• The Journal of Korean Obstetrics and Gynecology
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• v.18 no.3
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• pp.215-224
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• 2005

Purpose : Endometrial hyperplasia(EH) is an abnormal proliferation of the glandular component of the endometrium. And also EH is relateted to endometrial carcinoma clinically. Hysterectomy is the common treatment for EH patients in western medicine, but this treatment is the invasive treatment for women. The purpose of this study is to report the effect of oriental treatment for an abnormal uterine bleeding owing to endometrial hyperplasia. Methods : This study is about metrorrhagia owing to EH for three years. This report is performed to observe medication of Guichulpajing-tang(歸朮破?湯) diagnosed as blood stasis in oriental medicine view. Results : The uterine bleeding of the EH was reduced gradually during first menstual cycle and was not repeated. The uterine bleeding disappered from the next menstual cycle. Furthermore, the BBT has been stable during 2 menstual cycles and endometrial thickness has been thined remarkably by pelvic sonogram. Conclusion : This case showed successful oriental herbal medication for EH and further study will be investigated in oriental medicine for treatment of EH completely.

• Journal of Sasang Constitutional Medicine
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• v.22 no.2
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• pp.108-114
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• 2010

1. Objectives: The purpose of this case is to report the effect of Onbaek-won(溫白元) which is based on Sasang Constitutional Medicine for abnormal uterine bleeding from Endometriosis in Soeumin. 2. Methods: We treated Soeumin patient that had abnormal uterine bleeding from endometriosis. We prescribed Onbaek-won(溫白元) for her physical symptoms. The improvement of her disease was checked her bleeding volume and other physical symptoms. 3. Results: After the Sasang constitutional medication of Onbaek-won(溫白元) was given, her bleeding volume and her physical symptoms was improved. 4. Conclusions: This case study show an efficient result of using Onbaek-won(溫白元) in abnormal uterine bleeding from endometriosis of Soeumin. Onbaek-won(溫白元) was used instead of Semen Tiglii(巴豆).

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.5
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• pp.1427-1432
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• 2005

The purpose of this study is to report the effect of oriental treatments for the abnormal uterine bleeding. We treated 10 outpaients who had abnormal uterine bleeding and visited Dongshin University Oriental Medical Hospital by Herb medication, acupuncture therapy and moxibustion therapy at the same time in accordance with 塞流 ([sailiu]-stanch blood), 澄源([chengyuan]-correct origin) and 復舊([fujiu]-restore) which are principles of treatment of 崩漏 ([benglou]-metrorrhagia) and got good results from them. in herbal medication Yikweseungyang-tanggamibang or Junsaenghwalhyul-tanggamibang was used. In acupuncture therapy, Sp10(Hyulhae, 血海) K10(Umgok, 陰谷) Sp6(Samumgyo, 三陰交) Liv2(Haenggan, 行間) Liv3(Taechung, 太衝) CV3(Chungguk, 中極) were used. In Moxa Therapy, Sp6(Samumgyo, 三陰交) CV6(Qihae, 氣海) CV4(Kwanwon, 關元), CV3(Chungguk, 中極) were used. After the oriental medical treatments, abnormal uterine bleeding was disappeared and 10 outpaients recovered the normal menstrual cycle. This study showed successful orieantal herbal treatment of metrorrhagia. After this, further study and approach will be needed about the disease of the abnormal uterine bleeding.

• Journal of the Korean Society of Radiology
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• v.83 no.3
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• pp.699-704
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• 2022

Acute puerperal uterine inversion is a rare postpartum obstetric complication; however, without rapid diagnosis and appropriate management, it is life-threatening. Substantial bleeding hinders the verification of a partially inverted uterus, possibly delaying the treatment. Herein, we present the report of a 32-year-old female presenting with massive postpartum bleeding managed by uterine artery embolization. The peculiar course of the uterine artery bowing inferiorly along the inverted fundus during embolization could uncover the uterine inversion, which was not diagnosed by physical examination and CT. In conclusion, uterine artery embolization is not only an effective therapeutic strategy for postpartum hemorrhage but also a valuable tool for diagnosing uterine inversion.

• Korean Journal of Acupuncture
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• v.19 no.2
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• pp.133-148
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• 2002

This study was designed to investigate acupunture and moxibustion for uterine bleeding through literature research. We extracted the parts about acupunture, moxibustion and both of acupunture and moxibustion for uterine bleeding from ancient and modern oriental medical literature. The results were summerized as follows; 1. The acupoints used on acupunture only were 58 acupoints. The acupoints used often were SP6, LR3, SP10, CV3, CV6 in order and the meridians used often were SP, CV, LV, KI in order. 2. The acupoints used on moxibustion only were 38 acupoints. The acupoints used often were SP10, SP1, SP6, CV4, CV6 in order and the meridians used often were SP, CV, KI, GV in order. 3. The acupoints used on both of acupunture and moxibustion were 22 acupoints. The acupoints used often were SP6, LR3, SP10, KI10 in order and the meridians used often were LV, SP, KI in order.

• The Journal of Korean Obstetrics and Gynecology
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• v.18 no.3
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• pp.250-257
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• 2005

Purpose : This study was designed to evaluate the effects of oriental medicine therapy on a patient of metrorrhagia and metrostaxis with endometrial polyp. Methods : The clinical data was analyzed on a patient of metrorrhagia and metrostaxis with endometrial polyp whose main symptoms were dysfunctional uterine bleeding. A 27-year-old female who had been treated hormone replacement therapy for dysfunctional uterine bleeding at a obstetrics and gynecology became worse, so refused any more hormone replacement therapy and visited Dongsin university oriental hospital. The patient was admitted to the obstetrics and gynecology department of Dongsin university Oriental Medical Hospital, on Febrary 23, 2004 and remained until Apri 11, 2005. we treated the patient with a herb-medication, acupunture therapy, moxa therapy and etc. Results : After treatment, improvement was seen in dysfunctional uterine bleeding, generalized weakness. Conclusion : The study suggests that oriental medicine therapy is significantly effective in the treatment of metrorrhagia and metrostaxis with endometrial polyp.

• Journal of the Korean Society of Radiology
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• v.84 no.3
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• pp.606-614
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• 2023

Purpose This study aimed to evaluate the efficacy and safety of transcatheter arterial embolization (TAE) for bleeding due to uterine body cancer. Materials and Methods In this retrospective study, six patients with varying types of uterine body cancer who underwent TAE for bleeding control were investigated. Angiographic findings, cross-sectional images, TAE details, and clinical outcomes were studied. Technical and clinical success rates were calculated. Results The identified patients had endometrioid adenocarcinoma, sarcoma, and gestational trophoblastic neoplasia, and most were patients with advanced-stage cancer. In four patients, tumor bleeding presented as vaginal bleeding. Technical success was achieved in all seven TAE procedures in six patients. Two patients with recurrent masses who had undergone hysterectomy presented with hematochezia, and TAE was able to provide technical success in these patients as well. The clinical success rate was 50%, indicating bleeding control for > 1 week. Rebleeding was directly associated with death in one patient. On the following day, mild fever was observed in one patient. Conclusion TAE can be considered an effective and safe method of bleeding control for uterine body cancer, especially during critical periods throughout the disease course of patients with inoperable, advanced-stage cancer.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.12
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• pp.4971-4975
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• 2015

Background: Several methods have been presented for the evaluation of the endometrium in patients with abnormal uterine bleeding, which include minimal invasive and invasive approaches such as diagnostic curettage or endometrial biopsy by Pipelle. Many studies have been performed in order to compare two methods; diagnostic curettage and outpatient endometrial biopsy. This investigation compared sampling adequacy, endometrial histopathology, failure rates, duration and costs between diagnostic curettage in a hospital and endometrial biopsy. Materials and Methods: This single blind clinical trial was performed on 130 patients older than 35 years who was referred to Amir training hospital in 2013 for elective diagnostic curettage because of abnormal uterine bleeding. For all patients eligible for the study, an endometrial sample by Pipelle was taken without anesthesia or dilatation. Then under general anesthesia diagnostic curettage was performed by sharp curette. Sampling duration was calculated and both samples were sent to the same pathologist. The diagnostic values of two methods in the diagnosis of normal endometrium, endometrial hyperplasia and carcinoma were compared. The costs of these two methods were also compared. Data analysis was performed by SPSS (version 16.0) software. Chi-Square, Fisher, and Pearson tests were used and were considered statistically significant at P values less than 0.05. Results: Two methods were agreed upon 88% of sampling adequacy and 94% of pathological results. Specificity of 100% and sensitivity of 90% for detection of proliferative endometrium, secretory endometrium, simple hyperplasia without atypia and 100% for cancer were recorded. Pipelle diagnostic accuracy in comparison with curettage, have been reported over 97%, so the failure rate in this study was below 5%. Sensitivity of Pipelle for detection of atrophic endometrium was reported below 50%. Duration and cost was lower in Pipelle versus curettage. Conclusions: It is concluded that due to high agreement and cohesion coefficient between curettage and Pipelle on the issue of sampling adequacy, histopathology finding (except atrophic endometrium), low failure rate, duration of sampling and cost, Pipelle can be introduced as a suitable alternative of diagnostic curettage.

• The Korean Journal of Cytopathology
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• v.13 no.1
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• pp.1-7
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• 2002

The significance of endometrial cells on cervicovaginal smears is underestimated. The aim of this study is to evaluate the detection rate of endometrial cells on cervicovaginal smears. The materials consisted of two groups. Group I was 701 cervicovaginal smears from patients with no gynecological problems. Group II was 208 cervicovaginal smears from patients with abnormal uterine bleeding followed by endometrial curettage; 31 cases of endometrial adenocarclnoma(CA), 19 cases of endometrial hyperplasia(HP), 83 cases of dysfunctional uterine bleeding(DUB), and 75 cases of normal endometrium. Cervicovaginal smears were reviewed according to the criteria of The Bethesda System. Endometrial cells were identified in 15 of 701 cases(2.1%) in group I and 64 of 208 cases(30.8%) in group II. Among group II, detection rate of endometrial cells was the highest in CA (51.6%) compared to HP(26.3%), DUB(41.0%), and normal endometrium(12.0%) (p<0.05). Cytologic atypia of endometrial cells was not found In group I, but was more frequently identified in CA(87.5%) than in HP(10.5%) or DUB(14.7%) (p<0.05). Exfollatlon of endometrial cells might be related to abnormal endometrial lesion, and reporting of endometrial cells in the cervicovaginal smear may increase a chance to detect endometrial lesions especially in patients with abnormal uterine bleeding.

• The Journal of Korean Obstetrics and Gynecology
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• v.31 no.4
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• pp.110-127
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• 2018

Objectives: To evaluate the effectiveness and safety of traditional herbal medicine (THM) in the treatment of dysfunctional uterine bleeding (DUB) versus conventional western medicine. Methods: Randomized Controlled Trials (RCTs) comparing THM vs. conventional western medicine for DUB, were obtained from PubMed, Cochrane Library, Embase, CNKI, RISS, NDSL, KISS and OASIS. The risk of bias was assessed by using Cochrane's risk of bias tool. Results: 16 RCTs with 1,659 patients were identified and reviewed. 10 RCTs reported THM was statistically effective than control group in effective rate. Also recurrent rate was estimated in 6 RCTs and was lower than control group. 7 studies observed adverse events (AEs) and severe AEs were not reported. Conclusions: Despite several limitations, this review suggested that THM was safe and effective in the treatment of DUB. THM may also decrease the recurrence rate. However, this could not be proven conclusively. To ensure evidence-based clinical practice, more sternly designed trials are warranted.