• ETRI Journal
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• v.37 no.1
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• pp.97-106
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• 2015

In this paper, MOS-triggered silicon-controlled rectifier (SCR)-based electrostatic discharge (ESD) protection circuits for mobile application in 3.3 V I/O and SCR-based ESD protection circuits with floating N+/P+ diffusion regions for inverter and light-emitting diode driver applications in 20 V power clamps were designed. The breakdown voltage is induced by a grounded-gate NMOS (ggNMOS) in the MOS-triggered SCR-based ESD protection circuit for 3.3 V I/O. This lowers the breakdown voltage of the SCR by providing a trigger current to the P-well of the SCR. However, the operation resistance is increased compared to SCR, because additional diffusion regions increase the overall resistance of the protection circuit. To overcome this problem, the number of ggNMOS fingers was increased. The ESD protection circuit for the power clamp application at 20 V had a breakdown voltage of 23 V; the product of a high holding voltage by the N+/P+ floating diffusion region. The trigger voltage was improved by the partial insertion of a P-body to narrow the gap between the trigger and holding voltages. The ESD protection circuits for low- and high-voltage applications were designed using $0.18{\mu}m$ Bipolar-CMOS-DMOS technology, with $100{\mu}m$ width. Electrical characteristics and robustness are analyzed by a transmission line pulse measurement and an ESD pulse generator (ESS-6008).

• Proceedings of the KIPE Conference
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• 2004.07b
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• pp.551-555
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• 2004

The two-transformer full bridge (TTFB) PWM converter has two transformers which act as the output inductor as well as the main transformer, i.e. as the forward and the flyback transformer. Although the doubled leakage inductor of the TTFB makes it easier to achieve the zero-voltage switching (ZVS) of the lagging leg switch along the wide load range, it instigates a serious voltage ringing in the secondary rectifier diodes, which would require the dissipative snubber circuit, cause the serious power dissipation, and increase the voltage stress across those diodes. To overcome these problems, a, new lossless diode-clamp rectifier (LDCR) is employed as the output rectifier, which helps the voltage across rectifier diodes to be clamped on a half the output voltage $(V_o/2)$ or the output voltage $(V_o)$. Therefore, no dissipative snubber for rectifier diodes is needed and a high efficiency as well as low noise output voltage can be realized. The operations, analysis and design consideration of proposed converter are presented in this paper. To verify the validity of the proposed converter, experimental results from a 425W, 385-170Vdc prototype for the plasma display panel (PDP) sustaining power module (PSPM) are presented.

• The Korean Journal of Physiology and Pharmacology
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• v.22 no.6
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• pp.649-660
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• 2018

Migraine is a neurological disorder characterized by recurrent and disabling severe headaches. Although several anticonvulsant drugs that block voltagedependent $Na^+$ channels are widely used for migraine, far less is known about the therapeutic actions of carbamazepine on migraine. In the present study, therefore, we characterized the effects of carbamazepine on tetrodotoxin-resistant (TTX-R) $Na^+$ channels in acutely isolated rat dural afferent neurons, which were identified by the fluorescent dye DiI. The TTX-R $Na^+$ currents were measured in medium-sized DiIpositive neurons using the whole-cell patch clamp technique in the voltage-clamp mode. While carbamazepine had little effect on the peak amplitude of transient $Na^+$ currents, it strongly inhibited steady-state currents of transient as well as persistent $Na^+$ currents in a concentration-dependent manner. Carbamazepine had only minor effects on the voltage-activation relationship, the voltage-inactivation relationship, and the use-dependent inhibition of TTX-R $Na^+$ channels. However, carbamazepine changed the inactivation kinetics of TTX-R $Na^+$ channels, significantly accelerating the development of inactivation and delaying the recovery from inactivation. In the current-clamp mode, carbamazepine decreased the number of action potentials without changing the action potential threshold. Given that the sensitization of dural afferent neurons by inflammatory mediators triggers acute migraine headaches and that inflammatory mediators potentiate TTX-R $Na^+$ currents, the present results suggest that carbamazepine may be useful for the treatment of migraine headaches.

• The Korean Journal of Physiology and Pharmacology
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• v.7 no.1
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• pp.47-52
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• 2003

The prostate gland contains numerous neuroendocrine cells that are believed to influence the function of the prostate gland. Our recent study demonstrated the expression of both ${\alpha}1$- and ${\alpha}2$-ARs, signaling the release of stored $Ca^{2+}$ and the inhibition of N-type $Ca^{2+}$ channels, respectively, in rat prostate neuroendocrine cells (RPNECs). In this study, the effects of NA on the resting membrane potential (RMP) of RPNECs were investigated using a whole-cell patch clamp method. Fresh RPNECs were dissociated from the ventral lobe of rat prostate and identified from its characteristic shape; round or oval shape with dark cytoplasm. Under zero-current clamp conditions with KCl pipette solution, the resting membrane potential (RMP) of RPNECs was between -35 mV and -85 mV. In those RPNECs with relatively hyperpolarized RMP (＜-60 mV), the application of noradrenaline (NA, $1{\mu}M$) depolarized the membrane to around -40 mV. In contrast, the RPNECs with relatively depolarized RMP (＞-45 mV) showed a transient hyperpolarization and subsequent fluctuation at around -40 mV on application of NA. Under voltage clamp conditions (holding voltage, -40 mV) with CsCl pipette solution, NA evoked a slight inward current (＜-20 pA). NA induced a sharp increase of cytosolic $Ca^{2+}$ concentration ($[Ca^{2+}]_c$), measured by the fura-2 fluorescence, and the voltage clamp study showed the presence of charybdotoxin-sensitive $Ca^{2+}$-activated $K^+$ currents. In summary, adrenergic stimulation induced either depolarization or hyperpolarization of RPNECs, depending on the initial level of RMP. The inward current evoked by NA and the $Ca^{2+}$-activated $K^+$ current might partly explain the depolarization and hyperpolarization, respectively.

• Proceedings of the KIPE Conference
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• 1997.07a
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• pp.247-250
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• 1997

A novel zero-voltage-switching(ZVS) isolated PWM converter for single stage power factor correction (PFC) is presented to improve the performance of the previously presented ZVT converter[5]. A simple clamp circuit in the primary side provides zero-voltage-switching condition to all semiconductor devices. This ZVS is achieved with minimum device voltage and current stresses. Operation principle, control strategy and features of the proposed converter are presented and verified by the experimental results from a 1.5 ㎾, 100 KHz laboratory prototype

• Proceedings of the KIEE Conference
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• 2009.07a
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• pp.965_966
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• 2009

In this paper, a new soft-switching Two-switch Forward converter topology has been proposed. Compared with conventional two-switch forward converter, the proposed converter employs an auxiliary switch and a clamp capacitor to instead of two reset diodes, not only its duty cycle can exceed 0.5 to achieve wide range input voltage, but also soft switching can be achieved for all switches. Especially, voltage stress across main switches can be clamped at $1/2V_{in}$, voltage stress across auxiliary switch can be clamped at $V_{in}$. In addition, due to clamp capacitor series with the transformer, duty ratio can be extended with equation $V_o=\frac{V_{in}(1-D}D{N}$. Therefore, as a kind of better cost-effective approach, it is very attractive for high input, wide range and high efficiency application.

• Proceedings of the KIPE Conference
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• 2003.07a
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• pp.73-76
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• 2003

A zero voltage soft switching inverter using active clamp is presented for induction heating application. This converter have long been attractive because of its simplicity, high efficiency, and low cost compared to other schemes. In addition to those merits, Input power factor can be improved with a variable frequency control. In this paper, it describe the control method and operational principle to improve a power factor with a single stage US converter using active clamp for induction heating application.

• Proceedings of the KIEE Conference
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• 1993.11a
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• pp.110-113
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• 1993

The MOSFET synchronous rectification in the Active-Clamp Forward converter is presented. The Active-Clamp Forward converter has little dead time during the off time of the main switch and it is suitable for the MOSFET synchronous rectification comparing to the other Forward converter topologics. Using the MOSFET synchronous rectification on the Active-Clamp Forward converter with 3.3[V] output and 500[kHz] switching frequency, the improvement of efficiency is achieved comparing with the conventional Schottky barrier diode rectification.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.24 no.5
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• pp.136-144
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• 2010

This paper presents the two-switch interleaved active clamp forward converter, which is mainly composed of two active clamp forward converters. Only two switches are required, and each one is the auxiliary switch for the other. So, the circuit complexity and cost are reduced and control is more simple. An additional resonant inductance is employed to achieve ZVS(Zero-Voltage-Switching) during the dead times. Interleaved output inductor currents diminish the voltage and current ripple. Accordingly, the smaller output filter and capacitors lower the converter volume. This research proposed the Two-switch interleaved Active Clamp Forward Converter characteristic. The principle of operation, feature and design considerations is illustrated and the validity of verified through the experiment with a 160[W] based experimental circuit.

• The Korean Journal of Physiology and Pharmacology
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• v.11 no.1
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• pp.15-20
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• 2007

To investigate whether hydrogen peroxide($H_2O_2$) affects intestinal motility, pacemaker currents and membrane potential were recorded in cultured interstitial cells of Cajal(ICC) from murine small intestine by using a whole-cell patch clamp. In whole cell patch technique at $30^{\circ}C$, ICC generated spontaneous pacemaker potential under current clamp mode(I=0) and inward currents(pacemaker currents) under voltage clamp mode at a holding potential of -70 mV. When ICC were treated with $H_2O_2$ in ICC, $H_2O_2$ hyperpolarized the membrane potential under currents clamp mode and decreased both the frequency and amplitude of pacemaker currents and increased the resting currents in outward direction under voltage clamp mode. Also, $H_2O_2$ inhibited the pacemaker currents in a dose-dependent manner. Because the properties of $H_2O_2$ action on pacemaker currents were same as the effects of pinacidil(ATP-sensitive $K^+$ channels opener), we tested the effects of glibenclamide(ATP-sensitive $K^+$ channels blocker) on $H_2O_2$ action in ICC, and found that the effects of $H_2O_2$ on pacemaker currents were blocked by co- or pre- treatment of glibenclamide. These results suggest that $H_2O_2$ inhibits pacemaker currents of ICC by activating ATP-sensitive $K^+$ channels.