• Title/Summary/Keyword: viscous blood

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APPLICATION OF DOUBLE DECOMPOSITION TO PULSATILE FLOW

  • Mamaloukas, C.;Haldar, K.;Mazumdar, H.P.
    • Journal of applied mathematics & informatics
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    • 제10권1_2호
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    • pp.193-207
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    • 2002
  • The present investigation deals with the pulsatile flow of incompressible viscous fluid through a circular rigid tube provided with constriction. The method applied here is the Decomposition Method, which has been developed by George Adomian [3]. The advantages of this method are the avoidance of simplifications and restrictions, which change the non-linear problem to mathematically tractable one, whose solution is not consistent with physical solution. Theoretically results, such as, wall shear stress and axial velocity component, have been obtained and the graphical solutions of these theoretical results have been shown in the figures.

점탄성 유체의 난류 해석을 위한 수정된 $k-{\varepsilon}$ 난류모델 개발 및 혈류역학에의 적용 (DEVELOPMIN OF A MODIFIED $k-{\varepsilon}$ TURBULENCE MODEL FOR VISCO-ELASTIC FLUID AND ITS APPLICATION TO HEMODYNAMICS)

  • 노경철;유홍선
    • 한국전산유체공학회:학술대회논문집
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    • 한국전산유체공학회 2010년 춘계학술대회논문집
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    • pp.214-220
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    • 2010
  • This article described that a high Reynolds number version of a turbulence model was modified by using drag reduction to analyze the turbulent flows of non-Newtonian fluid with visco-elastic viscosity and it was applied hemodynamics which was representative of visco-elastic fluid. The turbulence characteristics of visco-elastic fluid was expanded viscous sublayer region and buffer layer region by drag reduction phenomenon and also Newtonian turbulence models does not predict because viscosity was related with shear rate of fluid flow. Hence numerical simulation using a modified turbulence model was conducted under the same conditions that were applied to obtain the experiment results and previous turbulence models and then the numerical investigation of turbulent blood flow in the stenosed artery bifurcation under periodic acceleration of the human body.

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수정멱법칙 비뉴턴유체의 협착관내 유동장해석 (Flow Analysis of the Modified Power-Law Non-Newtonian Fluids in the Stenotic Tubes)

  • 서상호;유상신;장남일
    • 설비공학논문집
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    • 제6권3호
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    • pp.227-236
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    • 1994
  • Steady flows of Newtonian and non-Newtonian fluids in the stenotic tubes with various stenotic shapes are numerically simulated. Validity of the modified power-law model as a constitutive equation for the purely viscous non-Newtonian fluid is discussed and the results of the power-law model are compared with those of the Carreau model, the Powell-Eyring model and experimental data for blood. Flow characteristics and reattachment lengths for non-Newtonian fluids in the stenotic tubes are presented extensively. Also, the analysis is extended to predict the influences of diameter ratio, stenosis spacing, number of stenosis and Reynolds number on the flow characteristics in the multiple stenotic tubes.

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선복화 에탄올 추출물의 급성 독성 연구 (Safety Evaluation of Ethanol Extract of Inulae Flos : Single-dose Oral Toxicity Study in Mice)

  • 권다혜;김민영;황보현;지선영;박철;최영현;홍수현
    • 대한한의학방제학회지
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    • 제28권2호
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    • pp.169-177
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    • 2020
  • Objectives : This experiment was designed to assess the single oral toxicity of Ethanol Extract Inulae Flos (IF) ethanol extracts. IF is one of the important herbs to remove phlegmy which is the viscous turbid pathological product that can accumulate in the body, causing a variety of diseases. Nevertheless, there has been a lack of research on the pharmacology toxicity of IF. Methods : In this study, IF was orally administered to 5 weeks ICR mice as an oral dose of 2,000 or 3,000 or 5,000 mg/kg. The condition of the mice was observed for 14 days and their weights were measured every two days. Results : None of the mice died for 14 days. The abnormal clinical symptoms and anatomical signs of toxicity were not found in any treatment groups. The gain of net body weight was observed. There was also no significant difference in the organ weight. The serum biochemistry and hematological analysis showed a decrease in BUN, red blood cells, white blood cells and platelets although within the normal ranges. Conclusions : These results suggest that the 50% lethal dose of IF is more than 5,000 mg/kg. This could be thought that IF is a safe drug without acute toxicity and side effects. However, IF showed some weight loss and change in blood test, so it will need to be careful when using it for high doses.

Immediate Post-laparotomy Hypotension in Patients with Severe Traumatic Hemoperitoneum

  • Lee, Gil Jae;Lee, Min A;Yoo, Byungchul;Park, Youngeun;Jang, Myung Jin;Choi, Kang Kook
    • Journal of Trauma and Injury
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    • 제33권1호
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    • pp.38-42
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    • 2020
  • Purpose: Immediate post-laparotomy hypotension (PLH) is a precipitous drop in blood pressure caused by a sudden release of abdominal tamponade after laparotomy in cases of severe hemoperitoneum. The effect of laparotomy on blood pressure in patients with significant hemoperitoneum is unknown. Methods: In total, 163 patients underwent laparotomy for trauma from January 1, 2013 to December 31, 2015. Exclusion criteria included the following: negative laparotomy, only a hollow viscous injury, and hemoperitoneum <1,000 mL. After applying those criteria, 62 patients were enrolled in this retrospective review. PLH was defined as a decrease in the mean arterial pressure (MAP) ≥10 mmHg within 10 minutes after laparotomy. Results: The mean estimated hemoperitoneum was 3,516 mL. The incidence of PLH was 23% (14 of 62 patients). The MAP did not show significant differences before and after laparotomy (5 minutes post-laparotomy, 67.5±16.5 vs. 68.3±18.8 mmHg; p=0.7; 10 minutes post-laparotomy, 67.5±16.5 vs. 70.4±18.8 mmHg; p=0.193). The overall in-hospital mortality was 24% (15 of 62 patients). Mortality was not significantly higher in the PLH group (two of 14 [14.3%] vs. 13 of 48 [27.1%]; p=0.33). No statistically significant between-group differences were observed in the intensive care unit and hospital stay. Conclusions: PLH may be less frequent and less devastating than it is often considered. Surgical hemostasis during laparotomy is important. Laparotomy with adequate resuscitation may explain the equivalent outcomes in the two groups.

MANAGEMENT OF HASĀH WA RAML AL-KULYA (NEPHROLITHIASIS) IN UNANI SYSTEM OF MEDICINE: A REVIEW

  • Khan, Khalid Ali;Khan, Rashid Ali;Zakir, Mohammad
    • 셀메드
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    • 제10권3호
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    • pp.19.1-19.6
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    • 2020
  • The kidneys are exposed to toxicants and waste product and can be affected easily by these toxicants and by products of the metabolism. The consumption of adequate water is necessary to remove waste and to keep kidney healthy. Deficiency of liquid in the blood leads to various adverse effects on the kidney. The most common adverse deficiency of liquid in blood is deposition of solid matter in the kidney and subsequently formation of kidney stone. Nephrolithiasis (kidney stone) can be treated by drugs if it is small in size but if it blocks the route due to its big size then surgery is the only way to remove it. The recurrence rate of the problem is very high and it may reappear within 10 years. In Unani literature Hasāh wa Raml al-Kulya (nephrolithiasis) is described in detail. As per Unani literature stagnation of Ghalīz mādda (filthy and viscous matter) in the kidney is the main cause of the formation of kidney stone. Various single and compound formulations drugs are described for the management of kidney stone which are very effective as well as safe. Management is divided into two parts i.e. symptomatic treatment to relieve pain and to methods adopted to remove stone from the kidney. Musakkin-i-Waja'(analgesic) drugs are used for pain while Mufattit-i-Hasāh (lithotriptic) and Mudirr-i-Bawl (Diuretic) drugs are used to remove stone. Majoon Aqrab, Qurs Kaknaj and Dawa-e-Gurda etc. are compound drugs mentioned in literature for removal of kidney stone. Single drugs like Alu Balu, Tukhm Khayar, and Kharkhask etc. are also used for same purpose.

기구(氣口), 인영맥(人迎脈)의 진단(診斷)을 통(通)한 내상(內傷), 외감병기(外感病機)에 대(對)한 문헌적(文獻的) 고찰(考察) (Invastigating literatures about mechanism of internal·external damage, through Qi mouth and Renying)

  • 김무신;조명래;박영배
    • Journal of Acupuncture Research
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    • 제18권4호
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    • pp.161-177
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    • 2001
  • Objective : We have studied the part, definition, diagnostic generaliztion and pathological viewpoint of Qi mouth and Renying by refering literatures Methods : I refered to records from anciant to modern. The results are followings : 1. Qi mouth and Renying is ancient diagnostic method and the origin of diagnostic method through the pulsation of radial artery. And Qi mouth is recognized as the right and left Qi mouth and Renying is located on pulsation points of both common carotid arteries. 2. The yin of five viscera, nutritional blood and viscous liquid are diagnosed by Qi mouth which is inclued lung meridian. And the yang of six organs, guarding Qi and the rise and fall of stomach energy are diagnosed by Renying which is inclued stomach meridian. 3. It is possible that the position, process and transformational condition of disease are decided by comparing and examining Qi mouth and Renying.

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Chongkukjang Mucilage Stimulates Immunohistochemical Activities of Gastrointestinal Tract in Rats

  • Lee, Chang-Hyun;Yang, Eun-In;Song, Geun-Seoup;Chai, Ok-Hee;Kim, Young-Soo
    • Food Science and Biotechnology
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    • 제14권6호
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    • pp.813-817
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    • 2005
  • We investigated the effect of a viscous substance from chongkukjang (chongkukjang mucilage) on immunohistochemical reactions in rat gastrointestinal (GI) tracts, Rats fed a steady diet of chongkukjang mucilage showed an increase in the immunoreactive densities of gastrin and serotonin in the pyloric region of their stomachs and duodenal villi, The number of gastrin and serotonin immunoreactive cells was significantly higher in the experimental group than in the control group. Feeding on dietary chongkukjang mucilage increased the immunohistochemical densities of $CD4^+$ and $CD8^+$ lymphocytes in the mucosa and submucosa of the rats' gastroduodenal region. The universal nitric oxide synthase (uNOS)-immunoreactive neurons and nerve fibers were strongly stained in the vascular walls of the submucosa and myenteric plexus in rats fed the test diet. The results indicate that the intake of chongkukjang mucilage could increase mucosal immune activity, gastrointestinal motility, and blood circulation in the GI tract.