구가 진행되고 있다. 본 논문에서는 I-PIU를 통해 동기화된 데이터를 취득 이용하여 실시간 계통 감시는 물론 광역정전 방지에 대한 방향을 마련하는데 목적을 두고 있다. 또한 민감도(Sensitivity Factor)와 취약도(Vulnerability Index)를 이용한 예측 알고리즘의 적용으로 실시간 계통의 상황감시는 물론 계통의 위험을 미리 알리는 거리계전기 모니터링 시스템을 설계하였다. 이는 운영자로 하여금 계통의 위험 요소를 적절한 조치를 취해 제거함으로써 치명적인 정전 사고 방지와 효율적 관리는 물론 앞으로의 광역정전 방지를 위한 역할을 기대할 수 있다.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2016.10a
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• pp.347-350
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• 2016

Analysis of vulnerability of the software for risk. The weakness of the software material, the importance of strengthening security in accordance with financial damage occurred is emerging. There is a potential risk factor not only from the case, the manufacturing to use the software company that appropriate to use a software business and personal risk of loss to size.In this paper due to diagnose and vulnerabilities in software, diagnosis, the curriculum and to cultivate a diagnostic guide, and security vulnerabilities in software.Proposal system for increased.

• Proceedings of the Korean Society of Computer Information Conference
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• 2023.07a
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• pp.629-630
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• 2023

최근 아파트의 월패드 해킹 사건과 같이 사물인터넷의 보안이 매우 심각한 상황이다. 사물인터넷은 자동화된 데이터 수집, 분석, 의사결정으로 효율성과 생산성 향상하고, 실시간으로 모니터링이 가능하면서 저비용으로 개발이 가능하다. 그리고 현재 인공 지능, 빅 데이터 및 클라우드 컴퓨팅 등 다양한 기술과 융합이 가능해 더욱 발전할 전망을 가지고 있다. 그러나 활용 범위가 갈수록 방대해지지만 현재 기술력으론 완벽한 보안을 실현하기가 어려운 것이 현실이다. 그리고 해킹의 대부분 직접적인 피해 당사자인 소비자들은 스마트홈이 주는 편의에 대해서만 알 뿐 보안 위협요소에는 잘 알지 못한다. 스마트홈의 보급이 빨라지고 있지만 정부 및 제조사에서 아직 스마트홈 보안에 관련한 홍보 및 교육이 따라가지 못하기 때문이다. 이러한 점을 보완하기 위해 본 논문에선 스마트홈의 보안 실태와 보안 요구사항에 대해서 다양한 방안을 살펴보고자 한다.

• Journal of the Korean Society of Hazard Mitigation
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• v.7 no.4
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• pp.1-12
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• 2007

A method for assessing fatigue vulnerability of steel bridge members considering corrosion and truck traffic variation with time is proposed to evaluate the reduction of fatigue strength in steel bridge members. A fatigue limit state function including corrosion and traffic variation effect is established. The interaction between the average corrosion depth and the fatigue strength reduction factor is applied to the limit state function as the reduction term of strength. Three types of truck traffic change is modeled for representing real traffic change trend. Monte-Carlo simulation method is used for reliability analysis which provides the data to obtain fatigue vulnerability curves. The estimation method proposed was verified by comparing with the results of reference study and applying to the steel bridges in service.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.5
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• pp.679-686
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• 2020

In this study, the seismic vulnerability of public river levees was analyzed quantitatively. Input seismic waves were generated in Pohang seismic waves in return periods of 200, 500, 1000, and 2400 years. The behavior of the levee was analyzed by seismic vulnerability analysis according to the return period. The displacement that occurs during an earthquake showed the same tendency as the input seismic wave and was largest in the return period of 2400 years. An analysis of the sliding stability revealed a 31.5% and 26.7% decrease in the sliding safety factor for the return period of 2400 for the landside and waterside, respectively. An examination of liquefaction by the q/p' ratio showed that the seepage line inside the embankment rises due to earthquakes. As a result, in the case of a return period of 2400 years, most embankments generate liquefaction, making them vulnerable to earthquakes. Through this research, it will be necessary to re-establish domestic seismic-design standards and establish clear standards for the results through a dynamics method.

• The Journal of Society for e-Business Studies
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• v.20 no.2
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• pp.125-140
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• 2015

It is general that the impact of supply chain risk spread out to the whole network along the connected structure. Due to the risk propagation the probability to exposure a certain risk is affected by not only the characteristics of each risk factor but also network structure. It means that the structural connectivity among vertices should be considered while designing supply chain network in order to minimize disruption cost. In this research, the betweenness centrality has been utilized to quantitatively assess the structural vulnerability. The betweenness centrality is interpreted as the index which can express both the probability of risk occurrence and propagation of risk impact. With the structural vulnerability index, it is possible to compare the stability of each alternative supply chain structure and choose the better one.

• Korean journal of food and cookery science
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• v.32 no.1
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• pp.136-146
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• 2016

The purpose of this study was to investigate whether there was a gender difference in motivating university students to decrease their sodium intake and to identify effective motivating factors. Within the protection motivation theory (PMT) framework, a survey questionnaire was developed to measure participants' perceptions on the severity of and the vulnerability to risk of serious diseases due to the high sodium intake, as well as the effectiveness (response efficacy) and the ability to perform preventive measures (self-efficacy). Behavioral intentions on five specific practices (checking nutrition label, consuming more fruits and vegetables, consuming less soups, avoiding spicy and pungent food, purchasing less instant or restaurant foods) related to decreasing sodium intake were also included. A total of 294 usable response data were collected from university students (92 male, 202 female) in Busan and Gyeongnam in June 2015 and analyzed using IBM SPSS 22. Severity was the highest (4.04) PMT factor followed by response efficacy (3.72), self-efficacy (3.42), and vulnerability (3.26). Compared to male students, female students thought that the threat was more severe (t=6.035, p<0.001) and reducing sodium intake would be effective to prevent serious illnesses (t=4.724, p<0.001), but their vulnerability and self-efficacy perceptions were not different from male students. Among the five items measuring behavioral intention, female students were more likely to increase fruits and vegetables consumption (t=3.811, p<0.001), while male students were more likely to avoid spicy and pungent foods (t=2.336, p=0.020). Based on findings of this study, the recommended strategy to effectively motivate university students to lower their sodium consumption level is the development of campaign focused on increased vulnerability perception, response efficacy, and ease of practicing preventive measures instead of emphasizing the severity of the consequences.

• Korean Journal of Social Welfare Studies
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• v.45 no.2
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• pp.233-261
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• 2014

There are two competing models explaining the causal relationship of depression and self-esteem, and they are cognitive vulnerability model and the scar model. Cognitive vulnerability model explains that low self-esteem poses as a risk factor for development of depressive symptoms/depression while the scar model asserts that the experiences of depression scars the cognitive function of individuals, resulting in negative self-perception. This study was set out to test two models on Korean adults, and to identify factors that are associated with depression and self-esteem relationship. The first four waves (wave 1~4) of the Korea Welfare Panel Study (KOWEPS) were used for analyses, and latent growth curve modeling was employed to examine the relationship. The findings show that the relationship was reciprocal, one affecting the growth trajectory of another over a four year period. Furthermore, education, poverty status, health status, and satisfaction with social relationships were found to be significantly associated with both depression and self-esteem trajectories. Implications for practice and theory are provided.

• Korean Journal of Culture and Social Issue
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• v.12 no.1
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• pp.15-33
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• 2006

There are less studies on the adult suicide even though it's steep increase and negative effect on person itself, family and society. The purpose of the present study was to investigate factors that influence on the adult suicide and to categorize it. Using a case-study approach, a total of 61 cases were analyzed. Specifically, on the basis of the stress-vulnerability model, I scrutinized vulnerability factors(classified personal, family-environment, and social-environment factors) and precipitating events(classified personal, interpersonal events) influencing on the adult suicide. As the results of this study, adult suicide classified into 3 types, that is, 'risk type suicide', 'event-response type suicide', 'complex type'. And then I discussed the characteristics of the suicidal types and the method for reduction of adult suicide.