• Proceedings of the Korea Contents Association Conference
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• 2016.05a
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• pp.433-434
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• 2016

Cerebellar atrophy was found that a patient was taking oral phenytoin for 3 years. 53 years old female patient with General tonic clonic(GTC) type seizure was prescribed phenytoin. In the process, she developed ataxic gate, dysarthria. Brain magnetic resonance imaging(MRI) finding was revealed differential diagnosis cerebellar atrophy. She was prescribed epileptol instead of phenytoin. But leukopenia, thrombocytopenia occurred. As a result, phenytoin restarted. Development of medical state decreased abuse of anticonvulsants. Considering various convulsive disorders, we must give attention to using anticonvulsants.

• Development and Reproduction
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• v.13 no.2
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• pp.63-77
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• 2009

The neuronal ceroid-lipofuscinoses (NCLs) are a kind of neurodegenerative storage disorders. The NCLs are charecterizated by accumulation of autofluorescent lipofuscin or lipopigment in the brain. All NCL group belongs to in lysosomal storage disorders (LSDs), except Northern epilepsy. NCLs are the most common group of progressive neurodegenerative disorders in childhood, with an incidence as high as I in 12,500 live births. Four main clinical types have been described based on the onset age : infantile, late infantile, juvenile and adult types. Clinical symptoms of NCLs include loss of vision, seizures, epilepsy, progressive mental retardation and a premature death. Although mutation causes neurodegeneration in NCLs, the molecular mechanism by which mutation leads to neurodegeneration remains unclear. In this paper, we review the characteristics of these NCLs.

• The Journal of the Korea institute of electronic communication sciences
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• v.16 no.1
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• pp.117-124
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• 2021

Among growth disorders, 'Short Stature' can be improved through rapid diagnosis and treatment, and for that, it is important to detect early'Short Stature'. It is recommended to measure the height steadily for early detection of 'Short Stature' and checking the kid's growth process, but existing height measurement methods have problems such as time and space limitations, cost occurrence, and difficulty in keeping records. So in this paper, we proposed an 'Development of Kid Height Measurement Application based on Image using computer vision' method using smart phones, a medium that is highly accessible to people. In images taken through a smartphone camera, the kid's height is measured using algorithms from OpenCV, a computer vision library, and the measured heights were printed on the screen through 'a comparison graph with the standard height by gender and age' and 'list by date', made possible to check the kid's growth process. It is expected to measure height anytime, anywhere without time and space limitations and costs through this proposed method, and it is expected to help early detection of 'Short Stature' and other disorder through steady height measurement and confirmation of growth process.

• The Journal of Korean Society for School & Community Health Education
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• v.22 no.1
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• pp.11-24
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• 2021

Objectives: The purpose of this study was to examine the Path modeling effect among depression, Post-Traumatic Stress Disorders (PTSD), resilience, and social support on the quality of life (QoL) of natural disaster victims. Methods: This is a cross-sectional study with 1,979 disaster victims' cases by using the 4th Disaster victims panel survey in Korea. Data were collected from october 2018 to december 2018 and analyzed using regression analysis and path way analysis. Results: Perceived health, depression, social support, PTSD, resilience, and QoL showed significant correlations. PTSD was directly affected by depression and QoL was affected by PTSD. Social support was directly affected by depression and resilience was also directly affected by depression. QoL was affected by social support and resilience. Conclusion: This analysis highlighted that the relation between lower depression and QoL was mediated by greater social support and resilience and lower degree of PTSD. These results suggest that community health interventions and education that incorporate social support and resilience may improve the quality of life of natural disaster victims.

• Proceedings of the Korea Information Processing Society Conference
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• 2022.11a
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• pp.541-543
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• 2022

In recent years, retinal disorders have become a serious health concern. Retinal disorders develop slowly and without obvious signs. To avoid vision deterioration, early detection and treatment are critical. Optical coherence tomography (OCT) is a non-invasive and non-contact medical imaging technique used to acquire informative and high-resolution image of retinal area and underlying layers. Disease signs are difficult to detect because OCT images have many areas which are not related to any disease. In this paper, we present a deep learning-based method to perform multi-label classification on a long-tailed OCT dataset. Our method first extracts the region of interest and then performs the classification task. We achieve 98% accuracy, 92% sensitivity, and 99% specificity on our private OCT dataset. Using the heatmap generated from trained convolutional neural network, our method is more robust and explainable than previous approaches because it focuses on areas that contain disease signs.

• Journal of Korean Public Health Nursing
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• v.33 no.2
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• pp.242-257
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• 2019

Purpose: This study examined the life experiences of the wives of men who were born with normal vision but gradually developed a visual impairment, with particular focus on their way of facing and coping with their life crisis. Method: A narrative approach was used to not only understand women's experiences within sociocultural contexts, but also reveal the subjective meaning of their personal life stories through their own voices. A purposive sample of three participants having husbands unexpectedly diagnosed with visual impairment during their marriage was recruited. The data were analyzed using the narrative analysis methods suggested by Clandinin and Connelly. Results: The wives took the crisis of their husbands' visual impairment as an economic crisis of the family. They faced a variety of difficulties, including extreme despair, role changes, and economic burdens. On the other hand, they tried to keep the family secure through a range of coping strategies that were motivated by compassion toward the husbands, maternal affection for the children, and a sense of responsibility for their families. Conclusion: This study revealed the need for financial support for temporarily disadvantaged families. In addition, various nursing and counseling programs for the family members will also be needed to help recover the family functions.

• Journal of Korean Ophthalmic Optics Society
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• v.9 no.1
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• pp.105-115
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• 2004

In developed and industrialized countries life expectancy has increased significantly over the past century. As a consequence, the proportion of elderly individuals in these countries has also enlarged with the resulting increased burden on health care providers. In many developing countries the problem of age related and other eye disorders has far outstripped the ability to manage them. Accordingly, the World Health Organization (WHO) has introduced an initiative: Vision 2020 - The Right to Sight, with the objective of eliminating preventable blindness by the year 2020. This paper reviews the broad range of conditions involving external and internal structures of the eye and also the effects of aging on visual functions. It is hoped that this will provide a stimulus for increased study of these disorders, improved clinical diagnosis, and an enhanced interest and role in contributing to the objectives of the WHO and the World Council of Optometry with respect to early diagnosis, prevention and management of the diseases and disorders of the eye that are more prevalent in old age.

• Journal of Korean Ophthalmic Optics Society
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• v.8 no.2
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• pp.135-151
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• 2003

This study compared the effect of Polaroid$^{(R)}$ lenses on binocular vision by assessing visual acuity, stereopsis, and visual evoked potential(VEP), through Polaroid$^{(R)}$, CR 39 and sunglass lenses. The spectral absorptions of Polaroid$^{(R)}$, CR 39 and sunglass lenses were measured using a spectrophotometer (Hitachi. U-3501). The VEP were recorded by the Nicolet system. Thirty normal adult(fifteen males, fifteen females, mean=21.9 years, range=20 to 25) subjects were recorded. The subjects were provided a history including : general health, family health, medication, genetics, allergy and disease. All had normal or corrected to normal acuity with no history of visual disorders. Corrected visual acuity, colour vision and stereopsis were recorded for each subject monocularly and binocularly. Each test was repealed through the sunglass, CR 39, and Polaroid$^{(R)}$ lenses. Subjects viewed the VEP stimulus both monocularly and binocularly through the test lenses while the VEPs were recorded. The results suggest that the binocular visual acuity and stereoacuity is better than with monocular vision. On other hand, the analysis of VEP suggests that the amplitude of wave is smaller when the monocular eye receives the VEP stimulus compared with that when the binocular eye is stimulated by the VEP target with the sunglass, CR 39, and Polaroid$^{(R)}$ lens. But, the latency period of each eye was similar to results between the dominant eye and the non-dominant eye by the CR 39, sunglass, and polaroid lens. In conclusion, this study indicates that the binocular vision appears to be better through the brown Polaroid$^{(R)}$ lens than through the other test lenses.

• Korean Journal of Acupuncture
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• v.21 no.2
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• pp.69-79
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• 2004

Objective : Acupuncture has been used for treatment of numerous disorders, especially for pain control in Oriental Medicine. However, the mechanism of pain control by acupuncture was not clear until now. This study was performed to prove analgesic mechanism of acupuncture treatment at acupoint $ST_{36}$ by observing the changes of abdominal pain and c-Fos expression in the thalamus. Methods : Abdominal pain was induced by acetic acid, and the changes of writhing reflex after acupuncture treatment on $ST_{36}$ and non-acupoints were measured. c-Fos immunohistochemistry was also performed to study the changes of the neuronal activity in the thalamus. Results : The writhing reflex decrease significantly after acupuncturing at $ST_{36}$ compared with control group(p<0.05). The changes of the writhing reflex by non-acupoint acupuncture treatment also showed significant decrease compared with control group(p<0.05). c-Fos expression in the thalamus, especially periventricular part was significantly decreased after acupuncturing as $ST_{36}$ compared with control groups(p<0.05). Conclusion : This study shows that the acupuncture has the analgesic effect in the abdominal pain induced by acetic acid and the thalamus might be a important area for this mechanism.

• Journal of Genetic Medicine
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• v.10 no.1
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• pp.13-19
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• 2013

Retinitis pigmentosa (RP) is the most common hereditary retinal disorder and is characterized by progressive retinal degeneration and decline in vision. RP comprises a heterogeneous group of disorders caused by various genetic variants. Since the first discovery of the causal mutation in the RHO gene using positional cloning, numerous mutations have been detected in more than 60 loci and 50 genes. However, causal genes have not been discovered in about 50% of cases. We attempt here to review the strategies to identify causal alleles of retinitis pigmentosa. These include conventional methods as well as state-of-the-art technologies based on next-generation sequencing.