Proceedings of the Korean Environmental Health Society Conference
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2003.06a
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pp.157-157
/
2003
To evaluate an effect of pathological liver damage on the cyclohexane metabolism, rats were pretreated with 50% $CCl_4$ dissolved in olive oil (0.1$\mell$/100g body weight) 10 or 17 times intraperitoneally at intervals of every other day. On the basis of liver function and histological findings, the animals pretreated with $CCl_4$ 10 times were identified as acutely liver damaged ones and the animals pretreated with $CCl_4$ 17 times were identified as severly liver damaged ones, with fibrosis, biliary abnormality and mild injury both in the kidneys and the lungs. To these liver damaged animals, cyclohexane (a single dose of 1.56g/kg body weight, i.p.) was administrated at 48 hours after the last injection of $CCl_4$. The rats were sacrificed at 4 or 8 hours after injection of cyclohexane. The cyclohexane metabolites; cyclohexanol (CH-ol), cyclohexane-1, 2-diol (CH-1, 2-diol), cyclohexane-l, 4-diol (CH-1, 4-diol), and their glucuronyl conjugates and cyclohexanone (CH-one) were detected in the urine of cyclohexane treated rats. After cyclohexane treatment, the serum levels of CH-ol and CH-one were remarkably increased at 4 hours and then decreased at 8 hours in normal group. Whereas in liver damaged rats, these cyclohexane metabolites were higher at 8 hours than at 4 hours. The excretion rate of cyclohexane metabolites from serum into urine was more decreased in liver damaged animals than normal group, with the levels of excretion rate being lower in $CCl_4$ 17 times injected animals than 10 times injected ones. However, it was interesting that the urinary concentration of cyclohexane metabolites was generally more increased in liver damaged animals than normal ones, and the increasing rate was higher in $CCl_4$ 17 times injected rats than 10 times injected ones. And liver damaged rats, especially $CCl_4$ 17 times treated ones, had an enhanced ability of glucuronyl conjugation to cyclohexanol analogues compared with normal group. Futhermore, CH-1, 2 and 1, 4-diol were all conjugated with glucuronic acid in $CCl_4$ 17 times injected animals. In conclusion, the metabolic rate of cyclohexane was unexpectably accelerated and it may be caused by physiological adaptation of adjacent intact hepatocyte in damaged liver.
Journal of the Korean Society of Food Science and Nutrition
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v.34
no.9
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pp.1330-1335
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2005
Red brownish p-pheylenediamine (PPD) has been widely used hair dye for women. The dye was known to cause systemic anaphylaxis, dermatitis and bladder cancer. But the effect of PPD toxicity with oxygen free radical has not been studied. This study investigated the degree of skin injury by PPD. PPD ($2.5\%$ PPD in $2\%\;NH_{4}OH$) was applied to the rat skin ($25 mg/16.5\;cm^2$) 3 or 5 times every other day. Histopathological findings demonstrated the proliferation of epithelial cells and the increased keratinization by PPD. The activities of glucose 6-phosphatase (G6Pase) was decreased and acid phosphatase (ACP) was increased in PPD-applied rat skin. Groups in which PPD was applied 5 times were more damaged than groups applied 3 times. To examine the relationship between tissue damage and oxygen free radicals, effect of PPD on xanthine oxidase (XO) activity was measured and XO activity was more significantly increased in the group treated with PPD 5 times than 3 times. However, reduced glutathione (GSH) content, and the activities of catalase (CAT), super-oxide dismutase (SOD) and glutathione S -transferase (GST) were more decreased in PPD-applied groups than in controls. Even though the activities of XOD was not changed in the group treated with PPD 3 times, the decreased activities of oxygen free radical system and the damaged skin tissue were observed. This result might be caused by the production of toxic PPD metabolites in rat skin. In conclusion, topical PPD application led to skin injury in a dose-dependent manner, probably due to the generation rate of oxygen free radical.
Journal of the Korean Society of Environmental Restoration Technology
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v.6
no.5
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pp.40-47
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2003
This study examined the improved effect of wear tolerance of warm-season turfgrass overseeded with cool-season turfgrasses. Also, it investigated the improved effect of crumb rubber on wear tolerance and the difference anmong cultivars regarding the wear of Zoysia spp. In wear experiment during summer, the warm-season turfgrass overseed with cool-season turfgrasses had a higher visual rating on the ground than the monostand of Cynodon dactylon. Moreover, in wear experiment in winter, barrenness showed significant progress in the monostand of C. dactylon, while the barrenness did not appear at all in overseeded turf with cool-season turfgrasses. As a result of investigating the bulk density was increased in the monostand of C. dactylon, but not in the overseed turf with cool-season turfgrasses. From the above result, the wear tolerance effcect of turfgrasses appeared year round through warm-season and cool-season turfgrass mixtures. Also, it was found that the method of topdressing crumb rubber on the ground was effective as a physical assistant device alleviating damage of turfgrasses. The possibility of improving wear tolerance was accepted by adding soil amendments such as perlite, pamis, etc., in order to promote the growth of turfgrass.
This study investigated the development of a fire alarm system with evacuation lighting and voice alarm functions. The performance of a fire detector and system with independently built-in evacuation lighting and voice alarm functions was confirmed for early recognition of fire and to allow visibility of the evacuation route in the event of fire. This new system satisfied model recognition and product testing technological standards with 1.62 lx average illumination, 89.7 dB average sound and 86.1 dB average voice. From additionally testing the evacuation performance of this new system, it was confirmed that the evacuation time decreased by 63.08% to 67.82% under the experimental conditions compared to conventional systems. The new system can minimize fire damage by setting off voice alarms to prevent failure of fire recognition and by flashing emergency lighting to secure the minimum required visibility range for evacuation. Therefore, it is considered that it will be utilized as a fire alarm system with appropriateness and usefulness by considering people with hearing or visual impairment.
As greater numbers of fill dams and reservoirs become old, the risks of damage or embankment collapse increases. However, few studies have considered the deterioration and hazard classification of the internal core layers of fill dams. This study reports the results of geotechnical investigations of 13 earth-cored fill dams in Korea, based on no-water borehole drilling, Standard Penetration Test, and 2D and 3D electrical resistivity surveys along with in situ and laboratory testing. High-capacity no-water boring minimized core layer disturbance while providing continuous core sample recovery. The results allow the classification of potential hazards related to the existing core layers based on both visual inspection of the recovered samples and the results of engineering surveys and tests. Four types of potential hazard are classified: locally fluidized core with a high water content, rapid water inflow to a borehole, cores with granular materials, and relatively low stiffness of core. Among these, the locally fluidized core is the most critical hazard that requires remedial action because it is related to the potential internal flow path and internal erosion. The other three hazard types are of medium importance and require careful monitoring and regular inspection. Of note, there was no correlation between age and core deterioration. The results are expected to aid the safe management and potential upgrading of aging cored fill dams.
Journal of The Korean Society of Integrative Medicine
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v.3
no.4
/
pp.11-21
/
2015
Purpose : The purpose of this study was to provide the material about the treatment effect of hand function training and writing training being performed as a part of treatment to improve the function of the non-dominant hand of the patients whose dominant hand is damaged and thus need to improve their non-dominant hand's function. Method : During one month of November, 2013, this study randomly chose five study subjects for hand function training, five for writing training, and ten of control group from 20 normal male and female adults going to K Univ. in Busan. All study subjects fully understood all of the training course, agreed to take the test in this study, and volunteered to participate in the test. Each training was performed five times for two weeks, 30 minutes each time. For measurement, Purdue pegboard was used to look into the change of hand dexterity. To investigate an improvement in hand function through hand function training and writing training, this study conducted early evaluation before training, interim evaluation, and final evaluation. Result : First, according to the comparison of dominant hand dexterity by group and by method during a training period, the groups of hand function training and of writing training improved dominant hand dexterity more than the control group. Secondly, according to the comparison of non-dominant hand dexterity by group during a training period, the groups of hand function training and of writing training improved dexterity more than the control group. According to the comparison of non-dominant hand dexterity by method during a training period, there was no big difference in dexterity between the groups of hand function training and of writing training and the control group. But, the group of hand function training showed a further improvement. Thirdly, according to the comparison of both-hand dexterity by group and by method during a training period, the groups of hand function training and of writing training improved both-hand dexterity more than the control group. Fourthly, according to the comparison of both-hand handling ability by group and by method during a training period, the groups of hand function training and of writing training improved both-hand handling ability more than the control group. Conclusion : Given the study result, it is considered that hand function training and writing training help brain damaged patients improve their hand function for their daily activity. And it will be meaningful to research brain damaged patients' motor skills after their brain damage, and the patients who have low abilities of visual perception and cognition. In the future, it will be necessary to secure more study subjects and perform systematic training during a sufficient test period.
Park, Sung-Chul;Moon, Sung Woo;Kim, Sa-Duk;Jwa, Yong-Joo
The Journal of the Petrological Society of Korea
/
v.24
no.1
/
pp.11-24
/
2015
In this study, the stone used for three storied pagoda of Bulguksa Temple, which is easy to access due to works for dismantle and restore will be analyzed on the basis of petrographic study, magnetic susceptibility, and ${\gamma}$-ray spectrometer, and identify petrographic characteristics. Also we will select candidate areas of fresh rock to change the stone used for three storied stone pagoda as from its provenance is presumed. According to the results of visual inspection, the stones used for the three storied stone pagoda are similar to the features of Namsan granite, which is distributed around Gyeongju-si, and when it comes to the section of the stupa finial, the features of all the parts from the stupa finial is similar to Namsan granite except for the section of Jeweled cover. On the other hand, the color, the composition, and the mineral size of the stones in the section from the part of jeweled cover are similar to Tohamsan granite. As a result of none-destruction inspection, it seems that the stones used for the three stories stone pagoda except for the section of jeweled cover are similar to the values for the magnetic susceptibility and the ${\gamma}$-ray spectrometer. On the other hand, Jeweled cover and the values of Tohamsan granite are alike. Namsan granite is appropriate in case that the stone used for three storied stone pagoda must be replaced to fresh rock because of damage by weathering. Meanwhile, Namsan granite is seperated from Yangsan fault. Due to this fact, Namsan granite appears to not only Mt. Namsan in Gyeongju, but also Dongcheon-dong, Gyeongju, and Huenggok-ri, Pohang. As a result, these two areas are suitable to the candidate area to change the stone used for three storied stone pagoda.
Journal of the Korea institute for structural maintenance and inspection
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v.24
no.4
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pp.48-54
/
2020
Cracks in reinforced concrete structures are the most common type of damage and are used as important analytical data to understand the fracture behavior characteristics of structures. Currently, there is a problem that most of the crack investigation relies on visual inspection, therefore many researchers have proposed image analysis techniques to improve the problem. In this study, we proposed a crack evaluation method to be applied at an indoor experimental level using image analysis method. The image analysis technique using color is for distinguishing a boundary surface between objects existing in an image, and is a method for separating similar colors into one region based on a predefined color. In this study, to improve the accuracy of image analysis, blue paint was applied to the concrete surface and bending experiments were performed. The image analysis method was able to measure the crack width with superior accuracy compared to the crack diameter, and at the same time, it was also possible to analyze the deflection of the beam. Both the crack and deformation were able to confirm the accuracy similar to the existing measurement method, and it was found that the image analysis method was very excellent in terms of applicability.
It has been well known that concrete structures exposed to acid and sulfate environments such as sewer, sewage and wastewater, soil, groundwater, and seawater etc. show significant decrease in their durability due to chemical attack. Such deleterious acid and sulfate attacks lead to expansion and cracking in concrete, and thus, eventually result in damage to concrete matrix by forming expansive hydration products due to the reaction between portland cement hydration products and acid and sulfate ions. Objectives of this experimental research are to investigate the effect of mineral admixtures on the resistance to acid and sulfate attack in concrete and to suggest high-resistance concrete mix against acid and sulfate attack. For this purpose, concretes specimens with three types of cement (ordinary portland cement (OPC), binary blended cement (BBC), and ternary blended cement (TBC) composed of different types and proportions of admixtures) were prepared at water-biner ratios of 32% and 43%. The concrete specimens were immersed in fresh water, 5% sulfuric acid, 10% sodium sulfate, and 10% magnesium sulfate solutions for 28, 56, 91, 182, and 365 days, respectively. To evaluate the resistance to acid and sulfate for concrete specimens, visual appearance changes were observed and compressive strength ratios and mass change ratios were measured. It was observed from the test results that the resistance against sulfuric acid and sodium sulfate solutions of the concretes containing mineral admixtures were much better than that of OPC concrete, but in the case of magnesium sulfate solution the concretes containing mineral admixtures was less resistant than OPC concrete due to formation of magnesium silicate hydrate (M-S-H) which is non-cementitious.
Kim, Seong-Tae;Song, Min-Young;Kim, Dae-Hun;Lee, Eun-Ji;Kwon, Min-Goo;Sul, Jae-Uk;Kim, Sunjong;Bae, Giljun;Choi, Jin-Bong
Journal of Korean Medicine Rehabilitation
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v.25
no.1
/
pp.77-85
/
2015
This study analyzed the MMPI (Minnesota Multiphashic Personality Inventory), VAS (Visual Analogue Scale), cervical and lumbar curvature (Cervical angle, Ishihara Index, Lumbar angle, Ferguson angle) and satisfaction score of patient of traffic accident. About 59 cases of patients admitted to the Korean Medicine hospital, MMPI and pain levels (VAS) cervical and lumbar curvature (Cervical angle, Ishihara Index, lumbar angle, Ferguson angle) and satisfaction score were measured and statistically analyzed. Depending on the type of accident divided into two groups of In car TA and Out car TA. After hospitalization, patient's pain index was improved as a whole. Pain index and evaluation of the cervical and lumbar curvature, according to the accident types, the difference was not statistically significant. In the analysis of the MMPI validity scales, In car TA group was analyzed by 'V-shaped', Out car TA group was analyzed by umbrella- shaped, 'inverted V-shaped'. Clinical scales of out car TA group were analyzed by 3-1 profile compared to the In car TA group. Results of multiple regression analysis showed no association between factors and MMPI scales. In the case of a traffic accident patients, damage to the body, as well as emotional and psychological factors are thought to affect the condition or prognosis of patients. In the future, for the management and treatment of these parts will be needed to complement the academic or institutional.
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