• 제목/요약/키워드: univariate analysis

검색결과 1,012건 처리시간 0.03초

Risk Factors of Postoperative Nosocomial Pneumonia in Stage I-IIIa Lung Cancer Patients

  • Wang, Zeng;Cai, Xin-Jun;Shi, Liang;Li, Fei-Yan;Lin, Neng-Ming
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권7호
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    • pp.3071-3074
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    • 2014
  • Background: To investigate the related risk factors of postoperative nosocomial pneumonia (POP) in patients withI-IIIa lung cancer. Methods: Medical records of 511 patients who underwent resection for lung cancer between January 2012 to December 2012 were retrospectively reviewed. Risk factors of postoperative pneumonia were identified and evaluated by univariate and multivariate analyses. Results: The incidence of postoperative pneumonia in these lung cancer patients was 2.9% (15 cases). Compared with 496 patients who had no pneumonia infection after operation, older age (>60), histopathological type of squamous cell carcinoma and longer surgery time (>3h) were significant risk factors by univariate analysis. Other potential risk factors such as alcohol consumption, history of smoking, hypersensitivity, hypertension, diabetes mellitus and so on were not showed such significance in this study. Further, the multivariate analysis revealed that old age (>60 years) (OR 5.813, p=0.018) and histopathological type of squamous cell carcinoma (OR 5.831, p<0.001) were also statistically significant independent risk factors for postoperative pneumonia. Conclusions: This study demonstrated that being old aged (>60 years) and having squamous cell carcinoma histopathological type might be important factors in determining the risk of postoperative pneumonia in lung cancer patients after surgery.

The Relationship between Ownership Control Disparity and Firm Value: Empirical Evidence from High-Technology Firms in Korea

  • KIM, Su-In;SHIN, Hyejeong
    • The Journal of Asian Finance, Economics and Business
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    • 제8권5호
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    • pp.749-759
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    • 2021
  • We investigate the relationship between ownership control disparity and future firm value in high-technology industries, and whether the effect of ownership control disparity on future firm value is differentiated when high-tech industry firms belong to chaebol groups. Using 11,848 firm-year observations of Korean firms listed on the stock market from 2006 to 2019, we employ univariate analysis and Heckman 2 stage analysis to test our hypotheses. We define high-technology industries as ICT industries based on the Korean Standard Industrial Classification. We measure future firm value using average Tobin's q for the next three years and ownership control disparity using the shareholding ratio of affiliated companies. Our univariate test results show that mean of Tobin's q is higher in ICT firms than non-ICT firms and firms largely owned by affiliates. In multivariate test, we find that the ICT firms with higher ownership control disparity are positively associated with future firm value. However, this association is lessened when firms belong to a chaebol group. Based on our findings, we suggest ownership control disparity has an additional positive effect on future firm in high-technology industries. The negative impact of chaebol groups on the association suggests the possibility of diversification discount in business group.

Bayesian 기법을 이용한 혼합 Gumbel 분포 매개변수 추정 및 강우빈도해석 기법 개발 (A Bayesian Approach to Gumbel Mixture Distribution for the Estimation of Parameter and its use to the Rainfall Frequency Analysis)

  • 최홍근;오랑치맥솜야;김용탁;권현한
    • 대한토목학회논문집
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    • 제38권2호
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    • pp.249-259
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    • 2018
  • 우리나라의 기후 지형적 특성에 따라 연강수량의 50% 이상이 여름철에 내린다. 이러한 짧은 기간에 집중적으로 내리는 강수량 조건하에 수공구조물을 설계할 경우 대부분 극치빈도분석을 활용한다. 특히 우리나라의 경우 Gumbel 분포를 활용한 극치빈도분석을 많이 이용한다. 하지만, 최근 이상기후로 인하여 전세계적으로 강수량의 특징이 급격히 변하고 있으며, 우리나라 연강수량 특징도 바뀌고 있다. 즉, 기존의 단일 분포형으로 재현이 가능했던 수문기상 자료들이 혼합분포형의 특징을 가지게 되었으며 이러한 변화를 고려할 수 있는 극치빈도분석 개발이 요구되고 있는 실정이다. 본 연구에서는 두 개 이상의 첨두를 가지는 형태의 극치강수량 자료에 대해서 기존의 단일 Gumbel 분포형 기반 극치빈도분석과 혼합 Gumbel 분포형 기반의 극치빈도분석 결과를 비교하였다. 확률분포의 매개변수 산정시 우도함수를 Bayesian 기법을 통해 산정하여 각 분포형의 Bayesian information criterion (BIC) 값을 비교하였다. 분석한 결과, 앞서 제안된 혼합 Gumbel 분포형은 하나의 첨두를 가지는 단일 Gumbel 분포형에서 반영되지 못한 꼬리(tail)부분의 이중첨두 부분의 거동을 효과적으로 모의하는 것을 확인할 수 있었다. 결과적으로 설계강수량을 추정할 때 보다 신뢰성있는 접근이 가능하였다. 이러한 점에서 우리나라 극치강우자료 분석시 기존 단일분포기반의 빈도해석기법에 대안으로 적용이 가능할 것으로 판단된다.

홍수사상 요소의 상관성을 고려한 홍수사상의 평가 (Evaluation of Flood Events Considering Correlation between Flood Event Attributes)

  • 이정호;유지영;김태웅
    • 대한토목학회논문집
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    • 제30권3B호
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    • pp.257-267
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    • 2010
  • 홍수사상은 크게 첨두홍수량, 홍수용적, 지속기간 등과 같은 서로 상관된 세 가지의 요소에 의해 특성화되어진다. 그러나 그동안 수공학적 계획이나 설계 등을 위한 홍수빈도 해석에서는 주로 첨두홍수량 한가지 요소에 초점을 맞추어 홍수빈도 해석을 수행해 왔다. 이러한 단변량 홍수빈도 해석은 서로 상관된 홍수사상 요소 사이의 복잡한 확률적 거동을 분석하는 데 있어 한계를 가지고 있다. 본 연구에서는 Gumbel 혼합모형, 이변량 감마분포, 이변량 핵밀도 함수 등 세 가지의 이변량 빈도해석 방법을 적용하여 이변량 빈도해석을 수행하고 그 결과를 단변량 빈도해석 방법의 결과와 비교 분석하였다. 소양강댐의 35개년 일 유입량 자료와 대청댐의 28개년 일 유입량 자료에 대해 각각의 홍수사상을 분리하고, 홍수사상 자료의 통계량과 매개변수, 최적 광역폭 등을 산정한 후 자료의 적합도 검정과 결합분포의 적합도 검정 등의 과정을 거쳐 첨두홍수량과 홍수용적의 조합을 고려하여 결합분포와 결합 재현기간 등을 추정하였다. 이처럼 세 가지 방법의 이변량 빈도해석을 통해 추정된 결과를 단변량 홍수빈도 해석의 결과와 비교 분석함으로써 각 방법의 상관성을 파악할 수 있었고, 이변량 홍수빈도 해석의 특성에 의해 도출된 결과를 토대로 이변량 홍수빈도 해석의 적용성에 대하여 검토하였다.

원유광(源油鑛)의 규모 및 추정을 위한 자기장(磁氣場)의 통계적 분석(統計的 分析) (A statistical analysis of magnetic field intensities for estimating the size and orientation of the petroleum deposit)

  • 전덕빈
    • 산업공학
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    • 제1권1호
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    • pp.9-15
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    • 1988
  • A statistical analysis for detecting deviations from normal magnetic field intensities, caused by the introduction of magnetite materials into man-made fissures and cracks at subsurface levels is presented. For detecting such deviations it turns out the comparison of two different field measurements measured at two different sites far from each other is more efficient than the study of the only measurement by the univariate and bivariate time series analysis.

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관상동맥 우회로 조성수술후 발생하는 심 방세동의 위험요인 분석 (Analysis of risk factors of atrial fibrillation after coronary artery bypass grafting)

  • 유경종;고영호;임상현;강면식
    • Journal of Chest Surgery
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    • 제29권6호
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    • pp.599-605
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    • 1996
  • 연세대학교심장혈관 센터에서는 1990년 1월 부터 1994년 12월까지 281명의 관상동맥 우회로수술을 시행하였으며 이중 수술전 심방세동이 있던 환자,판막질환 수술 및 심근경색의 합병증의 수술을 병행 하였던 환자 32명을 제외한 249명에 대해 수술전,수술시 및 수술후 심방세동 발생의 위험요인에 대해 분석하였다. 대상환자의 연령은 24세에서 78세 사이로 평균 58.2$\pm$9.)세 였으며,남자가 182명, 여자가 67명 이었 다. 제 1군에 속하는 환자는 38명(15%) 이 었고 제 2군에 속하는 환자는 211명(85%) 이었다. 수술후 심방 세동이 발생한 시간은 환자가 중환자실에 도착한 후 8시간에서 336시간 사이에 발생하여 평균 59.1 $\pm$56. 9 시간 이 었으며(median time : 48 hours), 정상 동 율동으로 돌아온 시간은 심방세동이 발생한 후 1시간 에서 144시간 사이로 평균 26.7 $\pm$33.9시간이었다(median time : 12.5 hours). 퇴원시 심방세동을 보였던 모든 환자는 정상 동율동을 보였다. 심방세동이 발생하기 전과 발생한 직후 측정한 심박출계수는 발생 전 평균 3.9$\pm$ 1.1 L/min/m.에서 발생직후 3.2$\pm$ 1.1 L/min/m'로 통계 학적으로 유의하게 감소하였다(p=0. 001). 분 \ulcorner嘯\ulcorner통계학적인 유의성을 가진 변수는 univariate analysis 에서 수술전 좌심실 박출계수, triglyceride 수치, 수술후 측정한 peak CKMB isoenzyme, 심방 pacing의 여부, 입원기간 및 만기사망이 었 다. 좌심실 박출계수(p=0.025), triglyceride 수치(p=0.006) 및 peak CKMB isoenzyme(p=0.002)은 낮은 경 우에 심방세동의 발생이 증가하였으며,심방 pacing을 찬 경우에 심방세동의 발생이 증가하였다(p=0. 001). 또한 심방세동이 발생한 군에서 입원기간이 길었으며(p=0.001), 만기사망이 많았다(p=0.033). Multivariate analysis 에서 통계학적인 유의성을 보이는 변수는 수술전 체중과 심방 pacing의 여부였다. 체중은 많이 나갈수록 심방세동의 발생 이 .증가하였으며(p=0.011), 심방 pacing을 한 경우에 심방세동의 발생이 증가하였다(p=0.001). Univariate 및 multivariate analysis 에서 환자의 나이는 통계학적인 유의성 을 보이지는 않았지만 나이가 증가할수록 심방세동의 발생이 증가하는 경향을 보여주고 있다(p=0.053, p=0.064). 평균 추적기간은 30.1 $\pm$ 15.4 개월이었으며, 추적율은 98%였다. 이 기간 동안 심방세동을 보일 예는 없었다. 연구결과 수술 \ulcorner발생하는 심방세동은 어느 한가지 요인에 의해서라기 보다는 여러가지 요인이복합 적으로 작용하여 나타나는 것으로 생각된다. 또한 수술후 나타나는 심방세동은 혈동학적 인 장애를 유발 할 뿐만 아니라 입원기간을 증가시키고, 만기사망을 증가시키므로 위험요소가 있거나 위험요소가 발생 시 적극적 인 예방이나 치료가 필요할 것으로 생각된다.

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Dietary Patterns and Health Behaviors of Hypertensive Korean Adults

  • Kim, Youngok;Lee, Soon-Young
    • Preventive Nutrition and Food Science
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    • 제7권2호
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    • pp.201-206
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    • 2002
  • Findings from European and American studies have indicated such health behaviors as smoking, drinking, lack of exercise, and insufficient intake of grains, fruits and vegetables as risk factors for hypertension. However, because dietary pattern and health behaviors of Korean differ from people of other countries, the risk factors for Koreans could be different. Therefore, the aim of this study was to identify food consumption patterns and health behavior characteristics of Korean hypertensive adults. Data on food consumptions and other health behaviors such as smoking, drinking, and exercise together with development of hypertension were collected from 597 persons aged 20 to 69 years in a local community. The first stage of analysis utilized cluster analysis to aggregate individuals into different health behavior and food consumption groups. Four health behavior groups were characterized by passive cluster, smoker cluster, fitness cluster and drinker cluster. Food consumption patterns of the subjects were also aggregated into 4 different clusters: dairy cluster, grain & vegetable cluster, fruit cluster, and fish & meat cluster. Then univariate analysis was followed to identify the variables associated with hypertension. The final stage of analysis was the identification of the relative importance of the variables selected from the univariate analysis on hypertension, using multiple logistic analysis. The results showed that heavy drinking was the most significant health behavior associated hypertension, which was similar to the findings in European and American studies. However, unlike the findings from foreign studies, grain and vegetable consumption appeared to be a risk factor for hypertension. A possible reason for the contradictory results between Korean and Western studies may be the dependence of Koreans on white rice as the major staple food, and/or the frequent consumption of salted vegetables, rather than fresh vegetables as is customary in Europe and America.

단변량 및 이변량 순위변수의 비모수적 윌콕슨 검정법에 의한 표본수 결정방법 (Sample Size Determination of Univariate and Bivariate Ordinal Outcomes by Nonparametric Wilcoxon Tests)

  • 박해강;송혜향
    • 응용통계연구
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    • 제22권6호
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    • pp.1249-1263
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    • 2009
  • 표본수 결정에서 요구되는 검정력 함수는 연구가설에 상응하는 가장 적절한 검정방법에 의한 것이어야 한다. 의학연구의 논문에 자주 나타나는 순위자료 또는 범주형 빈도자료의 분석에는 비모수적 방법이 적절하며, 본 논문에서는 단변량 및 이변량 순위변수에 대한 윌콕슨-만-휘트니(Wilcoxon-Mann-Whitney; WMW) 검정법에 의한 표본수 결정방법을 제시한다. 단변량 순위변수의 윌콕슨 검정에서는 귀무가설과 대립가설 하의 분산을 이용한 표본수 공식이 귀무가설 하의 분산만 이용한 표본수 공식보다 정확하지만, 대립가설 하의 분산식에 나타나는 확률값이 일반적으로 알려져 있지 않으므로 이 확률값의 추정이 문제가 된다. 모의실험으로 두 방법에 대한 장, 단점을 알아본다. 효능과 안전성의 이변량 순위변수에서는 이변량 WMW 검정법에 의한 표본수 결정방법이 모수적 검정법에 의한 표본수 결정방법보다 더욱 바람직하다.

Multivariate design estimations under copulas constructions. Stage-1: Parametrical density constructions for defining flood marginals for the Kelantan River basin, Malaysia

  • Latif, Shahid;Mustafa, Firuza
    • Ocean Systems Engineering
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    • 제9권3호
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    • pp.287-328
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    • 2019
  • Comprehensive understanding of the flood risk assessments via frequency analysis often demands multivariate designs under the different notations of return periods. Flood is a tri-variate random consequence, which often pointing the unreliability of univariate return period and demands for the joint dependency construction by accounting its multiple intercorrelated flood vectors i.e., flood peak, volume & durations. Selecting the most parsimonious probability functions for demonstrating univariate flood marginals distributions is often a mandatory pre-processing desire before the establishment of joint dependency. Especially under copulas methodology, which often allows the practitioner to model univariate marginals separately from their joint constructions. Parametric density approximations often hypothesized that the random samples must follow some specific or predefine probability density functions, which usually defines different estimates especially in the tail of distributions. Concentrations of the upper tail often seem interesting during flood modelling also, no evidence exhibited in favours of any fixed distributions, which often characterized through the trial and error procedure based on goodness-of-fit measures. On another side, model performance evaluations and selections of best-fitted distributions often demand precise investigations via comparing the relative sample reproducing capabilities otherwise, inconsistencies might reveal uncertainty. Also, the strength & weakness of different fitness statistics usually vary and having different extent during demonstrating gaps and dispensary among fitted distributions. In this literature, selections efforts of marginal distributions of flood variables are incorporated by employing an interactive set of parametric functions for event-based (or Block annual maxima) samples over the 50-years continuously-distributed streamflow characteristics for the Kelantan River basin at Gulliemard Bridge, Malaysia. Model fitness criteria are examined based on the degree of agreements between cumulative empirical and theoretical probabilities. Both the analytical as well as graphically visual inspections are undertaken to strengthen much decisive evidence in favour of best-fitted probability density.

Survival Analysis and Prognostic Factors for Colorectal Cancer Patients in Malaysia

  • Hassan, Muhammad Radzi Abu;Suan, Mohd Azri Mohd;Soelar, Shahrul Aiman;Mohammed, Noor Syahireen;Ismail, Ibtisam;Ahmad, Faizah
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권7호
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    • pp.3575-3581
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    • 2016
  • Background: Cancer survival analysis is an essential indicator for effective early detection and improvements in cancer treatment. This study was undertaken to document colorectal cancer survival and associated prognostic factors in Malaysians. Materials and Methods: All data were retrieved from the National Cancer Patient Registry-Colorectal Cancer. Only cases with confirmed diagnosis through histology between the year 2008 and 2009 were included. Retrieved data include socio-demographic information, pathological features and treatment received. Survival curves were plotted using the Kaplan-Meier method. Univariate analysis of all variables was then made using the Log-rank test. All significant factors that influenced survival of patients were further analysed in a multivariate analysis using Cox' regression. Results: Total of 1,214 patients were included in the study. The overall 3- and 5-year survival rates were 59.1% and 48.7%, respectively. Patients with localized tumours had better prognosis compared to those with advanced stage cancer. In univariate analysis, staging at diagnosis (p<0.001), primary tumour size (p<0.001), involvement of lymph nodes (p<0.001) and treatment modalities (p=0.001) were found to be predictors of survival. None of the socio-demographic characteristics were found to exert any influence. In Cox regression analysis, staging at diagnosis (p<0.001), primary tumour size (p<0.001), involvement of lymph nodes (p<0.001) and treatment modalities (p<0.001) were determined as independent prognostic factors of survival after adjusted for age, gender and ethnicity. Conclusions: The overall survival rate for colorectal cancer patients in Malaysia is similar to those in other Asian countries, with staging at diagnosis, primary tumor size, involvement of lymph node and treatment modalities having significant effects. More efforts are needed to improve national survival rates in future.