• 웰빙융합연구
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• 제6권3호
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• pp.25-32
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• 2023

Purpose: This study is to improve awareness of MSDS in order to prevent university accidents and protect university laboratory workers. In order to improve awareness, measures to increase accessibility through auxiliary means (warning signs, One Page Sheet MSDS, etc) and ways to strengthen safety training (improvement and strengthen MSDS training). Research design, data and methodology: A questionnaire survey was adopted as a research method for this study. Question items were selected, modified, and supplemented by referring to the previous paper. Results: As a result of the survey, MSDS found that it was difficult to find the information they wanted and that there were many technical terms and limitations in using it. In addition, MSDS training is underway, but few university laboratory workers felt that training was helping. This shows that the effectiveness of training is virtually insignificant. Therefore, it seems that improvement measures are needed to solve this. Conclusions: One Sheet MSDS, an effective way for university laboratory workers to communicate information, and MSDS information should be provided with warning signs with large phrases and good visibility. In addition, this study proposes a One Sheet MSDS that prioritizes important MSDS items over all items in the MSDS, and in the field of education, several improvements are proposed, such as "To prevent problems and answers from being shared on the Internet" and "To improve the difficulty of checking the online curriculum".

• Asian-Australasian Journal of Animal Sciences
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• 제29권6호
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• pp.855-864
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• 2016

The objective of this study was to compare the physicochemical and nutritional properties of breast and thigh meat from commercial Chinese crossbred chickens (817 Crossbred chicken, 817C), imported commercial broilers (Arbor Acres broiler, AAB), and commercial spent hens (Hyline Brown, HLB). The crossbred chickens, commercial broilers and spent hens were slaughtered at their typical market ages of 45 d, 40 d, and 560 d, respectively. The results revealed that several different characteristic features for the three breeds. The meat of the 817C was darker than that of the other two genotypes. The 817C were also characterized by higher protein, lower intramuscular fat, and better texture attributes (cooking loss, pressing loss and Warner-Bratzler shear force [WBSF]) compared with AAB and HLB. The meat of the spent hens (i.e. HLB) was higher in WBSF and total collagen content than meat of the crossbred chickens and imported broilers. Furthermore, correlation analysis and principal component analysis revealed that there was a clear relationship among physicochemical properties of chicken meats. With regard to nutritional properties, it was found that 817C and HLB exhibited higher contents of essential amino acids and essential/non-essential amino acid ratios. In addition, 817C were noted to have highest content of microelements whereas AAB have highest content of potassium. Besides, 817C birds had particularly higher proportions of desirable fatty acids, essential fatty acids, polyunsaturated/saturated and (18:0+18:1)/16:0 ratios. The present study also revealed that there were significant differences on breast meat and thigh meat for the physicochemical and nutritional properties, regardless of chicken breeds. In conclusion, meat of crossbred chickens has some unique features and exhibited more advantages over commercial broilers and spent hens. Therefore, the current investigation would provide valuable information for the chicken meat product processing, and influence the consumption of different chicken meat.

• 한국산업보건학회지
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• 제31권4호
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• pp.396-416
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• 2021

Objectives: This study was conducted to analyze the trends of government R&D (R&D) projects related to laboratory safety over the past 20 years. Methods: We collected publications from various databases(DBs) with words such as laboratory(ies), lab(s), researcher(s), laboratory worker(s), safety, environment, hazard(s), risk(s), and so on. Selected publications were analyzed by the research funds and the number of projects according to the investment subject and research characteristics. Results: About 93% of the total R&D budget went to government policy projects, not scientific research. Second, from the perspective of 'safety management activities', most of the research is related to management and inspection at the organizational level. Issues that need to be discussed at the national level like policy governance are not included. Third, focusing on the 'safety management cycle', there were few studies related to 'prediction' or 'post-response'. Fourth, when an analysis framework combining the perspectives of 'safety management activities' and 'safety management cycle' is applied, most of the budget is spent on infrastructure such as digital management systems, whereas basic knowledge for prevention and production of evidence was very few. Conclusions: In order to prevent policy planning without policy evaluation, implementation without strategy, and evaluation without evidence, it is necessary to expand investment in empirical research on risks, research on the effectiveness of current application methods, and research on theory development. The government budget for laboratory safety-related projects should be managed separately from the R&D budget for scientific research. Although less than 5% of the budget allocated to scientific research is the total budget, an optical illusion occurs because both the project budget and the scientific research budget are counted as R&D budgets.

• Journal of Ginseng Research
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• 제44권4호
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• pp.580-592
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• 2020

Background: Radix et Rhizoma Ginseng (thereafter called ginseng) has been used as a medicinal herb for thousands of years to maintain people's physical vitality and is also a non-organ-specific cancer preventive and therapeutic traditional medicine in several epidemiologic and preclinical studies. Owing to few toxic side effects and strong enhancement on body immunity, ginseng has admirable application potential and value in cancer chemoprevention. The study aims at investigating the chemopreventive effects of ginseng on cutaneous carcinoma and the underlying mechanisms. Methods: The mouse skin cancer model was induced by 7,12-dimethylbenz[a]anthracene/12-O-tetradecanoylphorbol-13-acetate. Ultraperformance liquid chromatography/mass spectrometry was used for identifying various ginsenosides, the main active ingredients of ginseng. Comprehensive approaches (including network pharmacology, bioinformatics, and experimental verification) were used to explore the potential targets of ginseng. Results: Ginseng treatment inhibited cutaneous carcinoma in terms of initiation and promotion. The content of Rb1, Rb2, Rc, and Rd ginsenosides was the highest in both mouse blood and skin tissues. Ginseng and its active components well maintained the redox homeostasis and modulated the immune response in the model. Specifically, ginseng treatment inhibited the initiation of skin cancer by enhancing T-cell-mediated immune response through upregulating HSP27 expression and inhibited the promotion of skin cancer by maintaining cellular redox homeostasis through promoting nuclear translocation of Nrf2. Conclusion: According to the study results, ginseng can be potentially used for cutaneous carcinoma as a chemopreventive agent by enhancing cell-mediated immunity and maintaining redox homeostasis with multiple components, targets, and links.

• Wind and Structures
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• 제27권4호
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• pp.255-267
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• 2018

This paper investigated the wind-snow flow around the bogie region of a high-speed train under crosswinds using a coupled numerical method of the unsteady Realizable $k-{\varepsilon}$ turbulence model and discrete phase model (DPM). The flow features around the bogie region were discussed and the influence of bogie fairing height on the snow accumulation on the bogie was also analyzed. Here the high-speed train was running at a speed of 200 km/h in a natural environment with the crosswind speed of 15 m/s. The mesh resolution and methodology for CFD analysis were validated against wind tunnel experiments. The results show that large negative pressure occurs locally on the bottom of wheels, electric motors, gear covers, while the positive pressure occurs locally on those windward surfaces. The airflow travels through the complex bogie and flows towards the rear bogie plate, causing a backflow in the upper space of the bogie region. The snow particles mainly accumulate on the wheels, electric motors, windward sides of gear covers, side fairings and back plate of the bogie. Longer side fairings increase the snow accumulation on the bogie, especially on the back plate, side fairings and brake clamps. However, the fairing height shows little impact on snow accumulation on the upper region of the bogie. Compared to short side fairings, a full length side fairing model contributes to more than two times of snow accumulation on the brake clamps, and more than 20% on the whole bogie.

• Wind and Structures
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• 제30권4호
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• pp.325-338
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• 2020

In this paper, the improvement of the anti-snow performance of a high-speed train (HST) is studied using the unsteady Reynolds-Averaged Navier-Stokes simulations (URANS) coupled with the Discrete Phase Model (DPM). The influences of the proposed flow control scheme on the velocity distribution of the airflow and snow particles, snow concentration level and accumulated mass in the bogie cavities are analyzed. The results show that the front anti-snow structures can effectively deflect downward the airflow and snow particles at the entrance of the cavities and alleviate the strong impact on the bogie bottom, thereby decrease the local accumulated snow. The rotational rear plates with the deflecting angle of 45° are found to present well deflecting effect on the particles' trajectories and force more snow to flow out of the cavities, and thus significantly reduce the accretion distribution on the bogie top. Furthermore, running speeds of HST are shown to have a great effect on the snow-resistance capability of the flow control scheme. The proposed flow control scheme achieves more snow reduction for HST at higher train's running speed in the cold regions.

• Nuclear Engineering and Technology
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• 제55권1호
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• pp.310-323
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• 2023

The k-eigenvalue neutronics/thermal-hydraulics coupling calculation is a key issue for reactor design and analysis. Jacobian-free Newton-Krylov (JFNK) method, featured with super-linear convergence rate and high efficiency, has been attracting more and more attention to solve the multi-physics coupling problem. However, it may converge to the high-order eigenmode because of the multiple solutions nature of the k-eigenvalue form of multi-physics coupling issue. Based on our previous work, a modified JFNK with a line search method is proposed in this work, which can find the fundamental eigenmode together with thermal-hydraulics feedback in a wide range of initial values. In detail, the existing modified JFNK method is combined with the line search strategy, so that the intermediate iterative solution can avoid a sudden divergence and be adjusted into a convergence basin smoothly. Two simplified 2-D homogeneous reactor models, a PWR model, and an HTR model, are utilized to evaluate the performance of the newly proposed JFNK method. The results show that the performance of this proposed JFNK is more robust than the existing JFNK-based methods.

• Nuclear Engineering and Technology
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• 제55권4호
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• pp.1350-1364
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• 2023

2D/1D coupling method is an important neutron transport calculation method due to its high accuracy and relatively low computation cost. However, 2D/1D coupling method may diverge especially in small axial mesh size. To analyze the convergence behavior of 2D/1D coupling method, a Fourier analysis for k-eigenvalue neutron transport problems is implemented. The analysis results present the divergence problem of 2D/1D coupling method in small axial mesh size. Several common attempts are made to solve the divergence problem, which are to increase the number of inner iterations of the 2D or 1D calculation, and two times 1D calculations per outer iteration. However, these attempts only could improve the convergence rate but cannot deal with the divergence problem of 2D/1D coupling method thoroughly. Moreover, the choice of axial solvers, such as DGFEM SN and traditional SN, and its effect on the convergence behavior are also discussed. The results show that the choice of axial solver is a key point for the convergence of 2D/1D method. The DGFEM SN based 2D/1D method could converge within a wide range of optical thickness region, which is superior to that of traditional SN method.

• Nuclear Engineering and Technology
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• 제56권1호
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• pp.147-159
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• 2024

Plutonium-238 has always been considered as the one of the promising radioisotopes for space nuclear power supply, which has long half-life, low radiation protection level, high power density, and stable fuel form at high temperatures. The industrial-scale production of ²³⁸Pu mainly depends on irradiating solid ²³⁷NpO₂ target in high flux reactors, however the production process faces problems such as large fission loss and high requirements for product quality control. In this paper, a conceptual design study of producing ²³⁸Pu in a multi-purpose high flux reactor was evaluated and analyzed, which includes a sensitivity analysis on ²³⁸Pu production and a further study on the irradiation scheme. It demonstrated that the target structure and its location in the reactor, as well as the operation scheme has an impact on ²³⁸Pu amount and product quality. Furthermore, the production efficiency could be improved by optimizing target material concentration, target locations in the core and reflector. This work provides technical support for irradiation production of ²³⁸Pu in high flux reactors.

• Food Science and Biotechnology
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• 제18권3호
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• pp.579-585
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• 2009

Solid-phase microextraction (SPME) has gained widespread acceptance in sample pretreatment due to its solvent-free and easy-to-operate properties. SPME fibers are considered as a key part of SPME technique, since it primarily determines the extraction performance of the method including sensitivity, selectivity, and reproducibility. Generally speaking, target analyte with different chemical property requires fiber coating that has the best affinity towards it. Due to the lack of varieties of commercial fibers available currently, considerable efforts have been recently made to develop tailor-made fibers to fulfill increasing demands of different analysis. This paper concisely classify some SPME fiber preparation approaches such as sol-gel technology, physical deposition, molecularly imprinted technique, and their respective application in food safety analysis.