• Korean Journal of Veterinary Research
• /
• v.56 no.4
• /
• pp.223-227
• /
• 2016

This study evaluated the levels of cardiac biomarkers in dogs with either pulmonic stenosis or aortic stenosis and the correlation between biomarkers and the severity of stenosis assessed by the echocardiography. To achieve this study goal, 38 dogs (10 healthy control dogs, 15 dogs with pulmonic stenosis and 13 dogs with aortic stenosis) were examined. The jet velocity and pressure gradient in this study population were measured by echocardiographic estimation, after which the study group was subdivided by the severity of stenosis. The plasma cardiac troponin I (cTnI) and N-terminal pro-brain natriuretic peptide (NT-proBNP) were measured in this study group. The median concentrations of cTnI and NT-proBNP of the disease group were significantly higher than those of the control group, and these increased gradually as stenosis worsened. The severity of stenosis and the concentrations of cTnI and NT-porBNP were also found to be significantly correlated. Finally, the plasma cTnI and NT-proBNP tests were found to beneficial for differentiating clinical patients, predicting the progression of disease, and monitoring the outcome of interventional therapy for stenosis.

• Transactions of the Korean Society of Mechanical Engineers B
• /
• v.29 no.1 s.232
• /
• pp.110-115
• /
• 2005

A novel technique for fine particle beam focusing under the atmospheric pressure is introduced using a radiation pressure assisted aerodynamic lens. To introduce the radiation pressure in the aerodynamic focusing system, a 25m plano-convex lens having 2.5mm hole at its center is used as an orifice. The particle beam width is measured for various laser power, particle size, and flow velocity. In addition, the effect of the laser characteristics on the beam focusing is evaluated comparing an optical tweezers type and pure gradient force type. For the pure aerodynamic focusing system, the particle beam width was decreased as increasing particle size and Reynolds number. Using the optical tweezers type, the particle beam width becomes smaller than that of the pure aerodynamic focusing system about $16\%,\;11.4\%\;and\;9.6\%$ for PSL particle size of $2.5{\mu}m,\;1.0{\mu}m,\;and\;0.5{\mu}m$, respectively. Particle beam width was minimized around the laser power of 0.2W. However, as increasing the laser power higher than 0.4W, the particle beam width was increased a little and it approached almost a constant value which is still smaller than that of the pure aerodynamic focusing system. For pure gradient force type, the reduction of the particle beam width was smaller than optical tweezers type but proportional to laser power. The radiation pressure effect on the particle beam width is intensified as Reynolds number decreases or particle size increases relatively.

• Nuclear Engineering and Technology
• /
• v.51 no.1
• /
• pp.238-248
• /
• 2019

In the high-temperature and high-pressure irradiation environments, the multi-field coupling processes of hydrogen diffusion, hydride precipitation and mechanical deformation in Zircaloy cladding tubes occur. To simulate this hydrogen-induced complex behavior, a multi-field coupling method is developed, with the irradiation hardening effects and hydride-precipitation-induced expansion and hardening effects involved in the mechanical constitutive relation. The out-pile tests for a cracked cladding tube after irradiation are simulated, and the numerical results of the multi-fields at different temperatures are obtained and analyzed. The results indicate that: (1) the hydrostatic stress gradient is the fundamental factor to activate the hydrogen-induced multi-field coupling behavior excluding the temperature gradient; (2) in the local crack-tip region, hydrides will precipitate faster at the considered higher temperatures, which can be fundamentally attributed to the sensitivity of TSSP and hydrogen diffusion coefficient to temperature. The mechanism is partly explained for the enlarged velocity values of delayed hydride cracking (DHC) at high temperatures before crack arrest. This work lays a foundation for the future research on DHC.

• The Korean Journal of Rheology
• /
• v.10 no.4
• /
• pp.202-216
• /
• 1998

Improved version of previous 'Orthotropic' closure approximation, termed 'ORW' has been numerically developed using new homogeneous flow data. Previous 'Orthotropic' closure approximation, i.e., ORF or ORL showed non-physical oscillation for interaction coefficient $C_1$<0.001 at simple shear flow. It also shows non-physcial oscillation and under-prediction compared with 'Distribution Function Calculation' at non-homogeneous flow of center-gated disk. These phenomena are mainly due to the flow data of 'Distribution Function Calculation' which were used for least-square optimization. ORW obtained by fitting flow data of low interaction coefficient does not show non-physical oscillation and results in reasonably good behaviors at non-homogeneous flows as well as homogeneous flows. Fitting function forms have not been found to improve overall behaviors. It has been found that considering all the eigenvalues of orientation tensor (including the third eigenvalues) might end up with a better closure approximation than just considering the first and second eigenvalues. It is, however, very important and yet difficult to select appropriate function forms of eigenvalues. Numerical simulation including coupling and in-plane velocity gradient effects were performed for injection mold filing process with a film-gated strip and a center-gated disk using ORW and various other closure approximations for comparisons. Although ORW is in excellent agreement with 'Distribution Function Calculation', the predicted results seem to have consistent error in comparison with experimental data. The diffusivity term with constant interaction coefficient might have to be further investigated in order to accurately describe orientation states.

• Journal of Korean Society of Coastal and Ocean Engineers
• /
• v.24 no.6
• /
• pp.390-399
• /
• 2012

This research observed the cross section current of 7 survey lines in Seokmo Channel of Gyeonggi bay with a lot of freshwater inflow and S-shaped for 13 hours during flood season and neap tide. We indicated the distribution of the current velocity by comprehending the speed and direction of the current velocity of each line during maximum flood, ebb tide and observed the distribution of salinity. Moreover, in order to understand what lateral momentum causes the lateral flow in each survey line, we practiced the momentum analysis through the observation data. As a result, the lateral baroclinic pressure gradient force and vertical friction of the Seokmo channel during neap tide were the strongest, and this is why the flow by the distribution of salinity and stratification most often occurs. In north of the Seokmo channel, where have wide intertidal and a lot of freshwater inflow, the secondary circulation is caused by balance of lateral baroclinic pressure gradient force and other forces, and the vertical friction was strong in the lines with small depth. On the other hand, in the southern part of the Seokmo channel where the water is deep and the waterway is curved, the advective acceleration and centrifugal force become stronger by the geographical causes during ebb and the influence of fresh water. Therefore, the lateral flow in the Seokmo channel was caused by the distribution of the momentum that differs by location, depth, curve, etc.

• Journal of the Korean Institute of Gas
• /
• v.15 no.3
• /
• pp.53-57
• /
• 2011

The present study has been carried out to analyze the flow characteristics of a heat recovery steam generator with the change of inlet flow conditions by using numerical flow analysis. The inlet of HRSG corresponds the outlet of gas turbine exit and the flow after gas turbine has strong swirl flow and turbulence. The inlet flow condition of HRSG should be included the exit flow characteristics of gas turbine. The present numerical analysis adopted the flow analysis result of gas turbine exit flow as a inlet flow condition of HRSG analysis. The computational flow analysis result of gas turbine exit shows that the maximum axial velocity appears near circular duct wall and the maximum turbulent kinetic energy and dissipation rate exist relatively higher gradient region of axial velocity. The comparison of flow analysis will be executed with change of inlet turbulent flow condition. The first case is using the inlet turbulent properties from the result of computational analysis of gas turbine exit flow, and the second case is using the assumed turbulent intensity with the magnitude proportional to the velocity magnitude and length scale. The computational results of flow characteristics for two cases show great difference especially in the velocity field and turbulent properties. The main conclusion of the present study is that the flow inlet condition of HRSG should be included the turbulent properties for the accurate computational result of flow analysis.

• Korean Journal of Materials Research
• /
• v.5 no.2
• /
• pp.251-258
• /
• 1995

In an effort to increase the thermoelectric figure of merit by reducing the thermal conductivity, the unidirectionally solidified n-type (Bi, Pb)-Te based alloys which form a $Bi_{2}Te_{3}-PbBi_{4}Te_{7}$eutectic lamellar structure were investigated with the microstructural control at various solidification conditions. PbBi_{4}Te_{7}$ lamellae were grown on cleavage plane(0001) of $Bi_{2}Te_{3}$ and the interlamellar spacing decreased from 10.4 $\mu \textrm{m}$to 3.2$\mu \textrm{m}$ with growth velocity variation from 1.4 \times 10^{-4}$cm/sec to $8.3 \times 10^{-4}$cm/sec. Seebeck coefficient was constant, $\mid$$\alpha$$\mid$=29 $\mu$ V/K regardless of growth direction, growth velocity and temperature gradient. Electrical conductivity showed a tendency to decrease slightly with growth velocity and it parallel to growth direction was about three times as large as perpendicular direction. The figures of merit were varied differently from Seebeck coefficients and electrical conductivities depending on the growth direction, growth velocity and temperature gradients. They showed the relative increase in case of perpendicular direction compared with parallel to growth direction. It is believed to be due to the reduction of the thermal conductivity according to decrease of the interlamellar spacing.

• Journal of the Korean Society for Aeronautical & Space Sciences
• /
• v.47 no.12
• /
• pp.904-912
• /
• 2019

We have studied the numerical analysis about the fragment ejection velocity and spray angle when the High Explosive warhead detonated at proximity distance at an aircraft. To study the physical quantities about the warhead components is very important to assessment the vulnerability of aircraft. Generally, the physical quantities about the components of a warhead such as the mass, length, diameter and charge to mass ratio are unknown. Therefore, it is required to estimate the physical quantities by using physical continuities of similar threats. The empirical formulas to understand the dependence among charge to mass ratio, length and diameter ratio were driven by using the physical parameters of similar threatening such as terrier, sparrow. As a result, we confirmed that the dead mass ratio was closed to 20% of warhead mass since the metal case of the proximity threat acts as a simple carrier. This implies that the effective length and diameter of High Explosive Compound is smaller than the length and diameter of warhead, and become a key to understand the large ejection gradient velocity and small spray angle of fragments within 6 degree.

• Korean Circulation Journal
• /
• v.53 no.11
• /
• pp.744-755
• /
• 2023

Background and Objectives: Aortic valve replacement (AVR) is considered a class I indication for symptomatic severe aortic stenosis (AS). However, there is little evidence regarding the potential benefits of early AVR in symptomatic patients diagnosed with normal-flow, low-gradient (NFLG) severe AS. Methods: Two-hundred eighty-one patients diagnosed with symptomatic NFLG severe AS (stroke volume index ≥35 mL/m², mean transaortic pressure gradient <40 mmHg, peak transaortic velocity <4 m/s, and aortic valve area <1.0 cm²) between January 2010 and December 2020 were included in this retrospective study. After performing 1:1 propensity score matching, 121 patients aged 75.1±9.8 years (including 63 women) who underwent early AVR within 3 months after index echocardiography, were compared with 121 patients who received conservative care. The primary outcome was a composite of all-cause death and heart failure (HF) hospitalization. Results: During a median follow-up of 21.9 months, 48 primary outcomes (18 in the early AVR group and 30 in the conservative care group) occurred. The early AVR group demonstrated a significantly lower incidence of primary outcomes (hazard ratio [HR], 0.52; 95% confidence interval [CI], 0.29-0.93; p=0.028); specifically, there was no significant difference in all-cause death (HR, 0.51; 95% CI, 0.23-1.16; p=0.110), although the early AVR group showed a significantly lower incidence of hospitalization for HF (HR, 0.43; 95% CI, 0.19-0.95, p=0.037). Subgroup analyses supported the main findings. Conclusions: An early AVR strategy may be beneficial in reducing the risk of a composite outcome of death or hospitalization for HF in symptomatic patients with NFLG severe AS. Future randomized studies are required to validate and confirm our findings.

• Journal of the Korean Society of Propulsion Engineers
• /
• v.3 no.2
• /
• pp.10-17
• /
• 1999

This paper investigates the linear stability of both uniform and non-uniform density plane mixing layers with special emphasis on the effect of the wake component in the velocity profile. Velocity and density profiles for laminar flows are obtained from analytic profiles. Mixing layers with wakes have two generalized inflection points and two unstable modes-sinuous and varicose modes. For uniform density mixing layers, sinuous modes are more unstable than varicose modes, which shows wakes will be destabilized by sinuous modes. For non-uniform density mixing layers with high density in high speed flows, sinuous modes are more unstable than varicose modes. For non-uniform density mixing layers with high density in low speed flows, varicose modes can be more unstable than sinuous modes.