• 사상체질의학회지
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• 제26권4호
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• pp.379-388
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• 2014

Objectives The aim of this study was to report significant improvement of hyperhidrosis after treatment with Hyungbangsabaek-san (荊防瀉白散), in a Soyangin Mangeum Symptomatic pattern Patient. Methods The patients were diagnosed with Soyang Sin-Yeol Du-Tong Mang-Eum Symptomatology(身熱頭痛亡陰證) and treated with Hyungbangsabaek-san(荊防瀉白散). The primary outcome measure for this study were sweat using a questionnaire with visual analogue scale(VAS). Secondary outcome assessment included change of odinary symptoms such as patient's sleep, feces and digestion. Results The symptoms of hyperhidrosis disappeared by the end of the accure period without side effect. Original symptoms were also changed. Conclusions This result show Hyungbangsabaek-san(荊防瀉白散) can be used to treat hyperhidrosis in a Soyangin Heat-related diarrhea accompanied by headache Mangeum(身熱頭痛亡陰) symptomatic pattern patient. Meaning and process of hyperhidrosis are different according to Sasang Constitutions.

• 사상체질의학회지
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• 제28권4호
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• pp.381-395
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• 2016

Objectives The aim of this study was to report improvements on the symptoms of Flushing for three soyangin female patients after using sasang constitutional medicines. Methods The patients were diagnosed with Soyangin Symptomatology and treated with Soyangin sasang constitutional medicines. The patient's subjective symptoms of flushing and discomfort in sleeping were observed using the Visual Analogue Scale(VAS) respectively during the treatment period. And the patient's subjective symptoms of the pain were observed using Numerical Rating Scale(NRS). The period of the patient's defecation interval were also observed. Results and Concluions The symptoms of flushing, discomfort in sleeping and the pain improved remarkedly in all respects. In conclusion, this study shows that Sasang Constitutional Medicine can be an effective treatment for Soyangin patient with Flushing.

• 대한한방소아과학회지
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• 제37권4호
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• pp.63-69
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• 2023

Objective This study aimed to compare two cases of hyperhidrosis treated with herbal medicines. Methods This study included two children with hyperhidrosis who visited Pusan National University Korean Medicine Hospital. One patient was treated with Okbyungpoong-tang gagam and the other with Daeshiho-tang. Visual analog scale (VAS) scores for symptoms were evaluated before and after treatment. The characteristics, symptoms, and progression of treatment of each patient were evaluated and compared. Results After treatment, the patients showed a remarkable improvement in their main symptoms, and their constipation was relieved. Conclusion This case study showed that hyperhidrosis in two children improved significantly with herbal medicine. Furthermore, herbal medicine was effective in improving the accompanying symptoms, including constipation.

• 대한한방내과학회지
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• 제39권1호
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• pp.9-21
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• 2018

Objective: Graves' disease, the most common cause of primary hyperthyroidism, is a thyroid specific autoimmune disorder. When resistance to medication is shown in spite of long term therapy with anti-thyroid drugs, radioactive iodine therapy would be chosen in Western medicine. However, this therapy has often been reported to cause patients have hypothyroidism, thus requiring them to take levothyroxine for the rest of their lives. In this study, we evaluate the clinical efficacy and safety of Ahnjeonbaekho-tang (AJBHT) on patients with Graves' disease. Methods: We prescribed AJBHT for 3 months to two groups: patients who had been taking antithyroid drugs were administered AJBHT after discontinuing the antithyroid drugs ($Com-Tx{\rightarrow}Single-Tx$), and patients who had not been taking antithyroid drugs were started with AJBHT (Single-Tx) immediately. We evaluated the thyroidal function test (TFT) and visual analogue scale (VAS) for clinical symptoms for 3 months. Results: Serum T3 and fT4 were significantly decreased in both groups and remission rate of thyroidal hormones were significantly improved in the Single-Tx group. The clinical symptoms of palpitation, fatigue, and heat intolerance were significantly improved in both groups. In the safety analysis, all patients were in normal range of liver, renal function blood test and common blood count. Conclusion: From these results, we suggested that AJBHT was effective on TFT and clinical symptoms of Graves' disease. The study supports that AJBHT may be a useful agent for patients with Graves' disease who are resistant to antithyroid medication or radioactive iodine therapy, and for patients at first diagnosis.

• 동의생리병리학회지
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• 제30권1호
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• pp.66-72
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• 2016

This retrospective observational study was aimed to assess that Shinchubogun-tang (Shenzhuibujian-tang ; SBT) improves the symptoms related to lumbar disc herniation. We analyzed the medical records of 36 patients, who were satisfied with inclusion and exclusion criteria. The patients were diagnosed with lumbar disc herniation and prescribed with SBT in addition to Korean medical common treatments at Dunsan Korean Medicine Hospital of Daejeon University from January 1st, 2013 to November 30th, 2015. The effects of SBT was evaluated by comparing before and after taking SBT through 0-10 visual analogue scale(VAS) of the symptoms including lower back pain, radiating pain, and lower extremity numbness. The average period of common Korean medicine treatment before SBT prescription was 9.78 days and then the patients received SBT along with common Korean medicine treatment for 13.17 days on average. SBT plus common korean medicine treatment group significantly decreased VAS score of lower back pain from 5.40±1.62 to 3.28±1.70 (p<0.01), radiating pain from 5.60±1.42 to 2.35±1.79 (p<0.01), lower extremity numbness from 5.77±1.52 to 2.55±1.85(p<0.01). These results demonstrated that SBT might have a potential on improvement of lumbar disc herniation by reducing the symptoms of lower back pain, radiating pain, and lower extremity numbness.

• 대한후두음성언어의학회지
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• 제28권1호
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• pp.38-42
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• 2017

Background and Objectives : Globus pharyngeus is a sensation of foreign body in the throat. There are many studies evaluate relationships between globus pharyngeus and organic diseases such as laryngopharyngeal reflux, esophageal motility disorders as well as psychotic causes. But, Also many patients without etiologic causes complain of globus sensation. The authors performed a study that evaluate association between oral water intake and symptoms of globus sensation on the basis of a belief that pharyngeal dehydration due to lack of oral water intake causes globus sensation. Materials and Methods : A survey using visual analogue scale to evaluate symptoms was performed with 73 patients with globus pharyngeus. Results : Patients who drink water less than 500 mL per day (p=0.04) and less than five times per day (p=0.02) were improved after 6 months due to education and doctor's recommendation. Conclusion : Frequent and enough water intake should be recommended to resolve symptoms of globus sensation.

• Annals of Occupational and Environmental Medicine
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• 제35권
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• pp.1.1-1.11
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• 2023

Background: Although it is well known that the usage of visual display terminal (VDT) at the workplace causes computer vision syndrome (CVS), previous studies mainly focused on computer use and the health of white-collar workers. In this study, we explored the relationship between the usage of VDT including various devices, and symptoms related to CVS in a large population including pink-collar workers and blue-collar workers. Methods: 21,304 wage workers over the age of 20 years were analyzed from the 6th Korean Working Conditions Survey. To investigate the association between VDT use at work and symptoms related to CVS among wage workers, odds ratios (ORs) and 95% confidence interval (CI) were calculated by multivariate logistic regression models. Results: In the group with the highest VDT usage at work, the OR of headache/eyestrain was 2.16 (95% CI: 1.86-2.52). The OR of suspected CVS patients was significantly increased in the highest group of usage of VDT at work (OR: 1.69; 95% CI, 1.39-2.06). Compare with the reference group, the OR for headache/eyestrain in the highest group of VDT usage was 2.81 (95% CI: 2.13-3.70) in white-collar workers, 1.78 (95% CI: 1.32-2.40) in pink-collar workers, and 1.59 (95% CI: 1.18-2.15) in blue-collar workers. Conclusions: We observed a relationship in which the use of VDT in the workplace increases the risk of headache/eyestrain regardless of occupational classification. Our findings emphasize the importance of paying attention to the health of VDT workers and making plans to improve their working conditions.

• 생물정신의학
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• 제6권2호
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• pp.259-263
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• 1999

Nefazodone, a newer antidepressant is a phenylpiperazine derivative that inhibits the reuptake of both norepinephrine and serotonin, and antagonizes $5-HT_{2A}$ and ${\alpha}_1$ adrenergic receptors. Compared with SSRIs, nefazodone caused the fewer activating symptoms, adverse gastrointestinal effects(nausea, diarrhea, anorexia) and adverse effects of sexual function, but is associated with the more dizziness, dry mouth, constipation, visual disturbances and confusion. We report on 4 cases of visual disturbances and hallucinations in patients taking nefazodone. It is not certain what mechanisms mediated these side effects, but three mechanisms are possible. 1) Nefazodone, as a 5-HT2 antagonist, might induce visual disturbances. 2) mCPP, metabolite of nefazodone might contribute to the hallucination through action on 5-HT receptor. 3) Dopaminergic enhancing activity of nefazodone might cause hallucination. These case report raises the possibility that dose-related perceptual disturbances may exist with nefazodone. The fact emphasizes the need to pay close attention to all possible drug interactions, particularly in patients treated with multiple psychoactive agents, older patients, and patients with decreased hepatic function.

• Journal of Korean Neurosurgical Society
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• 제37권4호
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• pp.275-281
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• 2005

Objective: The prolactinoma is the most common pituitary tumor and sometimes shows severe invasiveness to the adjacent cavernous sinus, especially in the male patient. The dopamine agonist can be used as an alternative treatment modality to surgery. But, the transsphenoidal or transcranial approach for tumor removal has been more preferred treatment option of neurosurgeons in invasive prolactinoma. Especially rapid decompression of mass effect and resolution of the neurologic deficit is demanded. The prospective study is done in order to identify the therapeutic efficacy of bromocriptine as an initial treatment option for the invasive prolactionomas. Methods: Twenty patients with invasive prolactinoma were studied. Preoperative neurological and endocrinological evaluations were done, and size and invasiveness of the tumor was estimated on MRI. Bromocriptine was administrated by increasing dose planning reaching maximum dose at 1 month of treatment, with close neurological and endocrinological monitoring. At 3months after treatment, MRI was taken and decision was made whether to continue bromocriptine or to have surgical intervention. Results: Thirteen patients showed excellent result with only bromocriptine treatment. These patients showed not only marked reduction of tumor volume and prolactin level, but also, improving clinical symptoms and other hormonal deficits. 13patients who had visual field defect and decreased visual acuity had all improved visual symptoms. But, the remaining 4patients required surgical treatment due to insufficient reduction of tumor size inspite of normalized prolactin level within 3months. Remaining 2patients had $20{\sim}30%$ of tumor size reduction, but prolactin level was not normalized. One patient required radiation therapy. Conclusion: Bromociptine can be used as initial treatment for the invasive prolactinomas with careful monitoring of the neurological and endocrinological status. It should be carefully followed up for tumor size reduction within 3 months after initiation of treatment.

• 디지털융복합연구
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• 제16권10호
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• pp.531-536
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• 2018

본 연구는 젊은 성인에서 근업시간에 따른 눈 피로도의 정도를 파악하고, 시각적 불편함의 종류를 분석하였다. 평균 연령 25.37세의 347명(남 142명, 여 205명)을 대상으로 눈 피로도와 관련 요인에 대해 설문하였다. 눈 피로도는 Conlon 등이 개발한 시각적 불편함에 관한 설문 도구를 이용하였고, 근업시간은 일일 컴퓨터와 스마트폰 사용을 조사하였다. 대상자의 눈 피로도는 근업시간이 2시간미만, 2~4시간, 4~6시간, 그리고 6시간 이상일 때 각각 $13.65{\pm}7.11$점, $16.83{\pm}6.77$점, $18.88{\pm}6.60$점, 그리고 $18.83{\pm}5.62$점으로 증가하였다(p=0.001). 또한 근업시간에 따라 두통(p<0.030)과 함께 다시 읽기(p<0.036), 안구운동과 탈색(p<0.001)과 같은 시각활동에서 불편함을 느꼈다.