• 한국식품과학회지
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• 제19권4호
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• pp.346-354
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• 1987

국내 mandarin감귤중 만생종으로 대표적인 임온주 및 청도품종과 valencia sweet orange의 향기성분을 capillary GC와 GC/MS에 의해 분석하여 mandarin으로부터 탄화수소류 11종, 알코올류 10종, 알데하이드류 4종, 에스테르 1종, 기타 5종등 31종을 확인 하였으며, sweet orange에서는 탄화수소류 12종, 알코올류 11종, 알데하이드류 8종, 에스테르 1종, 기타 5종등 37종을 확인 하였다. 이들 중 limonene이 62.63, 88.56%로 대부분을 차지하고 있으며 sweet orange에 23.93%나 많이 함유하고 있다. 이외 mandarin에는 octanal, terpineol, styrene, d-citronellol, farnesol, ${\alpha}-pinene$, ${\alpha}-terpinene$, e-cadiene, citronellal, cis-carveol등이 있고 sweet orange에는 myrcene, elemene, decanol, terpineol, terpinolene, linalool, d-citronell등이 있음을 확인하였다.

• The Korean Journal of Physiology and Pharmacology
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• 제25권1호
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• pp.87-94
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• 2021

Skin photoaging occurs due to chronic exposure to solar ultraviolet radiation (UV), the main factor contributing to extrinsic skin aging. Clinical signs of photoaging include the formation of deep, coarse skin wrinkles and hyperpigmentation. Although melanogenesis and skin wrinkling occur in different skin cells and have different underlying mechanisms, their initiation involves intracellular calcium signaling via calcium ion channels. The ORAI1 channel initiates melanogenesis in melanocytes, and the TRPV1 channel initiates MMP-1 production in keratinocytes in response to UV stimulation. We aimed to develop a drug that may simultaneously inhibit ORAI1 and TRPV1 activity to help prevent photoaging. We synthesized nootkatol, a chemical derivative of valencene. TRPV1 and ORAI1 activities were measured using the whole-cell patch-clamp technique. Intracellular calcium concentration [Ca2+]i was measured using calcium-sensitive fluorescent dye (Fura-2 AM). UV-induced melanin formation and MMP-1 production were quantified in B16F10 melanoma cells and HaCaT cells, respectively. Our results indicate that nootkatol (90 μM) reduced TRPV1 current by 94% ± 2% at -60 mV and ORAI1 current by 97% ± 1% at -120 mV. Intracellular calcium signaling was significantly inhibited by nootkatol in response to ORAI1 activation in human primary melanocytes (51.6% ± 0.98% at 100 μM). Additionally, UV-induced melanin synthesis was reduced by 76.38% ± 5.90% in B16F10 melanoma cells, and UV-induced MMP-1 production was reduced by 59.33% ± 1.49% in HaCaT cells. In conclusion, nootkatol inhibits both TRPV1 and ORAI1 to prevent photoaging, and targeting ion channels may be a promising strategy for preventing photoaging.

• Journal of the Korean Wood Science and Technology
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• 제51권3호
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• pp.207-221
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• 2023

The increasing demand for clean energy requires considerable effort to find alternative energy sources, such as briquettes. This research aims to develop a charcoal briquette with added pine resin (API) that has excellent combustion speed and distinctive aroma. Briquettes are composed of charcoal, pine resin (concentration: 0%-30%), and starch (up to 7%). They are produced in several stages, including coconut shell pyrolysis in conventional combustion, to obtain charcoal for the briquette precursor. Briquette compaction is conducted by mixing and densifying the charcoal, pine resin, and starch using a hydraulic press for 3 min. The hydraulic press has a total surface area and diameter of 57.7 cm² and 3.5 cm, respectively. The briquettes are dried at different temperatures, reaching 70℃ for 24 h. The study results show that the briquettes have a thickness and diameter of up to 2 and 3.5 cm, respectively; moisture of 2.18%-2.62%; ash of 11.61%-13.98%; volatile matter of 27.15%-51.74%; and fixed carbon content of 40.24%-59.46%. The compressive strength of the briquettes is 186-540 kg/cm². Their calorific value is 5,338-6,120 kcal/kg, combusting at a high speed of 0.15-0.40 s. The methoxy naphthalene, phenol, benzopyrrole, and lauryl alcohol; ocimene, valencene, and cembrene are found in the API. The API briquette has several chemical compounds, such as musk ambrette, ocimene, sabinene, limonene, 1-(p-cumenyl) adamantane, butane, and propanal, which improve aroma, drug application, and fuel production. Accordingly, API briquettes have considerable potential as an alternative energy source and a health improvement product.