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Prediction of medication-related osteonecrosis of the jaw (MRONJ) using automated machine learning in patients with osteoporosis associated with dental extraction and implantation: a retrospective study

  • Da Woon Kwack;Sung Min Park
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.49 no.3
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    • pp.135-141
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    • 2023
  • Objectives: This study aimed to develop and validate machine learning (ML) models using H2O-AutoML, an automated ML program, for predicting medication-related osteonecrosis of the jaw (MRONJ) in patients with osteoporosis undergoing tooth extraction or implantation. Patients and Methods: We conducted a retrospective chart review of 340 patients who visited Dankook University Dental Hospital between January 2019 and June 2022 who met the following inclusion criteria: female, age ≥55 years, osteoporosis treated with antiresorptive therapy, and recent dental extraction or implantation. We considered medication administration and duration, demographics, and systemic factors (age and medical history). Local factors, such as surgical method, number of operated teeth, and operation area, were also included. Six algorithms were used to generate the MRONJ prediction model. Results: Gradient boosting demonstrated the best diagnostic accuracy, with an area under the receiver operating characteristic curve (AUC) of 0.8283. Validation with the test dataset yielded a stable AUC of 0.7526. Variable importance analysis identified duration of medication as the most important variable, followed by age, number of teeth operated, and operation site. Conclusion: ML models can help predict MRONJ occurrence in patients with osteoporosis undergoing tooth extraction or implantation based on questionnaire data acquired at the first visit.

Measuring Attribute Levels Influencing Tourists' Preference for Restaurants in Tourist Area and Marginal Willingness to Pay: Among Tourists in Jeonnam Area (관광객 선호도에 영향을 미치는 관광지 음식점의 속성수준 평가 및 한계지불의사액 분석: 전남지역 관광객을 대상으로)

  • Kang, Jong-Heon;Jeong, Hang-Jin
    • Journal of the Korean Society of Food Culture
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    • v.22 no.6
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    • pp.794-800
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    • 2007
  • The purpose of this study was to measure the tourists' preference for alternative restaurants with different combinations of 4 attribute levels: origin description, food type, price and service guarantee. A total of 210 questionnaires were completed from tourists who visited Kwangyang, Suncheon and Yeosu during Jan. 2 - Jan. 15, 2007. Conjoint experiment method was used to develop hypothetical restaurants. Ordinal probit model was used to measure the effects of attribute levels on the tourists' preference. Results of the study demonstrated that the ordinal probit model analysis result for the data indicated excellent model fit. The effects of attribute levels (origin description, traditional food, fusion food, price, service guarantee) on the tourists' preference were statistically significant. As expected, estimates of marginal willingness to pay for origin description(3.063), food type(2.349), and service guarantee(2.356) were statistically significant. Moreover, tourists were more willing to pay for origin description than other attribute levels. Tourists also considered the origin description as the very important attribute. In conclusion, based on conjoint analysis, a model was proposed of marginal willingness to pay of attribute levels. It should be noted that the original model was modified and should, preferably, be validated in future research.

Complete Remission of Unresectable Esophageal Cancer Achieved with Concurrent Chemoradiotherapy: A Case Report

  • Jung Min Lee;Bora Keum;Sang Yup Lee;In Kyung Yoo;Seung Han Kim;Hyuk Soon Choi;Eun Sun Kim;Hoon Jai Chun
    • Journal of Digestive Cancer Research
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    • v.5 no.1
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    • pp.70-72
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    • 2017
  • A 41-year old woman with dysphagia visited, which was aggravated after eating. On physical examination, there was a palpable mass on the left supraclavicular area. Endoscopic examination revealed a mass on the distal esophagus with irregular mucosa, erythema and a whitish plaque with luminal narrowing. The patient was diagnosed with unresectable esophageal cancer (squamous cell carcinoma, T3N2M1, Stage IV). The patient received CCRT (total 63 Gy) with cisplatin and 5-fluorouracil (5-FU). After CCRT, the patient took an additionally 2 cycles of chemotherapy for consolidation (cisplatin and 5-FU every 4 weeks). After additional chemotherapy, endoscopic examination showed no residual tumor, a chest CT scan revealed that the mass in the distal esophagus had decreased and there was no enlargement of the lymph nodes around the left supraclavicular area. The patient has been in complete remission for 5 years.

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A Clinical Analysis of Abdominal Stab Injuries (복부 자상 환자에 대한 임상적 고찰)

  • Han, Jae Woong;Kim, Byung Chun;Jung, Jae Pil;Cho, Ji Woong;Chung, Bong Hwa;Chung, Kyung Suk;Kang, Koo Hyun
    • Journal of Trauma and Injury
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    • v.19 no.2
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    • pp.143-149
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    • 2006
  • Purpose: This study was done to evaluate the incidence, type of injury, medical consequences, mortality, and prognostic factors associated with stab wounds in patients who visited Kangnam Sacred Heart Hospital, Hallym University, Seoul, Korea. Methods: A retrospective analysis of the clinical data of 40 patients with abdominal stab wounds who visited Kangnam Sacred Heart Hospital, Hallym University, Seoul, Korea from January 1, 2000 to December 31, 2004. Results: 1) The most prevalent age group was patients in their the twenties to fourties (77.5% of all patients), and average age of the patients was 39.3 years. The male-to-female ratio was 2.07:1. 2) The external site of stab wounds was most commonly the periumbilcal area of the abdomen (14 cases, 33.3%). 3) The most commonly injured organs were the liver and the stomach (10 cases each, 16.9%). 4) Operations were performed on all 40 patients, with 9 (22.5%) negative operation findings. 5) Death occurred in 5 cases (12.5%). 6) The trauma indices of the death group were TRISS 51.9%, RTS 3.6 points, and APACHE II 23.0 points. 7) The average transfusion amount of the death group was 13.8 pints Conclusion: These data suggest that the transfusion amount and the trauma index of abdominal stab injuries may be statistically significant factors for predicting mortality.

Gracilis Muscle Free Flap Transplantation Followed Up Over 10 Years (10년 이상 추시된 박 근 유리 판 이식술)

  • Yu, Chang Eun;Park, Ki Tae;Lee, Jun-Mo
    • Archives of Reconstructive Microsurgery
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    • v.20 no.2
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    • pp.108-112
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    • 2011
  • Purpose: Gracilis muscle free flap transplantation is chosen in the medium sized soft tissue defect and bone exposure from trauma and chronic osteomyelitis in the lower extremity. We set a study to search for gracilis free flaps to know whether symptoms were cured or recurred in patients that have passed over 10 years from flap transplantation. Materials and Methods: From August 1995 through September 2010, we have performed 28 cases of gracilis muscle free flap in the lower extremities. Ever since no case visited to demand any discomfort, breakdown or recurrence in the flap site on outpatient basis. We made a telephone call to patients or relatives documented in the medical record and only 2 cases visited outpatient department and 9 cases postponed the visit who satisfied with the final result but 17 cases had wrong telephone numbers. Causes, area of lower extremity, recipient vessels in the lower extremity, condition of the donor thigh and overall satisfaction of the flap transplantation in activities of daily living were investigated and written down in the medical record. Results: 11 cases were reviewed after average postoperative 13.7 years. Gracilis muscle flaps were not break down at the recipient site in all cases. The wound of donor thigh wound healed good and overall activities of daily living was satisfied in all cases. Conclusion: Gracilis muscle flaps which had performed and followed up average 13.7 years revealed confident in the medium sized soft tissue defect and bone exposure from trauma and chronic osteomyelitis in the lower extremity.

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The Effect of the Selection Attribute of Local Jeonju-bibimhop Restaurants on Customer Satisfaction and Behavioral Intention: Focused on Jeonju area (전주비빔밥 향토음식점의 선택속성이 고객만족과 행동의도에 미치는 영향: 전주지역을 중심으로)

  • Park, Ki-Hong;Lee, Bo-Soon;Kim, Dong-Seok
    • Culinary science and hospitality research
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    • v.17 no.3
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    • pp.47-64
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    • 2011
  • This research try to find the strategic implication through the importance-performance analysis for the customers who visited local Jeonju-Bibimbap restaurants. It also investigates the effect of the selection attribute of the restaurants on customer satisfaction and behavior intention as well as how customer satisfaction affects behavior intention. The survey was conducted targeting those who visited the local restaurants in Jeonju and had Jeonju-Bibimbap, and 251 copies of the questionnaire were used for the final analysis. As a result, the properties 'Environmental cleanliness' and 'Convenience of reservations' in IPA are probed as 'improvement needed as soon as possible'; the 'food(p<0.01)' and 'service(p<0.05)' factors significantly affect customer satisfaction; the 'physical environment(p<0.01)' and 'service(p<0.05)' factors have significant effect on behavior intention; lastly, it has also been found true that customer satisfaction significantly influences behavior intention(p<0.001).

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A Survey of Patients Visiting Pain Clinic (통증 치료실 내원 환자의 분석)

  • Seo, Chang-Min;Mun, Cheol-Won;Baek, Un-Yi;Hong, Jung-Gil
    • The Korean Journal of Pain
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    • v.13 no.2
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    • pp.224-231
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    • 2000
  • Background: Currently, the number of patients visiting pain clinics is increasing with the augmented concerns of the patients about management of pain. We conducted this study in order to comprehend the characteristics of the patients visiting pain clinics and to find a method to further raises the public's awareness about pain treatment. Methods: We surveyed 497 new patients who had visited pain clinic of Kyungpook national university hospital from August 1998 to July 1999. We analysed these patients about their age, sex, chief complaint, duration of pain complaints, resident district, educational level and route of visiting pain clinic by use of questionnaire. Results: In age distribution, the largest proportion (29.8%) were in their 60's. Low back pain was the most common chief complaint (33.0%), the highest (43.7%) percentage of patients had complained of pain for over 6 months. Two thirds of the patients lived in urban area. Patients who were educated to only elementary school level made up the largest group with 35.3%. Referrals from former patients who had visited our pain clinic and had received treatment. Conclusions: As increasing patients who have pain complaints are related to social advanced age, it is prudent to consider the characteristics of age related pain complaints. And we have to guide the pain patients to have more earlier treatments using mass media because there is still insufficient general information about pain clinic and pain managements.

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A Comparative Analysis of Elderly Intoxication Patient between Urban and Rural Area for the Safety Management and Emergency Care (농촌과 도시지역 노인약물중독환자의 응급처치와 약물중독안전관리에 대한 연구)

  • Rhim, Jae-Dong;Cho, Byung-Jun;Seoung, Youl-Hun;Kim, Seon-Rye
    • Journal of the Korea Safety Management & Science
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    • v.12 no.1
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    • pp.19-25
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    • 2010
  • To investigate acute drug intoxication trends in the elderly visited Emergency Medical Centers, Data was collected from the records of poisoning patients visited Five different Hospitals from January 1. 2007 to December 31. 2007. The analysis was conducted by using 135 cases of 624 cases. When considering only the elderly and making comparisons between the urban areas and the rural areas the following data was produced. In regard to patients with acute drug intoxication, the main substance of choice was pesticides. Cases of acute drug intoxication are definitely higher for those categorized as the rural elderly (75.0%) when compared with those categorized as the urban elderly (44.1%). The male to female ratio, those living together as a family, past suicide attempts, mental state and sobriety condition when they came, monthly distribution etc. between the two groups did not demonstrate a difference between them. In regard to reasons given for acute drug intoxication, suicide was the highest at 60.7% of the cases. When comparing accidental reasons for poisoning, the urban elderly, at 34.2% of their cases, were higher than in the rural elderly, at 23.7%. After first aid was administered, the admission rate was higher for the rural elderly (47.4%) than for the urban elderly (33.9%). This shows that the rural elderly have a more severe acute drug intoxication poisoning problem than the urban elderly do.

A Study of Western Food Experience and the Influence of Sauce on Food Quality (서양요리의 이용실태 및 소스(Sauce)가 음식품질에 미치는 영향)

  • 김현덕;이연정;한재숙
    • Journal of the East Asian Society of Dietary Life
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    • v.12 no.4
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    • pp.307-317
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    • 2002
  • The purpose of this study was to research Koreans western food experiences and the influence of sauce on food quality. Among 1,340 respondents, 660 were males and 680 femails in Daegu and Kyeongbuk area. The first part of this study was about their experiences on western foods. As the main motivation to visit western restaurants, 33.2% responded the facilities and atmosphere and 23.7% because they liked western foods. Family was the most common group of company with 33.5% of respondents when they visited the restaurants. In terms of monthly frequency, most of them (60.7%) visited 1~2 times a month. Taste of food was the main factor (34.0%) for choosing western foods. But taste of food was also the most common dissatisfaction with western foods for 36.2% of respondents. Price of foods was next (31.6%) and quality of waiter and waitress services was the third most common factor (13.6%). The second part of the study was an investigation of the influence of sauce on food quality. 35.0% of respondents tasted the sauce at the hotel restaurant. 40.5% of respondents indicated sauce influenced the image of the western foods and 40.9% indicated the level of the influence as substantial. In total, 81.4% of respondents answered that the quality of the quality of the sauce influenced the image of the western foods. In general, the influence of sauce on western food quality was perceived as a significant contributing factor with an average 4.00 on 5-point scale in 15 questionaires. Notably, the questionnaire, "The taste of the western food is improved mostly with sauce." ranked the highest with 4.45 on the 5-point scale.int scale.

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Actual Condition and Utilization of the Youth Culture Center as the Residential Infrastructure - Focused on the Youth Culture Center in Daejeon Metropolitan City - (주거지 인프라로서의 청소년문화의집 현황 및 이용실태 - 대전광역시 청소년문화의집을 중심으로 -)

  • Park, Jung-a
    • Journal of the Korean housing association
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    • v.27 no.5
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    • pp.55-63
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    • 2016
  • This study intended to establish a direction for the revitalization of youth culture centers by examining the current status of youth centers operated in Daejeon and how they have been used. Four youth centers in Daejeon were visited and a survey was conducted targeting 180 people using the centers. Frequency, Mean, and ${\chi}^2$ analysis were performed by using SPSS statistics package, and major research outcomes are as follows; There were 6 youth culture centers in Daejeon and showed a lower construction rate of 7.4% on the basis of 81 up, myun and dong. Most youth centers were small, around $300-500m^2$ in total floor area, and accommodated 100-200 people, and the space comprised multipurpose hall, cafeteria, open space, club space, multimedia space, information service room, and guide booth. There were no sports spaces among the target facilities. So, it has created the need for physical activity space to promote health & development. Most users visited centers with their friends and simply to use the facilities, and the satisfaction with the facilities was relatively high at 4.32. The role of the local community and financial support of the government is required to activate the youth culture. Also, for the role of youth culture center, it was suggested that the youth culture center should develop program which corresponds with the level of the youth and boast the interest of the youth.