• Proceedings of the Korean Radioactive Waste Society Conference
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• 한국방사성폐기물학회 2003년도 가을 학술논문집
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• pp.388-394
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• 2003

To handle the high level radioactive materials such a spent fuel, the master-slave manipulators (MSM) are widely used as a remote handling device in nuclear facilities such as the hot cell with sealed and shielded space. In this paper, the Digital Mockup which simulates the remote operation of the Advanced Conditioning Process(ACP) is developed. Also, the workspace and the motion of the slave manipulator, as well as, the remote operation task should be analyzed. The process equipment of ACP and Maintenance/Handling Device are drawn in 3D CAD models using IGRIP. Modeling device of manipulator is assigned with various mobile attributes such as a relative position, kinematics constraints, and a range of mobility, The 3D graphic simulator using the external input device of space ball displays the movement of manipulator. To connect the external input device to the graphic simulator, the interface program of external input device with 6 DOF is deigned using the Low Level Tele-operation Interface(LLTI). The experimental result shows that the developed simulation system gives much-improved human interface characteristics and shows satisfactory response characteristics in terms of synchronization speed. This should be useful for the development of work's education system in the virtual environment.

• Journal of Communications and Networks
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• 제15권3호
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• pp.312-320
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• 2013

Home evolved Node-B (HeNB), also called a femtocell or a femto base station, is introduced to provide high data rate to indoor users. However, two main problems arise in femtocell networks: (1) Small coverage area of HeNB, which results in limited cell-splitting gain and ping-pong handover (HO) problems and (2) high inter-femtocell interference because HeNBs may be densely deployed in a small region. In this study, an efficient cooperation mechanism called an HeNB-aided virtual-HO (HaVHO) scheme is proposed to expand the coverage area of femtocells and to reduce inter-femtocell interference. The cooperation among neighbor HeNBs is exploited in HaVHO by enabling an HeNB to relay the data of its neighbor HeNB without an HO. The HaVHO procedure is compatible with the existing long term evolution specification, and the information exchange overhead in HaVHO is relatively low. To estimate the signal to interference plus noise ratio improvement, the area average channel state metric is proposed, and the amount of user throughput enhancement by HaVHO is derived. System-level simulation shows that HaVHO has a better performance than the other four schemes, such as lesser radio link failure, lesser ping-pong handover, lesser short-stay handover, and higher user throughput.

• Journal of Hydrogen and New Energy
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• 제31권6호
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• pp.605-613
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• 2020

In July and October of this year, the government announced the 'Green new deal plan within the Korean new deal policy' and 'Strategies for proliferation of future vehicles and market preoccupation'. And, in response to changes in the global climate agreement, it has decided to expand green mobility such as electric vehicles and hydrogen electric vehicles with the aim of a "net-zero" society. Accordingly, the goal is to build 310 hydrogen refueling stations along with the supply of 60,000 hydrogen vehicles in 2022, and the hydrogen infrastructure is being expanded. however, it is difficult to secure hydrogen infrastructure due to expensive construction costs and difficulty the selection of a site. In Korea, it is possible to build a mobile hydrogen station according to the safety standards covering special case of the Ministry of Industry. Since the mobile hydrogen station can be charged while moving between authorized place, it has the advantage of being able to meet a large number of demands with only one hydrogen refueling station, so it is proposed as a model suitable for the early market of hydrogen infrastructure. This study demonstrates the establishment of a hydrogen refueling station by deriving a virtual accident scenario for leakage and catastrupture for each facility for the risk factors in a mobile hydrogen station, and performing a quantitative risk assessment through the derived scenario. Through the virtual accident scenario, direction of demonstration and implications for the construction of a mobile hydrogen refueling station were derived.

• Biomolecules & Therapeutics
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• 제30권5호
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• pp.427-434
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• 2022

The drug repurposing strategy has been applied to the development of emergency COVID-19 therapeutic medicines. Current drug repurposing approaches have been directed against RNA polymerases and viral proteases. Recently, we found that the inhibition of the interaction between the SARS-CoV-2 structural nucleocapsid (N) and spike (S) proteins decreased viral replication. In this study, drug repurposing candidates were screened by in silico molecular docking simulation with the SARS-CoV-2 structural N protein. In the ChEMBL database, 1994 FDA-approved drugs were selected for the in silico virtual screening against the N terminal domain (NTD) of the SARS-CoV-2 N protein. The tyrosine 109 residue in the NTD of the N protein was used as the center of the ligand binding grid for the docking simulation. In plaque forming assays performed with SARS-CoV-2 infected Vero E6 cells, atovaquone, abiraterone acetate, and digoxin exhibited a tendency to reduce the size of the viral plagues without affecting the plaque numbers. Abiraterone acetate significantly decreased the accumulation of viral particles in the cell culture supernatants in a concentration-dependent manner. In addition, abiraterone acetate significantly decreased the production of N protein and S protein in the SARS-CoV-2-infected Vero E6 cells. In conclusion, abiraterone acetate has therapeutic potential to inhibit the viral replication of SARS-CoV-2.

• Journal of KIISE:Databases
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• 제34권2호
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• pp.166-178
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• 2007

The ALE specification of EPCglobal is leading the development of RFID standards, includes the Event Cycle Specification (ECSpec) describing how long a cycle is, how to filter RFID tag data and which reader is interested in. The ECSpec is a specification for filtering and collecting RFID tag data. It is registered to a middleware for long time and is evaluated to return results satisfying the requirements included in it. Thus, it is quite similar to the continuous query. It can be transformed into a continuous query as its predicate in WHERE clause is characterized by the long interval. Long intervals cause problems deteriorating insertion and search performance of existing query indices. In this paper, we propose a TLC-index as a new query index structure for long interval data. The TLC-index has hybrid structure that uses the cell construct of CQI-index with the virtual construct of VCR-index for partitioning long intervals. The TLC-index can reduce the storage cost and improve the insertion performance through decomposing long intervals into one or more cell constructs that have long size. It can also improve the search performance through decomposing short intervals into one or more virtual constructs that have short size enough to fit into those intervals.

• Journal of IKEEE
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• 제5권1호
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• pp.100-110
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• 2001

In this paper, we investigated several buffer management schemes for the design of shared-memory type ATM switches, which can enhance the utilization of switch resources and can support quality-of-service (QoS) functionalities. Our results show that dynamic threshold (DT) scheme demonstrate a moderate degree of robustness close to pushout(PO) scheme, which is known to be impractical in the perspective of hardware implementation, under various traffic conditions such as traffic loads, burstyness of incoming traffic, and load non-uniformity across output ports. Next, we considered buffer management strategies to support QoS functions, which utilize parameter values obtained via connection admission control (CAC) procedures to set tile threshold values. Through simulations, we showed that the buffer management schemes adopted behave well in the sense that they can protect regulated traffic from unregulated cell traffic in allocating buffer space. In particular, it was observed that dynamic partitioning is superior in terms of QoS support than virtual partitioning.

• Journal of the Korean Association of Geographic Information Studies
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• 제12권3호
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• pp.101-115
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• 2009

The prompt recovery of housing market in Korea became the national task, for which tools that can analyze the influence that changing situation of housing market and new policy may have on the housing market needs to be developed. Thus, this research intends to develop Multi-Agent Housing Market Model and simulation system in Jinju City as a study area. Analyzing the local housing market of Jinju City, then multi-agent model of housing market that consolidates 3 sub-models, house choice model, hedonic model of house price and location choice model is developed. Moreover in order to develop simulation system the model is programmed in the virtual space of which the size is $150{\times}100$ cell including physical shape of city such as road, urban facilities, land use, etc. With the system, simulations are performed to confirm the impact of urban development on the pattern of residential location. As a result, it is found that the residential location can not be easily induced when only road, commercial and convenient facilities are supplied. However, it is also found that since supplying green results in very many residences, arrangement of infrastructure and environmental factor should be considered at the same time for urban development. As conclusion, it is confirmed that the model and simulation system developed in this research smoothly works to be utilized for the analysis of diverse policy experiment and housing market.

• The KIPS Transactions:PartC
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• 제13C권7호
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• pp.889-896
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• 2006

ATM Forum has defined a guaranteed frame rate (GFR) service to serve Internet traffic efficiently. The GFR service provides virtual connections (VCs) for minimum cell rate (MCR) guarantees and allows them to fairly share the residual bandwidth. And ATM Forum has recommended a frame-based generic cell rate algorithm (F-GCRA) as a frame classifier, which determines whether an Am cell is eligible to use the guaranteed bandwidth in a frame level. An ATM switch accommodates cells in its buffer or drops them in a frame level according to current buffer occupancy. A FIFO shared buffer has so simple structure as to be feasibly implemented in switches, but has not been able to provide an MCR guarantee for each VC without buffer management based on per-VC accounting. In this paper, we enhance the F-GCRA frame classifier to guarantee an MCR of each VC without buffer management based on per-VC accounting. The enhanced frame classifier considers burstness of TCP traffic caused by congestion control algorithm so as to enable each VC to use its reserved bandwidth sufficiently. In addition, it is able to alleviate the unfairness problem in usage of the residual bandwidth. Simulation results show that the enhanced frame classifier satisfies quality of services (QoSs) of the GFR service for the TCP traffic.

• Journal of the Korea Academia-Industrial cooperation Society
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• 제20권9호
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• pp.211-226
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• 2019

Pig CD45, the leukocyte common antigen, is encoded by the PTPRC gene and CD45 is a T cell-type specific tyrosine phosphatase with alternative splicing of its exons. The CD45 is a coordinated regulator of T cell antigen receptor (TCR) signal transduction achieved by dephosphorylating the phosphotyrosine of its substances, including $CD3{\zeta}$ chain of TCR, Lck, Fyn, and Zap-70 kinase. A dysregulation of CD45 is associated with a multitude of immune disease and has been a target for immuno-drug discovery. To characterize its key structural features with the effects of regulating TCR signaling, this study predicted the unknown structure of pig CD45RO (the smallest isoform) and the complex structure bound to the ITAM (REEpYDV) of $CD3{\zeta}$ chain via homology modeling and docking the peptide, based on the known human CD45 structures. These features were integrated into the structural plasticity of extracellular domains and functional KNRY and PTP signature motifs (the role of a narrow entrance into ITAM binding site) of the tyrosine phosphatase domains in a cytoplasmic region from pig CD45RO. This contributes to the selective recognition of phosphotyrosine from its substrates by adjusting the structural stability and binding affinity of the complex. The characterized features of pigCD45RO can be applied in virtual screening of the T-cell specific immunomodulator.

• The Journal of the Korea Contents Association
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• 제22권7호
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• pp.55-62
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• 2022

The perovskite solar cell is an active part of research in renewable energy fields such as solar energy, wind, hydroelectric power, marine energy, bioenergy, and hydrogen energy to replace fossil fuels such as oil, coal, and natural gas, which will gradually disappear as power demand increases due to the increase in use of the Internet of Things and Virtual environments due to the 4th industrial revolution. The perovskite solar cell is a solar cell device using an organic-inorganic hybrid material having a perovskite structure, and has advantages of replacing existing silicon solar cells with high efficiency, low cost solutions, and low temperature processes. In order to optimize the light absorption layer thin film predicted by the existing empirical method, reliability must be verified through device characteristics evaluation. However, since it costs a lot to evaluate the characteristics of the light-absorbing layer thin film device, the number of tests is limited. In order to solve this problem, the development and applicability of a clear and valid model using machine learning or artificial intelligence model as an auxiliary means for optimizing the light absorption layer thin film are considered infinite. In this study, to estimate the light absorption layer thin-film optimization of perovskite solar cells, the regression models of the support vector machine's linear kernel, R.B.F kernel, polynomial kernel, and sigmoid kernel were compared to verify the accuracy difference for each kernel function.