• Title/Summary/Keyword: universal class

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A Study of SMART Class Observation Based on 'Universal Design for Learning(UDL)' ('보편적 학습 설계(UDL)'에 기반한 SMART 수업관찰 연구)

  • Jeon, Young-Joo
    • Proceedings of the Korea Contents Association Conference
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    • 2014.11a
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    • pp.113-114
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    • 2014
  • 미국 등 유럽에서는 UDL이 유치원에서부터 대학 교육까지의 모든 과목에 소개되어 모든 학습자가 소외됨 없이 수업에 참여하고, 학습효과를 얻고 있는 실정에 비하여 우리나라는 아직 UDL의 개념조차 교과교육계에 소개되어 있지 않고 있다. 이에 UDL을 통해 최근 교육계의 최대 이슈인 스마트 교육의 이론적 기반을 다지고, 더 나아가 UDL을 통해서 본 스마트 수업관찰 도구를 개발함을 본 연구의 목적으로 한다.

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On Frequentist Properties of Some Hierachical Bayes Predictors for Small Domain Data in Repeated Surveys

  • Narinder K. Nangia;Kim, Dal-Ho
    • Journal of the Korean Statistical Society
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    • v.26 no.2
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    • pp.245-259
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    • 1997
  • The paper shows that certain hierachical Bayes (HB) predictors for small domain data in repeated surveys "universally" or "stochastically" dominate all linear unbiased predictors. Also, the HB predictors are "best" within the class of all equivariant predictors under a certain group of transformations.tain group of transformations.

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Robust Adaptive Controller for MIMO Nonsquare Nonlinear Systems Using Universal Function Approximators

  • Park, Jang-Hyun;Seo, Ho-Joon;Park, Gwi-Tae
    • 제어로봇시스템학회:학술대회논문집
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    • 2001.10a
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    • pp.40.4-40
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    • 2001
  • This paper addresses the problem of designing robust adaptive output tracking control for a class of MIMO nonlinear systems which have different number of inputs and outputs The stability of the whole closed-loop system is guaranteed in the sense of Lyapunov and uniformly Itimately boundedness of the tracking error vector as well as estimated parameters are shown. In addition, we show that the restrictive assumptions on input gain matrix which is presumed in the past works can be eliminated by using proposed control law.

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The Study on Ending Repetition Construction ("-고 자시고"류 어미 반복 구성에 관한 연구)

  • Cho, Mihee
    • Korean Linguistics
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    • v.76
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    • pp.213-241
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    • 2017
  • Korean verb 'Casi-', which is treated as negative element in dictionaries, is actually a placeholder shows indefinite use, and '-ko casiko' construction is understood as a member of a class of 'Ending repetition construction'. However, unlike among others, '-ko casiko' construction is now undergoing developement of its negative polarity. Because of its indefiniteness, '-ko casiko' construction change its meaning into a universal negative when it is used in negative sentences.

Comparing the Benefits and Drawbacks of Stem Cell Therapy Based on the Cell Origin or Manipulation Process: Addressing Immunogenicity

  • Sung-Ho Chang;Chung Gyu Park
    • IMMUNE NETWORK
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    • v.23 no.6
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    • pp.44.1-44.16
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    • 2023
  • Mesenchymal stem cells (MSCs) are effective in treating autoimmune diseases and managing various conditions, such as engraftment of allogeneic islets. Additionally, autologous and HLA-matched allogeneic MSCs can aid in the engraftment of human allogeneic kidneys with or without low doses of tacrolimus, respectively. However, HLA alloantigens are problematic because cell therapy uses more HLA-mismatched allogeneic cells than autologous for convenience and standardization. In particular, HLA-mismatched MSCs showed increased Ag-specific T/B cells and reduced viability faster than HLA-matched MSCs. In CRISPR/Cas9-based cell therapy, Cas9 induce T cell activation in the recipient's immune system. Interestingly, despite their immunogenicity being limited to the cells with foreign Ags, the accumulation of HLA alloantigen-sensitized T/B cells may lead to allograft rejection, suggesting that alloantigens may have a greater scope of adverse effects than foreign Ags. To avoid alloantigen recognition, the β2-microglobulin knockout (B2MKO) system, eliminating class-I MHC, was able to avoid rejection by alloreactive CD8 T cells compared to controls. Moreover, universal donor cells in which both B2M and Class II MHC transactivator (CIITA) were knocked out was more effective in avoiding immune rejection than single KO. However, B2MKO and CIITA KO system remain to be controlled and validated for adverse effects such as the development of tumorigenicity due to deficient Ag recognition by CD8 T and CD4 T cells, respectively. Overall, better HLA-matching or depletion of HLA alloantigens prior to cell therapy can reduce repetitive transplantation through the long-term survival of allogeneic cell therapy, which may be especially important for patients seeking allogeneic transplantation.

An Analytical Study on Space Configuration in After-School Care Class for Elementary School - Focused on Guidelines of Emementary School Care Classes - (초등돌봄교실 공간구성특징에 관한 분석연구 - 초등 돌봄교실 길라잡이를 중심으로 -)

  • Kim, Sora
    • Journal of the Korean Institute of Educational Facilities
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    • v.28 no.6
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    • pp.3-13
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    • 2021
  • Introduced in 2004 as an 'After-School Academy' policy, the 'After-School Care Class' has become a universal program for elementary schools over time. While the concept of public education service has expanded and changed in various ways including educational welfare, the physical environment of the care classroom has undergone fixed changes within the uniform classroom structure of a standardized school space. The purpose of this study is to identify spatial characteristics of care classroom through chasing and analysing changes in the care class space configuration from 2004 to the present. The findings are as follows. The plan of the early care classroom wasn't much different from the existing common classroom, and it was only in 2007 that the kitchen and floor heating appeared for the first time.From the 2015 standard plan, prominent differentiation of the space between learning activities and resting area was shown, but the spatial characteristics are nothing more than a division that utilizes ready-made furniture. A distinctive feature of the 2018 Seoul care classes are diversity. In the case of the care exclusive classrooms, the division between the support space and the main activity space became more clear using furniture integrated open walls and various floor levels. In the case of a shift classrooms that is used together with common classrooms, it is characterized by flexibility that allows dramatically different classroom configurations for each time period by using a convertible furnishing space.

Estimation of remodeling of small-scale houses to improve the residential environment for the underprivileged - case study on the TV program 'Love House' for free residential remodeling - (소외계층의 주거환경개선을 위한 소규모 주택 리모델링에 관한 평가연구 - TV 방송 무료주택 리모델링 프로그램 '러브하우스' 사례조사를 중심으로-)

  • Yang, Se-Eun
    • Korean Institute of Interior Design Journal
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    • v.17 no.3
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    • pp.34-42
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    • 2008
  • The objective of this research is not only making the planning guides regarding a small-scale residential remodeling but also examining closely the social roles of the interior design for the poor and the underprivileged class by analyzing the residential remodeling cases. The scope of research includes 40 remodeling houses free of charge which are broadcasted in the TV program 'Love House'. Taking in consideration the characteristics of users like parentless or single-parent families and families with disabled persons, this study uses the spatial approach, user's convenience approach and psychological problem solving approach, in terms of the methodology. In result of the analysis of their interior design, first of all, it is essential solving the problem of limited house space by comparison with the family number. Second, the universal design concept for the family with disabled persons(72.5%), old persons or children is strengthened guaranteeing privacy in small and old interior space. Third, the interior design is focused in increasing communication among family members, because mental and physical obstacle would obstruct accessibility among them. This research shows the importance of the interior design which makes wide social roles contributing to create "welfare society".

Influenza Virus-Derived CD8 T Cell Epitopes: Implications for the Development of Universal Influenza Vaccines

  • Sang-Hyun Kim;Erica Espano;Bill Thaddeus Padasas;Ju-Ho Son;Jihee Oh;Richard J. Webby;Young-Ran Lee;Chan-Su Park;Jeong-Ki Kim
    • IMMUNE NETWORK
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    • v.24 no.3
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    • pp.19.1-19.15
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    • 2024
  • The influenza virus poses a global health burden. Currently, an annual vaccine is used to reduce influenza virus-associated morbidity and mortality. Most influenza vaccines have been developed to elicit neutralizing Abs against influenza virus. These Abs primarily target immunodominant epitopes derived from hemagglutinin (HA) or neuraminidase (NA) of the influenza virus incorporated in vaccines. However, HA and NA are highly variable proteins that are prone to antigenic changes, which can reduce vaccine efficacy. Therefore, it is essential to develop universal vaccines that target immunodominant epitopes derived from conserved regions of the influenza virus, enabling cross-protection among different virus variants. The internal proteins of the influenza virus serve as ideal targets for universal vaccines. These internal proteins are presented by MHC class I molecules on Ag-presenting cells, such as dendritic cells, and recognized by CD8 T cells, which elicit CD8 T cell responses, reducing the likelihood of disease and influenza viral spread by inducing virus-infected cell apoptosis. In this review, we highlight the importance of CD8 T cell-mediated immunity against influenza viruses and that of viral epitopes for developing CD8 T cell-based influenza vaccines.

A Study on the Tendency of Standardization Related to Universal Design (유니버설 디자인 관련 표준화 동향에 관한 연구)

  • Lee, Ho-Soong
    • Archives of design research
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    • v.18 no.1 s.59
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    • pp.175-184
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    • 2005
  • With the rapid progress of the aging society in Korea, the silver generation is emerging as another class of users in the new population structure. This is a social issue to be dealt with, and the effect of such a change is being observed dearly in the design area. In addition, there are increasing demands for consideration of minor groups of users including the elderly, the disabled, the left-handed, children and pregnant women and nursing mothers, who have been treated as the weak. Such a human-centered idea may be the manifestation of the recovery of humanity and the self-realization of human beings through experiences and reflections of the industrial society of the past. The present study examined the tendency of design standardization centering on universal design, which has emerged in response to user-centered social needs, and suggested general considerations for the necessity of introducing such standards. These days the meanings of standardization are not limited to quality, performance, safety and economic aspect. Standardization is required to consider the diversity and the welfare of human beings. In addition, one of the important functions of standardization is to provide designers with important clues and guidelines for designing. In reality, however, standardization has been rejected by the circle of design for the reason that it deters free creation, so research on the introduction of standardization has been at standstill. As ISO/IEC Guide71 was published in November 2001, based on which, the Korea Standards Association established KS A ISO/IEC Guide71 without changing its contents. In companies' manufacturing activities, the progress of standardization in connection to universal design is growing more important. However, usefulness and interchangeability for the absolute majority resulting from standardization are incomparable. Lastly, the realization of universal design requires human-centered design mind, based on users' experiences and needs, the characteristics of the human bodies and inconvenient elements rather than standards for the sake of standardization.

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The Microleakage in Class V Cavity Based on Different Kinds of Several Dentin Adhesive and Composite Resin (5급 와동에서 수종의 상아질 접착제와 복합레진의 종류에 따른 미세누출)

  • Choi, Yoo-Seok;Jeong, Soon-Jeong;Jeong, Moon-Jin;Ahn, Yong-Soon;Park, Seon-Nyeo;Lim, Do-Seon
    • Journal of dental hygiene science
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    • v.13 no.3
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    • pp.330-338
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    • 2013
  • In order to explore microleakage in class V cavity based on different kinds of several dentin adhesive and composite resin, 2 kinds of composite resin was restored and exposed after applying 4 kinds of dentin adhesives. Deposited in methylene blue solution for 4 hours and cut in parallel with tooth longitudinal axis. By observing dye penetration level of enamel and dentin margins of each restored resin following conclusion was obtained. 1. In composite resin Filtek Z350XT Universal (3M/ESPE Dental Products, USA) in enamel margin, Easy Bond (3M/ESPE Dental Products) showed the lowest microleakage and this leakage was represented to be high in the order of Single Bond 2 (3M/ESPE Dental Products), Scotchbond Multi-Purpose (3M/ESPE Dental Products) and Cearfil SE Bond (Kuraray Medical Inc., Japan). In case of Filtek Z350XT Flowable (3M/ESPE Dental Products), Scotchbond Multi-Purpose showed the lowest microleakage and this leakage was represented to be high in the order of Single Bond 2, Clearfil SE Bond and Easy Bond. 2. In case of Filtek Z350XT Universal in dentin margin, Easy Bond showed the lowest microleakage and this leakage was represented to be high in the order of Scotchbond Multi-Purpose, Single Bond 2 and Clearfil SE Bond. In case of Filtek Z350XT Flowable, Scotchbond Multi-Purpose and Single Bond showed the lowest microleakage and this leakage was represented to be high in the order of Clearfil SE Bond and Easy Bond. 3. In all the groups excepting S-U group (Single Bond 2+Filtek Z350XT Universal), enamel margin showed more higher microleakage than that of dentin margin. 4. There was a difference between enamel and dentin margin among each group but it was not significant statistically (p>0.05). When summarizing this result, it is considered that composite resin and dentin adhesive could be applied selectively and particularly in case of applying 1-step self-etching dentin adhesive, this method would be advantageous for manipulation convenience and shortening of operation time.