• Structural Engineering and Mechanics
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• 제90권1호
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• pp.83-96
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• 2024

This paper suggests an analytical approach to investigate the free vibration and stability of functionally graded (FG) beams with both perfect and imperfect characteristics using a quasi-3D higher-order shear deformation theory (HSDT) with stretching effect. The study specifically focuses on FG beams resting on variable elastic foundations. In contrast to other shear deformation theories, this particular theory employs only four unknown functions instead of five. Moreover, this theory satisfies the boundary conditions of zero tension on the beam surfaces and facilitates hyperbolic distributions of transverse shear stresses without the necessity of shear correction factors. The elastic medium in consideration assumes the presence of two parameters, specifically Winkler-Pasternak foundations. The Winkler parameter exhibits variable variations in the longitudinal direction, including linear, parabolic, sinusoidal, cosine, exponential, and uniform, while the Pasternak parameter remains constant. The effective material characteristics of the functionally graded (FG) beam are assumed to follow a straightforward power-law distribution along the thickness direction. Additionally, the investigation of porosity includes the consideration of four different types of porosity distribution patterns, allowing for a comprehensive examination of its influence on the behavior of the beam. Using the virtual work principle, equations of motion are derived and solved analytically using Navier's method for simply supported FG beams. The accuracy is verified through comparisons with literature results. Parametric studies explore the impact of different parameters on free vibration and buckling behavior, demonstrating the theory's correctness and simplicity.

• Clinical and Experimental Pediatrics
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• 제59권sup1호
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• pp.49-52
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• 2016

X-linked agammaglobulinemia (XLA) is a hereditary humoral immunodeficiency that results from Bruton's tyrosine kinase (BTK ) gene mutations. These mutations cause defects in B-cell development, resulting in the virtual absence of these lymphocytes from the peripheral circulation. Consequently, this absence leads to a profound deficiency of lg all isotypes, and an increased susceptibility to encapsulated bacterial infections. A 15-month-old Korean boy presented with recurrent sinusitis and otitis media after 6 months of age, and had a family history of 2 maternal uncles with XLA. Laboratory tests revealed a profound deficiency of Ig isotypes, and a decreased count of $CD19^+$ B cells in the peripheral circulation. Based on his family history and our laboratory test results, he was diagnosed with XLA. We performed BTK gene analysis of peripheral blood samples obtained from family members to confirm the diagnosis. Mutational analysis revealed a novel hemizygous frameshift mutation (c.82delC, p.Arg28Alafs*5), in the BTK gene. His mother and maternal grandmother were heterozygous carriers of this mutation and his two maternal uncles were hemizygous at the same position. After XLA diagnosis, intravenous immunoglobulin (400 mg/kg, monthly) treatment was initiated; recurrent sinusitis and otitis media were subsequently brought under control. To our knowledge, this is the first reported case of a Korean pedigree with a novel mutation in the BTK gene.

• Applied Microscopy
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• 제36권1호
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• pp.7-16
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• 2006

가속전압 1.3MV의 초고전압투과전자현미경의 원격제어 시스템을 개발하였다. 초고전압투과전자현미경의 운영을 위한 필수적인 기능, 즉 stage조정, 시편의 tilting, TV카메라 선택과 영상 저장 등을 원격 운영시스템에 그대로 적용하였다. 특히 이 시스템은 간단한 웹 접속만으로 goniometer를 완벽하고 정밀하게 제어할 수 있으며 고해상도 디지털카메라를 제어할 수 있는 특징을 가지고 있다. 일체의 현미경 제어 신호 및 교신은 글로리아드 망을 통하여 이루어지도록 하였다. 이는 HVEM원격 운영시스템을 이용하여 국내는 물론 국제적인 공동 연구를 수행할 수 있는 가상 실험실 구축을 실현할 수 있음을 시사한다.

• International Journal of Control, Automation, and Systems
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• 제1권3호
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• pp.301-307
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• 2003

A control system design based on coupled nonlinear oscillators (CNOs) for a self- organized swarm system is presented. In this scheme, agents self-organize to flock and arrange group formations through attractive and repulsive forces among themselves using CNOs. Virtual agents are also used to create richer group formation patterns. The objective of the swarm control in this paper is to follow a moving target with a final group formation in the shortest possible time despite some obstacles. The simulation results have shown that the proposed scheme can effectively construct a self-organized multi-agent swarm system capable of group formation and group immigration despite the emergence of obstacles.

• ETRI Journal
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• 제27권5호
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• pp.635-638
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• 2005

Spatial audio coding (SAC) is an extremely high compact representation of encoded multi-channel audio material. This paper suggests a multi-channel audio service in the terrestrial digital multimedia broadcasting (T-DMB) system using a novel SAC tool, which is called a virtual source location information (VSLI)-based SAC tool. Intensive experiments are presented to evaluate the validity of the proposed VSLI-based SAC tool, and prototypical systems are also presented to demonstrate the reliability of the proposed multi-channel T-DMB system in real applications.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2011년도 춘계학술대회 논문집
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• pp.1043-1048
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• 2011

In the case of a low density branch line, these areas are operating at a loss. So much money is used for infrastructure maintenance cost. To solve the problem, our institute have a project to develop the Information & Communication Technology based train operation system. In a similar research in the Europe, The UK's Transport Research Laboratory experienced analysis of operational issue for developing ERTMS from Level II to Level III. In this paper, we study about railway operational issues before development of ICT based train operation system. An analysis target of operational issues are railway business process & data, drivability and moving or virtual block system.

• The Journal of the Acoustical Society of Korea
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• 제21권4E호
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• pp.170-177
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• 2002

The goal of the present research is to improve a quality of life of the elderly with a dementia. In this paper, it is realized by developing the dialog system that is controlled by three kinds of modules such as speech recognition engine, graphical agent, or database classified by a nursing schedule. The system was evaluated in an actual environment of a nursing facility by introducing it to an older male patient with dementia. The comparison study between dialog system and professional caregivers was then carried out at nursing home for 5 days in each case. The evaluation results showed that the dialog system was more responsive in catering to needs of dementia patient than professional caregivers. Moreover, the proposed system led the patient to talk more than caregivers did.

• ETRI Journal
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• 제21권4호
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• pp.9-22
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• 1999

This paper considers a problem of configuring both physical backbone and logical virtual path (VP) networks in a reconfigurable asynchronous transfer mode (ATM) network where links are subject to failures. The objective is to determine jointly the VP assignment, the capacity assignment of physical links and the bandwidth allocation of VPs, and the routing assignment of traffic demand at least cost. The network cost includes backbone link capacity expansion cost and penalty cost for not satisfying the maximum throughput of the traffic due to link failures or insufficient link capacities. The problem is formulated as a zero-one non-linear mixed integer programming problem, for which an effective solution procedure is developed by using a Lagrangean relaxation technique for finding a lower bound and a heuristic method exploited for improving the upper bound of any intermediate solution. The solution procedure is tested for its effectiveness with various numerical examples.

• Interaction and multiscale mechanics
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• 제2권3호
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• pp.235-261
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• 2009

This study illustrates the differences between the elasto-plastic cap model and Lade's model with Cosserat rotation through the analyses of two large-scale geosynthetic-reinforced soil (GRS) retaining wall tests that were brought to failure using a monotonically increasing surcharge pressure. The finite element analyses with Lade's model were able to reasonably simulate the large-scale plane strain laboratory tests. On average, the finite element analyses gave reasonably good agreement with the experimental results in terms of global performances and shear band occurrences. In contrast, the cap model was not able to simulate the development of shear banding in the tests. In both test simulations the cap model predicted failure loads that were substantially less than the measured ones.

• Computers and Concrete
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• 제22권1호
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• pp.83-91
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• 2018

Various systems for simulating particulate matter are developed and used in concrete technology for producing virtual cementitious materials on the different levels of the microstructure. Basically, the systems can be classified as two distinct families, namely random sequential addition systems (RSAs) and discrete element methods (DEMs). The first type is hardly being used for this purpose outside concrete technology, but became popular among concrete technologists. Hence, it is of utmost relevance to compare the two families in their capabilities, so that the reliability of produced data can be estimated. This paper pursues to do this on the basis of earlier published material of work performed by a succession of PhD students in the group of the second author. Limited references will be given to external sources.