• Title/Summary/Keyword: vaccination effect

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A Generalized Mixed-Effects Model for Vaccination Data

  • Choi, Jae-Sung
    • Journal of the Korean Data and Information Science Society
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    • v.15 no.2
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    • pp.379-386
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    • 2004
  • This paper deals with a mixed logit model for vaccination data. The effect of a newly developed vaccine for a certain chicken disease can be evaluated by a noninfection rate after injecting chicken with the disease vaccine. But there are a lot of factors that might affect the noninfecton rate. Some of these are fixed and others are random. Random factors are sometimes coming from the sampling scheme for choosing experimental units. This paper suggests a mixed model when some fixed factors need to have different experimental sizes by an experimental design and illustrates how to estimate parameters in a suggested model.

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The Effect of Feeding Mannan-Oligosaccharides (Bio-MOS) on the Performance of Meat Chickens under Two Different Vaccination Programs

  • Shafey, T.M.;Al-Mufarej, S.;Shalaby, M.I.;Jarelnabi, A.J.
    • Asian-Australasian Journal of Animal Sciences
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    • v.14 no.4
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    • pp.559-563
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    • 2001
  • The effects of feeding a mannan oligosaccharide (Bio-Mos) from 0 to 3 g/kg diet and vaccination program on 1- to 35-day performance (growth and feed efficiency), metabolizable energy, nitrogen utilization and carcass composition of meat chickens were investigated. A general vaccination program was used against IB, IBD and ND with half of the birds per diet receiving a booster dose of IB and ND vaccines at 12 days of age. Dietary supplementation of Bio-Mos (BM) did not influence body weight gain, feed efficiency and nutrient utilization. The highest dietary BM (3 versus 1.5 or 0 g/kg) increased carcass abdominal fat and reduced the proportion of drumstick in the carcass of meat chickens. The booster dose reduced the performance of birds. It was concluded that the addition of BM to the diet of chickens did not significantly influence the performance and nutrient utilization of meat chickens.

Is Postoperative Isoniazid Therapy Necessary for Regional Lymphadenitis Following BCG Vaccination? (BCG 접종후 발생한 림프선염의 외과적 치료후 Isoniazid 투여의 필요여부)

  • Shin, Kwan-Soo;Lee, Nam-Hyuk;Kim, Sang-Youn
    • Advances in pediatric surgery
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    • v.3 no.1
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    • pp.1-5
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    • 1997
  • Regional lymphadenitis is the most common complication following BCG vaccination in this country. The literature describes controversial results with medical, surgical and combined therpy. The purpose of this study is to clarify the therapeutic effect of isoniazid(INH) after surgical procedures. The early and late postoperative complications of 136 children with lymphadenitis following BCG vaccination at the Taegu Fatima Hospital between March 1985 and February 1996 were reviewed. In 90 children, INH was given for 3-4 days before operation and for 3 months after surgery. In the other 46 cases, INH was not given during the pre- or postoperative period. Surgical procedures were excision or incision and currettage according to the states of lesions. Postoperative complications were fluid accumulation, wound infection, sinus formation and others. Complication rates were 14.4 % in INH-treated group and 13.0% of INH-nontreated group. The difference was not significant. There was no recurrence or other late complication in either groups. The result suggest that surgical excision or incision and currettage are sufficient for the treatment of regional lymphadenitis following BCG vaccination and postoperative INH therapy is not necessary.

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A study on the mathematical model of an influenza system control (인플루엔자 류행 관리의 수학적 모델화)

  • 정형환;박상희
    • 전기의세계
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    • v.30 no.3
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    • pp.167-171
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    • 1981
  • In this paper, the mathematical model of influenza derived by the state space method induced a new model by using normal distribution curve of incubation period and researched the effect of vaccination. The important results are as follows. (1) A new model represents accurate spread curve. (2) The standard deviation period in Korea is about 1.5 degree. (3) The number of carries of influenza since put in practice to the vaccination 20% is reduced by average 9.8% degree, the period of spread increase 4 days degree. (4) The vaccination at early put in operation was far surperior and the period of spread grow longer more or less. (5) In the first stage of an attack of disease a case increase since reducing. (6) The number of carries at night is reduced by average 5.468% than in the daytime.

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COVID-19 Vaccination for Pilots and Air Traffic Controllers (항공종사자와 코로나바이러스감염증-19 백신 예방 접종)

  • Kwon, Young Hwan
    • Korean journal of aerospace and environmental medicine
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    • v.31 no.1
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    • pp.13-16
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    • 2021
  • The coronavirus disease-19 (COVID-19) vaccine is expected to play an important role in stopping the pandemic. Studies show that COVID-19 vaccines are effective at keeping you from getting COVID-19. Getting a COVID-19 vaccine will also help keep you from getting seriously ill even if you do get COVID-19. Efforts to find an effective vaccine against severe acute respiratory syndrome coronavirus 2 have progressed unprecedentedly through active support from public research grants and private-public partnership programs. Clinical studies have been actively conducted, and some vaccines are being vaccinated with approval for urgent use. The WHO has approved and supplied the Pfizer-BioNTech COVID-19 vaccine and the Oxford-AstraZeneca COVID-19 vaccine. In Korea, the Oxford-AstraZeneca vaccine was approved for urgent use, and vaccination began on February 26, 2021. In this paper, the efficacy and side effects of each vaccines and the effect on pilots and air traffic controllers related to COVID-19 vaccination were investigated in terms of aviation medicine.

AN SEIR ENDEMIC MODEL FOR MONKEYPOX SPREAD IN UNITED STATES

  • S. SHALINI PRIYA;K. GANESAN
    • Journal of applied mathematics & informatics
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    • v.41 no.5
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    • pp.1017-1035
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    • 2023
  • In this paper, we construct a monkeypox model which is similar to smallpox infection. It is caused by a monkeypox virus which is related to Poxviridae family. It will occur mostly in West African communities and in remote Central. We develop a system of differential equations for an SEIR (Suspected, Exposed, Infected and Recovered) model and analyze the outbreak of monkeypox disease and its effect on United States(US) population. We establish theorems on asymptotical stability conditions for endemic equilibrium and disease-free equilibrium. The basic reproduction number R0 has been determined using next generation matrix. We expect that this study will be effective at controlling monkeypox spread in United States. Our goal is to see whether monkeypox can be controlled and destroyed by smallpox vaccination. We find that monkeypox is controllable and can be fully destroyed in disease free state by vaccination. However, in the endemic state, monkeypox cannot be destroyed by vaccination alone.

COVID-19 Death and BCG Vaccination Programs Worldwide

  • Jirjees, Feras J.;Bashi, Yahya H. Dallal;Al-Obaidi, Hala J.
    • Tuberculosis and Respiratory Diseases
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    • v.84 no.1
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    • pp.13-21
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    • 2021
  • Several clinical trials are being conducted worldwide to investigate the protective effect of the bacillus Calmette-Guérin (BCG) vaccine against death in healthcare providers who are working directly with coronavirus disease 2019 (COVID-19) patients. Clinical studies suggested that certain live vaccines, particularly the BCG vaccine, could reduce the mortality due to other diseases caused by non-targeted pathogens, most probably through the nonspecific effects (heterologous effects). By the end of May 2020, the available information on the COVID-19 pandemic indicated the great effect of the BCG vaccine in reducing the number of COVID-19 death cases. The occurrence of death due to COVID-19 was found to be 21-fold lower in countries with a national BCG vaccination policy than in countries without such a policy, based on the medians of COVID-19 death case per 1 million of the population in these two groups of countries (p<0.001, Mann-Whitney test). Therefore, it can be concluded that the early establishment of a BCG vaccination policy in any country is a key element in reducing the number of COVID-19 and tuberculosis death cases.

Factors Related to COVID-19 Vaccination Intention Based on Theory of Planned Behavior in Convergence Era (융합 시대의 계획된 행위이론에 근거한 COVID-19 예방접종 행위의도 관련요인)

  • Choi, Won-Hee;Je, Nam-Joo;Seo, Yeong-Mi;Lee, Do-Young
    • Journal of Digital Convergence
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    • v.19 no.9
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    • pp.229-239
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    • 2021
  • This study is to identify the factors influencing the attitudes, behavior controls, and subjective norms related to COVID-19 vaccination on the intention of preventive behavior in K provincial residents. A total of 232 people agreed to participate in the study. Data were analyzed using descriptive statistics, t-test, ANOVA, correlation, and Hierarchical analysis. As a result of this study, the factors that had a statistically significant effect on the intention to conduct COVID-19 vaccination were perceived behavioral control (β=.39, p<.001) and attitude toward COVID-19 preventive behavior (β=.24, p<.001), followed by subjective norm (β=.24, p<.001). The explanatory power for this was 56.8%. The COVID-19 vaccine is an important means of ending the COVID-19 pandemic and helps prevent infection or worsening of COVID-19 and protect those around you. In the post-COVID-19 situation, it is necessary to improve the intention of vaccination against COVID-19 and to take active measures and strategies. At this point in time when COVID-19 vaccination is becoming more prevalent across the country, we hope that the intent of the COVID-19 vaccination action will translate into a COVID-19 vaccination action.

Protective effects and immunogenicity of Salmonella Enteritidis killed vaccine strains selected from virulent Salmonella Enteritidis isolates (Salmonella Enteritidis 분리주에서의 선발된 불활화 백신균주의 방어효과 및 면역원성)

  • Kang, Zheng-Wu;Won, Ho-Keun;Kim, Eun-Hee;Noh, Yun-Hee;Choi, Hwan-Won;Hahn, Tae-Wook
    • Korean Journal of Veterinary Research
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    • v.51 no.1
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    • pp.21-28
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    • 2011
  • Salmonella Enteritidis (SE) has been a major causative agent of food-borne human disease due to consumption of contaminated eggs and poultry meat. To prevent SE infection in poultry, and therefore minimize human infections, vaccination with either killed or live SE vaccine is suggested. We evaluated a newly developed killed bacterin using a representative SE isolate in Korea. Among pool of SE isolates, two highly virulent isolates (the one isolate from chicken, the other from human) were selected by measuring mortality in mouse and chickens administered. The chickens were injected intramuscularly with killed vaccine and were challenged with highly virulent SE strain 3 week after vaccination. The recovered colony count (cfu/g) of spleen and cecal content in the vaccinated groups was reduced compared with those of the unvaccinated control group. The antibody level in the vaccinated groups was higher at 3 week post vaccination. These results indicate that vaccination with killed vaccine was effective in preventing the infection of virulent SE. Further study for a large number of layers should be needed for the effect of egg production, SE shedding in feces, persistence of antibody level.

Updated Theory of Planned Behavior in Predicting Parents' Intentions to Vaccinate Their Sons in Elementary School against Human Papillomavirus (초등학생 아들에 대한 부모의 인유두종바이러스 백신접종 의도와 예측요인: 개정된 계획된 행위이론의 적용)

  • Kang, Eun Hee;Lee, Eun-Hyun
    • Research in Community and Public Health Nursing
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    • v.32 no.2
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    • pp.195-204
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    • 2021
  • Purpose: This study was to determine how attitude, subjective norm, and perceived behavioral control (PBC) were related to parents' intentions to vaccinate their sons in elementary school against human papillomavirus (HPV), applying the updated theory of planned behavior. Two hypotheses were examined: PBC would moderate the relationship of attitude to intention and subjective norm to intention, respectively. Methods: This was a cross-sectional study with 231 participants recruited in November, 2018. Inclusion criteria for the participants were parents with 5th-6th grade boys in elementary schools. The moderation effects of the hypotheses were analyzed using the PROCESS macro for SPSS. Results: PBC significantly moderated the relationship of attitude to intention on HPV vaccination. The simple effect of attitude to intention was significant under three different levels of the PBC (low, moderate, and high), but the magnitudes of the relationships were not homogeneous. The magnitude of the relationship between attitude and intention was the lowest for the parents with the low level of the PBC. In the relationship of subjective norm to intention on HPV vaccination, the moderating effect of the PBC was not supported. Subjective norm and PBC directly predicted the intention on HPV vaccination. Conclusion: In order to promote the parents' intentions to vaccinate their sons in elementary school against HPV, we need a program that can improve parents' attitude, subjective norm, and PBC, requiring special attention to the parents with the low PBC.