• 한국산학기술학회논문지
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• 제12권12호
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• pp.5789-5796
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• 2011

본 연구는 왼쪽 하퇴삼두근의 원심성 운동으로 인한 지연성 근통증에서 진동훈련의 효과를 알아보고자 하였다. 이전에 규칙적인 하지 운동에 참여하지 않은 21명의 신체 건강한 남녀를 대상으로 진동훈련군과 대조군으로 나누었다. 통증척도, 발목 족저굴근의 근력, 하퇴삼두근의 둘레, 혈중 CK 수치를 원심성 운동전, 24시간, 48시간, 72시간 후에 측정하였다. 통증척도는 지연성 근통증 유발 후 48시 시점에 집단 간 유의한 차이를 보였고, 측정시기에 따라 집단 내 유의한 차이를 보였다(p<.05). 족저굴근의 근력은 진동훈련 집단 간의 유의한 차이는 보이지 않았으나, 측정시기에 따라 집단 내 유의한 차이를 보였다(p<.05). 하퇴삼두근 둘레는 진동훈련 집단 간 유의한 차이는 보이지 않았으나, 측정시기에 따라 집단 내 유의한 차이를 보였다(p<.05). 혈중 CK 수치는 진동훈련 집단 간에 유의한 차이는 보이지 않았으나, 측정시기에 따라 집단 내 유의한 차이를 보였다(p<.05). 본 연구결과로 원심성 운동 전 진동훈련은 통증을 억제하는 효과가 있으므로 익숙하지 않은 활동을 하거나, 스포츠 활동에서의 지연성 근통증을 예방하기 위한 한 방법으로 제시될 수 있을 것으로 사료된다.

• Journal of Pharmaceutical Investigation
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• 제29권3호
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• pp.217-225
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• 1999

These studies were designed to determine the effect of hydroalcoholic gel system (lower alkanol concentration: 40-60%) compared to general hydrogel system (lower alkanol concentration: 10-35%) on transdermal delivery of piroxicam and its anti-inflammatory activity. Piroxicam was incorporated into a hydroalcoholic gel and a hydrogel containing polymers, solvents, and cosolvents. The pH of gel was about 6.3-7.3 and the solvent mixtures were composed of water and various concentrations of ethanol (35, 40, 50, and 60%). For the in vitro study, the skin permeation of piroxicam from the gel formulations was investigated using Franz modified diffusion cells fitted with hairless mouse skin. For the in vivo study, the anti-inflammatory activity of hydroalcoholic gel was compared to other commercial products (piroxicam hydrogel and ketoprofen hydrogel) in rat and human. The anti-inflammatory activity was determined using carrageenan induced foot edema model in rat. For the clinical study, it was evaluated from determining efficacy and acceptability with 98 patients suffering from musculoskeletal pain. A novel piroxicam hydroalcoholic gel was successfully formulated in the range of 40-50% of ethanol as solvent, more than 10% of propylene glycol, 5% of $Transcutol^{\circledR}$ and 1 % of benzyl alcohol. The skin permeation of piroxicam using hydroalcoholic gel system was greater than that of general hydrogel system $(flux\;:\;139.1-148.2\;{\mu}g/cm^2/hr\;vs.43.0-84.5 {\mu}g/cm^2/hr)$ in vitro. In carrageenan-induced edema model, the anti-inflammatory activity of hydroalcoholic gel was better than that of piroxicam hydrogel for edema inhibition (75.1 % vs. 62.9%, p

• Clinics in Shoulder and Elbow
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• 제17권2호
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• pp.68-76
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• 2014

Background: Recently, reverse total shoulder arthroplasty (RTSA) has been accepted as a main treatment option in irreparable massive rotator cuff tear with cuff arthropathy. The purpose of this study was to evaluate the early complication incidence and the preliminary clinical results of RTSAs performed in single institute. Methods: Fifty-seven RTSAs (56 patients) were performed between April 2011 and March 2013. The indications for RTSA were cuff tear arthropathy and irreparable massive rotator cuff tear with or without pseudoparalysis. Exclusion criteria were revision, preoperative infections and fractures. At final follow-up, 45 shoulders were enrolled. Mean follow-up duration was 12.5 months (range, 6-27 months). The mean age at the time of surgery was 73.6 years (range, 58-87 years). All the patients were functionally accessed via Constant score, American Shoulder and Elbow Surgeons (ASES) score, pain and functional visual analogue scale (VAS) scores and active range of motion. Complications were documented as major and minor. Major complications include fractures, infections, dislocations, nerve palsies, aseptic loosening of humeral or glenoid components, or glenoid screw problems. Minor complications include radiographic scapular notching, hematomas, heterotopic ossification, algodystrophy, intraoperative dislocations, intraoperative cement extravasation, or radiographic lucent lines of the glenoid. Results: The mean Constant score increased from 31.4 to 53.8 (p < 0.001). The pain and functional VAS scores improved (5.2 to 2.7, p < 0.001, 4.0 to 6.7, p < 0.001) and active forward flexion improved from $96.9^{\circ}$ to $125.6^{\circ}$ (p = 0.011). One or more complications occurred in 16 (35.6%) of 45 shoulders, with one failure (2.2%) resulting in the removal of implants by late infection. The single most common complication was scapular notching (9 [20%]). There were 4 (8.9%) axillary nerve palsies postoperatively (n=3: transient n. palsy, n=1: Symptom existed at 11 months postoperatively but improving). Conclusions: In a sort term follow-up, RTSA provided substantial gain in overall function. Most common early complications were scapular notching and postoperative neuropathy. Although overall early complication rate was as high as reported by several authors, most of the complications can be observable without compromise to patients' clinical outcome. Long term follow-up is required to clarify the clinical result and overall complication rate.

• Clinics in Shoulder and Elbow
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• 제20권3호
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• pp.117-125
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• 2017

Background: To compare the clinical outcomes of arthroscopic capsular release in patients with and without inferior capsular release for shoulder stiffness. Methods: Between January 2010 and December 2015, 39 patients who underwent arthroscopic capsular release for shoulder stiffness were enrolled and randomized into two groups. In group I, 19 patients underwent arthroscopic capsular release of the rotator interval and anterior capsule. In group II, 20 patients underwent arthroscopic capsular release of the anterior to inferior capsule, including the rotator interval. The American Shoulder and Elbow Surgeons score, Constant scoring system, Simple Shoulder Test, visual analogue scale for pain, and range of motion (ROM) were used for evaluation before surgery, at 3, 6, and 12 months after surgery and on the last follow-up. Results: Preoperative demographic data revealed no significant differences (p>0.05). The average follow-up was 16.07 months. Both groups showed significantly increased ROM at the last follow-up compared with preoperative (p<0.05). At the last follow-up, no statistical differences were found (p>0.05) between groups I and II in functional scores and ROM (forward flexion, p=0.91; side external rotation, p=0.17; abduction external rotation, p=0.72; internal rotation, p=0.61). But we found that group II gained more flexion compared to group I at 3 months and 6 months (p<0.05) after the surgery. Conclusions: Both techniques of capsular release are effective for stiffness shoulder. However, the extended inferior capsular release shows superiority in forward flexion over anterior capsular release alone during 6 months of follows-up (level of evidence: Level I, therapeutic randomized controlled trial).

• 대한지역사회영양학회지
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• 제19권5호
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• pp.479-489
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• 2014

Objectives: This study intended to determine significant factors that influence the health-related quality of life ("HRQoL"; EuroQol 5 Dimension health-related quality of life (EQ_5D) & EuroQol visual analogue scale (EQ_VAS)) of the elderly in Korea. Methods: This study was based on 3,903 subjects aged 65 years or more who participated in the Fifth Korea National Health and Nutrition Examination Survey (KNHANES V), 2010~2012. The HRQoL was analyzed by various factors (general characteristics, health habits, mental health, chronic diseases, nutrient intakes). SPSS statistics for complex samples (Windows ver. 21.0) was used. Results: The HRQoL was higher in the males, those with higher educational level or higher income level while it was lower in those belong to single households. In particular, the EQ_5D was significantly higher in the group who reported walking practice, moderate physical activity (male), and the group who reported no vigorous physical activity (female). The EQ_VAS was significantly higher in the group who reported walking practice. Both EQ_5D and EQ_VAS were significantly lower in the group with stress, melancholy, suicidal thinking, and osteoarthritis. EQ_5D was significantly lower in the group with < 75% Estimated Energy Requirements (EER) in energy intake, and with < Estimated Average Requirements (EAR) in iron or niacin intake. A stepwise regression analysis revealed that i) higher educational level (male), and good self-rated health status significantly increased the EQ_5D, ii) age, alcohol intake (male), melancholy (female), suicidal thinking, osteoarthritis, and niacin intake deficiency (male) significantly decreased the EQ_5D, iii) higher income level (male) and good self-rated health status significantly increased the EQ_VAS, and iv) age (male), stress, suicidal thinking (female) and osteoarthritis significantly decreased the EQ_VAS. Conclusions: This study suggested that general characteristics, mental health, osteoarthritis, and niacin intake were associated with the HRQoL. Prospective research of long-term control is needed to establish the causal relationship between factors and the HRQoL.

• 한국산학기술학회논문지
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• 제17권5호
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• pp.522-529
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• 2016

본 연구는 전방십자인대 재건술을 시행한 환자를 대상으로 후방보행을 포함한 재활운동 프로그램이 환자의 통증지수와 ROM, 고유수용성감각에 어떠한 영향을 미치는지 구명하고자 하였다. 이 연구의 대상자는 전방십자인대 손상으로 재건술을 시행한 환자 14명으로 하였으며 후방보행 집단(n=7)과 통제집단(n=7)으로 무선배정 하였고 4주간 각각의 재활운동프로그램을 실시하였다. 이 연구의 결과에서, 굴곡 관절가동범위는 운동 전 후, 후방보행 집단(p<.001)과 통제집단(p<.01) 모두 운동 후 유의하게 감소되었으며 신전 관절가동범위에서는 후방보행 집단(p<.05)에서만 운동 후 유의한 차이를 나타내었고 두 변인 모두 집단 간의 차이는 보이지 않았다. 통증지수에 대한 결과에서는 운동 후, 두 집단 모두 유의하게 감소되었고(p<.001) 집단 간 차이에서는 운동 후, 후방보행 집단이 통제집단보다 유의하게 낮은 것으로 나타났으며(p<.001), 고유수용성감각에서는 후방보행 집단(p<.001)과 통제집단(p<.05) 모두 운동 후 유의하게 감소하였으나 집단 간의 차이는 나타나지 않았다. 이러한 결과는 후방보행의 재활운동이 전방십자인대 재건술을 시행한 환자의 통증을 감소시키고 관절의 가동범위 확보와 고유수용성감각을 회복하는데 긍정적인 효과가 있는 것으로 사료된다.

• The Journal of Korean Physical Therapy
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• 제16권1호
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• pp.157-182
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• 2004

The purpose of this study was to evaluate effects of lumbar stabilizing exercise on the functional recovery and the range of motion of low back pain patients. The subjects were consisted of sixty patients who had non specific chronic low back pain(32 females. 28 males; mean aged 37.3) from 19 to 65 years of age(mean age : 37.3). All subjects randomly assigned to the lumbar stabilizing exercise group, the modalities treatment group, the manual treatment group. Lumbar stabilizing exercise group received manual treatment with lumbar stabilizing exercise for 30minutes, modalities treatment group received hot pack used thermal therapy for 20minutes and ICT used electrical therapy for 20minutes and US or MWD used deep thermal therapy for 15minutes, manual treatment group received modalities treatment with therapeutic massage for 10minutes and joint mobilization or manipulation for 10minutes per day and three times a week during 4 weeks period. The Multilevel Roland-Morris Disability Questionnaire(MR-MDQ) was used to measure functional disability level. Visual Analogue Scale(VAS) was used to measure subjective pain level. Remodified Schober test(RST) was used to measure forward flexion range of motion of lumbar segment. Finger-to-Floor test(F-T-FT) was used to measure forward flexion range of motion of full spine of low back pain patients. All measurements of each patients were measured at pre-treatment and 4 week post-treatment. The results of this study were summarized as follows : 1. The MR-MDQ of lumbar stabilizing exercise group, modalities treatment group, and manual treatment group was significantly reduced between pre-treatment and post-treatment(p<.05). 2. The VAS of lumbar stabilizing exercise group, modalities treatment group, and manual treatment group was significantly reduced between pre-treatment and post-treatment(p<.05). 3. The RST of lumbar stabilizing exercise group, modalities treatment group, and manual treatment group was significantly reduced between pre-treatment and post-treatment(p<.05). 4. The F-T-FT of lumbar stabilizing exercise group, modalities treatment group, and manual treatment group was significantly reduced between pre-treatment and post-treatment(p<.05). 5. The results of analyzed effects of MR-MDQ, RST, F-T-FT were significantly reduced (p<.05), but VAS wasn't significantly reduced(p>.05) between treatment type of lumbar stabilizing exercise group and modalities treatment group and manual treatment group according to pre-treatment and post-treatment. 6. The results of LSD post-hoc to find difference between treatment type of lumbar stabilizing exercise group and modalities treatment group and manual treatment group according to pre-treatment and post-treatment that MR-MDQ was significantly reduced stabilizing exercise group than modalities treatment group(p<.05), and VAS wasn't significantly reduced all treatment group(p>.05), and RST was significantly reduced stabilizing exercise group than modalities treatment group(p<.05), and F-T-FT was significantly reduced stabilizing exercise group than modalities treatment group and manual treatment group (p<.05).

• The Journal of Korean Physical Therapy
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• 제23권1호
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• pp.21-28
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• 2011

Purpose: The aim of this study was to investigate correlations between the Functional Movement Screen (FMS), pain, and performance ability in professional fencing players. Methods: Fifty-six athletes participated in this study. The pain group included those who had a score on a pain-related Visual Analogue Scale (VAS) of ${\geq}$20 and an Oswestry Disability Index (ODI) score ${\geq}$10). In the non-pain group, these scores were: VAS(<20), ODI(<10). The VAS and ODI were used to measure pain throughout the study. Performance ability included motor function of the lower extremities (as assessed by a Modified Functional Index Questionnaire, MFIQ), dynamic balance (Balance system, BS and Posture med, PM), flexor and extensor muscle strength of the lumbar region was recorded as maximal isometric strength. Results: Among athletes who had pain, 5 of 15(33.33%) showed impaired functional movement. Conversely, only 2 of 41(4.88%) of those who had no pain showed such impairment (FMS ${\leq}$14score). The athletes who had pain and who had an FMS score above 14 (10/56; 17.86%) showed a significantly higher score for extensor muscle strength of the lumbar compared with those with pain and an FMS score below 14 (5/56; 8.93%) were significant correlations between the FMS and pain (r=-0.40 to -0.42, p<0.01), the MFIQ (r=-0.33, p<0.05), dynamic balance (r=-0.27 to -0.40, p<0.05-0.01), muscle strength of the lumbar (r=0.27 to 0.29, p<0.05). Stepwise multiple regression analysis showed that the dynamic balance score (${\beta}{\beta}$=-0.41) had slightly more power in predicting FMS score than pain, motor function of lower extremity, or muscle strength. Conclusion: The FMS was significantly associated with values of pain, motor function of the lower extremities, dynamic balance, and muscle strength of the lumbar. However the FMS appears to lack relevance and reasonable evidence to suggest that it is an acceptable measurement tool for functional movement analysis.

• 대한물리의학회지
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• 제3권3호
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• pp.203-213
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• 2008

Purpose : The purpose of the study was to investigate the effects of sustained natural appophyseal glides (SNAGS) on pain and lumbar stability in patients with chronic low back pain. Methods : The subjects were assigned randomly devided SNAGS group(n=18) and control group(n=18). The SNAGS group received Infrared(IR) used thermal therapy for 20minutes, Interference current therapy(ICT) used electrical therapy for 10minutes and SNAGS for 10minutes to 15minutes. The control group received IR used thermal therapy for 20minutes, ICT used electrical therapy for 10minutes and active stretching exercise for 10minutes to 15minutes. The visual analogue scale(VAS) and lumbar stability were measured at pre-treatment and post-treatment. Results : The results of this study were summarized as follows : 1. The VAS score of SNAGS group and control group was significantly within-subjects pre-test and post-test (p<.05), there was significantly difference between-subjects on each groups(p<.05). 2. The SNAGS group was significantly increased in variation of lumbar stability on $0^{\circ}$, $180^{\circ}$, $90^{\circ}$, $-90^{\circ}$, $45^{\circ}$, $-45^{\circ}$, $135^{\circ}$ and $-135^{\circ}$ within-subjects pre-test and post-test(p<.05), but The control group wasn't significantly increased in variation of lumbar stability on $0^{\circ}$, $180^{\circ}$, $90^{\circ}$, $-90^{\circ}$, $45^{\circ}$, $-45^{\circ}$, $135^{\circ}$ and $-135^{\circ}$ within-subjects pre-test and post-test(p>.05). There was significantly difference between-subjects on each groups(p<.05). Conclusion : In conclusion, SNAGS found that effective to decrease of pain and increase of lumbar stability. Therefore, the results of this study suggests that SNAGS is beneficial treatment for chronic low back pain.

• 대한후두음성언어의학회지
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• 제21권2호
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• pp.128-132
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• 2010

Background and Objectives : This study was designed to examine the effect of nasal cavity surgery on voice in terms of nasalance by using subjective test, Visual analogue scale (VAS) and Nasometer and compare the pre op and post op results among patiets with nasal cavity disease. Materials and Method : From April 2009 to November 2009, data of thirty one patients who underwent nasal cavity surgery were prospectively evaluated. 24 males and 7 females with age range between 12 years to 80 years old (average 34 years old) were chosen. VAS was questioned to patients group before, after 1 week, after 1 month, and after 3 months from the surgery. Nasometer, was also conducted. Results: After the surgery symptoms like nasal obstruction, mouth breath, snoring, and sleep apnea were all improved. Improvements for nasal obstruction and mouth breath were observed statistically in post operative day (POD) 1 month and POD 3 months. Also snoring was improved statistically in POD 1 month. Objective nasalance test showed increases in a single and double vowel for POD 3 months. Only /je/ sound statistically-significant increased in all post operative periods. Nasalance increase were observed in other test results. Conclusion : All the symptoms are improved after nasal cavity surgery. Also there are some nasalance changes during whole period of study and return to the pre operative state in POD 3 months. Therefore, patients must be warned and understood about nasalance changes, and surgeons need to aware of various facts, which can affect voice changes before the surgery.