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Research Progress of the Structure Vibration-Attitude Coordinated Control of Spacecraft

  • Yang, Jingyu;Qu, Shiying;Lin, Jiahui;Liu, Zhiqi;Cui, Xuanming;Wang, Chu;Zhang, Dujiang;gu, Mingcheng;Sun, Zhongrui;Yang, Kang;Zhou, Lanwei;Chen, Guoping
    • International Journal of Aeronautical and Space Sciences
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    • v.16 no.4
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    • pp.590-601
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    • 2015
  • This paper gives an overview of research on the field of structure vibration-attitude coordinated control of spacecraft. First of all, the importance of the technology has been given an introduction, and then later the research progress of space structure dynamics modeling, research progress of structure vibration-attitude coordinated control of flexible spacecraft have been discussed respectively. Finally, future research on application of structure vibration-attitude coordinated control of spacecraft has been recommended.

Potential Applicability of Local Resection With Prophylactic Left Gastric Artery Basin Dissection for Early-Stage Gastric Cancer in the Upper Third of the Stomach

  • Akashi, Yoshimasa;Ogawa, Koichi;Hisakura, Katsuji;Enomoto, Tsuyoshi;Ohara, Yusuke;Owada, Yohei;Hashimoto, Shinji;Takahashi, Kazuhiro;Shimomura, Osamu;Doi, Manami;Miyazaki, Yoshihiro;Furuya, Kinji;Moue, Shoko;Oda, Tatsuya
    • Journal of Gastric Cancer
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    • v.22 no.3
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    • pp.184-196
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    • 2022
  • Purpose: Total or proximal gastrectomy of the upper-third early gastric cancer (u-EGC) often causes severe post-gastrectomy syndrome, suggesting that these procedures are extremely invasive for patients without pathologically positive lymph node (LN) metastasis. This study aimed to evaluate the clinical applicability of a stomach function-preserving surgery, local resection (LR), with prophylactic left gastric artery (LGA)-basin dissection (LGA-BD). Materials and Methods: The data of patients with u-EGC (pathologically diagnosed as T1) were retrospectively analyzed. Total gastrectomy was performed in 30 patients, proximal gastrectomy in 45, and subtotal gastrectomy in 6; the LN status was evaluated assuming that the patients had already underwent LR + LGA-BD. This procedure was considered feasible in patients without LN metastases or in patients with cancer in the LGA basin. The reproducibility of the results was also evaluated using an external validation dataset. Results: Of the 82 eligible patients, 79 (96.3%) were cured after undergoing LR + LGA-BD, 74 (90.2%) were pathologically negative for LN metastases, and 5 (6.1%) had LN metastases, but these findings were only observed in the LGA basin. Similarly, of the 406 eligible tumors in the validation dataset, 396 (97.5%) were potentially curative. Tumors in the lesser curvature, post-endoscopic resection status, and small tumors (<20 mm) were considered to be stronger indicators of LR + LGA-BD as all subpopulation cases met our feasibility criteria. Conclusions: More than 95% of the patients with u-EGC might be eligible for LR + LGA-BD. This function-preserving procedure may contribute to the development of u-EGC without pathological LN metastases, especially for tumors located at the lesser curvature.

Roles of the Faculty and Librarian in the Collaborative Relationships at Vietnamese Universities: A Qualitative Methodology

  • Nguyen, Lan Thi;Tuamsuk, Kulthida
    • Journal of Information Science Theory and Practice
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    • v.8 no.1
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    • pp.33-44
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    • 2020
  • This article is a part of a doctoral research project on developing the faculty-librarian collaboration model to support learning and research at Vietnamese universities. The findings of this study have crucial significance in drawing a broader view of the importance of faculty-librarian collaboration and the roles of such collaborators at Vietnamese universities. Qualitative methodology was used to formulate related topics and achieve these research objectives. Semi-structured interviews were carried out at four universities in Vietnam with three key informants, including the faculty, librarian, and administrators (dean/vice dean of faculty, director/deputy director of the library). From March to April 2019, researchers conducted 29 interviews with three participant groups. The striking results of this research showed that the faculty and librarians realized the significance of a collaborative relationship and expect that Vietnamese universities will design and deploy a model to boost the effectiveness of this collaboration. Besides this, the study found that the collaborators play certain important roles within the collaborative relationship, for instance, that of reference, coordinator, special lecturer, cooperator, and information user.

Bufalin, a Traditional Oriental Medicine, Induces Apoptosis in Human Cancer Cells

  • Takai, Noriyuki;Kira, Naoko;Ishii, Terukazu;Yoshida, Toshie;Nishida, Masakazu;Nishida, Yoshihiro;Nasu, Kaei;Narahara, Hisashi
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.1
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    • pp.399-402
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    • 2012
  • Bufalin is a traditional oriental medicines which induces apoptosis in some lines of human tumor cells. It constitutes the major digoxin-like immunoreactive component of Chan Su, obtained from the skin and parotid venom glands of toads. Bufalin is cardioactive C-24 steroids that exhibits a variety of biological activities, such as cardiotonic, anaesthetic, blood pressure stimulatory, respiratory and antineoplastic effects. In terms of its anti-tumor activity, bufalin has been demonstrated to inhibit the growth of tumors, such as endometrial and ovarian cancers. This commentary introduces biologic and therapeutic effects of bufalin in treating some cancers. The compound is able to mediate inhibition of cell growth, cell cycle arrest, apoptosis, and expression of genes related to the malignant phenotype in human cancer cells.

Dickkopf-1 Levels in Turkish Patients with Bladder Cancer and its Association with Clinicopathological Features

  • Kaba, Mehmet;Pirincci, Necip;Benli, Erdal;Gecit, Ilhan;Gunes, Mustafa;Yuksel, Mehmet Bilgehan;Tok, Adem;Kemik, Ahu Sarbay
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.1
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    • pp.381-384
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    • 2014
  • Background: Evidence indicates that Dickkopf-1 (DKK-1) levels may be a biomarker for cancer risk. The aim of this study was to assess DKK-1 and its correlation with clinic-pathological features in patients with bladder cancer. Materials and Methods: DKK-1 levels were determined in serum samples from 90 patients with bladder cancer before transurethral tumor resection. The concentrations of DKK-1 were determined by using enzyme linked immune-sorbent assay (ELISA). Results: Elevated preoperative DKK-1 levels were associated with tumor stage (p<0.001), grade (p<0.001) and histological grade (p<0.001). Conclusions: The results of our study demonstrated that the level of serum DKK-1 is correlated with both disease progression and increase in the tumor grade. Preoperative serum DKK-1 elevation may thus represent a novel marker for the determination of bladder cancer and the detection of patients with a likely poor clinical outcome.

Serum Levels of Trace Elements in Patients with Prostate Cancer

  • Kaba, Mehmet;Pirincci, Necip;Yuksel, Mehmet Bilgehan;Gecit, Ilhan;Gunes, Mustafa;Ozveren, Huseyin;Eren, Huseyin;Demir, Halit
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.6
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    • pp.2625-2629
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    • 2014
  • Background: Trace elements are major components of biological structures; however, excessive levels of these elements can be toxic. Materials and Methods: In the present study, serum levels of trace elements were measured in 30 patients with newly diagnosed as prostate cancer and 32 healthy volunteer by using furnace atomic absorption spectrophotometry. Results: It was found that there was an increase in serum levels of Co, Cu, Mg and Pb (p<0.05), whereas a decrease in serum levels of Fe, Mn, and Zn levels in patients with prostate cancer (p<0.05). Conclusions: These changes may be important in the pathogenesis of prostate cancers; however, further prospective studies are needed to identify relationships between prostate cancer and trace elements.

Synthesis, Characterization and Antimicrobial Activity of Garcinol Capped Silver Nanoparticles

  • Fernando, H.N.;Kumarasinghe, K.G.U.R.;Gunasekara, T.D.C.P.;Wijekoon, H.P.S.K.;Ekanayaka, E.M.A.K.;Rajapaksha, S.P.;Fernando, S.S.N.;Jayaweera, P.M.
    • Journal of Microbiology and Biotechnology
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    • v.29 no.11
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    • pp.1841-1851
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    • 2019
  • Garcinol, a well-known medicinal phytochemical, was extracted and isolated from the dried fruit rinds of Garcinia quaesita Pierre. In this study, garcinol has successfully used to reduce silver ions to silver in order to synthesize garcinol-capped silver nanoparticles (G-AgNPs). The formation and the structure of G-AgNPs were confirmed by UV-visible spectroscopy, transmission electron microscopy and Fourier transform infrared spectroscopy. The antimicrobial activity of garcinol and G-AgNPs were investigated by well diffusion assays, broth micro-dilution assays and time-kill kinetics studies against five microbial species, including Staphylococcus aureus (ATCC 25923), Pseudomonas aeruginosa (ATCC 27853), Escherichia coli (ATCC 25922), Candida albicans (ATCC 10231) and clinically isolated methicillin-resistant Staphylococcus aureus (MRSA). The formation of G-AgNPs is a promising novel approach to enhancing the biological activeness of silver nanoparticles, and to increase the water solubility of garcinol which creates a broad range of therapeutic applications.

Comparison of chlorpyrifos resistance in Culex pipiens pipiens (Diptera: Culicidae) collected from Northern and Southern Tunisia

  • DAABOUB, Jabeur;TABBABI, Ahmed;BEN CHEIKH, Raja;LAAMARI, Ali;FERIANI, Mohamed;BOUBAKER, Chokri;BEN JHA, Ibtissem;BEN CHEIKH, Hassen
    • Entomological Research
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    • v.48 no.5
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    • pp.400-404
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    • 2018
  • In this study, we investigated resistance to the organophosphates chlorpyrifos in Tunisian populations of Culex pipiens pipiens. Three field populations were collected from Northern and central Tunisia between 2003 and 2005 and used for the bioassays tests. Our results registered moderate and high levels of resistance to chlorpyrifos which ranged from 33.8 to 111. The chlorpyrifos resistant populations were highly resistant to propoxur indicated an insensitive acetylcholinesterase 1 (AChE 1). The highest frequency of AChE 1 resistant phenotypes (64%) was recorded in the most resistant population (sample # 1). Bioassays conducted in the presence of synergists showed that not esterases were involved as the resistance mechanism to chlorpyrifos. However, CYP450 was partly involved in the resistance of the most resistant sample (# 1). Starch electrophoresis showed that three esterases were present in studied samples: A2-B2, A4-B4 and B12. Results are discussed in relation to the selection pressure caused by insecticide treatments.