• Korean Journal of Acupuncture
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• 제21권4호
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• pp.133-143
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• 2004

Objective : The purpose of this study is to compare the effect of Bee-Venom Therapy and common acupuncture therapy for the acute ankle sprain Methods : This study has been carried out for 32 cases of ankle sprain patients who have visited Cheon-an Oriental Medical Hospital from may 1, 2004 to June 30, 2004. We have treated 16 cases of them by Bee-Venom therapy(group I) and the other 16 cases by common acupuncture therapy(group II). And we have compared those two group. Results and Conclusions : 1. There were good effect on the ankle sprain in both two groups. 2. There were no significant difference at the ROM of ankle joint in both two groups. 3. Common acupuncture therapy had more quick effect on the joint of swelling. 4. In the VAS score, Bee-Venom therapy had more quick effect on total improvement of ankle sprain.

• 한국임상수의학회지
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• 제16권1호
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• pp.150-154
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• 1999

This study was designed to examine the therapeutic effect of Italian honeybee (Apis mellifera) venom in piglets with bacterial diarrhea. Preweaning piglets were assigned to treated and nontreated control groups. In treated group, 47 piglets were given natural honeybee venom once a day for 3 consecutive days. The natural honeybees were stung acupoints of GV-1 (Jiao-Chao, at the indentation between the base of tail and the anus) and ST-25 (Hai-men, about 1 cm lateral to the umbilicus). In control group, 44 piglets were intramuscularly injected with a standard dosage of colistin sulfate (300,000 IU/kg of body weight) and antid-iarrheal drug (berberine, 2 ml/kg) once a day for 3 consecutive days. At post-treatment, 90.9% of control piglets and 93.6 % of piglets in treated group recovered from bacterial diarrhea. Bee acupuncture therapy did not show in piglets without any side effects such as allergy, intoxication, hemorrhage, or infection. It might be concluded that honeybee venom therapy was effective in controlling of piglets with bacterial diarrhea.

• 대한약침학회지
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• 제12권4호
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• pp.127-134
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• 2009

Objective: This case was to report a case of Partial Tear of Triangular Fibrocartilage Complex treated by Intra-articular bee venom Pharmacopuncture. Methods: The patient was treated by Intra-articular bee venom Pharmacopuncture. The Effect of Treatment was evaluated by Visual Analog Scale(VAS) and Modified Mayo Wrist Score(Wrist Score). Results & Conclusions: After Treatment, Patient's VAS decreased and Wrist Score increased. For this results, Intra-articular Bee Venom Pharmacopuncture may be effective for Partial Tear of Triangular Fibrocartilage Complex.

• 대한한방부인과학회지
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• 제29권2호
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• pp.113-120
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• 2016

Objectives: This study aims to report the effects of Korean medicine treatment by pattern identification and Sweet Bee Venom Pharmacopuncture on Chronic Relapsing Cystitis Methods: The patients was treated with Korean medicine by pattern identification and Sweet Bee Venom Pharmacopuncture at Qugu (CV2), Guanyuan (CV4). We evaluated treatment effects by changes of symptoms and urine analysis (UA) finding. Results: After treatments, the clinical symptoms such as painful urination, dysuria, frequent urination were improved and the state of urinalysis was improved. Conclusions: This clinical study suggests that Korean medicine treatment by pattern identification and Sweet Bee Venom Pharmacopuncture are significantly effective in treatment of a Chronic Relapsing Cystitis

• 대한임상독성학회지
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• 제4권1호
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• pp.58-60
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• 2006

The venom gland of Toad contains large quantities of cardiac glycosides, and toad venom poisoning is similar to digitalis toxicity and carries a high mortality. Sometimes after ingestion of aphrodisiac pills which contain dried toad, a patient develops gastrointestinal symptoms and bradycardia, psychoneurologic symptoms. We have experienced 2 cases of toad venom intoxication, who ingested asian toads. Patients were presented to our ED with nausea, vomiting, and abdominal pain. The patients were peformed monitoring and conservative treatment and were fully recovered. Toad venom intoxication should be considered in patients with clinical manifestation of gastrointestinal irritation, cardiac arrhythmias, hyperkalemia, and detectable serum digoxin level without current medication of digoxin.

• Journal of Acupuncture Research
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• 제27권2호
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• pp.155-160
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• 2010

Objectives : The purpose of this study is to investigate the efficacy of Bee venom Pharmarcopuncture on facial palsy in Herpes Zoster otiucus. Methods : We used the acupuncture and Bee venom Pharmarcopuncture complex therapies on facial palsy in Herpes Zoster otiucus occurred in pregnancy. The improvement of the symptom and facial movement was evaluated by VAS and Yanagihara scale. Results & Conclusions : After treatment, both VAS and Yanagihara's scale were significantly improved. In this case, we found that the acupuncture and Bee venom Pharmarcopuncture complex therapy is effective for facial palsy in Herpes Zoster otiucus.

• 한국임상수의학회지
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• 제15권2호
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• pp.247-250
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• 1998

This study was designed to examine therapeutic effect of honeybee venom on wound healing in tail-docked dog. Blood samples were taken of jugular vein and hematological values were analyzed in condition of pre,3- and 6-day after canine caudectomy. Apitherapy group was subcutaneously treated with an Italian honeybee(Apis mellifera ligustica). Antibiotic therapeutic group was intramuscularly iaiected with a standard dosage ol'penicluin ,G procaine(20,000 Units/kg of body weight). Changes of leucocyte, erynlrocytel hematocrit, platelet and fibrinogen were not significantly different between bee sting and penicillin injection during wound healing. No changes of wound healing in tine tests, groups were onseren. Whole honeybee venom has been shown to have a antiinflammatory effect in tail-docked dog. It may be concluded that honeybee venom is effective drug being useful far wound healing and disinfection without tissue trauma in dog.

• 대한예방한의학회지
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• 제20권1호
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• pp.125-144
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• 2016

Objectives : About 13% of the medicines used by traditional korean medicines(TKM), are called animal medicines and are derived from non-herbal sources such as animals and insects. However, the clinical use of these preparations from animal medicines is often based on tradition and belief, rather than on evidence of toxicity and efficacy. As a result, animal medicines containing toxin have caused serious problems from injecting patients with venom. Here, various venoms frequently used as TKM were reviewed in terms of their instinct toxity and tried to estimate their safety classification. Methods : The estimation of safety classification was based on human equivalent dose(HED)-based MOS (margin of safety) and clinical dose applied for patients. Results and Conclusions : Except that of snake venom due to no clinical dose, they were evaluated as class 3 for bee venom, class 4 for cantharidin, toxin from blister beetle, and class 1 for venom from scolopendrid. In conclusion, animal medicines showed a wide range of safety classification from class 1 to class 4. This wide range is estimated to result from extremely limited applications of each venom for patients because of their strong toxicity. However, it should be cautious for application in clinics since animal medicines can produce anaphylactic reactions particularly after veinous administration even with a tiny amount of venom.

• Journal of Acupuncture Research
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• 제23권4호
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• pp.15-20
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• 2006

Objectives : This study was to evaluate the effect of Bee venom-Acupuncture on knee joint with osteoarthritis. Methods : We investigated 30 cases of patients with osteoarthritis of knee joint. We flip a coin and divide into two groups. Bee venom-acupuncture was performed at one group, and the other group didn't do it. We evaluated the treatment effect of each group by using the WOMAC score. Results : 1. As a result of evaluation by using the WOMAC, the score after treatment was marked higher than that before treatment within each group. 2. After treatment, Bee venom-Acupuncture group showed significant difference on WOMAC score compared with acupuncture group. Conclusion : These results suggested that Bee venom-Acupuncture treatment should be more effective in the patient with osteoarthritis of knee joint.

• Journal of Acupuncture Research
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• 제23권4호
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• pp.21-26
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• 2006

Objectives : This study was to evaluate the effectiveness of Bee Venom acupuncture therapy on chronic arthritis of ankle, Methods : We divided chronic arthritis of ankle patient into 2 group; one group combined bee venom acupuncture therapy and acupuncture therapy, another group was only acupuncture therapy. To estimate the efficacy of treatment that applied for two groups, we used visual analog scale(VAS). We compared the VAS score of two groups statistically. Results : 1. As a result of evaluation by using visual analog scale(VAS), treatment score at final was marked more higher than score before treatment on each groups. 2. treatment at final, acupuncture and bee venom acupuncture therapy group had significant result on visual analog scale(VAS) compared with acupuncture therapy group. Conclusion : Bee Venom acupuncture therapy can be used with acupuncture therapy for highly effective treatment for chronic arthritis of ankle.