• Phonetics and Speech Sciences
• /
• v.8 no.3
• /
• pp.39-49
• /
• 2016

The present study examined the change of aerodynamic features after laryngomicrosurgery in patients with vocal polyps. Aerodynamic evaluation was performed in thirty-nine patients (15 males and 24 females) one week before surgery and four weeks after surgery. Evaluation protocols of vital capacity, maximum sustained phonation(MXPH), and voicing efficiency(VOFT) were used to collect 29 phonatory aerodynamic measures, requiring voice with a comfortable pitch and loudness. Statistically significant changes were found for phonation time and airflow values in the MXPH protocol, while changes were also found for airflow values, subglottal pressure values and acoustic resistance values in the VOFT protocol. Although phonation time was increased in both male and female patients, gender-dependent changes were found in airflow measurements. Men's phonation time increased with no difference in airflow rate, but women's phonation time increased with decreased airflow rate and lower subglottal pressure. The changes of aerodynamic features may be affected by women's self-perceived change for vocal attitude, which was reducing sense of vocal effort after surgery.

• Journal of applied mathematics & informatics
• /
• v.29 no.1_2
• /
• pp.427-442
• /
• 2011

Calcium is a vital second messenger for signal transduction in neurons. Calcium plays an important role in almost every part of the human body but in neuronal cytosol, it is of utmost importance. In order to understand the calcium signaling mechanism in a better way a finite element model has been developed to study the flow of calcium in two dimensions with time. This model assumes EBA (Excess Buffering Approximation), incorporating all the important parameters like time, association rate, influx, buffer concentration, diffusion constant etc. Finite element method is used to obtain calcium concentration in two dimensions and numerical integration is used to compute effect of time over 2-D Calcium profile. Comparative study of calcium signaling in two dimensions with time is done with other important physiological parameters. A MATLAB program has been developed for the entire problem and simulated on an x64 machine to compute the numerical results.

• The Transactions of the Korean Institute of Electrical Engineers D
• /
• v.55 no.3
• /
• pp.138-141
• /
• 2006

Blood flow is one of vital signals related to human physiological information. Photoplethysmograph (PPG) has been used to measure indirectly heart rate, blood oxygen saturation ($SpO_2$), and so on. Because PPG signal is weak and sensitive to motion artifacts, it is very important to continuously obtain stable PPG signal during free movement. In this study, we applied the scaled Fourier linear combiner (SFLC) using both the adaptive filter and FLC to remove effectively the motion artifacts as well as background noise in the real time without additional signal correlated with motion from a accelerometer. The proposed method would be useful to reduce the movement and background noise which are not synchronized with heart rate.

• Korean Journal of Bronchoesophagology
• /
• v.3 no.2
• /
• pp.270-276
• /
• 1997

The records of 18 patients with squamous cell carcinoma of the tongue and floor of mouth treated surgically were reviewed. Surgical approaches, staging, treatment modalities, recurrence and vital status were evaluated. The distrubutions of involved sites were tongue(9 cases) and mouth floor(9 cases). Patients were treated by surgery primarily, combined chemotherapy and radiation, and by surgical salvage in the failure cases of radiation and chemotherapy. All ipsilateral necks of mouth floor cancer and advanced tongue cancer were treated with neck dissection. Cases of early tongue cancer could be excised with transoral route, and advanced cases needed transmandibular approach. Whereas, majorites of mouth floor cancer needed transmandibular approach, and other cases could be excised transoral and pull-through approaches. In the recontructions, we used primary closure, pectoralis major myocutaneous flap, forearm free flap, fibular osteocutaneous flap and skin graft. One year survival rate was 93% and 2 year survival rate was 60%.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.16 no.1
• /
• pp.173-187
• /
• 2022

Recent studies have focused on self-management of hypertension using smart devices (cellular phones, tablets, watches). It has proven to be an effective tool for early detection and control of high Blood Pressure (BP) without affecting patients' daily routines. This systematic review surveys the existing self-monitoring systems, evaluate their effectiveness and compares the different approaches. We investigated the current systems in terms of various attributes, including methods used, sample size, type of investigation, inputs/ outputs, rate of success in controlling BP, group of users with higher response rate and beneficiaries, acceptability, and adherence to the system. We identified some limitations, shortcomings, and gaps in the research conducted recently studying the impact of mobile technology on managing hypertension. These shortcomings can generate future research opportunities and enable it to become more realistic and adaptive. We recommended including more observable factors and human behaviors that affect BP. Furthermore, we suggested that vital monitoring/logging and medication tuning are insufficient to improve hypertension control. There is also a need to observe and alter patient behavior and lifestyles.

• The Korean Journal of Physiology
• /
• v.9 no.2
• /
• pp.7-15
• /
• 1975

The maximum breathing capacity (MBC) and the maximum mid-expiratory flow rate (MMF) are widely used in evaluation of the ventilatory function, among various parameters of pulmonary function. The MBC volume is the amount of gas which can be exchanged per unit time during maximal voluntary hyperventilation. Performance of this test, unlike that of single breath maneuvers, is affected by the integrity of the respiratory bellows as a whole including such factors are respiratory muscle blood supply, fatigue, and progressive trapping of air. Because of this, the MBC and its relation to ventilatory requirement correlates more closely with subjective dyspnea than does any other test. The MMF is the average flow rate during expiration of the middle 50% of the vital capacity. The MMF is a measurement of a fast vital capacity related to the time required for the maneuver and the MMF relates much better to other dynamic tests of ventilatory function and to dyspnea than total vital capacity, because the MMF reflects the effective volume, or gas per unit of time. Therefore, it is important to have a prediction formula with one can compute the normal value for the subject and the compare with the measured value. However, the formulas for prediction of both MBC and MMF of the Korean children and adolescents are not yet available in the present. Hence, present investigation was attempt to derive the formulas for prediction of both MBC and MMF of the Korean children and adolescents. MBC and MMF were measured in 1,037 healthy Korean children and adolescents (1,035 male and 1,002 female) whose ages ranged from 8 to 18 years. A spirometer (9L, Collins) was used for the measurement of MBC and MMF. Both MBC and MMF were measured 3times in a standing position and the highest values were used. For measurement, the $CO_2$ absorber and sadd valve were removed from the spirometer in order to reduce the resistance in the breathing circuit and the subject was asked to breathe as fast and deeply as possible for 12 seconds in MBC and to exhale completely as fast as possible after maximum inspiration for MMF. During the measurement, investigator stood by the subject to give a constant encouragement. All the measured values were subsequently converted to values at BTPS. The formulas for MBC and MMF were derived by a manner similar to those for Baldwin et al (1949) and Im (1965) as function of age and BSA or age and height. The prediction formulas for MBC (L/min, BTPS) and MMF (L/min, BTPS) of the Korean children and adolescents as derived in this investigation are as follows: For male, MBC=[41.70+{$2.69{\times}Age(years)$}]${\times}BSA$ $(m^{2})$ MBC=[0.083+{$0.045{\times}Age(years)$}]${\times}Ht$ (cm) For female, MBC=[45.53+{$1.55{\times}Age(years)$}]${\times}BSA$ $(m^2)$ MBC=[0.189+{$0.029{\times}Age(years)$}]${\times}Ht$ (cm) For male, MMF= [0.544+{$0.066{\times}Age(years)$}]${\times}Ht$ (cm) For female, MMF=[0.416+{$0.064{\times}Age(years)$}]${\times}Ht$ (cm)

• Journal of Veterinary Clinics
• /
• v.27 no.4
• /
• pp.336-342
• /
• 2010

The purpose of this study was to determine the antagonistic effects of flumazenil on anesthesia induced with tiletamine/zolazepam in dogs. The anesthetic effects (sedation, analgesic, muscle relaxation, posture and auditory response score), vital signs (heart rate, respiratory rate and rectal temperature) and blood biochemistry (glucose (GLU), total protein (TP), alanine aminotransferase (ALT), aspartate aminotransferase (AST)) were examined as indicators of the antagonistic effects. A total of 6 clinically healthy mongrel dogs were used in this study. The dogs in TZ group received administration of tiletamine/zolazepam 10 mg/kg IV. The dogs in TZF group received administration dose of TZ 10 mg/ kg IV followed by the administration of flumazenil 0.1 mg/kg 20 minutes after administering a TZ 10 mg/kg dose. There were significant differences in the recovery of anesthesia between the groups. The GLU level in the TZF group after the administration of flumazenil was significantly higher than that of the TZ group. There was a larger change in the HR in the TZF group than in the TZ group until 30 minutes after flumazenil administration. The sternal recumbency, standing and walking times of the TZF group were faster than those of the TZ group. In conclusion, flumazenil showed antagonistic effect against tiletamine/zolazepam in dogs. When recovering from anesthesia, flumazenil reduced sternal recumbency, standing and walking times.

• Clinical and Experimental Pediatrics
• /
• v.54 no.11
• /
• pp.443-455
• /
• 2011

Neonatal mortality rate (NMR) or infant mortality rate (IMR) are the rate of deaths per 1,000 live births at which babies of either less than four weeks or of one year of age die, respectively. The NMR and IMR are commonly accepted as a measure of the general health and well-being of a population. Korea's NMR and IMR fell significantly between 1993 and 2009 from 6.6 and 9.9 to 1.7 and 3.2, respectively. Common causes of infantile death in 2008 had decreased compared with those in 1996 such as other disorders originating in the perinatal period, congenital malformation of the heart, bacterial sepsis of newborns, disorders related to length of gestation and fetal growth, intra-uterine hypoxia, birth asphyxia. However, some other causes are on the increase, such as respiratory distress of newborn, other respiratory conditions originating in the perinatal period, other congenital malformation, diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism. In this study, we provide basic data about changes of NMR and IMR and the causes of neonatal and infantile death from 1983 to 2009 in Korea.

• The KSFM Journal of Fluid Machinery
• /
• v.13 no.5
• /
• pp.11-16
• /
• 2010

The development of lifting pumps that lift minerals to a mining vessel are one of the vital parts of the commercial mining process. The purpose of this study is to investigate internal flow and its effect on the performance of a mixed flow pump in order to improve the pump's performance. Numerical analysis was performed by commercial code of ANSYS CFX-11 based on flow rate and length of flexible hose. The rated rotational speed of the impeller is 1750rpm. For taking into account the turbulence, k-$\omega$ SST model was selected to guarantee more accurate prediction of flow separation. The simulated results are in good agreement with the experimental results and showed that its efficiency and the head of the pump are related mainly to the flow rate and the length of flexible hose. A lesser flow rate caused more secondary flow through the guide vane passage. The length of flexible hose and flow rate exert much more influence on the pump's performance than the shape of the flexible hose.

• Journal of Sensor Science and Technology
• /
• v.17 no.6
• /
• pp.447-453
• /
• 2008

Respiration rate is one of the important vital signs. Photo-plethysmography (PPG) measurement especially on a finger has been widely used in pulse oximetry and also used in estimating respiration rate. It is well known that PPG contains respiration-induced intensity variation (RIIV) signal. However, the accuracy of finger PPG method has been controversial. We introduced a new technique of enhancing motion artifact by respiration. This was achieved simply by measuring PPG on the thorax. We examined the accuracy of these two PPG methods by comparing with two existing methods based on thoracic volume and nostril temperature changes. PPG sensing on finger tip, which is the most common site of measurement, produced 6.1 % error. On the other hand, our method of PPG sensing on the thorax achieved 0.4 % error which was a significant improvement. Finger PPG is sensitive to motion artifact and it is difficult to recover fully small respiratory signal buried in waveform dominated by absorption due to blood volume changes. Thorax PPG is poor to represent blood volumes changes since it contains substantial motion artifact due to respiration. Ironically, this inferior quality ensures higher accuracy in terms of respiration measurement. Extreme low-cost and small-sized LED/silicon detector and non-constrained reflection measurement provide a great candidate for respiration estimation in ubiquitous or personal health monitoring.