• Title/Summary/Keyword: volume changes

Search Result 2,319, Processing Time 0.034 seconds

Characterization and predictive value of volume changes of extremity and pelvis soft tissue sarcomas during radiation therapy prior to definitive wide excision

  • Gui, Chengcheng;Morris, Carol D.;Meyer, Christian F.;Levin, Adam S.;Frassica, Deborah A.;Deville, Curtiland;Terezakis, Stephanie A.
    • Radiation Oncology Journal
    • /
    • v.37 no.2
    • /
    • pp.117-126
    • /
    • 2019
  • Purpose: The purpose of this study was to characterize and evaluate the clinical significance of volume changes of soft tissue sarcomas during radiation therapy (RT), prior to definitive surgical resection. Materials and Methods: Patients with extremity or pelvis soft tissue sarcomas treated at our institution from 2013 to 2016 with RT prior to resection were identified retrospectively. Tumor volumes were measured using cone-beam computed tomography obtained daily during RT. Linear regression evaluated the linearity of volume changes. Kruskal-Wallis tests, Mann-Whitney U tests, and linear regression evaluated predictors of volume change. Logistic and Cox regression evaluated volume change as a predictor of resection margin status, histologic treatment response, and tumor recurrence. Results: Thirty-three patients were evaluated. Twenty-nine tumors were high grade. Prior to RT, median tumor volume was 189 mL (range, 7.2 to 4,885 mL). Sixteen tumors demonstrated significant linear volume changes during RT. Of these, 5 tumors increased and 11 decreased in volume. Myxoid liposarcoma (n = 5, 15%) predicted decreasing tumor volume (p = 0.0002). Sequential chemoradiation (n = 4, 12%) predicted increasing tumor volume (p = 0.008) and corresponded to longer times from diagnosis to RT (p = 0.01). Resection margins were positive in three cases. Five patients experienced local recurrence, and 7 experienced distant recurrence, at median 8.9 and 6.9 months post-resection, respectively. Volume changes did not predict resection margin status, local recurrence, or distant recurrence. Conclusion: Volume changes of pelvis and extremity soft tissue sarcomas followed linear trends during RT. Volume changes reflected histologic subtype and treatment characteristics but did not predict margin status or recurrence after resection.

Interfraction variation and dosimetric changes during image-guided radiation therapy in prostate cancer patients

  • Fuchs, Frederik;Habl, Gregor;Devecka, Michal;Kampfer, Severin;Combs, Stephanie E.;Kessel, Kerstin A.
    • Radiation Oncology Journal
    • /
    • v.37 no.2
    • /
    • pp.127-133
    • /
    • 2019
  • Purpose: The aim of this study was to identify volume changes and dose variations of rectum and bladder during radiation therapy in prostate cancer (PC) patients. Materials and Methods: We analyzed 20 patients with PC treated with helical tomotherapy. Daily image guidance was performed. We re-contoured the entire bladder and rectum including its contents as well as the organ walls on megavoltage computed tomography once a week. Dose variations were analyzed by means of Dmedian, Dmean, Dmax, V10 to V75, as well as the organs at risk (OAR) volume. Further, we investigated the correlation between volume changes and changes in Dmean of OAR. Results: During treatment, the rectal volume ranged from 62% to 223% of its initial volume, the bladder volume from 22% to 375%. The average Dmean ranged from 87% to 118% for the rectum and 58% to 160% for the bladder. The Pearson correlation coefficients between volume changes and corresponding changes in Dmean were -0.82 for the bladder and 0.52 for the rectum. The comparison of the dose wall histogram (DWH) and the dose volume histogram (DVH) showed that the DVH underestimates the percentage of the rectal and bladder volume exposed to the high dose region. Conclusion: Relevant variations in the volume of OAR and corresponding dose variations can be observed. For the bladder, an increase in the volume generally leads to lower doses; for the rectum, the correlation is weaker. Having demonstrated remarkable differences in the dose distribution of the DWH and the DVH, the use of DWHs should be considered.

Visual Evaluation according to Changes in Volume and Position of Peplums (페플럼의 위치와 양에 따른 시각적 평가)

  • Koo, Mi-Ran;Lee, Jung-Jin
    • Journal of the Korea Fashion and Costume Design Association
    • /
    • v.17 no.3
    • /
    • pp.61-71
    • /
    • 2015
  • In this study, visual evaluation was performed with changes in peplums design to provide data which can enhance wearing image effects at the production of peplums one-piece. According to changes in volume and position of peplums, a total of 9 stimulants were chosen. Then, they were evaluated using a seven-point rating scale against 50 fashion students. The data has been analyzed by Factor Analysis, ANOVA, $Scheff{\acute{e}}$'s Test and the MCA method. The results of the study are as follows : 1. According to factor analysis, the components of visual evaluation depending on the changes in volume and position variations of peplums were divided into four factors: elegance, individuality, upper body correction and upper body emphasis. 2. According to visual evaluation depending on changes in the position variations of peplum, 'high waist' and 'natural waist' revealed a significant difference in elegance, individuality and upper body correction. 'Low waist' was observed in all four positions. 3. According to visual evaluation depending on the changes in volume of peplums, a significant difference at $45^{\circ}$ was observed in except for elegance. Significant differences at $90^{\circ}$ and $180^{\circ}$ were observed in all four positions. 4. In terms of interactions over in volume and position variations of peplums, interaction effects were found in two factors.

  • PDF

Experimental Study on the Triaxial Compressive Behaviour of Unsaturated Soil (불포화토의 삼축압축거동에 관한 실험적 연구)

  • Kim, Young-Seok;Oka, Fusao;Cho, Sam-Deok
    • Proceedings of the Korean Geotechical Society Conference
    • /
    • 2006.03a
    • /
    • pp.1224-1227
    • /
    • 2006
  • It has been recognized unsaturated soil behaviour playing an important role in geomechanics. Up to now, only a few experimental data are available for the technical difficulties related to both volume changes and suction measurements. In this study, the volume changes of unsaturated compacted silty soil were monitored with proximeter (i.e. non-contactable transducer) during various triaxial compression tests, which gave a realistic estimation in the volume changes of unsaturated soil sample. The measurement of volume changes were performed with 0.5% of the maximum error under the axial strain ratio of less than 10%. The experimental results have revealed that the mechanical behaviour of unsaturated soil can be significantly affected by the matric suction. During the shearing processes, the level of maximum deviator stress under the initial suction pressure of 50kPa was higher than that under the initial suction pressure of 10kPa. On the other hand, the volume changes became smaller under the increase in the initial suction pressure.

  • PDF

Physiological Effect on Changes of the Surface Area and the Volume of Limb and Their Effective Measurements (하퇴부(下腿部)의 표면적(表面積) 및 체적변화(體積變化)의 생리적(生理的) 배경(背景)과 측정(測定)에 대(對)한 연구(硏究))

  • Han, Sang-Deok;Lee, Yeong-Suk
    • Journal of the Ergonomics Society of Korea
    • /
    • v.7 no.2
    • /
    • pp.15-21
    • /
    • 1988
  • Changes of the surface area and the volume of limb are important factors for designing clothes and shoes. The limb volume increases slightly in the afternoon in general, because of human activity, as a diurnal variation. Changes are also associated with menstrual cycle, pregnancy, physical exercise and environmental temperature. The most effective method for measuring the surface area of limb is the paper replacement method.

  • PDF

Asymmetric Information Spillovers between Trading Volume and Price Changes in Malaysian Futures Market

  • Go, You-How;Lau, Wee-Yeap
    • The Journal of Asian Finance, Economics and Business
    • /
    • v.1 no.3
    • /
    • pp.5-16
    • /
    • 2014
  • This study aims to examine the dynamics of price changes and trading volume of Kuala Lumpur Options and Financial Futures Exchange (KLOFFE) from 2000 to 2008. With augmented analysis, our results support two hypotheses. First, under information spillover, our findings support noise traders' hypothesis as the time span for variance of past trading volume to cause variance of current return is found to be asymmetric under bull and bear markets. Second, looking at the dynamic relation between volume and volatility of price changes, our findings support Liquidity-Driven Trade hypothesis as past trading volume and subsequent volatility of return exhibit positive correlation. In terms of investors' behavior in response to the news, we find that investors are more risk taking in bull market and more risk reverse in bear market. Our study suggests that investors should adjust their strategy in the futures market in a dynamic manner as the time span of new information arrival is not consistent. Also, uninformed investors with information asymmetry should expect noninformational trading from informed investors to establish their desired positions for better liquid position.

A Study on Optical Properties in Biological Tissue Using A Photon Path Diffusion Model (광 항적경로 모델을 이용한 피하조직에서의 광 특성에 관한 연구)

  • 임현수
    • Journal of Biomedical Engineering Research
    • /
    • v.15 no.3
    • /
    • pp.265-274
    • /
    • 1994
  • This paper proposes a method of noninvasive reflectance light to measure the blood fractional volume (Vb) and oxygen saturation ($SO_2$) of biological tissue. We chose the red light of 660nm and infrared light of 880nm. In Vivo reflectance data were obtained by the physiological changes front the surface of the skin over the calf in human subject. The reflected light intensity from different layers within a biological tissue was measured by specially designed reflectometer to apply photon path diffusion model. The collected data represent the changes of blood (ractional volume and oxygen saturation at each reflected light wavelengths. The data evaluation was assessed by examining the slopes of the plotted indices for the changes in oxygen saturation and blood (ractional volume. The results presented in this paper claim that light reflectance can separately discriminate the change of blood volume and that of oxygenation in muscle and also in skin.

  • PDF

CHANGES IN HYOID BONE AND TONGUE POSITIONS, AND ORAL CAVITY VOLUME AFTER MANDIBULAR SETBACK BY SAGITTAL SPLIT RAMUS OSTEOTOMY

  • Liang, Shan-Shan;Chu, Yeon-Gyu;Choi, So-Young;Lee, Sang-Han;Park, In-Suk;Deng, Fang-Cheng
    • Maxillofacial Plastic and Reconstructive Surgery
    • /
    • v.31 no.4
    • /
    • pp.294-305
    • /
    • 2009
  • Purpose: This retrospective study evaluated the changes in hyoid bone and tongue positions as well as oral cavity volume after mandibular setback by BSSRO. Materials and Methods: 18 Koreans who underwent BSSRO to correct mandibular prognathism were studied. Lateral cephalograms were taken and traced preoperatively (T0), immediately (T1) and approximately 6 months postoperatively (T2). Submentovertex radiograghs were taken and traced before surgery (T0) and about 6 months after surgery (T2). The area and volume of oral cavity, the vertical and horizontal dimensions of the hyoid bone and tongue dorsum were measured. Results: Mandibular setback surgery resulted in a significant reduction of lower oral cavity volume. The hyoid bone displaced posteroinferiorly immediately after surgery, and it tended to return to its original vertical position at 6 month after mandibular setback by BSSRO. The retropalatal space around tongue was maintained and the retrolingual space around tongue was reduced immediately postoperatively. The readaptation of tongue was not evident for that the follow up period was not long enough. No significant statistical correlations between the amounts of mandibular setback and the changes of oral cavity volume were observed. Conclusion: Mandibular setback surgery resulted in a significant reduction of lower oral cavity volume, which was most likely attributable to the posterior movement of the mandible. More subjects and long-term observations should be performed to assess the changes of oropharyngeal configuration following mandibular setback surgery.

Silhouette Changes in Bell Bottom Pants and Visual Evaluation (벨보텀 팬츠의 실루엣 변화와 시각적 평가)

  • Cho, Eunhye;Lee, Young ju
    • Journal of the Korea Fashion and Costume Design Association
    • /
    • v.19 no.1
    • /
    • pp.91-105
    • /
    • 2017
  • A literature review and survey were conducted regarding the silhouette changes in bell bottom pants and the overall visual evaluation in accordance with the changes. The survey was disseminated from December 2015 to January 2016 to 245 women in their 20s living in Busan. The variables used for the silhouette changes in bell bottom pants were the volume of flare and the flare's starting point, and 20 pairs of terms were selected for visual evaluation. The results of the study are as follows: 1. Visual evaluations according to the volume of flare in bell bottoms indicated that females in their 20s appraised pants with a flare volume of 54 cm close to a straight silhouette and flare volume of 62 cm (recognized clearly as characteristic of bell bottom pants) to be more attractive and sophisticated than pants with flare volumes of 70 cm and 78 cm. 2.Visual evaluations according to the starting point of the flare in bell bottom pants showed that women appraised their legs as looking thinner when the flare started near the thighs. In a vertical visual evaluation, women appraised that their legs looked longer when the flare started near the knees and pants fit tightly around them. 3.The analysis of silhouette factors affecting the visual evaluation of bell bottom pants indicated that the volume of flare has more effect visually than the starting point of the flare.

  • PDF

Analysis of Difference in Growing Stock Volume Estimates by the Changes of Cluster Plot Design and Volume Equation (표본점 설계방법과 적용 단목재적식 변경에 따른 임목축적 차이의 구명)

  • Han, Won-Sung;Kim, Sung-Ho;Kim, Chong-Chan;Shin, Man-Yong
    • Journal of Korean Society of Forest Science
    • /
    • v.99 no.3
    • /
    • pp.304-311
    • /
    • 2010
  • Korea National Forest Inventory System has been adopting different cluster plot design and new equations to estimate growing stock volumes since 2006. These changes have resulted in volume estimations which show some difference from previous ones. This study is to find out the source of such difference. For this, relevant data was collected from 80 plots of 20 cluster samples according to the cluster plot design applied to 4th and 5th National Forest Inventory. Then growing stock volumes were estimated by using current and previous individual tree volume equations respectively. An investigation was made to detect whether such difference in volume estimates was originated from the changes in cluster plot design or from using different volume equations. T-test results showed that the difference from changes in cluster plot design was negligible. Instead, changes in volume equations had statistically significant effects in volume estimation. Since the volume estimation by the 5th National Forest Inventory would bring overestimation by applying different volume equations, all the volume estimations made prior to 2006 would require necessary modifications for international reporting.