• 한국식품조리과학회지
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• 제11권2호
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• pp.119-121
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• 1995

쇠고기를 양념하여 구워서 조리식품으로 만들 때 사용하는 부가재료 중 생강이 고기에 미치는 영향을 연구한 결과 다음과 같은 것을 알 수 있었다. \circled1고기를 재울때 소금을 넣지 않고 생강즙을 0.5~l.0%까지 넣어 자작하니 재워두었다가 구운 고기는 20~30%까지 부드럽게 개선되었고 소금을 2% 첨가하고 생강즙을 넣은 고기는 35~45%까지 부드러워 졌다. \circled7 생강즙은 실험결과 고기의 산패를 늦추어 주었고 생강즙을 넣어 조리해서 Saran-Wrap을 가지고 2겹으로 포장해서 보관하거나 Vacuum처리하면 보존기간이 길게 되었다. \circled3생강즙은고기의 질을 연하게 하였고 특히 진공포장을 하지 않고도 조리식품으로 만들어진 제품으로 사용하기가 매우 편리할 것으로 생각된다.

• Natural Product Sciences
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• 제8권3호
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• pp.97-99
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• 2002

In the present study, Pisonia grandis leaves were extracted with chloroform and methanol. The extracts were vacuum dried to yield the respective chloroform (CE) and methanol extract (ME). CE and ME were evaluated for analgesic, anti-inflammatory (acute and chronic) and diuretic activity at 2 dose levels (250 and 500 mg/kg). Significant analgesic and anti-inflammatory activities were associated with CE and ME. CE at the dose level of 500 mg/kg was found to exhibit equivalent chronic anti-inflammatory activity as diclofenac at 50 mg/kg dose level. Significant diuretic activity was exhibited by ME. Graded dose response for all the activities were observed for the extracts.

• Journal of Biosystems Engineering
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• 제33권5호
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• pp.333-339
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• 2008

The purpose of this study was to develop a portable electronic nose system to measure volatile components of agricultural and food products. Also, a graphical operating software to control the electronic nose system and to acquire signals through the Internet was developed. An array of five commercial metal oxide gas sensors was used to detect various volatile gas components of target samples. Transient and steady state signals were analyzed to extract variables related to sample states, To find optimal operating conditions of the system, several experiments were performed with different gas chambers, vacuum pumps, gas sampling temperatures, and sample container sizes. The patterns of gas sensor signals were analysed to find effects of the various conditions.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1998년도 Proceedings of UNESCO-internetwork Cooperative Regional Seminar and Workshop on Bioassay Guided Isolation of Bioactive Substances from Natural Products and Microbial Products
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• pp.169-169
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• 1998

Three analgesic constituents: FB2c, FB6Fc, and FB10E5c from the hexane extract of Mentha cordifolia Opiz. (Yerba buena) leaves were isolated by solvent partitioning and sequential repeated vacuum liquid chromatography. Spectral analysis of the three constituents show that FB2c is ${\beta}$-sitosterol; FB10E5c is ${\beta}$-sitosteryl-${\beta}$-D-glucopyranoside; and FB6Fc is a cis-8- pentadecenyl with lactone variety. At a dosage of 100 mg/kg mouse, isolates FB2c, FB6Fc, and FB10E5c decreased the number of squirms induces by acetic acid by 70.0 %, 67.3 %, and 73.0 %, respectively.

• Journal of Ginseng Research
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• 제6권2호
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• pp.115-122
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• 1982

This studies were conducted to investigate the effect of extraction and evaporating conditions on the free sugar in ginseng extracts. Raw ginseng roots were extracted with water or various concentration of water-ethanol solutions. Then the extracts were evaporated by boiling or vacuum evaporated at 50 $^{\circ}C$ and 70 $^{\circ}C$. The results are as follows Sucrose and maltose contents were 7.95% and 12.8% in water extracts and 19.96%, 0.34-0.93% in 90% ethanol extracts, respectively. On the otherhand, glucose and fructose contents were not affected by the solvents. Evaporating conditions, such as temperature, were rarely effected to the sugar contents.

• 약학회지
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• 제37권4호
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• pp.356-361
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• 1993

A sensitive method for the determination of methamphetamine(MA) and amphetamine(AM) in hair was developed by gas chromatography/mass spectrometry using stable isotope-labeled internal standards, amphetamine-d$_{5}$ and methamphetamine-d$_{5}$. Hair sample was washed with MeOH, incubated with MeOH(I% HCI) overnight at $37^{\circ}C$ while stirring and extracted using solid phase extraction column on a vacuum manifold. The extract obtained was pentafluoropropionated, and applied to GC/MS. The calibration curves of MA and AM were linear from 2.5 to 250 ng (r>0.99 for both). The limit of detection was 0.1 ng/mg in hair and cut-off level was set at 0.25 ng/mg for both. Hair samples of 27 MA abusers showed positive results in the range 0.7 to 106.8 ng/mg. AM, its metabolite, was detected in 20 out of 27 samples. The ratio of MA versus AM was 4.6~38.3 in specimens. Hair analysis for methamphetamine by GC/MS is an effective method for identifying long-term drug abusers.

• 한국균학회지
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• 제11권4호
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• pp.147-150
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• 1983

To investigate a possibility of producing the antitumor component by shake culture method, the mycelia of Flammulina velutipes were cultured in flasks on a shaker at $26{\sim}28^{\circ}C$ at 180 rpm for seven days. The extract of the mycelia was concentrated under vacuum. The precipitate obtained by adding a three-fold volume of ethanol was centrifugated and freeze-dried after dialysis. The fraction was tested against sarcoma 180 in the mice. The inhibition ratio of the fraction against the tumor was 68.0% at the dose of 20 mg/kg/day for the period of ten days and the tumors in three of the mice were completely regressed. The results showed, therefore, that the antitumor component was produced by the shake culture method.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2014년도 제46회 동계 정기학술대회 초록집
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• pp.411.1-411.1
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• 2014

This study evaluates the utility of an antibacterial microneedle composed of green tea extract (GT) and hyaluronic acid (HA), for the efficient delivery of GT. These microneedles have the potential to be a patient-friendly method for the conventional sustained release of drugs. In this study, a fabrication method using a mold-based technique to produce GT/HA microneedles with a maximum area of ${\sim}60mm^2$ with antibacterial properties was used to manufacture transdermal drug delivery systems. Fourier transform infrared (FTIR) spectrometry was carried out to observe the potential modifications in the microneedles, when incorporated with GT. The degradation rate of GT in GT/HA microneedles was controlled simply by adjusting the HA composition. The effects of different ratios of GT in the HA microneedles were determined by measuring the release properties. In HA microneedles loaded with 70% GT (GT70), a continuous higher release rate were sustained for 72 h. The in vitro cytotoxicity assays demonstrated that GT/HA microneedles are not generally cytotoxic to chinese hamster ovary cells (CHO-K1), human embryonic kidney cells (293T), and mouse muscle cells (C2C12), which were treated for 12 and 24 h. Antimicrobial activity of the GT/HA microneedles was demonstrated by ~95% growth reduction of gram negative [Escherichia coli (E. coli), Pseudomonas putida (P. putida) and Salmonella typhimurium (S. typhimurium)] and gram positive bacteria [Staphylococcus aureus (S. Aureus) and Bacillus subtilis (B. subtilis)], with GT70. Furthermore, GT/HA microneedles reduced bacterial growth in the infected skin wound sites and improved skin wound healing process in rat model.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2014년도 제46회 동계 정기학술대회 초록집
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• pp.366.2-366.2
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• 2014

Impedance spectroscopy allows for simultaneous characterization of interface-controlled materials and/or devices in terms of electrical and dielectric aspects. Recently, there have tremendous interests in 2-dimensional electron gas layers (2DEGs) involving $LaAlO_3$ and $SrTiO_3$ whose features incorporates extremely high mobility and carrier concentrations along with metallic responses unlike the constituents, $LaAlO_3$ and $SrTiO_3$. Impedance spectroscopy offers the following unique features, such as simultaneous determination of conductivity and dielectric constants, identification of electrical origins among bulk-, grain boundary-, and electrode-based responses. Impedance spectroscopy was applied to the 2DEG $LaAlO_3/SrTiO_3$ system, in order to extract the electrical and dielectric information operating in the 2DEG system. The unique responses of the 2DEG system are investigated in terms of temperature and device structures. The underlying mechanism of the 2DEG system is proposed with the aim to optimizing the high-mobility 2DEG responses and to expedite the associated devices towards the high-density integrated chips.

• 한국진공학회지
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• 제17권3호
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• pp.234-239
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• 2008

휴대용 XRF (X-Ray Fluorescence) 장치에 적용할 수 있는 40 kV용 투과 양극형 W-Target tube와 Rh-Target tube를 개발하고 특성을 조사하였다. 특성 x-ray의 에너지와 연속 x-ray의 선량특성은 알려진 결과와 잘 일치함을 확인하였고, 최대 선량을 추출하기 위한 양극금속 박막의 최적 두께는 W-target tube의 경우 약 $2.6{\mu}m$, Rh-target tube의 경우 약 $2.7{\mu}m$ 임을 밝혀내었다. 또한 관전압 40 kV, 관전류 $60{\mu}A$로 30분 동안 연속적으로 작동시켰을 때 양극에서의 온도는 $50^{\circ}C$를 넘지 않아 휴대용 XRF장치에 적용할 수 있음을 확인하였다.